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| 1 | Identification of coastal wetlands of international importance for waterbirds:a review of China Coastal Waterbird Surveys 2005–2013显示文摘Background:China's coastal wetlands belong to some of the most threatened ecosystems worldwide.The loss and degradation of these wetlands seriously threaten waterbirds that depend on wetlands.Methods:The China Coastal Waterbird Census was organized by volunteer birdwatchers in China's coastal region.Waterbirds were surveyed synchronously once every month at 14 sites,as well as irregularly at a further 18 sites,between September 2005 and December 2013.Results:A total of 75 species of waterbirds met the 1 % population level Ramsar listing criterion at least once at one site.The number of birds of the following species accounted for over 20 % of the total flyway populations at a single site:Mute Swan(Cygnus olor),Siberia Crane(Grus leucogeranus),Far Eastern Oystercatcher(Haematopus osculans),Bar-tailed Godwit(Limosa lapponica),Spotted Greenshank(Tringa guttifer),Great Knot(Calidris tenuirostris),Spoon-billed Sandpiper(Calidris pygmeus),Saunders' s Gull(Larus saundersi),Relict Gull(Larus relictus),Great Cormorant(Phalacrocorax carbo),Eurasian Spoonbill(Platalea leucorodia),Black-faced Spoonbill(Platalea minor) and Dalmatian Pelican(Pelecanus crispus).A total of 26 sites supported at least one species of which their number met the1 % criterion.Forty-two species met the 1 % criterion in the Yellow River Delta,Shandong;29 at the Cangzhou coast,Hebei and 26 species at the Lianyungang coast,Jiangsu.Conclusions:The results highlight the international importance of China's coastal wetlands for waterbirds.This study also demonstrates that participation of local birdwatchers in waterbird surveys results in data that are invaluable not only for understanding the current status of waterbirds in China's coastal regions but also for waterbird conservation and management. | Qingquan Bai Jianzhong Chen Zhihong Chen Guotai Dong Jiangtian Dong Wenxiao Dong Vivian Wing Kan Fu Yongxiang Han Gang Lu Jing Li Yang Liu Zhi Lin Derong Meng Jonathan Martinez Guanghui Ni Kai Shan Renjie Sun Suixing Tian Fengqin Wang Zhiwei Xu Yat-tung Yu Jin Yang Zhidong Yang Lin Zhang Ming Zhang Xiangwu Zeng | 2015 | Chinese Birds2015，，3： | 20 |
| 2 | Downregulation of Hes1 expression in experimental biliary atresia and its effects on bile duct structure显示文摘AIM To analyze the expression and function of the notchsignaling target gene Hes1 in a rhesus rotavirusinduced mouse biliary atresia model. METHODS The morphologies of biliary epithelial cells in biliary atresia patients and in a mouse model were examined by immunohistochemical staining. Then, the differential expression of Notch signaling pathway-related molecules was investigated. Further, the effects of the si RNAmediated inhibition of Hes1 expression were examined using a biliary epithelial cell 3 D culture system.RESULTS Both immature(Ep CAM+) and mature(CK19+) biliary epithelial cells were detected in the livers of biliary atresia patients without a ductile structure and in the mouse model with a distorted bile duct structure. The hepatic expression of transcripts for most Notch signaling molecules were significantly reduced on day 7 but recovered to normal levels by day 14, except for the target molecule Hes1, which still exhibited lower m RNA and protein levels. Expression of the Hes1 transcriptional co-regulator, RBP-Jκ was also reduced. A 3 D gel culture system promoted the maturation of immature biliary epithelial cells, with increased expression of CK19+ cells and the formation of a duct-like structure. The administration of Hes1 si RNA blocked this process. As a result, the cells remained in an immature state, and no duct-like structure was observed.CONCLUSION Our data indicated that Hes1 might contribute to the maturation and the cellular structure organization of biliary epithelial cells, which provides new insight into understanding the pathology of biliary atresia. | Rui-Zhong Zhang Xin-Hao Zeng Ze-Feng Lin Ming-Fu Yan-Lu Tong Vincent CH Lui Paul KH Tam Jonathan R Lamb Hui-Min Xia Yan Chen | 2018 | World Journal of Gastroenterology2018，24，29： | 5 |
| 3 | Double Nicking by RNA-Guided CRISPR Cas9 for Enhanced Genome Editing Specificity显示文摘 | F. Ann Ran Patrick D. Hsu Chie-Yu Lin Jonathan S. Gootenberg Silvana Konermann Alexandro E. Trevino David A. Scott Azusa Inoue Shogo Matoba Yi Zhang Feng Zhang | 2013 | Cell2013，，2： | 4 |
| 4 | ncRNA- and Pc2 Methylation-Dependent Gene Relocation between Nuclear Structures Mediates Gene Activation Programs显示文摘 | Liuqing Yang Chunru Lin Wen Liu Jie Zhang Kenneth A. Ohgi Jonathan D. Grinstein Pieter C. Dorrestein Michael G. Rosenfeld | 2011 | Cell2011，，4： | 2 |
| 5 | The Strength of Structural Diversity in Online Social Networks显示文摘Understanding the way individuals are interconnected in social networks is of prime significance to predict their collective outcomes.Leveraging a large-scale dataset from a knowledge-sharing website,this paper presents an exploratory investigation of the way to depict structural diversity in directed networks and how it can be utilized to predict one’s online social reputation.To capture the structural diversity of an individual,we first consider the number of weakly and strongly connected components in one’s contact neighborhood and further take the coexposure network of social neighbors into consideration.We show empirical evidence that the structural diversity of an individual is able to provide valuable insights to predict personal online social reputation,and the inclusion of a coexposure network provides an additional ingredient to achieve that goal.After synthetically controlling several possible confounding factors through matching experiments,structural diversity still plays a nonnegligible role in the prediction of personal online social reputation.Our work constitutes one of the first attempts to empirically study structural diversity in directed networks and has practical implications for a range of domains,such as social influence and collective intelligence studies. | Yafei Zhang Lin Wang Jonathan JHZhu Xiaofan Wang Alex‘Sandy’Pentland | 2021 | Research2021，，1： | 2 |
| 6 | A potato late blight resistance gene protects against multiple Phytophthora species by recognizing a broadly conserved RXLR-WY effector显示文摘Species of the genus Phytophthora,the plant killer,cause disease and reduce yields in many crop plants.Although many Resistance to Phytophthora infestans(Rpi)genes effective against potato late blight have been cloned,few have been cloned against other Phytophthora species.Most Rpi genes encode nucleotide-binding domain,leucine-rich repeat-containing(NLR)immune receptor proteins that recognize RXLR(Arg-X-Leu-Arg)effectors.However,whether NLR proteins can recognize RXLR effectors from multiple Phytophthora species has rarely been investigated.Here,we identified a new RXLR-WY effector AVRamr3 from P.infestans that is recognized by Rpi-amr3 from a wild Solanaceae species Solanum americanum.Rpi-amr3 associates with AVRamr3 in planta.AVRamr3 is broadly conserved in many different Phytophthora species,and the recognition of AVRamr3 homologs by Rpi-amr3 activates resistance against multiple Phytophthora pathogens,including the tobacco black shank disease and cacao black pod disease pathogens P.parasitica and P.palmivora.Rpi-amr3 is thus the first characterized resistance gene that acts against P.parasitica or P.palmivora.These findings suggest a novel path to redeploy known R genes against different important plant pathogens. | Xiao Lin Andrea Olave-Achury Robert Heal Marina Pais Kamil Witek Hee-Kyung Ahn He Zhao Shivani Bhanvadia Hari S.Karki Tianqiao Song Chih-hang Wu Hiroaki Adachi Sophien Kamoun Vivianne G.A.A.Vleeshouwers Jonathan D.G.Jones | 2022 | Molecular Plant2022，15，9： | 2 |
| 7 | Regulation of NF-κB, Th Activation, and Autoinflammation by the Forkhead Transcription Factor Foxo3a显示文摘 | Ling Lin Jonathan D. Hron Stanford L. Peng | 2004 | Immunity2004，，2： | 2 |
| 8 | Plant hormone effect of antibiotics on transformation efficient of plant tissue by Agrobacterium tumefaciens cells显示文摘 | Lin J J Nacyra A G Jonathan K | | 0，，02： | 1 |
| 9 | Selected loss of tolerance evidenced by Crohn’s disease–associated immune responses to auto- and microbial antigens显示文摘 | Carol J. Landers Offer Cohavy Rajeev Misra Huiying Yang Ying–Chao Lin Jonathan Braun Stephan R. Targan | 2002 | Gastroenterology2002，，： | 1 |
| 10 | One-pot synthesis of 2,5-bis(hydroxymethyl)furan from biomass derived 5-(chloromethyl)furfural in high yield显示文摘5-(Chloromethyl)furfural(CMF),as a new platform molecular,has become a hot topic in the field of biorefinery.Herein,the one-pot conversion of CMF to 2,5-bis(hydroxymethyl)furan(BHMF)in the water phase was demonstrated for the first time.A 91%BHMF yield was obtained over Ru/Cu Oxcatalyst,and BHMF was mainly produced by the consecutive hydrolysis and hydrogenation of CMF with 5-hydroxymethylfurfural(HMF)as an intermediate.Kinetic studies revealed that the conversion of HMF to BHMF was the rate-determining step.Remarkably,the characterizations and density functional theory(DFT)calculations further revealed the lower electron density of Ru NPs in Ru/Cu Oxcatalyst,resulting in a larger adsorption energy and a smaller free energy difference for the formation of alcohols.The present findings offered a new pathway for biomass-derived diol production through CMF as a potential source. | Binglin Chen Yunchao Feng Sen Ma Weizhen Xie Guihua Yan Zheng Li Jonathan Sperry Shuliang Yang Xing Tang Yong Sun Lu Lin Xianhai Zeng | 2023 | Journal of Energy Chemistry2023，，1： | 1 |
| 11 | Small noncoding RNAs in the germline 显示文摘 | Saxe Jonathan P Lin HF | 2011 | Cold Spring Harbor Perspectives in Biology2011，3，00： | 1 |
| 12 | Plant hormone effect of antibi-otics on the transformation efficiency of plant tissue by Agrobacteriumtumefaciens cells显示文摘 | Lin J J Assad-Garcia N Jonathan K | 1995 | Plant Science1995，109，2： | 1 |
| 13 | High-throughput physical phenotyping of cell differentiation显示文摘In this report,we present multiparameter deformability cytometry(m-DC),in which we explore a large set of parameters describing the physical phenotypes of pluripotent cells and their derivatives.m-DC utilizes microfluidic inertial focusing and hydrodynamic stretching of single cells in conjunction with high-speed video recording to realize high-throughput characterization of over 20 different cell motion and morphology-derived parameters.Parameters extracted from videos include size,deformability,deformation kinetics,and morphology.We train support vector machines that provide evidence that these additional physical measurements improve classification of induced pluripotent stem cells,mesenchymal stem cells,neural stem cells,and their derivatives compared to size and deformability alone.In addition,we utilize visual interactive stochastic neighbor embedding to visually map the high-dimensional physical phenotypic spaces occupied by these stem cells and their progeny and the pathways traversed during differentiation.This report demonstrates the potential of m-DC for improving understanding of physical differences that arise as cells differentiate and identifying cell subpopulations in a label-free manner.Ultimately,such approaches could broaden our understanding of subtle changes in cell phenotypes and their roles in human biology. | Jonathan Lin Donghyuk Kim Henry T.Tse Peter Tseng Lillian Peng Manjima Dhar Saravanan Karumbayaram Dino Di Carlo | 2017 | Microsystems & Nanoengineering2017，3，1： | 1 |
| 14 | A Prospective, Randomized, Controlled Trial of Single-Incision Laparoscopic (SILS) versus Conventional 3-port Laparoscopic Appendectomy for the Treatment of Acute Appendicitis显示文摘 | Jonathan T. Carter Jennifer A. Kaplan Jason N. Nguyen Matthew Y.C. Lin Stanley J. Rogers Hobart W. Harris | 2013 | Journal of the American College of Surgeons2013，，： | 1 |
| 15 | Plant Hormone Effect of Antibiotics on Transformation Fficient of Plant Tis sue by Agrobacterium tumefaciens Cells 显示文摘 | LIN J J NACYRA A G JONATHAN K | 1995 | Plant Scince1995，109，2： | 1 |
| 16 | 2021年ISHNE/HRS/EHRA/APHRS关于移动医疗心律失常管理共识:心脏节律专业人员的数字医疗工具显示文摘国际动态心电图和无创心电图学会/心律学会/欧洲心律协会/亚太心律协会制定的'关于移动医疗心律失常管理共识'描述了移动医疗(mHealth)技术在心律失常管理中的现状,涉及数字医疗工具范围,以及可能应用于心律失常的诊断和协助临床决策。合并症和生活方式管理(日益公认在心律失常中起作用)以及患者自我管理赋予了mHealth新的内容。共识对预测分析的承诺,以及嵌入了mHealth的常规临床关怀的操作面临的挑战,进行了探讨。 | Niraj Varma Iwona Cygankiewicz Mintu Turakhia Hein Heidbuchel Yufeng Hu Lin Yee Chen Jean-Philippe Couderc Edmond M.Cronin Jerry D.Estep Lars Grieten Deirdre A.Lane Reena Mehra Alex Page Rod Passman Jonathan Piccini Ewa Piotrowicz Ryszard Piotrowicz Pyotr G.Platonov Antonio Luiz Ribeiro Robert E.Rich Andrea M.Russo David Slotwiner Jonathan S.Steinberg Emma Svennberg 蔡星星(翻译) 陈牧(翻译) 陈泰中(翻译) 费聿东(翻译) 费振涛(翻译) 龚畅祺(翻译) 胡晓亮(翻译) 李澄(翻译) 练小铭(翻译) 莫斌峰(翻译) 王海成(翻译) 王倩(翻译) 卫郅星(翻译) 徐全福(翻译) 杨眉(翻译) 杨钰粒(翻译) 于怡驰(翻译) 张睿(翻译) 赵铭哲(翻译) 赵晏(翻译) 李毅刚(审校) 王群山(审校) | 2021 | 中国心脏起搏与心电生理杂志2021，35，2： | 1 |
| 17 | The concave iris in pigment dispersion syndrome显示文摘 | LANCE L EE LIN O JONATHAN C | 2011 | Ophthalmology2011，118，1： | 1 |
| 18 | Correlation of AIB1 overexpression with advanced clinical stage of human colorectal carcinoma显示文摘 | Dan Xie Jonathan S.T. Sham Wei-Fen Zeng Han-Liang Lin Jiong Bi Li-Hong Che Liang Hu Yi-Xin Zeng Xin-Yuan Guan | 2005 | Human Pathology2005，，7： | 1 |
| 19 | Antibodies against low-density lipoprotein receptor-related protein 4 induce myasthenia gravis显示文摘 | Shen Chengyong Lu Yisheng Zhang Bin Figueiredo Dwight Bean Jonathan Jung Jiung Wu Haitao Barik Arnab Yin Dong-Min Xiong Wen-Cheng Mei Lin | 2013 | Journal of Clinical Investigation2013，，12： | 1 |
| 20 | Plant hormone effect of antibiotics on transformation efficient of plant tissue by Agrobacterium tumefaciens cells显示文摘 | Lin J J Nacyra A G Jonathan K | 1995 | Plant Sci1995，109，： | 1 |
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