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| 1 | 手术期间血糖控制对糖尿病视网膜病变和黄斑病变的影响显示文摘目的:评估手术期间血糖控制对糖尿病视网膜病变和黄斑病变进展的影响。 | Chikako Suto Sadao Hori SatoshI Kato Kanemitsu Muraoka Shigehiko Kitano 刘亮(译) | 2006 | 美国医学会眼科杂志(中文版)2006，18，4： | 16 |
| 2 | 原发灶切除+化疗与单独化疗治疗存在无症状、同时性、不可切除转移灶的结直肠癌患者的疗效对比--一项随机临床试验(JCOG1007;iPACS)显示文摘目的:关于在原发灶切除术(primary tumor resection,PTR)后进行化疗能否改善存在无症状的原发灶及同时性、不可切除转移灶的结直肠癌患者的生存情况,目前仍有争议。方法:本试验为关于PTR后进行化疗对比单独化疗治疗结直肠癌患者总生存(overall survival,OS)情况的Ⅲ期随机研究,入组患者(Ⅳ期)存在无症状的不可切除的转移灶,转移灶位于肝、肺、远处淋巴结或腹膜,数量为3个及以下。所采用的化疗方案在入组前已决定,包括mFOLFOX6+贝伐珠单抗或者CapeOX+贝伐珠单抗。主要研究终点是意向治疗人群的OS。 | 俞少俊 KANEMITSU Y SHITARA K MIZUSAWA J | 2021 | 结直肠肛门外科2021，27，2： | 12 |
| 3 | Japanese Society for Cancer of the Colon and Rectum (JSCCR) guidelines 2010 for the treatment of colorectal cancer显示文摘 | Toshiaki Watanabe Michio Itabashi Yasuhiro Shimada Shinji Tanaka Yoshinori Ito Yoichi Ajioka Tetsuya Hamaguchi Ichinosuke Hyodo Masahiro Igarashi Hideyuki Ishida Megumi Ishiguro Yukihide Kanemitsu Norihiro Kokudo Kei Muro Atsushi Ochiai Masahiko Oguchi Ya | 2012 | International Journal of Clinical Oncology2012，，1： | 5 |
| 4 | 传统技术与不接触隔离技术在结肠癌原发肿瘤切除中的应用对比(JCOG1006):一项多中心、开放、随机、Ⅲ期试验显示文摘目的:这项Ⅲ期试验目的是评估不接触隔离技术(no-touchisolation technique,NTIT)在c T3/T4结肠癌患者中是否优于传统技术(conventional technique,Co T)。方法:这项开放、随机的Ⅲ期试验在日本30个医学中心进行。纳入标准:组织学证实为结肠癌;临床分期为T3~4期、N0~2期、M0期;患者年龄20~80岁。患者随机(1:1)接受采用Co T或NTIT的开放式手术。病理分期为Ⅲ期的患者接受卡培他滨辅助化疗。 | 李绍堂 TAKII Y MIZUSAWA J KANEMITSU Y | 2022 | 结直肠肛门外科2022，28，2： | 5 |
| 5 | Clinical benefit of surgery for stage IV colorectal cancer with synchronous peritoneal metastasis显示文摘 | Hirotoshi Kobayashi Kenjiro Kotake Kimihiko Funahashi Kazuo Hase Koichi Hirata Tsuneo Iiai Shingo Kameoka Yukihide Kanemitsu Koutarou Maeda Akihiko Murata Masayuki Ohue Kazuo Shirouzu Keiichi Takahashi Toshiaki Watanabe Hideaki Yano Toshimasa Yatsuoka Yoj | 2014 | Journal of Gastroenterology2014，，4： | 2 |
| 6 | Pretreatment AKR1B10 expression predicts the risk of hepatocellular carcinoma development after hepatitis C virus eradication显示文摘AIM To clarify the association between aldo-keto reductase family 1 member B10(AKR1B10) expression and hepatocarcinogenesis after hepatitis C virus eradication.METHODS In this study,we enrolled 303 chronic hepatitis C patients who had achieved sustained virological response(SVR) through interferon-based antiviral therapy. Pretreatment AKR1B10 expression in the liver was immunohistochemically assessed and quantified as a percentage of positive staining area by using image-analysis software. A multivariate Cox analysis was used to estimate the hazard ratios(HRs) of AKR1B10 expression for hepatocellular carcinoma(HCC) development after achieving SVR. The cumulative incidences of HCC development were evaluated using Kaplan-Meier analysis and the log-rank test.RESULTS Of the 303 chronic hepatitis C patients,153(50.5%) showed scarce hepatic AKR1B10 expression,quantified as 0%,which was similar to the expression in control normal liver tissues. However,the remaining 150 patients(49.5%) exhibited various degrees of AKR1B10 expression in the liver,with a maximal AKR1B10 expression of 73%. During the median follow-up time of 3.6 years(range 1.0-10.0 years),8/303 patients developed HCC. Multivariate analysis revealed that only high AKR1B10 expression(≥ 8%) was an independent risk factor for HCC development(HR = 15.4,95%CI: 1. 8- 1 3 2. 5,P = 0. 0 1 2). T h e 5- y e a r c u m u l a t i v e incidences of HCC development were 13.7% and 0.5% in patients with high and low AKR1B10 expression,respectively(P < 0.001). During the follow-up period after viral eradication,patients expressing high levels of AKR1B10 expressed markedly higher levels of alanine aminotransferase and α-fetoprotein than did patients exhibiting low AKR1B10 expression.CONCLUSION Chronic hepatitis C patients expressing high levels of hepatic AKR1B10 had an increased risk of HCC development even after SVR. | Ayato Murata Takuya Genda Takafumi Ichida Nozomi Amano Sho Sato Hironori Tsuzura Shunsuke Sato Yutaka Narita Yoshio Kanemitsu Yuji Shimada Katsuharu Hirano Katsuyori Iijima Ryo Wada Akihito Nagahara Sumio Watanabe | 2016 | World Journal of Gastroenterology2016，22，33： | 2 |
| 7 | Long-term outcomes of extended radical resection combined with intraoperative radiation therapy for pancreatic cancer显示文摘 | Hiroshi Takamori Takehisa Hiraoka Keiichiro Kanemitsu Tatsuya Tsuji Hiroshi Tanaka Akira Chikamoto Kei Horino Toru Beppu Masahiko Hirota Hideo Baba | 2008 | Journal of Hepato - Biliary - Pancreatic Surgery2008，，6： | 2 |
| 8 | Quantitative Detection of Disseminated Free Cancer Cells in Peritoneal Washes With Real-Time Reverse Transcriptase–Polymerase Chain Reaction: A Sensitive Predictor of Outcome for Patients With Gastric Carcinoma显示文摘 | Yasuhiro Kodera Hayao Nakanishi Seiji Ito Yoshitaka Yamamura Yukihide Kanemitsu Yasuhiro Shimizu Takashi Hirai Kenzo Yasui Tomoyuki Kato Masae Tatematsu | 2002 | Annals of Surgery2002，，4： | 2 |
| 9 | 肝切除术后联合mFOLFOX6辅助化疗与单独肝切除术治疗仅肝转移性结直肠癌的比较研究(JCOG0603):一项Ⅱ期或Ⅲ期随机对照研究显示文摘研究目的:目前,仅肝转移性结直肠癌(LM-CRC)患者肝切除术后是否需行辅助化疗仍颇受争议。本研究的目的是通过随机对照研究探讨肝切除术后联合mFOLFOX6辅助化疗治疗LM-CRC的效果是否优于单独肝切除术。研究对象和研究方法:在这项Ⅱ期或Ⅲ期随机对照研究(JCOG0603)中,年龄在20~75岁。 | 俞旻皓 KANEMITSU Y SHIMIZU Y MIZUSAWA J | 2021 | 结直肠肛门外科2021，27，6： | 2 |
| 10 | Rotor vibration due to collision with annular guard during passage through critical speed 显示文摘 | Yanabe S Kaneko S Kanemitsu Y Tomi N Sugiyama K | 1998 | ASME Journal of Vibration and Acoustics1998，120，： | 1 |
| 11 | Transformation and Stat activation by derivatives of FGFR1, FGFR3, FGFR4显示文摘 | Hart KC Robertson SC Kanemitsu MY | 2000 | Oncogene2000，19，29： | 1 |
| 12 | Sensitization of photocatalytic activity of S- or N-doped TiO 2 particles by adsorbing Fe 3+ cations显示文摘 | Teruhisa Ohno Zenta Miyamoto Kazumoto Nishijima Hidekazu Kanemitsu Feng Xueyuan | 2005 | Applied Catalysis A, General2005，，： | 1 |
| 13 | A 17-mer peptide interferes with acidification-induced uncoupling of connexin43 显示文摘 | Calero G Kanemitsu M Taffet SM | 1998 | Circ Res1998，82，： | 1 |
| 14 | Early recovery of protein synthesis following ischemia in hippocampal neurons with induced tolerance in the gebil显示文摘 | Nakagomi T Kirino T Kanemitsu H | 1993 | Acta Neuropathol1993，86，1： | 1 |
| 15 | Survival benefit of high ligation of the inferiormesenteric artery in sigmoid colon or rectal cancer surger-y显示文摘 | Kanemitsu Y Hirai T Komori K | | 0，，： | 1 |
| 16 | Concentrations of 5-fluorouracil (5-Fu) in serum and tissues at venous injection of tegafur or 5-Fu-clinical study on colorectal cancer显示文摘 | Kojima T Suzumura K Kanemitsu T | 1998 | Gan To Kagaku Ryoho1998，25，4： | 1 |
| 17 | Fabrication and Photoluminescence Studies of ZnO Nanocrystals Dispersed in Glass Films显示文摘 | Yamamoto A Atsuta S Kanemitsu Y | 2005 | Journal of Luminescence2005，112，： | 1 |
| 18 | Key of induced tolerance to ischaemia in gerbil hippocampal CA1 is not at transcriptional level of hsp70 g ene: in situ hybridization of hsp70 mRNA 显示文摘 | Kirino T Nakagomi T | 1994 | Neurol Res1994，16，： | 1 |
| 19 | Preoperative probability model for predicting overall survival after resection of pulmonary metastases from colorectal cancer显示文摘 | Kanemitsu Y Kato T Hirai T | | 0，，： | 1 |
| 20 | 5-fluorouracil Intra-ar terial Infusion Combined with Systemic Gemcitabine for Unresectable Pancreatic Cancer显示文摘 | Takamori H Kanemitsu K Tsuji T | 2005 | Pancreas2005，30，3： | 1 |
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