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| 1 | Management of ampullary neoplasms: A tailored approach between endoscopy and surgery显示文摘Ampullary neoplasms,although rare,present distinctive clinical and pathological features from other neoplastic lesions of the periampullary region.No specific guidelines about their management are available,and they are often assimilated either to biliary tract or to pancreatic carcinomas.Due to their location,they tend to become symptomatic at an earlier stage compared to pancreatic malignancies.This behaviour results in a higher resectability rate at diagnosis.From a pathological point of view they arise in a zone of transition between two different epithelia,and,according to their origin,may be divided into pancreatobiliary or intestinal type.This classification has a substantial impact on prognosis.In most cases,pancreaticoduodenectomy represents the treatment of choice when there is an overt or highly suspicious malignant behaviour.The rate of potentially curative resection is as high as 90% and in high-volume centres an acceptable rate of complications is reported.In selected situations less invasive approaches,such as ampullectomy,have been advocated,although there are some concerns mainly because of a higher recurrence rate associated with limited resections for invasive carcinomas.Importantly,these methods have the drawback of not including an appropriate lymphadenectomy,while nodal involvement has been shown to be frequently present also in apparently lowrisk carcinomas.Endoscopic ampullectomy is now the procedure of choice in case of low up to high-grade dysplasia providing a proper assessment of the T status by endoscopic ultrasound.In the present paper the evidence currently available is reviewed,with the aim of offering an updated framework for diagnosis and management of this specific type of disease. | Francesca Panzeri Stefano Crippa Paola Castelli Francesca Aleotti Alessandro Pucci Stefano Partelli Giuseppe Zamboni Massimo Falconi | 2015 | World Journal of Gastroenterology2015，21，26： | 6 |
| 2 | A Procedure for the Design of Novel Assisting Devices for the Sit-to-Stand显示文摘 | Pierluigi Rea Erika Ottaviano Gianni Castelli | 2013 | Journal of Bionic Engineering2013，10，4： | 4 |
| 3 | Precancerous lesions of the pancreas显示文摘 | Giuseppe Zamboni Kenichi Hirabayashi Paola Castelli Anne Marie Lennon | 2013 | Best Practice & Research Clinical Gastroenterology2013，，2： | 3 |
| 4 | Culture-Based Selection Therapy for Patients Who Did Not Respond to Previous Treatment for Helicobacter pylori Infection显示文摘 | Giulia Fiorini Nimish Vakil Angelo Zullo Ilaria M. Saracino Valentina Castelli Chiara Ricci Cristina Zaccaro Luigi Gatta Dino Vaira | 2012 | Clinical Gastroenterology and Hepatology2012，，： | 3 |
| 5 | One Step on the Smart Grid Path: Load and Generation Coordination in a Virtual Power System显示文摘 | E. Cagno F. Castelli Dezza M. Delfanti M. Merlo A. Trianni | 2011 | Journal of Energy and Power Engineering2011，5，3： | 2 |
| 6 | Phase Contrast Micro-Computed Tomography of Biological Sample at SSRF显示文摘In line X-ray phase contrast micro-computed tomography(IL-XPCT),which can be implemented at third generation synchrotron radiation sources or by using a micro-focus X-ray tube,is a powerful technique for non-destructive,high-resolution investigations of a broad variety of materials.At the Shanghai Synchrotron Radiation Facility(SSRF),the X-ray Imaging and Biomedical Applications Beamline was built and started regular user operation in May 2009.Both qualitative(without phase retrieval) and quantitative(with phase retrieval) three-dimensional IL-XPCT experimental techniques have been established at the beamline.IL-XPCT experiments of a test sample(plastic pipes) used to evaluate the technique,and of a biological sample(locust) at the beamline are reported.Two series of images,qualitative and quantitative,including tomographic slices and three-dimensional rendering images were obtained.In qualitative images,there is a strong edge-enhancement which leads to very clear sample contours,while in quantitative images,the edge-enhancement fades but quantitative measurement of sample's phase information could be achieved.The experiments demonstrate that the combination of qualitative and quantitative images is useful for biological sample studies. | 陈荣昌 谢红兰 Luigi Rigon 杜国浩 Edoardo Castelli 肖体乔 | 2010 | Tsinghua Science and Technology2010，15，1： | 2 |
| 7 | Targeted next‐generation sequencing of cancer genes dissects the molecular profiles of intraductal papillary neoplasms of the pancreas显示文摘 | Eliana Amato Marco dal Molin Andrea Mafficini Jun Yu Giuseppe Malleo Borislav Rusev Matteo Fassan Davide Antonello Yoshihiko Sadakari Paola Castelli Giuseppe Zamboni Anirban Maitra Roberto Salvia Ralph H Hruban Claudio Bassi Paola Capelli Rita T Lawlor Mi | 2014 | J. Pathol2014，，3： | 2 |
| 8 | Characterisation of a microwave induced plasma torch for glass surface modification显示文摘Microwave induced plasma torches find wide applications in material and chemical analysis.Investigation of a coaxial electrode microwave induced plasma(CE–MIP)torch is conducted in this study,making it available for glass surface modification and polishing.A dedicated nozzle is designed to inject secondary gases into the main plasma jet.This study details the adaptation of a characterisation process for CE–MIP technology.Microwave spectrum analysis is used to create a polar plot of the microwave energy being emitted from the coaxial electrode,where the microwave energy couples with the gas to generate the plasma jet.Optical emission spectroscopy analysis is also employed to create spatial maps of the photonic intensity distribution within the plasma jet when different additional gases are injected into it.The CE–MIP torch is experimentally tested for surface energy modification on glass where it creates a super-hydrophilic surface. | Adam BENNETT Nan YU Fengzhou FANG Marco CASTELLI Guoda CHEN Alessio BALLERI Takuya URAYAMA | 2021 | Frontiers of Mechanical Engineering2021，16，1： | 2 |
| 9 | The emerging role of probiotics in neurodegenerative diseases:new hope for Parkinson’s disease?显示文摘Neurodegenerative disease etiology is still unclear,but different contributing factors,such as lifestyle and genetic factors are involved.Altered components of the gut could play a key role in the gut-brain axis,which is a bidirectional system between the central nervous system and the enteric nervous system.Variations in the composition of the gut microbiota and its function between healthy people and patients have been reported for a variety of human disorders comprising metabolic,autoimmune,cancer,and,notably,neurodegenerative disorders.Diet can alter the microbiota composition,affecting the gutbrain axis function.Different nutraceutical interventions have been devoted to normalizing gut microbiome dysbiosis and to improving biological outcomes in neurological conditions,including the use of probiotics.Preclinical and clinical investigations discussed in this review strengthen the correlation between intestinal microbiota and brain and the concept that modifying the microbiome composition may improve brain neurochemistry,modulating different pathways.This review will discuss the potential use of probiotics for Parkinson’s disease prevention or treatment or as adjuvant therapy,confirming that gut microbiota modulation influences different pro-survival pathways.Future investigations in Parkinson’s disease should consider the role of the gut-brain axis and additional comprehension of the underlying mechanisms is extremely necessary. | Vanessa Castelli Michele d’Angelo Massimiliano Quintiliani Elisabetta Benedetti Maria Grazia Cifone Annamaria Cimini | 2021 | Neural Regeneration Research2021，16，4： | 2 |
| 10 | Multimodal approach to endovascular treatment of visceral artery aneurysms and pseudoaneurysms显示文摘 | Domenico Laganà Gianpaolo Carrafiello Monica Mangini Gianlorenzo Dionigi Roberto Caronno Patrizio Castelli Carlo Fugazzola | 2006 | European Journal of Radiology2006，，1： | 2 |
| 11 | Novel Approaches for Preventing or Limiting Events (Naples) II Trial显示文摘 | Carlo Briguori Gabriella Visconti Amelia Focaccio Bruno Golia Alaide Chieffo Alfredo Castelli Marco Mussardo Matteo Montorfano Bruno Ricciardelli Antonio Colombo | 2009 | Journal of the American College of Cardiology2009，，23： | 2 |
| 12 | Design of a motorised plasma delivery system for ultra-precision large optical fabrication显示文摘A unique plasma figuring(PF)process was created and demonstrated at Cranfield University for manufacturing extremely large telescopes.The atmospheric pressure processing is faster and more cost-effective than other finishing processes;thus,providing an important alternative for large optical surfaces.The industrial scale manufacturing of thousands of ultra-precision metre-scale optics requires a robust PF machine:this requirement is achieved by making the plasma delivery system(PDS)performance repeatable.In this study,a dedicated PDS for large optical manufacturing was proposed to meet the industrial requirement.The PDS is based on an L-type radiofrequency(RF)network,a power supply,and an inductively coupled plasma torch.However,the complexities of these technologies require an in depth understanding of the integrated components that from the PDS.A smart control system for the modified PDS was created.This novel control system aims to make the characterization process deterministic:by automating the tuning of critical electrical components in the RF network,which is achieved by the use of in-line metrology.This paper describes the main design aspects.The PDS was tested with a good correlation between capacitance and RF frequencies.The robust PDS design enables a stable discharge of plasma with a low deviation of RF signals during the total15 hours’test. | Hui Zhou Adam Bennett Marco Castelli Renaud Jourdain Jiang Guo Nan Yu | 2020 | International Journal of Extreme Manufacturing2020，2，4： | 2 |
| 13 | Fibrinogen and risk of cardiovascular disease显示文摘 | Kannel WB Wolf PA Castelli WP | 1987 | JAMA1987，258，10： | 1 |
| 14 | Identification of epitope mimics recognized by CTL reactive to the melanoma/melanocyte-derived peptide MART-l(27-35)显示文摘 | Castelli C Clayfi TM | 1996 | J Exp Med1996，184，： | 1 |
| 15 | Abundances of Four Very Metal-poor Stars of the BPS Survey显示文摘 | PRIMAS P MOLARO P CASTELLI F | 1994 | A&A1994，290，： | 1 |
| 16 | The natural history of congestive heart failure : the Framingham study 显示文摘 | McKee PA Castelli WP McNamara PM | 1971 | N Engl J Med1971，285，26： | 1 |
| 17 | Epidemiology of coronary heart disease:the framingham study显示文摘 | Castelli WP | 1984 | Am J Med1984，76，2： | 1 |
| 18 | Making practical sense of clinical trial data in de-creasing risk显示文摘 | Castelli WP | 2001 | Am J Cardiol2001，88，4： | 1 |
| 19 | HOPS: a novel cAMP - dependent shuttling protein involved in protein synthesis regulation显示文摘 | Della Fazia MA Castelli M Bartoli D | 2005 | J Cell Sci2005，118，14： | 1 |
| 20 | The Design of a Market Mechanism to Allocate Air Traffic Flow Management Slots 显示文摘 | Castelli L Pesenti R Ranieri A | 2011 | Transportation Research Part C2011，1，19： | 1 |
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