|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Antimicrobial potential of Actinomycetes species isolated from marine environment显示文摘Objective:To evaluate the antimicrobial activity of Actinomycetes species isolated from marine environment.Methods:Twenty one strains of Actinomyceteswere isolated from samples of Royapuram, Muttukadu, Mahabalipuram sea shores and Adyar estuary. Preliminary screening was done using cross-streak method against two gram-positive and eight gram-negative bacteria.The most potent strains C11 and C12 were selected from which antibacterial substances were extracted. The antibacterial activities of the extracts were performed using Kirby-Bauer disc diffusion method. Molecular identification of those isolates was done.Results:All those twenty one isolates were active against at least one of the test organisms. Morphological characters were recorded. C11 showed activity againstStaphylococcusspecies(13.0暲0.5 mm),Vibrio harveyi(11.0暲0.2 mm),Pseudomonas species(12.0暲0.3 mm). C12 showed activity against Staphylococcus species(16.0暲0.4 mm),Bacillus subtilis(11.0暲0.2 mm),Vibrio harveyi(9.0暲0.1 mm),Pseudomonas species(10.0暲0.2 mm). 16S rRNA pattern strongly suggested that C11 and C12 strains were Streptomyces species.Conclusions:The results of the present investigation reveal that the marineActinomycetesfrom coastal environment are the potent source of novel antibiotics.Isolation, characterization and study of Actinom ycetescan be useful in discovery of novel species of Actinomy cetes. | Valli S Suvathi Sugasini S Aysha OS Nirmala P Vinoth Kumar P Reena A | 2012 | Asian Pacific Journal of Tropical Biomedicine2012，2，6： | 8 |
| 2 | Anti-microbial principles of selected remedial plants from Southern India显示文摘Objective:To examine the anti-bacterial activity of leaf extracts of Morus alba L.(Moraceae)and Piper betel L.(Piperaceae),and seed extracts of Bombax ceiba L.(Borabacaceae).Methods:We have partially purified plant extracts by solvent extraction method,and evaluated the effect of individual fractions on bacterial growth using Escherichia coli(E.coli),Pseudomonas aeruginosa(P.aeruginosa) and Staphylococcus aureus(S.aureus) bacterial strains.Results:Compared with Morus and Bombax fractions,Piper fractions showed significant growth inhibition on all the three types of bacteria studied.The EtOAc-hexane fractions of Piper leaves exhibited significant antibacterial activity with minimum inhibitory concentrations(MIC) of 50 μg/mL culture against both gram-positive and gram-negative bacteria.The EtOAc-fractions Ⅰ,Ⅱ,and Ⅳ inhibited bacterial colony formation on soft agar in addition to growth inhibition.A combination treatment of piper fractions with ampicillin resulted in significant growth inhibition in E.coli and P.aeruginosa,and combination with anticancer drug geldanamycin(2 μg/mL) showed selective growth inhibition against P.aeruginosa and S.aureus.Three major compounds,i.e.,eugenol,3-hexene-ol and stigmasterol,were primarily identified from Piper betel leaf extractions.Among the individual compounds,eugenol treatment showed improved growth inhibition compared with stigmasterol and 3-hexene-ol.Conclusions:We are reporting potential anti-bacterial compounds from Piper betel against both gram-positive and gram-negative bacteria either alone or in combination with drug treatment. | Tirupathi Rao G Suresh Babu K J Ujwal Kumar Sujana P A Veerabhadr Raoa Sreedhar AS | 2011 | Asian Pacific Journal of Tropical Biomedicine2011，1，4： | 5 |
| 3 | Genetic determinant s of diabetic nephropathy显示文摘 | Chowdhury T A Dyer P H Kumar S | | 0，，： | 2 |
| 4 | Phytoextraction:the use of plants to remove heavy metals from soils显示文摘 | NADAN KUMAR P B A DUSHENKOV V MOTTO H | 1995 | Environ Sci Technol1995，29，5： | 2 |
| 5 | A lupane derivative and the 13C-NMR chemical shifts lupanone from Pleurostylia opposita 显示文摘 | Dantanarayana A P Kumar N S | 1982 | Phytochemistry1982，21，8： | 2 |
| 6 | Objectively determined 10-day African rainfall estimates created for famine early warning systems显示文摘 | Herman A V B Kumar P A Arkin | 1997 | Int J Remote Sens1997，18，： | 2 |
| 7 | Phytoremediation:The use of plants to remove heavy metals from soils 显示文摘 | Nanda - Kumar P B A Dushenkov V Motto H | 1995 | Environmental Science & Technology1995，29，5： | 2 |
| 8 | Antioxidant activity and haemolysis prevention efficiency of polyaniline nanofibers显示文摘 | Somik Banerjee Jyoti P Saikia A Kumar B K Konwar | 2010 | Nanotechnology2010，，4： | 2 |
| 9 | Non-destructive method of leaf-area determination in ash gourd ( Benincasa hispida) 显示文摘 | Radhakrishnan V V Kumar P G S Oommen A | 1991 | Indian Journal of Agricultural Sciences1991，61，1： | 1 |
| 10 | Rapid techniques for determination of free lime and free magnesia in cement clinker and portlandite in hydrates 显示文摘 | Arjunan P Kumar A | 1994 | Cement and Concrete Research1994，24，2： | 1 |
| 11 | Histological analysis of lesions of the pineal region:a retrospective study of 12 years显示文摘 | Kumar P Tatke M Sharma A | 2006 | Pathol Res Pract2006，202，2： | 1 |
| 12 | Genetic variants of platelet glycoprotein receptors and risk of stroke in young women 显示文摘 | Reiner A P Kumar P M Schwartz S M | 2000 | Stroke2000，31，7： | 1 |
| 13 | Performance of a magnesium-lithium alloy as an anode for magnesium batteries显示文摘 | SIVASHANMUGAM A KUMAR T P RENGANATHAN N G | 2004 | J Appl Electrochem2004，34，： | 1 |
| 14 | An approach to the estimation of the value of agricultural residues used as biofuels 显示文摘 | Kumar A Purohit P Rana S | 2002 | Biomass & Bioenergy2002，22，3： | 1 |
| 15 | Combretastatin A-4 analogs as anticancer agents显示文摘 | Chaudhary A Pandeya S N Kumar P | 2007 | Mini Rev Med Chem2007，7，12： | 1 |
| 16 | Endothelin and endothelin antagonism : roles in eardiovase ular health and disease 显示文摘 | Tamirisa P Frishman WH Kumar A | 1995 | Am Heart J1995，130，： | 1 |
| 17 | Double-stranded RNA-mediated gene silencing ofcysteine proteases (falcipain-1and-2) of Plasmodiumfalciparum显示文摘 | Malhotra P Dasaradhi PV Kumar A et ol | 2002 | Mol Microbiol2002，45，5： | 1 |
| 18 | Computer Simulation of Transport Processes During Injection Mold-Filling and Optimization of the Molding Conditions显示文摘 | Kumar A Ghoshdastidar P S Muju M K | 2002 | Journal of Materials Processing Technology2002，120，3： | 1 |
| 19 | Biosynthesis of bacterial glycogen显示文摘 | Kumar A Ghosh P Lee Y M | 1989 | J of Biol Chem1989，264，10： | 1 |
| 20 | Massive primary chylopericardium in an infant显示文摘 | Anil SR Manoj P Hejmadi A Kumar RK | 2002 | Indian Heart J2002，54，3： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员