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23篇 您的检索式:作者名="Junmin Yan"
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1Consensus on the application of negative pressure wound therapy of diabetic foot wounds显示文摘Because China is becoming an aging society,the incidence of diabetes and diabetic foot have been increasing.Diabetic foot has become one of the main health-related killers due to its high disability and mortality rates.Negative pressure wound therapy(NPWT)is one of the most effective techniques for the treatment of diabetic foot wounds and great progress,both in terms of research and its clinical application,has been made in the last 20 years of its development.However,due to the complex pathogenesis and management of diabetic foot,irregular application of NPWT often leads to complications,such as infection,bleeding and necrosis,that seriously affect its treatment outcomes.In 2020,under the leadership of Burns,Trauma and Tissue Repair Committee of the Cross-Straits Medicine Exchange Association,the writing group for‘Consensus on the application of negative pressure wound therapy of diabetic foot wounds’was established with the participation of scholars from the specialized areas of burns,endocrinology,vascular surgery,orthopedics and wound repair.Drawing on evidence-based practice suggested by the latest clinical research,this consensus proposes the best clinical practice guidelines for the application and prognostic evaluation of NPWT for diabetic foot.The consensus aims to support the formation of standardized treatment schemes that clinicians can refer to when treating cases of diabetic foot.Shizhao Ji Xiaobin Liu Jie Huang Junmin Bao Zhaohong Chen Chunmao Han Daifeng Hao Jingsong Hong Dahai Hu Yufeng Jiang Shang Ju Hongye Li Zongyu Li Guangping Liang Yan Liu Gaoxing Luo Guozhong Lv Xingwu Ran Zhongmin Shi Juyu Tang Aiping Wang Guangyi Wang Jiangning Wang Xin Wang Bing Wen Jun Wu Hailin Xu Maojin Xu Xiaofei Ye Liangxi Yuan Yi Zhang Shichu Xiao Zhaofan Xia 2021Burns & Trauma2021,9,1:17
2Iron-chelated hydrogel-derived bifunctional oxygen electrocatalyst for high-performance rechargeable Zn-air batteries显示文摘Fanlu Meng Haixia Zhong Junmin Yan Xinbo Zhang 2017Nano Research2017,10,12:4
3Characterizing optical dipole trap via fluorescence of trapped cesium atoms显示文摘Optical dipole trap (ODT) is becoming an important tool of manipulating neu- tral atoms. In this paper ODT is realized with a far-off resonant laser beam strongly fo- cused in the magneto-optical trap (MOT) of cesium atoms. The light shift is measured by simply monitoring the fluorescence of the atoms in the magneto-optical trap and the opti- cal dipole trap simultaneously. The advantages of our experimental scheme are discussed, and the effect of the beam waist and power on the potential of dipole trap as well as heating rate is analyzed.LIU Tao GENG Tao YAN Shubin LI Gang ZHANG Jing WANG Junmin PENG Kunchi ZHANG Tiancai 2006Science China(Physics,Mechanics & Astronomy)2006,49,3:4
4Chromobox homolog 4 overexpression inhibits TNF-α-induced matrix catabolism and senescence by suppressing activation of NF-κB signaling pathway in nucleus pulposus cells显示文摘Intervertebral disc degeneration(IDD)is featured as enhanced catabolism of extracellular matrix(ECM)in the nucleus pulposus(NP),in which tumor necrosis factor-alpha(TNF-α)-related cell senescence is involved.Chromobox homolog protein 4(CBX4)exhibits anti-inflammatory effects and shows promising therapeutic potential.Thus,in the present study,we explore the role of CBX4 in IDD.Immunohistochemistry staining reveals that CBX4 expression is decreased in severe degenerative NP tissues compared to mild degenerative tissues,and real-time PCR and western blot analysis results show that CBX4 expression is downregulated under TNF-αstimulation in NP cells.siRNA and adenoviruses are used to knockdown or overexpress CBX4,respectively.The results demonstrate that CBX4 knockdown augments the catabolism of ECM in human NP cells,while CBX4 overexpression in rat NP cells restores the ECM degradation induced by TNF-α,as illustrated by immunofluorescence and western blot analysis.In addition,transcriptome sequencing results reveal the regulatory effect of CBX4 on the cell cycle,and further western blot analysis and senescence-associatedβ-galactosidase staining assay indicate that CBX4 overexpression alleviates cell senescence in the presence of TNF-α.Moreover,the phosphorylation of p65,which indicates the activation of NF-κB signaling,is measured by western blot analysis and immunofluorescence assay,and the results reveal that CBX4 overexpression reduces the TNF-α-induced increase in the p-p65/p65 ratio.In addition,the effect of CBX4 overexpression in NP cells is suppressed by NF-κB agonist.In summary,our results indicate that CBX4 overexpression can suppress TNF-α-induced matrix catabolism and cell senescence in the NP by inhibiting NF-κB activation.This study may provide new approaches for preventing and treating IDD.Yangyang Zhang Shuangxing Li Junmin Hong Jiansen Yan Zhengqi Huang Jiajun Wu Zhihuai Deng Tianyu Qin Kang Xu Wei Ye 2022Acta Biochimica et Biophysica Sinica2022,54,7:2
5Hollow Ni-SiO2 nanosphere-catalyzed hydrolytic dehydrogenation of ammonia borane for chemical hydrogen storage 显示文摘Umegaki T Yan Junmin Zhang Xingbo 2009J Power Sources2009,191,2:1
6显示文摘Yan Junmin Zhang Xinbo Han Song 2009Journal of Power Sources2009,194,1:1
7Identification of in-vivo induced genes of Streptococcus suis serotype 2 specially expressed in infected human显示文摘Shu Li Jie Song Hui Huang Wei Chen Ming Li Yan Zhao Yanguang Cong Junmin Zhu Xiancai Rao Xiaomei Hu Fuquan Hu 2013Microbial Pathogenesis2013,,:1
8Design and Evaluation on Electric Dif- ferentials for Overactuated Electric Ground Vehicles with Four In- dependent In-Wheel Motors显示文摘Chen Yan Wang Junmin 2012IEEE Transactions on Vehicular Technology2012,61,4:1
9Hybrid Electric Vehicle Model Predictive Control Torque-Split Strategy Incorpora- ting Engine Transient Characteristics 显示文摘Yan Fengjun Wang Junmin Huang Kaisheng 2012IEEE Transactions on Vehicular Technology2012,61,16:1
10Design and evaluation on electric differentials for overactuated electric ground vehicles with four independent in-wheel motors显示文摘CHEN Yan WANG Junmin 2012IEEE Transactions on Vehicular Technology2012,61,4:1
11Guidelines for the diagnosis and treatment of acute pancreatitis in China (2021)显示文摘Acute pancreatitis(AP)is a common acute abdominal condition of the digestive system.In recent years,treatment concepts,methods,and strategies for the diagnosis of AP have advanced,and this has played an important role in promoting the standardization of AP diagnosis and treatment and improving the treatment quality of AP patients.On the basis of previous guidelines and expert consensus,this guideline adopts an evidence-based,problem-based expression;synthesizes important clinical research data at home and abroad in the most recent 5 years;and forms 29 recommendations through multidisciplinary expert discussion,including diagnosis,treatment,and follow-up.It is expected to provide evidence support for the treatment of AP in the clinical setting in China.Fei Li Shouwang Cai Feng Cao Rufu Chen Deliang Fu Chunlin Ge Chunyi Hao Jihui Hao Heguang Huang Zhixiang Jian Gang Jin Ang Li Haimin Li Shengping Li Weiqin Li Yixiong Li Tingbo Liang Xubao Liu Wenhui Lou Yi Miao Yiping Mou Chenghong Peng Renyi Qin Chenghao Shao Bei Sun Guang Tan Xiaodong Tian Huaizhi Wang Lei Wang Wei Wang Weilin Wang Junmin Wei Heshui Wu Wenming Wu Zheng Wu Changqing Yan Yinmo Yang Xiaoyu Yin Xianjun Yu Chunhui Yuan Taiping Zhang Yupei Zhao on behalf of the Chinese Pancreatic Surgery Association 2021Journal of Pancreatology2021,4,2:1
12Increased leucine-rich repeats and immunoglobulin- like domains 1 expression enhances chemosensitivity in glioma显示文摘Leucine-rich repeats and immunoglobulin-like domains 1 (LRIG1) is an anti-oncogene. LRIG1 is correlated with Bcl-2 in ependymomas. Decreased Bcl-2 and manganese superoxide dismutase expression can improve the chemosensitivity of glioma. In the present study, a tissue microarray of human brain astrocytomas was constructed. To investigate the relationship of LRIG1 with Bcl-2 and manganese superoxide dismutase, LRIG1, Bcl-2 and manganese su-peroxide dismutase expression in our tissue microarray was determined using immunohisto-chemistry. In addition, we constructed the LRIG1-U251 cell line, and its responses to doxoru-bicin and temozolomide were detected using the MTT assay. Results showed that LRIG1 ex-pression was significantly negatively correlated with Bcl-2 and manganese superoxide dismu-tase expression in glioma. Also, proliferation of LRIG1-U251 cells exposed to doxorubicin or temozolomide was significantly inhibited, i.e. in the LRIG1-U251 cell line, the chemosensitivity to doxorubicin and temozolomide was increased. This indicates that increased LRIG1 expres-sion produces a chemosensitivity in glioma.Baohui Liu Qianxue Chen Daofeng Tian Licluan Wu Junmin Wang Qiang Cai Heng Shen Baowei Ji Long Wang Shenqi Zhang Dong Ruan Xiaonan Zhu Zhentao Guo Huimin Dong Mingmin Yan 2011Neural Regeneration Research2011,6,32:1
13Development and performance characterization of an electric ground vehicle with independently actuated in-wheel motors显示文摘Rongrong Wang Yan Chen Daiwei Feng Xiaoyu Huang Junmin Wang 2010Journal of Power Sources2010,,:1
14Identification of molecular markers linked to rice bacterial blight resistance genes from Oryza meyeriana显示文摘Y73 is a progeny of asymmetric somatic hybridization between Oryza sativa cv.Dalixiang and the wild rice species Oryza meyeriana.Inoculation with a range of strains of Xanthomonas oryzae pv.oryzae showed that Y73 had inherited a high level of resistance to rice bacterial blight(BB)from its wild parent.An F2 population of 7125 individuals was constructed from the cross between Y73 and a BB-susceptible cultivar IR24.After testing 615 SSR and STS markers covering the 12 rice chromosomes,186 markers were selected that showed polymorphism between Y73 and IR24.Molecular markers linked to the BB resistance genes in Y73 were scanned using the F2 population and the polymorphic markers.The SSR marker RM128 on chromosome 1,the STS marker R03D159 on chromosome 3 and the STS marker R05D104 on chromosome 5 were found to be linked to the rice BB resistance genes in Y73.Jing WANG Chen CHENG Yanru ZHOU Yong YANG Qiong MEI Junmin LI Ye CHENG Chengqi YAN Jianping CHEN 2015Frontiers of Agricultural Science and Engineering2015,2,3:1
15Adaptive Energy-Efficient Control Allocation for Planar Motion Control of Over-Actuated Electric Ground Vehicle 显示文摘CHEN Yan WANG Junmin 2014IEEE Transactions on Control Systems Technology2014,22,4:1
16Etoposide,dexamethasone,and pegaspargase with sandwiched radiotherapy in early-stage natural killer/T-cell lymphoma:A randomized phase III study显示文摘Methotrexate,etoposide,dexamethasone,and pegaspargase(MESA)with sandwiched radiotherapy is known to be effective for early-stage extranodal natural killer/T-cell lymphoma,nasal type(NKTCL).We explored the efficacy and safety of reduced-intensity,non-intravenous etoposide,dexamethasone,and pegaspargase(ESA)with sandwiched radiotherapy.This multicenter,randomized,phase III trial enrolled patients aged between 14 and 70 years with newly diagnosed early-stage nasal NKTCL from 27 centers in China.Patients were randomly assigned(1:1)to receive ESA(pegaspargase 2,500 IU/m^(2)intramuscularly on day 1,etoposide 200 mg orally,and dexamethasone 40 mg orally on days 2–4)or MESA(methotrexate 1 g/m^(2)intravenously on day 1,etoposide 200 mg orally,and dexamethasone 40 mg orally on days 2–4,and pegaspargase 2,500 IU/m^(2)intramuscularly on day 5)regimen(four cycles),combined with sandwiched radiotherapy.Huijuan Zhong Shu Cheng Xi Zhang Bing Xu Jiayi Chen Xufeng Jiang Jie Xiong Yu Hu Guohui Cui Juying Wei Wenbin Qian Xiaobing Huang Ming Hou Feng Yan Xin Wang Yongping Song Jianda Hu Yuanhua Liu Xuejun Ma Fei Li Chongyang Wu Junmin Chen Li Yu Ou Bai Jingyan Xu Zunmin Zhu Li Liu Xin Zhou Li Huang Yin Tong Ting Niu Depei Wu Hao Zhang Chaofu Wang Binshen Ouyang Hongmei Yi Qi Song Gang Cai Biao Li Jia Liu Zhifeng Li Rong Xiao Luqun Wang Yujie Jiang Yanyan Liu Xiaoyun Zheng Pengpeng Xu Hengye Huang Li Wang Saijuan Chen Weili Zhao 2023The Innovation2023,4,3:0
17A review of the etched terminal structure of a 4H-SiC PiN diode显示文摘The comparison of domestic and foreign studies has been utilized to extensively employ junction termination extension(JTE)structures for power devices.However,achieving a gradual doping concentration change in the lateral direction is difficult for SiC devices since the diffusion constants of the implanted aluminum ions in SiC are much less than silicon.Many previously reported studies adopted many new structures to solve this problem.Additionally,the JTE structure is strongly sensitive to the ion implantation dose.Thus,GA-JTE,double-zone etched JTE structures,and SM-JTE with modulation spacing were reported to overcome the above shortcomings of the JTE structure and effectively increase the breakdown voltage.They provided a theoretical basis for fabricating terminal structures of 4H-SiC PiN diodes.This paper summarized the effects of different terminal structures on the electrical properties of SiC devices at home and abroad.Presently,the continuous development and breakthrough of terminal technology have significantly improved the breakdown voltage and terminal efficiency of 4H-SiC PiN power diodes.Hang Zhou Jingrong Yan Jialin Li Huan Ge Tao Zhu Bingke Zhang Shucheng Chang Junmin Sun Xue Bai Xiaoguang Wei Fei Yang 2023Journal of Semiconductors2023,44,11:0
18Preparation of Square and Labyrinth-Like TiO_2 Particles for Photo-Degradation of Organic Pollutants显示文摘Square and labyrinth-like titanium dioxide particles were successfully synthesized by a simple hydrothermal method with assistant of halloysite nanotubes. The morphology and microstructure of as-prepared photo-catalysts were characterized by X-ray powder diffraction, scanning electron microscopy, transmission electron microscopy, and X-ray photoelectron spectroscopy. The photo-catalytic activity of as-prepared catalysts was evaluated by degradation of organic pollutants(Rhodamine B, methylene blue and methanol) under UV light irradiation.Yongjie Yan Shasha Zhang Guohua Jiang Xia Li Zhen Wei Wenxing Chen Junmin Wan 2014Acta Metallurgica Sinica(English Letters)2014,27,6:0
19Consensus of clinical diagnosis and treatment for non-functional pancreatic neuroendocrine neoplasms with diameter<2 cm显示文摘In clinical practice,pancreatic neuroendocrine neoplasms(pNENs)with a diameter smaller than 2 cm are commonly referred to as small pNENs.Due to their generally favorable biological characteristics,the diagnosis and treatment of small pNENs differ from other pNENs and are somewhat controversial.In response to this,the Chinese Pancreatic Surgery Association,Chinese Society of Surgery,Chinese Medical Association have developed a consensus on the diagnosis and treatment of small pNENs,which is based on evidence-based medicine and expert opinions.This consensus covers various topics,including concepts,disease assessment,treatment selection,follow-up,and other relevant aspects.Wu Wenming Cai Shouwang Chen Rufu Fu Deliang Ge Chunlin Hao Chunyi Hao Jihui Huang Heguang Jian Zhixiang Jin Gang Li Fei Li Haimin Li Shengping Li Weiqin LiYixiong Liang Tingbo Liu Xubao Lou Wenhui Miao Yi Mou Yiping Peng Chenghong Qin Renyi Shao Chenghao Sun Bei Tan Guang Wang Huaizhi Wang Lei Wang Wei Wang Weilin Wei Junmin Wu Heshui Wu Zheng Yan Changqing Yang Yinmo Yin Xiaoyu Yu Xianjun Yuan Chunhui Zhao Yupei 2023Journal of Pancreatology2023,6,3:0
20Efficient nitrate-to-ammonia transformation through a direct eight-electron reduction显示文摘Ammonia(NH3),as one of the most necessary chemical materials,is mainly produced via the Haber-Bosch process from hydrogen(H2)and nitrogen(N2),which requires harsh synthesis conditions and aggravates energy consumption and greenhouse effect[1].As an alternative,electrocatalytic N2 reduction to NH3 has evolved for years.However,most of electrocatalysts are confined to poor NH3 synthesis efficiency restricted by the strong N≡N triple bonds,the competition of hydrogen evolution reaction(HER),and limited N2 solubility in H2O[2].Jiaxin Yao Junmin Yan 2020Science China Chemistry2020,63,12:0
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