|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | S-1 plus cisplatin versus S-1 alone for first-line treatment of advanced gastric cancer (SPIRITS trial): a phase III trial显示文摘 | Wasaburo Koizumi Hiroyuki Narahara Takuo Hara Akinori Takagane Toshikazu Akiya Masakazu Takagi Kosei Miyashita Takashi Nishizaki Osamu Kobayashi Wataru Takiyama Yasushi Toh Takashi Nagaie Seiichi Takagi Yoshitaka Yamamura Kimihiko Yanaoka Hiroyuki Orita M | 2008 | Lancet Oncology2008，，3： | 12 |
| 2 | Novel risk markers for gastric cancer screening: Present status and future prospects显示文摘Initial identification of populations at high risk of gastric cancer (GC) is important for endoscopic screening of GC. As serum pepsinogen (PG) test-positive subjects with progression of chronic atrophic gastritis (CAG) show a high likelihood of future cancer development, this population warrants careful follow-up observation as a high-risk GC group. By combining the PG test with Helicobacter pylori (HP) antibody titers, the HP-related chronic gastritis stage can be classified, thus identifying not only a GC high-risk group but also a low-risk group. Among PG test-negative patients without CAG, those with high serum PG Ⅱ levels and HP antibody titers are thought to have severe gastric mucosal inflammation and the risk of diffuse-type GC is also high. Meanwhile, in gastric mucosae obtained by endoscopic biopsy, HP infection induces aberrant DNA methylation in CpG islands in multiple gene regions and the extent of methylation clearly correlates with GC risk. By quantifying aberrant DNA methylation in suitable gene markers, we can determine the extent of the epigenetic field for cancerization. These novel concepts and risk markers will have many clinical applications in gastrointestinal endoscopy, including more efficient endoscopic GC screening and a strategic approach to metachronous multiple GCs after endoscopic treatment. | Shotaro Enomoto Takao Maekita Hiroshi Ohata Kimihiko Yanaoka Masashi Oka Masao Ichinose | 2010 | World Journal of Gastrointestinal Endoscopy2010，2，12： | 10 |
| 3 | Clinical benefit of surgery for stage IV colorectal cancer with synchronous peritoneal metastasis显示文摘 | Hirotoshi Kobayashi Kenjiro Kotake Kimihiko Funahashi Kazuo Hase Koichi Hirata Tsuneo Iiai Shingo Kameoka Yukihide Kanemitsu Koutarou Maeda Akihiko Murata Masayuki Ohue Kazuo Shirouzu Keiichi Takahashi Toshiaki Watanabe Hideaki Yano Toshimasa Yatsuoka Yoj | 2014 | Journal of Gastroenterology2014，，4： | 2 |
| 4 | An Nrf2/Small Maf Heterodimer Mediates the Induction of Phase II Detoxifying Enzyme Genes through Antioxidant Response Elements显示文摘 | Ken Itoh Tomoki Chiba Satoru Takahashi Tetsuro Ishii Kazuhiko Igarashi Yasutake Katoh Tatsuya Oyake Norio Hayashi Kimihiko Satoh Ichiro Hatayama Masayuki Yamamoto Yo-ichi Nabeshima | 1997 | Biochemical and Biophysical Research Communications1997，，2： | 2 |
| 5 | Occurrence of N-methyl-l-aspartate in bivalves and its distribution compared with of N-methyl-D-aspartate and D, L-aspartate 显示文摘 | Kimihiko S Atsuko T | 2001 | Compar Biochem Physiol Part B2001，130，： | 2 |
| 6 | Hand Assisted Retroperitoneoscopic Nephroureterectomy: Comparison With the Open Procedure显示文摘 | AKIHIRO KAWAUCHI AKIRA FUJITO OSAMU UKIMURA KIMIHIKO YONEDA YOICHI MIZUTANI TSUNEHARU MIKI | 2003 | The Journal of Urology2003，，3： | 2 |
| 7 | S-1 plus cisplatin versus S-1 alone for first-line treatment of advanced gastric cancer (SPIRITS trial): a phase III trial显示文摘 | Wasaburo Koizumi Hiroyuki Narahara Takuo Hara Akinori Takagane Toshikazu Akiya Masakazu Takagi Kosei Miyashita Takashi Nishizaki Osamu Kobayashi Wataru Takiyama Yasushi Toh Takashi Nagaie Seiichi Takagi Yoshitaka Yamamura Kimihiko Yanaoka Hiroyuki Orita M | 2008 | Lancet Oncology2008，，3： | 2 |
| 8 | Analysis of α and β-tubulin genes of Bombyx mori using an EST database显示文摘 | Hideki K Kimihiko S Guo Xing Q | 2003 | Insect Biochemy Mol Biol2003，33，： | 1 |
| 9 | Self-powered active vibration control using a single electric actuator 显示文摘 | KIMIHIKO N | 2003 | Journal of Sound and Vibration2003，260，2： | 1 |
| 10 | The anti-proliferative effect of proliferating cell nuclear antigen-specific antisense oligonucleotides on human gastric cancer cell lines显示文摘 | Chouhei Sakakura Akeo Hagiwara Hiroyuki Tsujimoto Kimihiko Ozaki Tsuguo Sakakibara Takayuki Oyama Masaharu Ogaki Toshio Takahashi | 1995 | Surgery Today1995，，2： | 1 |
| 11 | S-1 plus cisplatin versus S-1 alone for first-line treatment of advanced gastric cancer (SPIRITS trial): a phase III trial显示文摘 | Wasaburo Koizumi Hiroyuki Narahara Takuo Hara Akinori Takagane Toshikazu Akiya Masakazu Takagi Kosei Miyashita Takashi Nishizaki Osamu Kobayashi Wataru Takiyama Yasushi Toh Takashi Nagaie Seiichi Takagi Yoshitaka Yamamura Kimihiko Yanaoka Hiroyuki Orita M | 2008 | Lancet Oncology2008，，3： | 1 |
| 12 | Significance of Clinical–Diffusion Mismatch in Hyperacute Cerebral Infarction显示文摘 | Ichiro Deguchi Hidetaka Takeda Daisuke Furuya Kimihiko Hattori Tomohisa Dembo Harumitsu Nagoya Yuji Kato Takuya Fukuoka Hajime Maruyama Norio Tanahashi | 2011 | Journal of Stroke and Cerebrovascular Diseases2011，，1： | 1 |
| 13 | Association of plasma atrial natriuretic peptide,N-Terminal proetrial natriuretic peptide,and brain natriuretic peptide levels with coronary artery stenosis in patients with normal left ventricular systolic function显示文摘 | Toshio N Yosuke M Kimihiko I | 2004 | Am J Med2004，116，： | 1 |
| 14 | Multiresidue analysis of pesticides in fresh fruits and vegetables by supercritical fluid Extraction and HPLC显示文摘 | Akiko Kaihara Kimihiko Yoshii Yukari Tsumura | 2000 | Journal of Health Science2000，46，5： | 1 |
| 15 | Self-powered active vibration control using a single electric actuator 显示文摘 | NAKANO Kimihiko SUDA Yoshihiro NAKADAI Shigeyuki | 2003 | Journal of Sound and Vibration2003，260，2： | 1 |
| 16 | Differentiation of dementia with Lewy bodies from Alzheimer’s disease using Mini-Mental State Examination and brain perfusion SPECT显示文摘 | Haruo Hanyu Soichiro Shimizu Kentaro Hirao Hidekazu Kanetaka Hirofumi Sakurai Toshihiko Iwamoto Kiyoshi Koizumi Kimihiko Abe | 2006 | Journal of the Neurological Sciences2006，，1： | 1 |
| 17 | Substituent distribution in cellulose acetates: Its control and the effect on structure formation in solution显示文摘 | Tsunashima Yoshisuke Hattori Kimihiko | 2000 | J Colloid Interface Sci2000，288，： | 1 |
| 18 | Analysis of Chatter Vibration in an Automotive Wiper Assembly 显示文摘 | Ryosuke Suaki Kimihiko Yasuda | 1998 | JSAE International Jour- nal1998，41，3： | 1 |
| 19 | Effects of the oral administrationof green tea polyphenol and tannic acid on serum and hepatic lipidcontents and fecal steroid excretion in rats显示文摘 | YUMIKO N AKIKO K KIMIHIKO Y | 2001 | J Health Sci2001，47，2： | 1 |
| 20 | Gastric cancer screening of a high-risk population in Japan using serum pepsinogen and barium digital radiography显示文摘 | Hiroshi O Masashi O Kimihiko Y | 2005 | Cancer Sci2005，96，10： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员