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| 1 | Regulation network and expression profiles of Epstein-Barr virus-encoded microRNAs and their potential target host genes in nasopharyngeal carcinomas显示文摘Epstein-Barr virus(EBV)is associated with nasopharyngeal carcinoma(NPC)tumorigenesis.However,the mechanism(s)connecting EBV infection and NPC remain unclear.Recently,a new class of EBV microRNAs(miRNAs)has been described.To determine how EBV miRNAs control the expression of host genes,and to understand their potential role in NPC tumorigenesis,we profiled the expression of 44 mature EBV miRNAs and potential host genes in NPC and non-tumor nasopharyngeal epithelial tissues.We found that 40 EBV miRNAs from the BART transcript were highly expressed in NPC.Analysis of potential BART miRNA target genes revealed that 3140 genes and several important pathways might be involved in the carcinogenesis of NPC.A total of 105 genes with potential EBV miRNA binding sites were significantly downregulated,suggesting that EBV miRNAs may regulate these genes and contribute to NPC carcinogenesis.An EBV miRNA and host gene regulation network was generated to provide useful clues for validating of EBV miRNA functions in NPC tumorigenesis. | ZENG ZhaoYang HUANG HongBin HUANG LiLi SUN MengXi YAN QiJia SONG YaLi WEI Fang BO Hao GONG ZhaoJian ZENG Yong LI Qiao ZHANG WenLing LI XiaYu XIANG Bo LI XiaoLing LI Yong XIONG Wei LI GuiYuan | 2014 | Science China(Life Sciences)2014，57，3： | 10 |
| 2 | Hydrographic field investigations in the Northern South China Sea by open cruises during 2004-2013显示文摘 | Lili Zeng Qiang Wang Qiang Xie Ping Shi Lei Yang Yeqiang Shu Ju Chen Dandan Sui Yunkai He Rongyu Chen Dongxiao Wang | 2015 | Science Bulletin2015，60，6： | 10 |
| 3 | Disturbance of hippocampal H2S generation contributes to CUMS-induced depression-like behavior: involvement in endoplasmic reticulum stress of hippocampus显示文摘长期的无法预言的温和压力淫液模型是消沉的一个广泛地使用的试验性的模型。在马头鱼尾的怪兽的外长的导致压力的 neuronal 房间死亡仔细与消沉的致病被联系。过多、延长的 endoplasmic 蜂窝胃嗯压力扳机房间死亡。氢硫化物 H 2 S,第三内长的发信号 gasotransmitter,作为 neuromodulator 和 neuroprotectant 在大脑功能起一个重要作用。我们假设了内长的 H 2 S 产生并且嗯在马头鱼尾的怪兽的应力可能涉及导致淫液的像消沉的行为。因此,集中于是否达到高潮的现在的学习扰乱内长的 H 2 S 和起来调整嗯在马头鱼尾的怪兽的应力并且是否外长的 H 2 S 阻止导致淫液的象压抑一样行为。结果证明对待淫液的老鼠展出像消沉的行为并且海马趾嗯包括调整葡萄糖的蛋白质的起来调整的层次的压力回答 78, CCAAT/enhancer 有约束力的蛋白质相应蛋白质,和劈开的 caspase-12 表示,当时 H 2 在马头鱼尾的怪兽的 S 在对待淫液的老鼠被压制。而且,外长的 H 2 S 阻止导致淫液的像消沉的行为。这些数据显示导致淫液的像消沉的行为与内长的 H 2 S 产生并且嗯在马头鱼尾的怪兽的应力并且建议了那内长的 H 2 S 并且嗯应力是消沉的新奇处理目标。 | Huiying Tan Wei Zou Jiamei Jiang Ying Tian Zhifang Xiao Lili Bi Haiying Zeng Xiaoqing Tang | 2015 | Acta Biochimica et Biophysica Sinica2015，47，4： | 8 |
| 4 | Contraceptive knowledge, attitudes and behavior about sexuality among college students in Beijing, China显示文摘 | ZHOU Hong WANG Xiao-ye YE Fang GU Hai-hua ZENG Xiao-pei lily WANG Yan | 2012 | Chinese Medical Journal2012，，6： | 8 |
| 5 | Vertically standing PtSe_2 film: a saturable absorber for a passively mode-locked Nd:LuVO_4 laser显示文摘The novel vertically standing Pt Se2 film on transparent quartz was prepared by selenization of platinum film deposited by the magnetron sputtering method, and an Nd:Lu VO4 passively mode-locked solid-state laser was realized by using the fabricated Pt Se2 film as a saturable absorber. The X-ray diffraction pattern and Raman spectrum of the film indicate its good crystallinity with a layered structure. The thickness of Pt Se2 film is measured to be 24 nm according to the cross-section height profile of the atomic force microscope image. Highresolution transmission electron microscopy images clearly demonstrate its vertically standing structure with an interlayer distance of 0.54 nm along the c-axis direction. The modulation depth(ΔT) and saturation fluence(Φs)of Pt Se2 film are measured to be 12.6% and 17.1 μJ∕cm2, respectively. The obtained mode-locked laser spectrum has a central wavelength of 1066.573 nm, with a 3 d B bandwidth of 0.106 nm. The transform limited pulse width of the mode-locked laser was calculated to be 15.8 ps. A maximum average output power of 180 m W with a working repetition rate of 61.3 MHz is obtained. To the best of our knowledge, this is the first report of the generation of ultrafast mode-locked laser pulses by using layered Pt Se2 as a saturable absorber. | LILI TAO XIAOWEN HUANG JUNSHAN HE YAJUN LOU LONGHUI ZENG YONGHUI LI HUI LONG JINGBO LI LING ZHANG YUEN HONG TSANG | 2018 | Photonics Research2018，6，7： | 8 |
| 6 | One-step synthesis of Fe-Ni hydroxide nanosheets derived from bimetallic foam for efficient electrocatalytic oxygen evolution and overall water splitting显示文摘The research of superior water oxidation electrodes is essential for the green energy in the form of hydrogen by way of electrolytic water splitting, and still remains challenging. Based upon dealloying foam, Fe-Ni hydroxide nanosheets network structure is designed on the surface of Fe-Ni alloy foam. The ratio of Ni/Fe elements was adjusted to realize the optimal catalytic activities for oxygen evolution reaction(OER) and hydrogen evolution reaction(HER). The obtained electrode of Fe-Ni hydroxide nanosheets/Fe-Ni alloy foam-60% Fe(FN LDH/FNF-60, 60 is the percentage of Fe content) possess low overpotential of 261 mV to reach 10 mA/cm^2, small Tafel slope(85.5 mV/dec), and superior long-term stability(remaining 10 mA/cm^2 for over 14 h without attenuation) toward OER in 1.0 mol/L KOH.Moreover, an alkaline water electrolyzer is constructed with the FN LDH/FNF-60 as anode and Ni(OH)_2/Fe-Ni alloy foam-25% Fe(Ni(OH)_2/FNF-25) as cathode, which displays superior electrolytic performance(affording 10 mA/cm^2 at 1.62 V) and lasting durability. | Lili Zeng Linjing Yang Jia Lu Jin Jia Jiayuan Yu Yunqie Deng Mingfei Shao Weijia Zhou | 2018 | Chinese Chemical Letters2018，29，12： | 7 |
| 7 | Involvement of CsWRKY70 in salicylic acid-induced citrus fruit resistance against Penicillium digitatum显示文摘Penicillium digitatum causes serious losses in postharvest citrus fruit.Exogenous salicylic acid(SA)can induce fruit resistance against various pathogens,but the mechanism remains unclear.Herein,a transcriptome-based approach was used to investigate the underlying mechanism of SA-induced citrus fruit resistance against P.digitatum.We found that CsWRKY70 and genes related to methyl salicylate(MeSA)biosynthesis(salicylate carboxymethyltransferase,SAMT)were induced by exogenous SA.Moreover,significant MeSA accumulation was detected in the SA-treated citrus fruit.The potential involvement of CsWRKY70 in regulating CsSAMT expression in citrus fruit was studied.Subcellular localization,dual luciferase,and electrophoretic mobility shift assays and an analysis of transient expression in fruit peel revealed that the nucleus‐localized transcriptional activator CsWRKY70 can activate the CsSAMT promoter by recognizing the W-box element.Taken together,the findings from this study offer new insights into the transcriptional regulatory mechanism of exogenous SA-induced disease resistance in Citrus sinensis fruit. | Bing Deng Wenjun Wang Changqing Ruan Lili Deng Shixiang Yao Kaifang Zeng | 2020 | Horticulture Research2020，7，1： | 6 |
| 8 | A water-evaporation-induced self-charging hybrid power unit for application in the Internet of Things显示文摘A self-charging hybrid power unit has been developed by integrating a water-evaporation-induced nano- generator with a flexible nano-patterned supercapacitor. The nanogenerator can harvest environmental thermal energy and mechanical energy through the water evaporation process, and the supercapacitor can be charged simultaneously. The former offers stable electrical power as output, whereas the Ppy- based supercapacitor shows a capacitance of 12.497 m F/cm^2 with 96.42% retention after 4,000 cycles. After filling the power unit with water as the fuel, it can be fully charged in about 20 min. The power unit can be flexibly integrated with electronic devices such as sensor nodes and wireless transmitters employ- ing the Internet of Things. This new approach can offer new possibilities in continuous future operation of randomly distributed electronic devices incorporated in the Internet of Things. | Haoxuan He Tianming Zhao Hongye Guan Tianyan Zhong Hui Zeng Lili Xing Yan Zhang Xinyu Xue | 2019 | Science Bulletin2019，64，19： | 5 |
| 9 | Whole Genome Analyses of Chinese Population and De Novo Assembly of A Northern Han Genome显示文摘To unravel the genetic mechanisms of disease and physiological traits,it requires comprehensive sequencing analysis of large sample size in Chinese populations.Here,we report the primary results of the Chinese Academy of Sciences Precision Medicine Initiative(CASPMI)project launched by the Chinese Academy of Sciences,including the de novo assembly of a northern Han reference genome(NH1.0)and whole genome analyses of 597 healthy people coming from most areas in China.Given the two existing reference genomes for Han Chinese(YH and HX1)were both from the south,we constructed NH1.0,a new reference genome from a northern individual,by combining the sequencing strategies of PacBio,10×Genomics,and Bionano mapping.Using this integrated approach,we obtained an N50 scaffold size of 46.63 Mb for the NH1.0 genome and performed a comparative genome analysis of NH1.0 with YH and HX1.In order to generate a genomic variation map of Chinese populations,we performed the whole-genome sequencing of 597 participants and identified 24.85 million(M)single nucleotide variants(SNVs),3.85 M small indels,and 106,382 structural variations.In the association analysis with collected phenotypes,we found that the T allele of rs1549293 in KAT8 significantly correlated with the waist circumference in northern Han males.Moreover,significant genetic diversity in MTHFR,TCN2,FADS1,and FADS2,which associate with circulating folate,vitamin B12,or lipid metabolism,was observed between northerners and southerners.Especially,for the homocysteine-increasing allele of rs1801133(MTHFR 677T),we hypothesize that there exists a “comfort”zone for a high frequency of 677T between latitudes of 35–45 degree North.Taken together,our results provide a high-quality northern Han reference genome and novel population-specific data sets of genetic variants for use in the personalized and precision medicine. | Zhenglin Du Liang Ma Hongzhu Qu Wei Chen Bing Zhang Xi Lu Weibo Zhai Xin Sheng Yongqiao Sun Wenjie Li Meng Lei Qiuhui Qi Na Yuan Shuo Shi Jingyao Zeng Jinyue Wang Yadong Yang Qi Liu Yaqiang Hong Lili Dong Zhewen Zhang Dong Zou Yanqing Wang Shuhui Song Fan Liu Xiangdong Fang Hua Chen Xin Liu Jingfa Xiao Changqing Zeng | 2019 | Genomics, Proteomics & Bioinformatics2019，17，3： | 4 |
| 10 | Admittance spectroscopy characterize graphite paste for back contact of CdTe thin film solar cells显示文摘CdTe thin film solar cells with a doped-graphite paste back contact layer were studied using admittance spectroscopy technology.The positions and the capture cross sections of energy level in the forbidden band were calculated,which are the important parameters to affect solar cell performance.The results showed that there were three defects in the CdTe thin films solar cells with the doped-graphite paste back contact layer,whose positions in the forbidden band were close to 0.34,0.46 and 0.51 eV,respectively above the valence band,and capture cross sections were 2.23×10-16,2.41×10-14,4.38×10-13 cm2,respectively. | HE XuLin,ZHANG JingQuan,FENG LiangHuan,WU LiLi,LI Wei,ZENG GuangGen,LEI Zhi,LI Bing & ZHENG JiaGui College of Materials Science and Engineering,Sichuan University,Chengdu 610064,China | 2010 | Science China(Technological Sciences)2010，53，9： | 4 |
| 11 | Effect of Thermal Cycling on Properties and Microstructure of SnAgCuCe Soldered Joints in QFP Devices显示文摘Increasing global concern about the environment is bringing regulatory (European directives) and consumer ('green products') pressure on the electronics industry in Europe and Japan to reduce or completely eliminate the use of lead (Pb) in products. Among all lead-free solder alloys, SnAgCu solder system, which has better thermo-mechanical properties compared with those of SnPb solder, is proven to be one of the promising candidates for electronic assembly. Previous work also revealed that adding a small amount of rare earth Ce into SnAgCu solder can visibly improve the properties and inhibit the excessive growth of the intermetallic compound layer. Thermal fatigue properties of SnAgCuCe soldered joints in QFP devices under thermal conditions have been investigated by finite element method and experiments. Based on creep model of low stress and high stress, corresponding creep subroutine was established for simulating the stress and strain response of SnAgCuCe soldered joint from -55 ℃ to 125 ℃, and fatigue life was calculated using creep fatigue life prediction equation. Moreover, thermal cycling experiments were conducted, the experimental results were found to be close to the simulated results. In addition, the tensile force of SnAgCuCe soldered joints decreased with increasing number of thermal cycles, and the fracture mechanism transformed from toughness fracture to brittle intergranular fracture. Moreover the tensile force changes and fracture microstructure evolution could benefit the quantitative evaluations of the mechanical performances of lead-free soldered joints under thermal cycling loadings. | ZHANG Liang XUE Songbai GAO Lili ZENG Guang YU Shenglin SHENG Zhong | 2011 | Chinese Journal of Mechanical Engineering2011，24，4： | 4 |
| 12 | eGPS 1.0: comprehensive software for multi-omic and evolutionary analyses显示文摘It has become increasingly challenging for researchers to analyze the exponentially expanding amount of multi-omic data.Here,we describe multi-functional software named evolutionary GenotypePhenotype Systems(eGPS)that enables users to perform comprehensive multiomic and evolutionary analyses.The eGPS combines the power of cloud computing and the advantage of desktop application,has a user-friendly graphic interface and is highly interactive. | Dalang Yu Lili Dong Fangqi Yan Hailong Mu Bixia Tang Xiao Yang Tao Zeng Qing Zhou Feng Gao Zhonghuang Wang Ziqian Hao Hongen Kang Yi Zheng Hongwei Huang Yuzhang Wei Wei Pan Yaochen Xu Junwei Zhu Shilei Zhao Ciran Wang Pengyu Wang Long Dai Mushan Li Li Lan Yiwei Wang Hua Chen Yi-Xue Li Yun-Xin Fu Zhen Shao Yiming Bao Fangqing Zhao Luo-Nan Chen Guo-Qing Zhang Wenming Zhao Haipeng Li | 2019 | National Science Review2019，6，5： | 4 |
| 13 | The Global Landscape of SARS-CoV-2 Genomes, Variants, and Haplotypes in 2019nCoVR显示文摘On January 22,2020,China National Center for Bioinformation(CNCB)released the 2019 Novel Coronavirus Resource(2019nCoVR),an open-access information resource for the severe acute respiratory syndrome coronavirus 2(SARS-CoV-2).2019nCoVR features a comprehensive integration of sequence and clinical information for all publicly available SARS-CoV-2 isolates,which are manually curated with value-added annotations and quality evaluated by an automated in-house pipeline.Of particular note,2019nCoVR offers systematic analyses to generate a dynamic landscape of SARS-CoV-2 genomic variations at a global scale.It provides all identified variants and their detailed statistics for each virus isolate,and congregates the quality score,functional annotation,and population frequency for each variant.Spatiotemporal change for each variant can be visualized and historical viral haplotype network maps for the course of the outbreak are also generated based on all complete and high-quality genomes available.Moreover,2019nCoVR provides a full collection of SARS-CoV-2 relevant literature on the coronavirus disease 2019(COVID-19),including published papers from PubMed as well as preprints from services such as bioRxiv and medRxiv through Europe PMC.Furthermore,by linking with relevant databases in CNCB,2019nCoVR offers data submission services for raw sequence reads and assembled genomes,and data sharing with NCBI.Collectively,SARS-CoV-2 is updated daily to collect the latest information on genome sequences,variants,haplotypes,and literature for a timely reflection,making 2019nCoVR a valuable resource for the global research community.2019nCoVR is accessible at http://gffzzdbc7b6aaae734bddscuk596uk09uq69wo.ffgz.tsg.suse.edu.cn/ncov/. | Shuhui Song Lina Ma Dong Zou Dongmei Tian Cuiping Li Junwei Zhu Meili Chen Anke Wang Yingke Ma Mengwei Li Xufei Teng Ying Cui Guangya Duan Mochen Zhang Tong Jin Chengmin Shi Zhenglin Du Yadong Zhang Chuandong Liu Rujiao Li Jingyao Zeng Lili Hao Shuai Jiang Hua Chen Dali Han Jingfa Xiao Zhang Zhang Wenming Zhao Yongbiao Xue Yiming Bao | 2020 | Genomics, Proteomics & Bioinformatics2020，18，6： | 4 |
| 14 | Pakl mediates the stimulatory effect of insulin and curcumin on hepatic ChREBP expression显示文摘 | Kejing Zeng Lili Tian Adam Sirek Weijuan Shao Ling Liu Yu-Ting Chiang Jonathan Chernoff Dominic S. Ng Jianping Weng Tianru Jin | 2017 | Journal of Molecular Cell Biology2017，9，5： | 4 |
| 15 | Distribution of living radiolarians in spring in the South China Sea and its responses to environmental factors显示文摘Using a planktonic net(62-?m mesh) and a Rose-Bengal staining method, we studied the spatial distribution of living radiolarians in spring along two sections of the South China Sea(SCS) in spring and discussed the responses of living radiolarian distribution to tropical environmental factors. Generally, the highest abundance of living radiolarians occurred at the depth range of 25–75 m, where the chlorophyll-a maximum and the highest primary productivity were. In contrast, the maximum living abundance occurred in the top 25 m in cold eddies in the open seas and the abundance decreased with depth. We found that the inhibition effect of changing salinity(due to runoffs) on living radiolarians was much stronger than the promotion effect of mesoscale cold eddies. We observed that large variation of temperature was unfavorable for living radiolarians. The dominant species composition consisted of tropical-subtropical warm species. We identified some indicator species for tropical environments. Living Didymocyrtis tetrathalamus tetrathalamus could be an indicator for tropical surface water or mixed-layer water, and even for tropical oligotrophic water. Living Tetrapyle octacantha could be used to indicate tropical thermocline and eutrophic environment. Living Acanthodesmia vinculata could indicate tropical surface and subsurface waters. T. octacantha and A. vinculata should only be used as indicators for upwelling in the open seas, i.e., far away from river mouths. Living Siphonosphaera polysiphonia preferred to form colonies, which might be related to the effect of warm eddies. Living Cyrtopera laguncula and living Cornutella profunda occurred in the tropical upper layer, even in the surface layer, which suggests that they should not be used as indicators for intermediate and deep waters. | HU WeiFen ZHANG LanLan CHEN MuHong ZENG LiLi ZHOU WeiHua XIANG Rong ZHANG Qiang LIU ShiHao | 2015 | Science China Earth Sciences2015，58，2： | 4 |
| 16 | LA-ICP-MS U–Pb geochronology of detrital zircons from the Zhaochigou Formation-complex in the Helan Mountain and its tectonic significance显示文摘This paper carries out studies about LA-ICPMS U–Pb dating and Hf isotopic compositional analysis for detrital zircons in two metasedimentary samples that were taken from the Zhaochigou Formation-complex in the Helan Mountain.The results show that the Zhaochigou Formation-complex formed*1.96 Ga,and it is a part of the Khondalite Series that is widespread in the North China Craton(NCC).The age spectrum of the detrital zircons indicates that the Zhaochigou Formation-complex shared the same provenance with the eastern edge of the Khondalite Series.Products of ancient magmatic activities within the Khondalite Belt may be the major source for the sedimentary materials that formed the Khondalite Series.Our age-dating results suggest that the Khondalite Series in the NCC may have experienced two stages of metamorphism,as the early stage occurred during 1.96–1.95 Ga,and the later stage occurred at about 1.87 Ga.The Hfisotopic data indicate that the Western Block of the NCC endured a stage of crustal growth at 2.5–2.3 Ga. | Liming Li Zuoxun Zeng Yanjun Lu Yunxu Wei Shimin Xiang Lili Pan | 2014 | Chinese Science Bulletin2014，59，13： | 3 |
| 17 | Impacts of a wind stress and a buoyancy flux on the seasonal variation of mixing layer depth in the South China Sea显示文摘The seasonal variation of mixing layer depth(MLD) in the ocean is determined by a wind stress and a buoyance flux.A South China Sea(SCS) ocean data assimilation system is used to analyze the seasonal cycle of its MLD.It is found that the variability of MLD in the SCS is shallow in summer and deep in winter,as is the case in general.Owing to local atmosphere forcing and ocean dynamics,the seasonal variability shows a regional characteristic in the SCS.In the northern SCS,the MLD is shallow in summer and deep in winter,affected coherently by the wind stress and the buoyance flux.The variation of MLD in the west is close to that in the central SCS,influenced by the advection of strong western boundary currents.The eastern SCS presents an annual cycle,which is deep in summer and shallow in winter,primarily impacted by a heat flux on the air-sea interface.So regional characteristic needs to be cared in the analysis about the MLD of SCS. | XIAO Xianjun WANG Dongxiao ZHOU Wen ZHANG Zuqiang QIN Yinghao HE Na ZENG Lili | 2013 | Acta Oceanologica Sinica2013，32，9： | 3 |
| 18 | DNA Nanotechnology Mediated Gold Nanoparticle Conjugates and Their Applications in Biomedicine显示文摘金 nanoparticles (Au NP ) 向众多的生物医学的应用提供唯一的化学、物理的性质。Au NP 能乐意地被综合,并且与多重化学或生物的分子修改了,在 vitro 并且在 vivo 成像,药交货和催化作用,使他们成为生物传感器的优秀候选人。完美的特定的 DNA 基础配对当基因信息搬运人而且构造小说 nanostructures 和混血儿与象 Au NP 那样的无机的 nanomaterials 结合,不能仅仅服务。有象控制函数一样的精确直径和可编程的序列,有明确的尺寸的各种各样的 DNA 静态的 nanostructures,形状和动态结构的一方面,基于包括无匹的底的唯一的 DNA 字符配对的、双螺旋直用 DNA 纳米技术被创造了。在另一方面,在纳米技术和 nanoscience 的快速的开发有 DNA 和 DNA 结构怎么与无机的 nanomaterials 交往的新问题,它应该为他们的生物、生物医学的应用是重要的。在这评论,我们打算在基于 NPs 的 DNA 为生物医学的应用结合的最近的先进 Au 上提供概述,主要包括 Au NP 的 functionalization (Au 基于 NPs 的 DNA 结合与 Au-S 债券或 Au-polyA 交往) ;Au 的申请基于 NPs 在 biomedicine 结合药交货和治疗,和 Au NPs-DNA 例如 biosensing,结合基于的先进 nanostructures。 | ChenguangWang Huan Zhang Dongdong Zeng Lili San Xianqiang Mi | 2016 | Chinese Journal of Chemistry2016，34，3： | 2 |
| 19 | Contrasting dynamic characteristics of shear turbulence and Langmuir circulation in the surface mixed layer显示文摘Large eddy simulation(LES) is used to investigate contrasting dynamic characteristics of shear turbulence(ST)and Langmuir circulation(LC) in the surface mixed layer(SML). ST is usually induced by wind forcing in SML. LC can be driven by wave-current interaction that includes the roles of wind, wave and vortex forcing. The LES results show that LC suppresses the horizontal velocity and greatly modifies the downwind velocity profile, but increases the vertical velocity. The strong downwelling jets of LC accelerate and increase the downward transport of energy as compared to ST. The vertical eddy viscosity Km of LC is much larger than that of ST. Strong mixing induced by LC has two locations. They are located in the 2ds–3ds(Stokes depth scale) and the lower layer of the SML,respectively. Its value and position change periodically with time. In contrast, maximum Km induced by ST is located in the middle depth of the SML. The turbulent kinetic energy(TKE) generated by LC is larger than that by ST. The differences in vertical distributions of TKE and Km are evident. Therefore, the parameterization of LC cannot be solely based on TKE. For deep SML, the convection of large-scale eddies in LC plays a main role in downward transport of energy and LC can induce stronger velocity shear(S2) near the SML base. In addition, the large-scale eddies and S2 induced by LC is changing all the time, which needs to be fully considered in the parameterization of LC. | LI Guojing WANG Dongxiao CHEN Ju YAO Jinglong ZENG Lili SHU Yeqiang SUI Dandan | 2015 | Acta Oceanologica Sinica2015，34，5： | 2 |
| 20 | WRKY33-mediated indolic glucosinolate metabolic pathway confers resistance against Alternaria brassicicola in Arabidopsis and Brassica crops显示文摘The tryptophan(Trp)-derived plant secondary metabolites,including camalexin,4-hydroxyindole-3-carbonylnitrile,and indolic glucosinolate(IGS),show broad-spectrum antifungal activity.However,the distinct regulations of these metabolic pathways among different plant species in response to fungus infection are rarely studied.In this study,our results revealed that WRKY33 directly regulates IGS biosynthesis,notably the production of 4-methoxyindole-3-ylmethyl glucosinolate(4MI3G),conferring resistance to Alternaria brassicicola,an important pathogen which causes black spot in Brassica crops.WRKY33 directly activates the expression of CYP81F2,IGMT1,and IGMT2 to drive sidechain modification of indole-3-ylmethyl glucosinolate(I3G)to 4MI3G,in both Arabidopsis and Chinese kale(Brassica oleracea var.alboglabra Bailey).However,Chinese kale showed a more severe symptom than Arabidopsis when infected by Alternaria brassicicola.Comparative analyses of the origin and evolution of Trp metabolism indicate that the loss of camalexin biosynthesis in Brassica crops during evolution might attenuate the resistance of crops to Alternaria brassicicola.As a result,the IGS metabolic pathway mediated by WRKY33 becomes essential for Chinese kale to deter Alternaria brassicicola.Our results highlight the differential regulation of Trp-derived camalexin and IGS biosynthetic pathways in plant immunity between Arabidopsis and Brassica crops. | Han Tao Huiying Miao Lili Chen Mengyu Wang Chuchu Xia Wei Zeng Bo Sun Fen Zhang Shuqun Zhang Chuanyou Li Qiaomei Wang | 2022 | Journal of Integrative Plant Biology2022，64，5： | 2 |
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