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| 1 | Arsenic trioxide promotes senescence and regulates the balance of adipogenic and osteogenic differentiation in human mesenchymal stem cells显示文摘砷三氧化物(ATO ) 能在肿瘤房间作为反肿瘤药导致区别和 apoptosis。间充质的干细胞(MSC ) 在骨头髓的造血作用起重要作用。许多报告证明了 MSC adipogenic 和 osteogenic 区别的混乱发生在一些疾病。然而,关于 MSC 上的 ATO 的效果的报告是有限的。在这研究,我们发现 1 M ATO 主要通过 p21 支持了 MSC 老朽,尽管它没在这剂量在 apoptosis 上有效果。而且, ATO 支持了 adipogenic 区别,但是在 MSC 禁止了 osteogenic 区别。我们的学习也显示出那 CCAAT/enhancer-binding 蛋白质 alpha C/EBP 和 peroxisome 激活 proliferator 的受体 gamma PPAR 可能涉及 ATO 导致的 adipogenic 和 osteogenic 区别的规定。我们的结果显示 ATO 可以由影响骨头髓微型环境施加反肿瘤效果。而且,它可以调整 MSC 的 adipogenic 和 osteogenic 区别。 | Huanchen Cheng Lin Qiu Hao Zhang Mei Cheng Wei Li Xuefei Zhao Keyu Liu Lei Lei Jun Ma | 2011 | Acta Biochimica et Biophysica Sinica2011，43，3： | 8 |
| 2 | Construction of a small-caliber tissue-engineered blood vessel using icariin-loaded β-cyclodextrin sulfate for in situ anticoagulation and endothelialization显示文摘The rapid endothelialization of tissue-engineered blood vessels(TEBVs) can effectively prevent thrombosis and inhibit intimal hyperplasia. The traditional Chinese medicine ingredient icariin is highly promising for the treatment of cardiovascular diseases.β-cyclodextrin sulfate is a type of hollow molecule that has good biocompatibility and anticoagulation properties and exhibits a sustained release of icariin. We studied whether icariin-loaded β-cyclodextrin sulfate can promote the endothelialization of TEBVs. The experimental results showed that icariin could significantly promote the proliferation and migration of endothelial progenitor cells; at the same time, icariin could promote the migration of rat vascular endothelial cells(RAVECs). Subsequently,we used an electrostatic force to modify the surface of the TEBVs with icariin-loaded β-cyclodextrin sulfate, and these vessels were implanted into the rat common carotid artery. After 3 months, micro-CT results showed that the TEBVs modified using icariin-loaded β-cyclodextrin sulfate had a greater patency rate. Scanning electron microscopy(SEM) and CD31 immunofluorescence results showed a better degree of endothelialization. Taken together, icariin-loaded β-cyclodextrin sulfate can achieve anticoagulation and rapid endothelialization of TEBVs to ensure their long-term patency. | Jingyuan Yang Keyu Wei Yeqin Wang Yanzhao Li Ning Ding Da Huo Tianran Wang Guanyuan Yang Mingcan Yang Tan Ju Wen Zeng Chuhong Zhu | 2018 | Science China(Life Sciences)2018，61，10： | 5 |
| 3 | Basic fibroblast growth factor protects against influenza A virus-induced acute lung injury by recruiting neutrophils显示文摘Influenza virus (IAV)infection is a major cause of severe respiratory illness that affects almost every country in the world.IAV infections result in respiratory illness and even acute lung injury and death,but the underlying mechanisms responsible for IAV pathogenesis have not yet been fully elucidated.In this study,the basic fibroblast growth factor 2 (FGF2)level was markedly increased in H1N1 virus-infected humans and mice.FGF2,which is predominately derived from epithelial cells,recruits and activates neutrophils via the FGFR2-PI3K-AKT-NFKB signaling pathway.FGF2 depletion or knockout exacerbated influenzaassociated disease by impairing neutrophil recruitment and activation.More importantly,administration of the recombinant FGF2 protein significantly aUeviated the severity of IAV-induced lung injury and promoted the survival of IAV-infected mice.Based on the results from experiments in which neutrophils were depleted and adoptively transferred,FGF2 protected mice against IAV , infection by recruiting neutrophils.Thus,FGF2 plays a critical role in preventing IAV-induced lung injury,and FGF2 is a promising potential therapeutic target during IAV infection. | Keyu Wang Chengcai Lai Tieling Li Cheng Wang Wei Wang Bing Ni Changqing Bai Shaogeng Zhang Lina Han Hongjing Gu Zhongpeng Zhao Yueqiang Duan Xiaolan Yang Li Xing Lingna Zhao Shanshan Zhou Min Xia Chengyu Jiang Xiliang Wang Penghui Yang | 2018 | Journal of Molecular Cell Biology2018，10，6： | 3 |
| 4 | A multiphase sodium vanadium phosphate cathode material for high-rate sodium-ion batteries显示文摘The unsatisfactory rate capability and poor cycling stability at high rate of sodium-ion batteries(SIBs) have impeded their practical applications. Herein, a Na_(3)V_(2)(PO_(4))_(3)/Na_(3)V_(3)(PO_(4))_(4) multiphase cathode materials for high-rate and long cycling SIBs was successfully synthesized by regulation the stoichiometric ratio of raw materials. The combined experiment and simulation results show that the multiphase materials consisted of NASICON structural phase Na3V2(PO4)3 and layered structure phase Na_(3)V_(3)(PO_(4))_(4), possess abundant phase boundaries. Electrochemical experiments demonstrate that the multiphase materials maintain a remarkable reversible capacity of 69.0 mA h g^(-1) even at an ultrahigh current density of 100 C with a high capacity retention of 81.25 % even after 10,000 cycles. Na_(3)V_(2)(PO_(4))_(3)/Na_(3)V_(3)(PO_(4))_(4) electrode exhibits a higher working voltage, superior rate capability and better cycling stability than Na_(3)V_(2)(PO_(4))_(3) electrode, which indicates that the introduction of second phase can be an effective strategy for the development of novel cathode materials for SIBs. | Chuan Wang Hai Long Lijiao Zhou Chao Shen Wei Tang Xiaodong Wang Bingbing Tian Le Shao Zhanyuan Tian Haijun Su Keyu Xie | 2021 | Journal of Materials Science & Technology2021，，7： | 1 |
| 5 | Highly ordered iron oxide nanotube arrays as electrodes for electrochemical energy storage显示文摘 | Keyu Xie Jie Li Yanqing Lai Wei Lu Zhi’an Zhang Yexiang Liu Limin Zhou Haitao Huang | 2011 | Electrochemistry Communications2011，，6： | 1 |
| 6 | Characteristics of sea ice kinematics from the marginal ice zone to the packed ice zone observed by buoys deployed during the 9th Chinese Arctic Expedition显示文摘Sea ice growth and consolidation play a significant role in heat and momentum exchange between the atmosphere and the ocean.However,few in situ observations of sea ice kinematics have been reported owing to difficulties of deployment of buoys in the marginal ice zone(MIZ).To investigate the characteristics of sea ice kinematics from MIZ to packed ice zone(PIZ),eight drifting buoys designed by Taiyuan University of Technology were deployed in the open water at the ice edge of the Canadian Basin.Sea ice near the buoy constantly increased as the buoy drifted,and the kinematics of the buoy changed as the buoy was frozen into the ice.This process can be determined using sea ice concentration,sea skin temperature,and drift speed of buoy together.Sea ice concentration data showed that buoys entered the PIZ in mid-October as the ice grew and consolidated around the buoys,with high amplitude,high frequency buoy motions almost ceasing.Our results confirmed that good correlation coefficient in monthly scale between buoy drift and the wind only happened in the ice zone.The correlation coefficient between buoys and wind was below 0.3 while the buoys were in open water.As buoys entered the ice zone,the buoy speed was normally distributed at wind speeds above 6 m/s.The buoy drifted mainly to the right of the wind within 45°at wind speeds above 8 m/s.During further consolidation of the ice in MIZ,the direct forcing on the ice through winds will be lessened.The correlation coefficient value increased to 0.9 in November,and gradually decreased to 0.7 in April. | Xiaomin Chang Longchun Ye Guangyu Zuo Jingyue Li Keyu Wei Yinke Dou | 2022 | Acta Oceanologica Sinica2022，41，7： | 1 |
| 7 | Three-dimensional characterization of micro-fractures in shale reservoir rocks显示文摘Fractures are crucial for unconventional hydrocarbon exploitation,but it is difficult to accurately observe the 3D spatial distribution characteristics of fractures.Microtomography(micro-CT)technology makes it possible to observe the 3D structures of fractures at micro-scale.In this study,micron-CT scanning is conducted on multiple mud-shale samples of source rocks in the Permian Lucaogou Formation,Junggar Basin.The Avizo^(®) software is applied to process and segment the micron-CT images,so as to obtain the 3D fracture structure model inside rock core.Therefore,the independently-developed CTSTA program is adopted to quantitatively describe the micro-fractures inside rock core,including fracture dimension,extension direction and extension scale.Meanwhile,this study summarizes the classification characteristics of fractures and their anisotropy.On this basis,the fractal dimensions of fractures can also be extracted.Previous studies show that the geometric features of fractures have self-similarity at large and small scales,which can be described by exponential laws;and the fractal dimension is a typical exponent.Through the quantitative description or characterization of 3D fractures at micro-scale,the distribution characteristics of fractures in large scales could be known. | Chao Qi Xiaoqi Wang Wei Wang Jie Liu Jincai Tuo Keyu Liu | 2018 | Petroleum Research2018，3，3： | 1 |
| 8 | Flexible,stretchable,and transparent InGaN/GaN multiple quantum wells/polyacrylamide hydrogel-based light emitting diodes显示文摘Visualization is a direct,efficient,and simple interface method to realize the interaction between human and machine,whereas the flexible display unit,as the major bottleneck,still deeply hinders the advances of wearable and virtual reality devices.To obtain flexible optoelectronic devices,one of the effective methods is to transfer a high-efficient and long-lifetime inorganic optoelectronic film from its rigid epitaxial substrate to a foreign flexible/soft substrate.Additionally,piezo-phototronic effect is a fundamental theory for guiding the design of flexible optoelectronic devices.Herein,we demonstrate a flexible,stretchable,and transparent InGaN/GaN multiple quantum wells(MQWs)/polyacrylamide(PAAM)hydrogel-based light emitting diode coupling with the piezo-phototronic effect.The quantum well energy band and integrated luminous intensity(increased by more than 31.3%)are significantly modulated by external mechanical stimuli in the device.Benefiting from the small Young's modulus of hydrogel and weak Van der Waals force,the composite film can endure an extreme tensile condition of about 21.1%stretching with negligible tensile strains transmitted to the InGaN/GaN MQWs.And the stable photoluminescence characteristics can be observed.Moreover,the hydrogen-bond adsorption and excellent transparency of the hydrogel substrate greatly facilitate the packaging and luminescence of the optoelectronic device.And thus,such a novel integration scheme of inorganic semiconductor materials and organic hydrogel materials would help to guide the robust stretchable optoelectronic devices,and show great potential in emerging wearable devices and virtual reality applications. | Jiwei Chen Jiangwen Wang Keyu Ji Bing Jiang Xiao Cui Wei Sha Bingjun Wang Xinhuan Dai Qilin Hua Lingyu Wan Weiguo Hu | 2022 | Nano Research2022，15，6： | 1 |
| 9 | Mesenchymal stromal cells alleviate acute respiratory distress syndrome through the cholinergic anti-inflammatory pathway显示文摘Mesenchymal stromal cells(MSCs)have been considered a promising alternative for treatment of acute respiratory distress syndrome(ARDS).However,there is significant heterogeneity in their therapeutic efficacy,largely owing to the incomplete understanding of the mechanisms underlying the therapeutic activities of MSCs.Here,we hypothesize that the cholinergic antiinflammatory pathway(CAP),which is recognized as a neuroimmunological pathway,may be involved in the therapeutic mechanisms by which MSCs mitigate ARDS.Using lipopolysaccharide(LPS)and bacterial lung inflammation models,we found that inflammatory cell infiltration and Evans blue leakage were reduced and that the expression levels of choline acetyltransferase(ChAT)and vesicular acetylcholine transporter(VAChT)in lung tissue were significantly increased 6 hours after MSC infusion.When the vagus nerve was blocked orα7 nicotinic acetylcholine(ACh)receptor(α7nAChR)-knockout mice were used,the therapeutic effects of MSCs were significantly reduced,suggesting that the CAP may play an important role in the effects of MSCs in ARDS treatment.Our results further showed that MSC-derived prostaglandin E2(PGE2)likely promoted ACh synthesis and release.Additionally,based on the efficacy of nAChR andα7nAChR agonists,we found that lobeline,the nicotinic cholinergic receptor excitation stimulant,may attenuate pulmonary inflammation and alleviate respiratory symptoms of ARDS patients in a clinical study(ChiCTR2100047403).In summary,we reveal a previously unrecognized MSC-mediated mechanism of CAP activation as the means by which MSCs alleviate ARDS-like syndrome,providing insight into the clinical translation of MSCs or CAP-related strategies for the treatment of patients with ARDS. | Xiaoran Zhang Xuxia Wei Yiwen Deng Xiaofeng Yuan Jiahao Shi Weijun Huang Jing Huang Xiaoyong Chen Shuwei Zheng Jieying Chen Keyu Chen Ruiming Xu Hongmiao Wang Weiqiang Li Shiyue Li Huimin Yi Andy Peng Xiang | 2022 | Signal Transduction and Targeted Therapy2022，7，10： | 1 |
| 10 | Visualization of enantioselective recognition and separation of chiral acids by aggregation-induced emission chiral diamine显示文摘Enantioselective recognition and separation are the most important issues in the fields of chemistry,pharmacy,agrochemical,and food science.Here,we developed two optically active diamines showing aggregation-induced emission(AIE)that can discriminate 5 kinds of chiral acids with high enantioselectivity.Especially,a very high fluorescence intensity ratio(IL/ID)of 281 for(±)-Dibenzoyl-D/L-tartaric acid was obtained through the collection of fluorescence change after interaction with chiral AIE-active diamine.By virtue of AIE property and intermolecular acidbase interaction,enantioselective separation was facilely realized by simple filtration of the precipitates formed by chiral AIE luminogen(AIEgen)and one enantiomer in the racemic solution.The chiral HPLC data indicated that the precipitates of AIEgen/chiral acid possessed 82%L-analyte(the enantiomeric excess value was assessed to be 64%ee).Therefore,this method can serve as a simple,convenient,and low-cost tool for chiral detection and separation. | Chunxuan Qi Keyue Wei Qingyang Li Yuemei Li Xiaolong Su Jun-Cheng Yang Jingjing Tian Pu Chen Hai-Tao Feng Ben Zhong Tang | 2023 | Aggregate2023，4，3： | 0 |
| 11 | Eye-around vibration haptics on VR immersion improvement显示文摘Due to the inherent shortcomings of the hardware,the immersion of visual interaction between the user and the virtual reality(VR)equipment is greatly reduced.In this paper,effects of eye-around vibration haptics on improving the VR immersion were studied.The vibration was generated by flexible vibrators whose performance was evaluated by a laser vibrometer.Fitting the vibrators on the human eye area at different positions and derived by different waveforms and frequencies of the input signal,the effects of vibration on the human vision and comfort of the users were verified.Then,with the selected input signals and fitting locations,different kinds of vibration were applied on the eye area cooperating with virtual reality images or videos to evaluate the changes of immersion.Research results provide references to the modeling of eye tactile feedback and the design of relevant tactile device in improving the VR immersion. | Tao ZENG Keyu WEI Yanlin YU Yi ZHAO | 2019 | Virtual Reality & Intelligent Hardware2019，1，2： | 0 |
| 12 | Extended pancreatoduodenectomy with portal vein and inferior vena cava resection and reconstruction combined with sorafenib for hepatoid carcinoma of the pancreas:a strategy of superextended surgery combined with targeted therapy显示文摘Hepatoid carcinoma of the pancreas(HCP)is an extremely rare pancreatic cancer resembling hepatocellular carcinoma,a type of liver cancer(1).Most reports have shown that it has an aggressive behavior and is associated with early metastasis.There is no standardized treatment for HCP due to its rarity,and the limited number of cases reported in the literature(2,3).However,treatment options for this type of rare cancer include surgery,chemotherapy,and radiation therapy,depending on the stage of the cancer.Nevertheless,the prognosis of HCP is poor. | Deling Wei Banghao Xu Hai Zhu Jilong Wang Zongrui Jin Weitao Chen Jianyong Zhang Zhujing Lan Keyu Huang Ling Zhang Tingting Lu Ni Fang Ya Guo Tao Peng Minhao Peng Zhang Wen | 2023 | Hepatobiliary Surgery and Nutrition2023，12，4： | 0 |
| 13 | Regulating electrodeposition behavior through enhanced mass transfer for stable lithium metal anodes显示文摘Electrode process kinetics is a key part that determines the morphology of metal electrodeposition.However,the liquid-phase mass transfer process and its effect on lithium(Li)metal electrodeposition are still poorly understood.Herein,the effect of mass transfer on the electrodeposition behavior of Li metal is explored.Experiments and COMSOL Multiphysics simulations reveal that the enhanced mass transfer,which is induced by ultrasonic wave,can homogenize the ion flow on the surface of electrode to obtain uniform Li nucleation.Meanwhile,the rapid mass transfer of Li^(+)provides sufficient cations around the germinated Li to avoid preferential growth of Li in a specific direction.Based on the simultaneous regulation of nucleation and growth behavior,a smooth and compact Li deposits can be achieved,which exhibit a small polarization voltage during repeated Li plating/striping and a considerably enhanced cyclability.This work enriches the fundamental understanding of Li electrodeposition without dendrite structure and affords fresh guidance to develop dendrite-free metal anodes for metal-based batteries. | Yuliang Gao Fahong Qiao Jingyuan You Chao Shen Hui Zhao Jinlei Gu Zengying Ren Keyu Xie Bingqing Wei | 2021 | Journal of Energy Chemistry2021，30，4： | 0 |
| 14 | Advances in the Application of Perovskite Materials显示文摘Nowadays, the soar of photovoltaic performance of perovskite solar cells has set off a fever in the study of metal halide perovskite materials. The excellent optoelectronic properties and defect tolerance feature allow metal halide perovskite to be employed in a wide variety of applications. This article provides a holistic review over the current progress and future prospects of metal halide perovskite materials in representative promising applications, including traditional optoelectronic devices(solar cells, light-emitting diodes, photodetectors, lasers), and cutting-edge technologies in terms of neuromorphic devices(artificial synapses and memristors) and pressure-induced emission. This review highlights the fundamentals, the current progress and the remaining challenges for each application, aiming to provide a comprehensive overview of the development status and a navigation of future research for metal halide perovskite materials and devices. | Lixiu Zhang Luyao Mei Kaiyang Wang Yinhua Lv Shuai Zhang Yaxiao Lian Xiaoke Liu Zhiwei Ma Guanjun Xiao Qiang Liu Shuaibo Zhai Shengli Zhang Gengling Liu Ligang Yuan Bingbing Guo Ziming Chen Keyu Wei Aqiang Liu Shizhong Yue Guangda Niu Xiyan Pan Jie Sun Yong Hua Wu‑Qiang Wu Dawei Di Baodan Zhao Jianjun Tian Zhijie Wang Yang Yang Liang Chu Mingjian Yuan Haibo Zeng Hin‑Lap Yip Keyou Yan Wentao Xu Lu Zhu Wenhua Zhang Guichuan Xing Feng Gao Liming Ding | 2023 | Nano-Micro Letters2023，15，10： | 0 |
| 15 | Full experimental determination of tunneling time with attosecond-scale streaking method显示文摘Tunneling is one of the most fundamental and ubiquitous processes in the quantum world.The question of how long a particle takes to tunnel through a potential barrier has sparked a long-standing debate since the early days of quantum mechanics.Here,we propose and demonstrate a novel scheme to accurately determine the tunneling time of an electron.In this scheme,a weak laser field is used to streak the tunneling current produced by a strong elliptically polarized laser field in an attoclock configuration,allowing us to retrieve the tunneling ionization time relative to the field maximum with a precision of a few attoseconds.This overcomes the difficulties in previous attoclock measurements wherein the Coulomb effect on the photoelectron momentum distribution has to be removed with theoretical models and it requires accurate information of the driving laser fields.We demonstrate that the tunneling time of an electron from an atom is close to zero within our experimental accuracy.Our study represents a straightforward approach toward attosecond time-resolved imaging of electron motion in atoms and molecules. | Miao Yu Kun Liu Min Li Jiaqing Yan Chuanpeng Cao Jia Tan Jintai Liang Keyu Guo Wei Cao Pengfei Lan Qingbin Zhang Yueming Zhou Peixiang Lu | 2022 | Light(Science & Applications)2022，11，8： | 0 |
| 16 | Understanding the Coffee ring Effect on Self-discharge Behavior of Printed micro-Supercapacitors显示文摘Printed micro-supercapacitor exhibits its flexibility in geometry design and integration,showing unprecedented potential in powering the internet of things and portable devices.However,the printing process brings undesired processing defects(e.g.,coffee ring effect),resulting in severe self-discharge of the printed micro-supercapacitors.The impact of such problems on device performance is poorly understood,limiting further development of microsupercapacitors.Herein,by analyzing the self-discharge behavior of fully printed micro-supercapacitors,the severe self-discharge problem is accelerated by the ohmic leakage caused by the coffee ring effect on an ultrathin polymer electrolyte.Based on this understanding,the coffee ring effect was successfully eradicated by introducing graphene oxide in the polymer electrolyte,achieving a decline of 99%in the self-discharge rate.Moreover,the micro-supercapacitors with uniformly printed polymer electrolyte present 7.64 F cm^(-3)volumetric capacitance(14.37 mF cm^(-2)areal capacitance),exhibiting about 50%increase compared to the one without graphene oxide addition.This work provides a new insight to understand the relationship between processing defects and device performance,which will help improve the performance and promote the application of printed micro-supercapacitors. | Jingzhi Hu Zhaohua Xu Kai Yuan Chao Shen Keyu Xie Bingqing Wei | 2022 | Energy & Environmental Materials2022，5，1： | 0 |
| 17 | Interactions between hydrocarbon-bearing fluids and calcite in fused silica capillary capsules and geological implications for deeply-buried hydrocarbon reservoirs显示文摘During the burial processes of deep/ultra-deep hydrocarbon reservoirs,the interactions between hydrocarbon-bearing fluids and reservoirs significantly affect the quality evolution of hydrocarbons and reservoirs;thus,this topic requires further investigation.In this study,the continuous evolution and the coupling mechanisms in various anhydrous and hydrous nC_(16)H_(34)-(water)-(calcite)systems in fused silica capillary capsules(FSCCs)were investigated using laser Raman spectroscopy,fluorescence color analysis,and fluorescence spectroscopy,and the mineral alterations were analyzed using scanning electron microscopy(SEM).The experimental results show that extensive organic-inorganic interactions occur in the systems if water is present,and different inorganic components have different effects on hydrocarbon degradation.Distilled water promotes freeradical thermal cracking and steps oxidation,forming more low-molecular-weight hydrocarbons,CO_(2),and organic acids(e.g.,acetic acids)but suppresses the free-radical cross-linking,generating less high-molecular-weight hydrocarbons.However,in the presence of CaCl_(2) water,the yields of hydrocarbon gases are lower than in the distilled water system because high concentrations of Ca ions inhibit the generation of free radicals.Calcites,which exhibit different surface reactivities in different fluid conditions,affect hydrocarbon degradation in different ways.In the anhydrous nC16H34-calcite system,calcites promote the generation of both hydrocarbon gases and high-molecular-weight hydrocarbons.In contrast,in the hydrous nC16H34-distilled(CaCl_(2))watercalcite system,calcites promote the generation of hydrocarbon gases and suppress the generation of high-molecular-weight hydrocarbons.Calcite also reacts with organic acids via surface reactions to form secondary pores.Therefore,except for the formation temperature and pressure,organic-inorganic interactions are controlled by multiple factors,such as the water saturation,water type,water salinity,and the mineral content,resulting in different evolutions of the hydrocarbon degradation and reservoir properties. | Zihao JIN Guanghui YUAN Yingchang CAO Keyu LIU Yanzhong WANG Jianye SUN Xiluo HAO Ling ZHOU Yihan WEI Shuqi WU | 2022 | Science China Earth Sciences2022，65，2： | 0 |
| 18 | Successive formation of secondary pores via feldspar dissolution in deeply buried feldspar-rich clastic reservoirs in typical petroliferous basins and its petroleum geological significance显示文摘Clastic rock reservoirs in petroliferous basins are generally rich in feldspars. Feldspar dissolution has developed widely in clastic reservoirs, and the resulting secondary pores are crucial in deeply buried reservoirs. Based on a study of the diagenesis of clastic reservoirs in the Bohai Bay Basin, Tarim Basin, and Pearl River Mouth Basin and physical and numerical simulation experiments of fluid-rock interactions, this paper proposed a successive formation model of secondary pores via feldspar dissolution in deeply buried clastic reservoirs, considering the global research progresses in feldspar dissolution in clastic rocks. Feldspar dissolution can occur from shallow open systems to deep-ultra deep closed systems in petroliferous basins, resulting in the successive formation of secondary pores at different diagenetic stages. The successive mechanism includes three aspects. The first aspect is the succession of corrosive fluids that dissolve minerals. Meteoric freshwater dominates at the Earth’s surface and the early diagenetic A stage. Subsequently, organic acids and COformed via kerogen maturation dominate at the early diagenetic B stage to the middle diagenetic stage. COand organic acids formed via hydrocarbon oxidation in hydrocarbon reservoirs dominate at the middle diagenetic B stage to the late diagenetic stage. The second aspect is the successive formation processes of secondary pores via feldspar dissolution. Large-scale feldspar secondary pores identified in deep reservoirs include secondary pores formed at shallow-medium depths that are subsequently preserved into deep layers, as well as secondary pores formed at deep depths. Existing secondary pores in deeply buried reservoirs are the superposition of successively feldspar dissolution caused by different acids at different stages. The third aspect is a successive change in the feldspar alteration pathways and porosity enhancement/preservation effect. Open to semi-open diagenetic systems are developed from the Earth’s surface to the early diagenetic stage, and feldspar dissolution forms enhanced secondary pores. Nearly closed to closed diagenetic systems develop in the middle to late diagenetic stages, and feldspar dissolution forms redistributional secondary pores. The associated cementation causes compression resistance of the rock, which is favorable for the preservation of secondary pores in deep layers. These new insights extend the formation window of secondary pores in petroliferous basins from the traditional acid-oil generation window to a high-temperature gas generation window after hydrocarbon charging. The proposed model explains the genesis of deep-ultra deep high-quality reservoirs with low-permeability, medium-porosity and dominating feldspar secondary pores, which is significant for hydrocarbon exploration in deep to ultra-deep layers. | Yingchang CAO Guanghui YUAN Yanzhong WANG Nianmin ZAN Zihao JIN Keyu LIU Kelai XI Yihan WEI Peipei SUN | 2022 | Science China Earth Sciences2022，65，9： | 0 |
| 19 | Preparation and characterization of polymer-clay nanocomposite films显示文摘Polymer/clay nanocomposite films were prepared by means of electrodeposition of aqueous suspension including cathodic electrophoretic acrylic resin (CEAR) and Na+-montmorillonite (NMMT). Studies of XRD,SEM and TEM indicated well-dispersed NMMT platelets in the films prepared. The ideal dispersity achieved was thought to be the result of aqueous compatibility between CEAR molecules and NMMT platelets and the result of the water-involved process as well. The modulus and strength of the polymer/clay nanocomposite coatings tested by tensile testing and nano-indentation were effectively improved compared to those of the virgin CEAR film. In addition,the adhesion strength,flexibility and water-resistance represented by Chinese national standard (GB) kept the best grades. | CHEN KeYu WANG ChangAn HUANG Yong LIN Wei | 2009 | Science China Chemistry2009，52，12： | 0 |
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