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| 1 | Characterization of Nestin-positive stem Leydig cells as a potential source for the treatment of testicular Leydig cell dysfunction显示文摘 | Mei Hua Jiang Bing Cai Ying Tuo Jiancheng Wang Zhi Jun Zang Xiang'an Tu Yong Gao Zhijian Su Weiqiang Li Guilan Li Min Zhang Jianwei Jiao Zi Wan Chunhua Deng Bruce T Lahn Andy Peng Xiang | 2014 | Cell Research2014,24,12: | 14 |
| 2 | 食管和贲门癌前病变癌基因c-erbB_2、c-myc和cyclin D_1的表达研究显示文摘为了解食管和贲门癌变的分子生物学发生基础,采用免疫组化技术测定人食管和贲门正常上皮和癌前病变组织的癌基因蛋白c-erbB2,c-myc和cyclinD1的表达状况。研究对象来自食管癌高发区河南辉县。结果:在食管,未观察到c-erbB2的阳性表达(0/54);而c-myc和cyclinD1的阳性表达率分别为25%(6/24)和82%(94/115)。贲门上皮c-erbB2和c-myc的阳性表达率分别为73%(16/26)和78%(31/40),均明显高于食管组织的表达。贲门组织cyclinD1的阳性表达率为78%(31/40),但是,随着贲门上皮病变加重,cyclinD1的阳性表达率呈现下降趋势。提示同一地区食管和贲门癌前病变发生存在不同的分子学改变;食管和贲门癌变的不同阶段可能由多种癌基因参与作用;c-erbB2可能是贲门癌变的重要分子学变化。 | 王立东 周琦 李永欣 邢莹 刘保池 裘宋良 Susan Goldstein Stephenie T Shi Jun Y.Hong Chung S.Yang | 1995 | 河南医科大学学报1995,30,2: | 7 |
| 3 | 2型糖尿病患者采用血管紧张素转换酶抑制剂治疗后血清肌酐急性升高及其继续治疗对主要临床结局的影响显示文摘血管紧张素转换酶抑制剂开始治疗后血清肌酐急性升高≥30%时推荐停药。但血清肌酐升高后继续服药或停药对主要临床结局的长期影响仍不明确。在ADVANCE(糖尿病与血管疾病行动:培哚普利-吲达帕胺与达美康缓释片对照评估)试验中,11 140例糖尿病患者在6周活性导入期后随机采用培哚普利-吲达帕胺或安慰剂治疗。 | Ohkuma T Jun M Rodgers A Cooper ME Glasziou P Hamet P Harrap S Mancia G Marre M Neal B Perkovic V Poulter N Williams B Zoungas S Chalmers J Woodward M 赵狄 练桂丽 | 2019 | 中华高血压杂志2019,27,1: | 6 |
| 4 | Targeted next‐generation sequencing of cancer genes dissects the molecular profiles of intraductal papillary neoplasms of the pancreas显示文摘 | Eliana Amato Marco dal Molin Andrea Mafficini Jun Yu Giuseppe Malleo Borislav Rusev Matteo Fassan Davide Antonello Yoshihiko Sadakari Paola Castelli Giuseppe Zamboni Anirban Maitra Roberto Salvia Ralph H Hruban Claudio Bassi Paola Capelli Rita T Lawlor Mi | 2014 | J. Pathol2014,,3: | 2 |
| 5 | Prostate volume does not provide additional predictive value to prostate health index for prostate cancer or clinically significant prostate cancer:results from a multicenter study in China显示文摘To evaluate whether prostate volume(PV)would provide additional predictive utility to the prostate health index(phi)for predicting prostate cancer(PCa)or clinically significant prostate cancer,we designed a prospective,observational multicenter study in two prostate biopsy cohorts.Cohort 1 included 595 patients from three medical centers from 2012 to 2013,and Cohort 2 included 1025 patients from four medical centers from 2013 to 2014.Area under the receiver operating characteristic curves(AUC)and logistic regression models were used to evaluate the predictive performance of PV-based derivatives and models.Linear regression analysis showed that both total prostate-specific antigen(tPSA)and free PSA(fPSA)were significantly correlated with PV(all P<0.05).[-2]proPSA(p2PSA)was significantly correlated with PV in Cohort 2(P<0.001)but not in Cohort 1(P=0.309),while no significant association was observed between phi and PV.When combining phi with PV,phi density(PHID)and another phi derivative(PHIV,calculated as phi/PV°5)did not outperform phi for predicting PCa or clinically significant PCa in either Cohort 1 or Cohort 2.Logistic regression analysis also showed that phi and PV were independent predictors for both PCa and clinically significant PCa(all P<0.05);however,PV did not provide additional predictive value to phi when combining these derivatives in a regression model(all models vs phi were not statistically significant,all P>0.05).In conclusion,PV-based derivatives(both PHIV and PHID)and models incorporating PV did not improve the predictive abilities of phi for either PCa or clinically significant PCa. | Da Huang Yi-Shuo Wu Ding-Wei Ye Jun Qi Fang Liu Brian T Helfand Siqun L Zheng Qiang Ding Dan-Feng Xu Rong Na Jian-Feng Xu Ying-Hao Sun | 2020 | Asian Journal of Andrology2020,22,5: | 2 |
| 6 | Milk Basic Protein (MBP) increases radial bone mineral density in healthy adult women显示文摘 | Jun Ichi Y Seiicihiro A Yasuhiro T | 2002 | Biosci Biotechnol Biochem2002,66,3: | 1 |
| 7 | Self- healing in networks with multiple reliability classes 显示文摘 | Tokuhiro K Jun T | 2001 | Electron Comm Jpn Part I2001,84,7: | 1 |
| 8 | Persistent problemsof access to appropriate, affordable TB services in rural China: experiences of different socio-economic groups 显示文摘 | Zhang T Tang S Jun G Whitehead M | 2007 | BMC Pub- lic Health2007,7,: | 1 |
| 9 | Spatio-temporal spectral analysis by eigenstructure methods显示文摘 | WAX M JUN S T KAILATH T | 1984 | IEEE Trans-SP1984,32,4: | 1 |
| 10 | Media Access Control for Ethernet Passive Optical Networks: An Overview显示文摘 | Zheng Jun Mouftah H T | 2005 | Communications Magazine2005,43,2: | 1 |
| 11 | Hybrid linear programming based decoding algorithm for LDPC codes 显示文摘 | Ngatched T M N Alfa A S Jun Cai | 2011 | IEEE Transactions on Wireless Communcations2011,59,3: | 1 |
| 12 | Consumer evaluations of multiple versus single price change显示文摘 | Mazumdar T Jun S Y | 1993 | Journal of Consumer Research1993,20,3: | 1 |
| 13 | Inhibition of glutaminase selectively suppresses the growth of primary acute myeloid leukemia cells with IDH mutations显示文摘 | Emadi A Jun SA Tsukamoto T | 2014 | Exp Hematol2014,42,4: | 1 |
| 14 | Urinary TWEAK level as a marker of lupus nephritis activity in 46 cases显示文摘 | Xuejing Z Jiazhen T Jun L | 2012 | J Biomed Biotechnol2012,,35: | 1 |
| 15 | Are endoscopic grading and scoringsystems in inflammatory bowel disease the same显示文摘 | JUN S HUA R Z LU T J | 2008 | Saudi Med J2008,29,10: | 1 |
| 16 | Effects of chromium on seed germination,root elongation and coleoptile growth in six pulses显示文摘 | LING T CUANGHUA Z JUN R | 2009 | Int J Environ Sci Tech2009,6,4: | 1 |
| 17 | Studies on the inheritance of grain size and shape in rice显示文摘 | Jun B T | 1985 | Crop1985,,2: | 1 |
| 18 | NO/cyclic GMP pathway mediates the relaxation of feline lower oesophageal sphincter显示文摘 | JUN C H LEE T S SOHN U D | 2003 | Auton Autacoid Pharmacol2003,23,3: | 1 |
| 19 | Influence of casting con- ditions on molten steel flow in continuous casting mold at high speed casting of slabs显示文摘 | Toshio T Jun K Mikio S | 1993 | Tetsu-to-Hagane1993,79,5: | 1 |
| 20 | Optimization of pigment production of Monascus purpureus P-57 in liquid culture显示文摘 | DUCK P C JUN J H YU T S | 2005 | Korean Society for Biotechnology and Bioengineering2005,20,1: | 1 |