|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Dynamic chromatin states in human ES cells reveal potential regulatory sequences and genes involved in pluripotency显示文摘Pluripotency,一个细胞的能力区分并且产生所有胚胎的系,定义象胚胎的茎(ES ) 那样的哺乳动物的细胞类型的一个小数字细胞。当它通常被保持了时,那 pluripotency 是 transcriptional 的产品激活并且维持关键干细胞基因的表达式的规章的网络,积累的证据在建立并且保卫 ES 房间的 pluripotency 为 epigenetic 进程正在指向一个关键角色,象维持区分的房间类型的身份一样。以便更好在 pluripotency 理解 epigenetic 机制的角色,我们检验了在经历区别进一个 mesendodermal 系的人的 ES 房间(hESCs ) 染色体宽的染色质修正的动力学。我们发现在倡导者的染色质修正在区别期间仍然保持大部分不变,除了在在在 H3K27 的 acetylation 和 methylation 之间的一个动态开关标记在基因表示的激活和 silencing 之间的转变的倡导者的一个小数字,建议在在大多数差别上的房间命运承诺的一个层次表示了基因。我们也在 50 000 潜在的 enhancers 上印射,并且在染色质修正,特别 H3K4me1 和 H3K27ac 观察了大得多的动力学,它与他们的潜在的目标基因的表示相关。这些 enhancers 的进一步的分析揭示了 pluripotency 和可以在 hESCs 授与发展胜任的一个平衡状态的一口染色质签名陈述语气的潜在地关键的 transcriptional 管理者。我们的结果提供在定义 enhancers 和 pluripotency 支持染色质修正的角色的新证据。 | R David Hawkins Gary C Hon Chuhu Yang Jessica E Antosiewicz-Bourget Leonard K Lee Que-Minh Ngo Sarit Klugman Keith A Ching Lee E Edsall Zhen Ye Samantha Kuan Pengzhi Yu Hui Liu Xinmin Zhang Roland D Green Victor V Lobanenkov Ron Stewart James A Thomson Bing Ren | 2011 | Cell Research2011，21，10： | 6 |
| 2 | Muscle force and movement variability before and after total knee arthroplasty: A review显示文摘Variability in muscle force output and movement variability are important aspects of identifying individuals with mobility deficits, central nervous system impairments, and future risk of falling. This has been investigated in elderly healthy and impaired adults, as well as in adults with osteoarthritis(OA), but the question of whether the same correlations also apply to those who have undergone a surgical intervention such as total knee arthroplasty(TKA) is still being investigated. While there is a growing body of literature identifying potential rehabilitation targets for individuals who have undergone TKA, it is important to first understand the underlying post-operative impairments to more efficiently target functional deficits that may lead to improvedlong-term outcomes. The purpose of this article is to review the potential role of muscle force output and movement variability in TKA recipients. The narrative review relies on existing literature in elderly healthy and impaired individuals, as well as in those with OA before and following TKA. The variables that may predict longterm functional abilities and deficits are discussed in the context of existing literature in healthy older adults and older adults with OA and following TKA, as well as the role future research in this field may play in providing evidence-based data for improved rehabilitation targets. | Jessica W Smith Jesse C Christensen Robin L Marcus Paul C LaStayo | 2014 | World Journal of Orthopedics2014，5，2： | 3 |
| 3 | 由地震简正模式观测得到的内核各向异性区域变化显示文摘地球的固体内核被对流的液体外核包围,由此创建了驱动地球磁场的地核发电机。用压缩体波研究地震显示出内核各向异性结构的半球性变化,但由于受地震和接收器分布状况所限,这一结论还不够充分。本文中,利用大地震的简正模式分裂函数测定结果,并基于扩展交叉耦合理论,我们观测到了区域变化和内核中东、西两半球的各向异性。这一模式与地球磁场的相似性说明在固化或组构演变过程中由Maxwell应力引起的晶体排列的凝入是产生各向异性的根源。这些观测结果限制了内核超速旋转的总量,但与振荡相符。 | Arwen Deuss Jessica C E Irving John H Woodhouse 洪启宇(译) 左玉玲(校) | 2010 | 国际地震动态2010，，10： | 2 |
| 4 | Novel Brφ nsted acidic ionic liquids and their use as dualsolventcatalysts显示文摘 | Amanda C Cole Jessica L Ioanna Ntai | 2002 | J Am Chem Soc2002，124，： | 1 |
| 5 | Nicotine reduce A β in the brain and cerebral vessels of APPsw mice显示文摘 | Ewa HL Jennifer C Jessica K | 2004 | Eur J Neurosci2004，19，： | 1 |
| 6 | A point mutation in a Drosophila GABA receptor confers insecticide resistance 显示文摘 | Ffrench-Constant Richard H Rocheleau Thomas A Steichen Jessica C Chalmers Alison E | 1993 | Nature (London)1993，363，： | 1 |
| 7 | CAI inhibits the growth of small cell lung cancer cells显示文摘 | Terry W Moody Jessica Chiles Elizabeth Moody Gregory J Sieczkiewicz Elise C Kohn | 2003 | Lung Cancer2003，，3： | 1 |
| 8 | Preschooler's physical activity levels and associations with lesson context,teacher's behavior,and environment during preschool physical education显示文摘 | Van Cauwenberghe E Valery L Jessica G Ilse D B Greet C | 2012 | Early Childhood Research Quarterly2012，27，2： | 1 |
| 9 | Novel bronsted acidic ionic liquids and their use as dual solvent catalysts 显示文摘 | Cole Amanda C Jensen Jessica L Ntai ioarma | 2002 | J Am Chem Soc2002，124，21： | 1 |
| 10 | Recovery of valuable elements from spent Li-batteries 显示文摘 | JESSICA F P NATALIA G B JLrLIO C A | 2008 | Journal of Hazardous Materi- als2008，150，： | 1 |
| 11 | Genome sequence of the palaeopolyploid soybean 显示文摘 | Jeremy S Steven B C Jessica S | 2010 | Nature2010，463，： | 1 |
| 12 | Novel Bronsted acidic ionic liquids and their use as dual solvent-catalysts显示文摘 | AMANDA C C JESSICA L J LOANNA N | 2002 | J Am Chem Soc2002，124，21： | 1 |
| 13 | Phytotherapy management:a new intervention for nursing intervention classification显示文摘 | Paloma E Ovidio C Jessica R | 2014 | Holist Nurs Pract2014，28，6： | 1 |
| 14 | Metformin therapy in a transgenic mouse model of Huntington's disease 显示文摘 | THONG C M JESSICA L B BENJAMIN O | 2007 | Neurosci Lett2007，411，2： | 1 |
| 15 | Psychotropic drug interactions with valproate显示文摘 | Jessica F Manoranjenni C | 2005 | Clin Neuropharmacol2005，28，2： | 1 |
| 16 | Short-term sprint interval training inereases insulin sensitivity in healthy adults but does not affeet the thermogenie response to β-adrenergie stimulation 显示文摘 | Jennifer C Richards Tyler K Johnson Jessica N Kuzma | 2010 | The Journal of Physiology2010，588，15： | 1 |
| 17 | Combining quality andantioxidant attributes in the strawberry: the role of geno- type 显示文摘 | Franco C Jessica S Bruno M | 2008 | Food Chemistry2008，111，： | 1 |
| 18 | Systematic comparison of perfusion-CT and CT angiography in acute stroke patients显示文摘 | Jessica C T William P D Songling L | 2007 | Ann Neurol2007，61，6： | 1 |
| 19 | Relative roles of the cellular and humoral responses in the Drosophila host de- fense against three Gram-positive bacterial infections 显示文摘 | Nadine T N Jessica Q Ju H C | 2011 | PLoS One2011，6，3： | 1 |
| 20 | Advanced glycation end product ligands for the receptor for advanced glycation end products: biochemical characterization and formation kinetics显示文摘 | Jessica V Valencia Stephen C Weldon Douglas Quinn Geesje H Kiers Jeroen DeGroot Johan M TeKoppele Thomas E Hughes | 2003 | Analytical Biochemistry2003，，1： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员