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37篇 您的检索式:作者名="Isaacs MA"
    题名 作者 年代 出处 被引量
1医学分子生物学CRISPR基因编辑与社会法规的进步与完善显示文摘利用CRISPR基因技术体系进行精密编辑,标志着人类攻克遗传疾病在理论上已进入新阶段,临床应用已有了实质性的突破,对促进人类健康和社会的和谐具有重大意义。本文对该技术在临床的应用、社会影响、西方国家对该技术社会伦理道德的界定和法律法规的发展,以及CRISPR精密编辑技术对科研与社会伦理道德范畴的精细化进行了探讨。CRISPR在生殖生物学领域的应用,将导致生物医学领域发生社会发展的重大变革。CRISPR精准基因编辑和干细胞技术的巨大科研前景和商业价值,可能会带来一系列的问题。CRISPR基因精密编辑在生物医学中的应用对社会、对各级医疗机构、医学院校和研究机构均有重要的影响,卫生主管部门应借鉴国际上相关做法,制定科学研究伦理道德的相关政策法规,使中国在医学分子生物学领域作出应有的贡献。杨蓉 梁瑜 于秋霞 吴亚君 雷新娟 孙渝婷 王丹 张伟 周鑫 李忠光 王李阳 MengMeng Xu William Isaacs Jianjie Ma 徐学红 2019医学与社会2019,32,6:3
2Adenomatoid tu-mors of the uterus:an analysis of 60 cases显示文摘Nogales FF Isaac MA Hardisson D 0,,01:1
3Glial growth factor restricts mammalian neural crest stem cells to a glial fate 显示文摘 Marchionni MA Isaacs I 1994Cell1994,77,3:1
4Cytomegalovirus antiviral resistance associated with treatment induced UL97 (protein kinase) and UL54 (DNA polymerase) mutations显示文摘Scott GM Isaacs MA Zeng F 2004J Med Virol2004,74,1:1
5Cytomegalovirus antiviral resistance associated with treatment induced UL97 (protein kinase) and UL54 (DNA polymerase)mutations显示文摘Scott GM Isaacs MA Zeng F 2004J Med Virol2004,74,1:1
6Prognos-tic factors in open globe injuries 显示文摘Crnvinel Isaac DL Ghanem VC Nascimento MA 2003Ophthalmologica2003,217,:1
7Adenomatoid tumors of the uterus:an analysis of 60 cases显示文摘Nogales FF Isaac MA Hardisson D 2002Int J Gynecol Pathol2002,21,:1
8Glial growth factor restricts mammalian neural crest stem cells to a glial fate显示文摘Shah NM Marchionni MA Isaacs I 1994Cell1994,77,3:1
9Gllal growth factor restricts mammalian neural crest stem cells to a glial fate显示文摘Shah NM Marchionni MA Isaacs I 1994Cell1994,77,:1
10Glial growth factor restricts mammalian neural crest stem cells to a glial fate显示文摘Sham NM Marchionni MA Isaacs I 1994Cell1994,77,:1
11Adenomatoid tumors of the uterus:an analysis of 60 cases显示文摘Nogales FF Isaac MA Hardisson D 2002Int J Gynecol Pathol2002,21,1:1
12Management of craniopharyngioma 显示文摘Isaac MA Hahn SS Kim JA 2001Cancer J2001,7,6:1
13Adenomatoid tumors of the uterus:an analysis of 60 cases显示文摘Francisco FF Isaac MA Hardisson D 2002Int J Gynecol Pathol2002,21,:1
14Adenomatoid Tumors of the Uterus : An Analysis of 60 Cases 显示文摘Nogales FF Isaac MA Hardisson D 2002International Journal of Gy- necological Pathology2002,21,:1
15Glial growth factor restricts mammalian neural crest stem cells to a glial fate显示文摘Shah NM Marchionni MA Isaacs I 1994Cell1994,677,3:1
16Neuropsyehological development of behavior attributed to frontal lobe functioning in children显示文摘Passler MA Isaac W Hynd GW 1985Developmental Neuropsychology1985,1,:1
17Functioning uterine sex cord tumour显示文摘Nogales FF Isaac MA 2002Histopathology2002,41,3:1
18Untargeted UPLC- MS profiling pipeline to expand tissue metabolome cov- erage:application to cardiovascular disease 显示文摘Vorkas PA Isaac G Anwar MA 2015Anal Chem2015,87,8:1
19Adenomatoid tumors of the uterus:an analysis of 60 cases显示文摘Nogales FF Isaac MA Hardisson D 2002Int J Gynecol Pathol2002,21,1:1
20Copy number analysis indicates monoclonal origin of lethal metastatic prostate cancer显示文摘Liu WN Laitinen S Khan S Vihinen M Kowalski J Yu GQ Chen L Ewing CM Eisenberger MA Carducci MA Nelson WG Yegnasubramanian S Luo J Wang Y Xu JF Isaacs WB Visakorpi T Bova GS 0,,05:1
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