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| 1 | Rock burst mechanism analysis in an advanced segment of gob-side entry under different dip angles of the seam and prevention technology显示文摘In order to investigate the frequent occurrences of rock burst in gob-side entry during the mining process of the mining zone No. 7, the mechanical model of main roof of fully-mechanized caving mining before breaking was established by the Winkler foundation beam theory, and the stress evolution law of surrounding rock with different dip angles of the seam during the mining process was analyzed by using FLAC3 D. The results show that: with the dip angle changing from 45° to 0°, the solid-coal side of gobside entry begins to form an L-shaped stress concentration zone at a dip angle of 30°, and the stress concentration degree goes to higher and higher levels. However, the stress concentration degree of the coalpillar side goes to lower and lower levels; the influence range and peak stress of the abutment at the lateral strata of adjacent gob increase with dip angle decreasing and reach a maximum value at a dip angle of 0°, but the tailgate is not affected; the abutment pressure superposition of two adjacent gobs leads to stress concentration further enhancing in both sides of gob-side entry. With the influence of strong mining disturbance, rock burst is easily induced by dynamic and static combined load in the advanced segment of gob-side entry. To achieve stability control similar to that in the roadway, the key control strategy is to reinforce surrounding rock and unload both sides. Accordingly, the large-diameter drilling and high-pressure water injection combined unloading and reinforced support cooperative control technology was proposed and applied in field test. The results of Electromagnetic Emission(EME) and field observation showed that unloading and surrounding rock control effect was obvious. | Yang Zengqiang Liu Chang Tang Shichuan Dou Linming Cao Jinglong | 2018 | International Journal of Mining Science and Technology2018,28,6: | 24 |
| 2 | Photochemical pollution in Lanzhou, China - A case study显示文摘The photochemical air pollution in Xigu district of Lanshou city, Gansu Province was studied during a period of 1981-1984. The extremely high NMHC/NOx ratio and ozone level elevation after rain have been noticed. A series of outdoor and indoor reaction chamber simulation experiments conducted in order to understand the specific conditions. The ozone formation under NMHC/NOx condition and the possible reason for high ozone concentration after rain are discussed. | Tang Xiaoyan , Li Jinglong, Dong ZhenXing, Wang Yuying,Wang Wenxing , Qi Liwen, Liu Xiling, Zhang Yutian, Zhang Xuejin,Tian Bingshen, Jin Suwen , Yang Lingqing and Zhang Yixin Department of Technical Physics,Peking University, Beijing, China. Chinese Reaearch Academy of Eavironmental Sciences, Beijing,China. Gansu Provincial Environmental Research Institute, Lanshou, China. Lanshou Petrochemical Engineering Institute, Lanshou, China. | 1989 | Journal of Environmental Sciences1989,1,1: | 15 |
| 3 | Antibacterial Behavior of a Cu-bearing Type 200 Stainless Steel显示文摘A preliminary study was made on the antibacterial behavior of a newly designed Cu-bearing type 200 stainless steel by different methods including Vickers hardness measurement, electrochemical test and antibacterial test. The results showed that Cu-rich precipitations caused by the saturated Cu in the steel matrix was not only a crucial factor for its excellent antibacterial capability, but also for its equivalent corrosion resistance as good as the commercial type 200 stainless steel. | Li Nan Jinglong Cheng Ke Yang | 2012 | Journal of Materials Science & Technology2012,28,11: | 12 |
| 4 | Decomposition of acid dissolved titanium slag from Australia by sodium hydroxide显示文摘The kinetics of the decomposition of acid dissolved titanium slag with a sodium hydroxide system under atmospheric pressure was studied. The effect of reaction temperature, particle size and NaOH-to-slag mass ratio on titanium extraction was investigated. The results show that temperature and particle size have significant influence on titanium extraction. The experimental data of titanium extraction show that the shrinking core model with chemical reaction controlled process is most applicable for the decomposition of slag, with an apparent activation energy of 62.4 kJ·mol-1. Approximately 85 wt.%-90 wt.% of the titanium can be extracted from the slag under the optimal conditions. In addition, the purity of titanium dioxide obtained in the product is up to 98.5 wt.%. | FENG Yang WANG Jinggang WANG Lina QI Tao XUE Tianyan CHU Jinglong | 2009 | Rare Metals2009,28,6: | 5 |
| 5 | QNE1 is a key flowering regulator determining the length of the vegetative period in soybean cultivars显示文摘The soybean E1 gene is a major regulator that plays an important role in flowering time and maturity.However,it remains unclear how cultivars carrying the dominant E1 allele adapt to the higher latitudinal areas of northern China.We mapped the novel quantitative trait locus QNE1(QTL near E1) for flowering time to the region proximal to E1 on chromosome 6 in two mapping populations.Positional cloning revealed Glyma.06G204300,encoding a TCP-type transcription factor,as a strong candidate gene for QNE1.Association analysis further confirmed that functional single nucleotide polymorphisms(SNPs) at nucleotides 686 and 1,063 in the coding region of Glyma.06G204300 were significantly associated with flowering time.The protein encoded by the candidate gene is localized primarily to the nucleus.Furthermore,soybean and Brassica napus plants overexpressing Glyma.06G204300 exhibited early flowering.We conclude that despite their similar effects on flowering time,QNE1 and E4 may control flowering time through different regulatory mechanisms,based on expression studies and weighted gene co-expression network analysis of flowering time-related genes.Deciphering the molecular basis of QNE1 control of flowering time enriches our knowledge of flowering gene networks in soybean and will facilitate breeding soybean cultivars with broader latitudinal adaptation. | Zhengjun Xia Hong Zhai Yanfeng Zhang Yaying Wang Lu Wang Kun Xu Hongyan Wu Jinglong Zhu Shuang Jiao Zhao Wan Xiaobin Zhu Yi Gao Yingxiang Liu Rong Fan Shihao Wu Xin Chen Jinyu Liu Jiayin Yang Qijian Song Zhixi Tian | 2022 | Science China(Life Sciences)2022,65,12: | 1 |
| 6 | Promi- nent activation of the bilateral inferior parietal lob- ule of literate compared with illiterate subjects dur- ing Chinese logographic processing 显示文摘 | Wu Jinglong Li Xiujun Yang Jiajia | 2012 | Exp Brain Res2012,219,: | 1 |
| 7 | Liquid-like polymer lubricating surfaces:Mechanism and applications显示文摘Liquid-like polymer lubricating surfaces(LPLSs)are solid substrates with highly flexible polymer chains grafted via covalent bonds.This unique modification enables ultralow contact-angle hysteresis,repellency of various liquids and bulk ice,and stability.The distinctive wettability and universality of LPLSs have potential applications in liquid motion,biological detection,and environmental protection.In this review,we summarize the mechanisms,preparation,and applications of LPLSs.We discuss the wettability and lubrication mechanisms of liquid droplets on LPLSs.We then categorize LPLS fabrication into“grafted onto”and“grafted from”groups,depending on the type of polymer.We highlight representative applications with recent developments in anti-complex liquid,anti-icing,anti-biological adhesions,biosensing,and photocatalytic activity.Finally,we discuss future challenges and outlooks for LPLSs. | Dagui Wang Jinglong Yang Junchang Guo Zhijuan Duan Deihui Wang Fan Xia Fei Deng Xu Deng | 2024 | Nano Research2024,17,2: | 1 |
| 8 | A preliminary study on calculating method for the evolution of siltation and erosion of tidal flat based on GIS显示文摘 | Du Jinglong Gao ang Yang shilun | 2005 | Marine Science Bullein2005,7,1: | 1 |
| 9 | Coating of Silicon Nitride and its Colloidal Behavior显示文摘 | Qiang Tang Zhipeng Xie Jinglong Yang Yong Huang | 1998 | Journal of Materials Science Letters1998,,14: | 1 |
| 10 | Breeding of Saccharomyces cerevisiae显示文摘With three Saccharomyces cerevisiae strains collected by Institute of Modern Brewing Apparatus and Technology of Qilu University of Technology as experimental materials,an excellent S.cerevisiae strain,R2-b,was selected by the plate separation culture method through the selection of separation medium,observation of appearance of yeast colonies,cell morphology and cell size,and the determination of cell death rate,diacetyl content,reducing power and fermentation power.The yeast strain can meet the demand for fermentation of fresh beer. | Chuan YANG Jinglong LI | 2019 | Agricultural Biotechnology2019,8,4: | 1 |
| 11 | Pedal Errors Among Younger and Older Individuals During Different Pedal Operating Conditions 显示文摘 | Wu Jinglong Yang Jiajia Yoshitake | 2014 | Human Factors2014,56,4: | 1 |
| 12 | Particle Sizes and Antibacterial Activity of Radix Astragalus and Radix Isatidis Ultrafine Powders显示文摘Using 9200 laser particle size analyzer and KYKY-2800 scanning electron microscope,particle sizes and cellular morphology of Radix Astragalus and Radix Isatidis ultrafine powders were observed. According to the results,the particle size of 89.1% of Radix Astragalus ultrafine powders ranged from 1.729 μm to 44. 938 μm,D_(50)=4.368 μm; t he particle size of 93.411% of Radix Isatidis ultrafine powders ranged from 1. 510 μm to 44. 938 μm,D50= 8.726 μm. Radix Astragalus and Radix Isatidis ultrafine powders were pulverized completely without intact cellular morphology. The antibacterial activity of Radix Astragalus and Radix Isatidis ultrafine powders against chicken-derived E. coli(O78) w as investigated. The results indicated that Radix Astragalus and Radix Isatidis ultrafine powders exhibited higher antibacterial activity against chicken-derived E. coli(O78) c ompared with the corresponding coarse powders. This study laid a solid foundation for the development and application of Chinese medicine ultrafine powder preparations. | Qiumei SHI Xinhua SHAO Xiumin WANG Xia MENG Xiaoqiao HOU Baoxin YANG Leiyu GUO Jinglong GAO | 2016 | Agricultural Biotechnology2016,5,4: | 1 |
| 13 | The effect of different coatings on bone response and degradation behavior of porous magnesium-strontium devices in segmental defect regeneration显示文摘Regeneration of long-bone segmental defects remains a challenge for orthopedic surgery.Current treatment options often require several revision procedures to maintain acceptable alignment and achieve osseous healing.A novel hollow tubular system utilizing magnesium-strontium(Mg-Sr)alloy with autogenous morselized bone filled inside to repair segmental defects was developed.To improve the corrosion and biocompatible properties,two coatings,Ca-P and Sr-P coatings,were prepared on surface of the implants.Feasibility of applying these coated implants was systematically evaluated in vitro and in vivo,and simultaneously to have a better understanding on the relationship of degradation and bone regeneration on the healing process.According to the in vitro corrosion study by electrochemical measurements,greater corrosion resistance was obtained for Ca-P coated sample,and attributed to the double-layer protective structure.The cytotoxicity and alkaline phosphatase(ALP)assays demonstrated enhanced bioactivity for Sr-P coated group because of the long-lasting release of beneficial Sr^(2+).At 12 weeks post-implantation with Mg-Sr alloy porous device,the segmental defects were effectively repaired with respect to both integrity and continuity.In addition,compared with the Ca-P coated implant,the Sr-P coated implant was more proficient at promoting bone formation and mineralization.In summary,the Sr-P coated implants have bioactive properties and exceptional durability,and promote bone healing that is close to the natural rate,implying their potential application for the regeneration of segmental defects. | Nan Zhang Weidan Wang Xiuzhi Zhang Krishna.C.Nune Ying Zhao Na Liu R.D.K.Misra Ke Yang Lili Tan Jinglong Yan | 2021 | Bioactive Materials2021,6,6: | 1 |
| 14 | Comparison of summer chlorophyll a concentration in the South China Sea and the Arabian Sea using remote sensing data显示文摘The South China Sea(SCS) and the Arabian Sea(AS) are both located roughly in the north tropical zone with a range of similar latitude(0°–24°N). Monsoon winds play similar roles in the upper oceanic circulations of the both seas. But the distinct patterns of chlorophyll a(Chl a) concentration are observed between the SCS and the AS.The Chl a concentration in the SCS is generally lower than that in the AS in summer(June–August); the summer Chl a concentration in the AS shows stronger interannual variation, compared with that in the SCS; Moderate resolution imaging spectroradiometer(MODIS)-derived data present higher atmospheric aerosol deposition and stronger wind speed in the AS. And it has also been found that good correlations exist between the index of the dust precipitation indicated by aerosol optical thickness(AOT) and the Chl a concentration, or between wind and Chl a concentration. These imply that the wind and the dust precipitation bring more nutrients into the AS from the sky, the sub-layer or coast regions, inducing higher Chl a concentration. The results indicate that the wind velocity and the dust precipitation can play important roles in the Chl a concentration for the AS and the SCS in summer. However aerosol impact is weak on the biological productivity in the west SCS and wind-induced upwelling is the main source. | YAO Jinglong YANG Lei SHU Yeqiang ZENG Lili SHI Rui CHEN Ju ZU Tingting CHEN Chuqun | 2017 | Acta Oceanologica Sinica2017,36,11: | 1 |
| 15 | Simultaneous enhancement of strength and ductility in friction stir processed 2205 duplex stainless steel with a bimodal structure:experiments and crystal plasticity modeling显示文摘Achieving excellent strength-ductility synergy is a long-lasting research theme for structural materials.However,attempts to enhance strength usually induce a loss of ductility,i.e.,the strength-ductility trade-off.In the present study,the strength-ductility trade-off in duplex stainless steel(DSS)was overcome by developing a bimodal structure using friction stir processing(FSP).The ultimate tensile strength and elongation were improved by 140%and 109%,respectively,compared with those of the asreceived materials.Plastic deformation and concurrent dynamic recrystallization(DRX)during FSP were responsible for the formation of bimodal structure.Incompatible deformation resulted in the accumulation of dislocations at the phase boundaries,which triggered interpenetrating nucleation between the austenite and ferrite phases during DRX,leading to a bimodal structure.The in situ mechanical responses of the bimodal structure during tensile deformation were investigated by crystal plasticity finite element modeling(CPFEM).The stress field distribution obtained from CPFEM revealed that the simultaneous enhancement of strength and ductility in a bimodal structure could be attributed to the formation of a unique dispersion-strengthened system with the austenite and ferrite phases.It is indicated that the present design of alternating fine austenite and coarse ferrite layers is a promising strategy for optimizing the mechanical properties of DSSs. | Yanying Hu Zexin Fang Yongbing Peng Weiqi Yang Xianfeng Ma Jinglong Li Yunqiang Zhao Biao Wang | 2022 | Science China(Physics,Mechanics & Astronomy)2022,65,2: | 0 |
| 16 | Allogeneic gene-edited HIV-specific CAR-T cells secreting PD-1 blocking scFv enhance specific cytotoxic activity against HIV Envt cells in vivo显示文摘HIV-specific chimeric antigen receptor(CAR)T-cells have been developed to target HIV-1 infected CD4t T-cells that express HIV Env proteins.However,T cell exhaustion and the patient-specific autologous paradigm of CAR-T cell hurdled clinical applications.Here,we created HIV-specific CAR-T cells using human peripheral blood mononuclear cells and a 3BNC117-E27(3BE)CAR construct that enabled the expression of programmed cell death protein(PD-1)-blocking scFv E27 and the single-chain variable fragment of the HIV-1-specific broadly neutralizing antibody 3BNC117 to target native HIV Env.Compared with T cells expressing 3BNC117-CAR alone,3BE CAR-T cells showed greater cytotoxic activity against HIV Envt cells with stronger proliferation capability,higher killing efficiency,and enhanced cytokine secretion in the presence of HIV Env-expressing cells.Furthermore,we manufactured TCR-deficient 3BE CAR-T cells through gene editing and demonstrated that these CAR-T cells could effectively kill HIV Env^(+) cells in vivo without the occurrence of severe graft-versus-host disease(GvHD)in NSG mice.These data suggest that we have provided a feasible approach to the generation of“off-theshelf”anti-HIV CAR-T cells in combination with PD-1 checkpoint blockade immunotherapy,which can be a powerful therapeutic candidate for the functional cure of HIV. | Hanyu Pan Xinyi Yang Jing Wang Huitong Liang Zhengtao Jiang Lin Zhao Yanan Wang Zhiming Liang Xiaoting Shen Qinru Lin Yue Liang Jinglong Yang Panpan Lu Yuqi Zhu Min Li Pengfei Wang Jianqing Xu Hongzhou Lu Huanzhang Zhu | 2023 | Virologica Sinica2023,38,2: | 0 |
| 17 | High speed laser cladding as a new approach to prepare ultra-high temperature ceramic coatings显示文摘Ultra-high temperature ceramic(UHTC)coatings are used to protect the hot-end components of hypervelocity aerocrafts from thermal ablation.This study provides a new approach to fabricate UHTC coatings with high speed laser cladding(HSLC)technology,and places more emphasis on investigating the formation mechanism,phase compositions,and mechanical properties of HSLC-UHTC coatings.Results show that a well-bonded interface between the coating and the tantalum alloy substrate can be formed.The coating is mainly composed of(Zr,Ta)C ceramic solid solution phase with a content of higher than 90% by volume and Ta(W)metal solid solution phase.At a relatively high powder feeding rate,the ZrC ceramic phase appears in the coating while a dense ZrC UHTC top layer with a thickness of up to~50μm is successfully fabricated.As for the mechanical properties of the HSLC coatings,the fracture toughness of the coating decreases with the increase of powder feeding rate.The increase of carbide solid solution phase can significantly improve the high temperature microhardness(552.7±1.8 HV0.5@1000℃).The innovative design of HSLC ZrC-based coatings on refractory alloys accomplishes continuous transitions on microstructure and properties from the substrate to the UHTC top layer,which is a very promising candidate scheme for thermal protection coating. | Qiyao Deng Pengfei He Chuan Sun Yang Li Yue Xing Yujie Wang Jinglong Li Xiubing Liang Xin Wang Yujie Zhou Yujun Cai | 2024 | Journal of Advanced Ceramics2024,13,2: | 0 |
| 18 | Big-data-accelerated aperiodic Si/Ge superlattice prediction for quenching thermal conduction via pattern analysis显示文摘Thermal conductivity of material is one of the basic physical properties and plays an important role in manipu-lating thermal energy.In order to accelerate the prediction of material structure with desired thermal property,machine learning algorithm has been widely adopted.However,in the optimization of multivariable material structure such as different lengths or proportions,the machine learning algorithm may be required to be recon-ducted again and again for each variable,which will consume a lot of computing resources.Recently,it has been found that the thermal conductivity of aperiodic superlattices is closely related to the degree of the structural ran-domness,which can also be reflected in their local pattern structures.Inspired by these,we propose a new pattern analysis method,in which machine learning only needs to be carried out for one time,and through which the optimal structure of different variables with low thermal conductivity can be obtained.To verify the method,we compare the thermal conductivities of the structure obtained by pattern analysis,conventional machine learning,and previous literature,respectively.The pattern analysis method is validated to greatly reduce the prediction time of multivariable structure with high enough accuracy and may promote further development of material informatics. | Yida Liu Run Hu Yan Wang Jinglong Ma Zhangcan Yang Xiaobing Luo | 2021 | Energy and AI2021,3,1: | 0 |
| 19 | Brain-targeted polymersome codelivery of siRNA and temozolomide for effective glioblastoma chemo-RNAi synergistic therapy显示文摘Temozolomide (TMZ) is a clinically approved drug for glioblastoma (GBM) therapy. However, as a result of methylguanine-DNA-methyltransferase (MGMT), which is able to repair damaged DNA-damage repairing, TMZ usually yields unsatisfactory therapeutic effects. Small interfering RNA (siRNA) is a potential alteration tool for sensitivity of TMZ by targeting DNA repair enzymes. However, a suitable TMZ and siRNA codelivery system that can effectively and actively co-deliver siRNA/TMZ into the brain tumor is lacking. In this study, we constructed an angiopep-2 decorated polymersomal delivery system to co-deliver TMZ/siRNA for synergistic GBM therapy. This targeted polymersomal nanomedicine not only enhanced the circulation time of siRNA/TMZ in blood but also improved their blood-brain barrier (BBB) crossing and GBM targeting ability. Moreover, when we co-administered siRNAs specific to retinoblastoma binding protein 4 (RBBP4) together with TMZ in GBM cells, these RBBP4- specific siRNA (siRBBP4) modulated the sensitivity of TMZ by regulating MGMT, and thus showed a powerful synergistic anti-tumor effect. We demonstrated that angiopep-2 decorated polymersomal siRBBP4/TMZ co-loaded nanomedicines are capable of inhibiting tumor growth and significantly improved life expectancy of orthotropic GBM bearing mice. Overall, our study suggests that such a polymersomal TMZ/siRNA codelivery system provides a robust and potent nanoplatform for targeted GBM chemo-RNAi therapy. | Meng Zheng Chengnan Yan Qingshan Yang Feiyan Zhu Qiuli Du Xue Xia Marco Morsch Albert Lee Jinglong Yin Yan Zou Bingyang Shi | 2022 | ChemPhysMater2022,1,3: | 0 |
| 20 | Human Somatosensory Processing and Artificial Somatosensation显示文摘In the past few years,we have gained a better understanding of the information processing mechanism in the human brain,which has led to advances in artificial intelligence and humanoid robots.However,among the various sensory systems,studying the somatosensory system presents the greatest challenge.Here,we provide a comprehensive review of the human somatosensory system and its corresponding applications in artificial systems.Due to the uniqueness of the human hand in integrating receptor and actuator functions,we focused on the role of the somatosensory system in object recognition and action guidance.First,the low-threshold mechanoreceptors in the human skin and somatotopic organization principles along the ascending pathway,which are fundamental to artificial skin,were summarized.Second,we discuss high-level brain areas,which interacted with each other in the haptic object recognition.Based on this close-loop route,we used prosthetic upper limbs as an example to highlight the importance of somatosensory information.Finally,we present prospective research directions for human haptic perception,which could guide the development of artificial somatosensory systems. | Luyao Wang Lihua Ma Jiajia Yang Jinglong Wu | 2021 | Cyborg and Bionic Systems2021,,1: | 0 |