|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Peritoneal carcinomatosis of colorectal origin:Incidence,prognosis and treatment options显示文摘Peritoneal carcinomatosis (PC) is one manifestation of metastatic colorectal cancer (CRC). Tumor growth on intestinal surfaces and associated fluid accumulation eventually result in bowel obstruction and incapacitating levels of ascites, which profoundly affect the quality of life for affected patients. PC appears resistant to traditional 5-fluorouracil-based chemotherapy, and surgery was formerly reserved for palliative purposes only. In the absence of effective treatment, the histori-cal prognosis for these patients was extremely poor, with an invariably fatal outcome. These poor outcomes likely explain why PC secondary to CRC has received little attention from oncologic researchers. Thus, data are lacking regarding incidence, clinical disease course, and accurate treatment evaluation for patients with PC. Recently, population-based studies have revealed that PC occurs relatively frequently among patients withCRC. Risk factors for developing PC have been identi-fied:right-sided tumor, advanced T-stage, advanced N-stage, poor differentiation grade, and younger age at diagnosis. During the past decade, both chemother-apeutical and surgical treatments have achieved prom-ising results in these patients. A chance for long-term survival or even cure may now be offered to selected patients by combining radical surgical resection with intraperitoneal instillation of heated chemotherapy. This combined procedure has become known as hy-perthermic intraperitoneal chemotherapy. This edito-rial outlines recent advancements in the medical and surgical treatment of PC and reviews the most recent information on incidence and prognosis of this disease. Given recent progress, treatment should now be considered in every patient presenting with PC. | Yvonne LB Klaver Valery EPP Lemmens Simon W Nienhuijs Misha DP Luyer Ignace HJT de Hingh | 2012 | World Journal of Gastroenterology2012，18，39： | 9 |
| 2 | Challenges in diagnosing adhesive small bowel obstruction显示文摘Adhesive small bowel obstruction(ASBO)is the most frequently encountered surgical disorder of the small intestine.Up to 80%of ASBO cases resolve spontaneously and do not require invasive treatment.It is important to identify such patients that will benefit from conservative treatment in order to prevent unnecessarily exposing them to the risks associated with surgical intervention,such as morbidity and further adhesion formation.For the remaining ASBO patients,timely surgical intervention is necessary to prevent small bowel strangulation,which may cause intestinal ischemia and bowel necrosis.While early identification of these patients is key to decreasing ASBO-related morbidity and mortality,the non-specific signs and laboratory findings upon clinic presentation limit timely diagnosis and implementation of appropriate clinical management.Combining the clinical presentation findings with those from other diagnostic imaging modalities,such as abdominal X-ray,computed tomography-scan and water-soluble contrast studies,will improve diagnosis of ASBO and help clinicians to better evaluate the potential of conservative management as a safe strategy for a particular patient.Nonetheless,patients who present with moderate findings by all these approaches continue to represent a challenge.A new diagnostic strategy is urgently needed to further improve our ability to identify early signs of strangulated bowel,and this diagnostic modality should be able to indicate when surgical management is required.A number of potential serum markers have been proposed for this purpose,including intestinal fatty acid binding protein andα-glutathione S transferase.On-going research is attempting to clearly define their diagnostic utility and to optimize their potential role in determining which patients should be managed surgically. | Thijs R van Oudheusden Bart AC Aerts Ignace HJT de Hingh Misha DP Luyer | 2013 | World Journal of Gastroenterology2013，19，43： | 7 |
| 3 | Giant cystic lymphangioma originating from the lesser curvature of the stomach显示文摘Cystic lymphangiomas are rare benign tumors.Most frequently occurring in children and involving the neck or axilla,these tumors are much less common in adults and very rarely involve the abdomen.The known congenital and acquired(traumatic)etiologies result in failure of the lymphatic channels and consequent proliferation of lymphatic spaces.This case report describes a very rare case of a giant mesenteric cystic lymphangioma in an adult male with no clear etiology and successful resolution by standard radical resection.A previously healthy 44-year-old male presented with a 6-wk history of progressive upper abdominal pain,vomiting,anorexia and unintentional weight loss accompanied by rapid abdominal distension.A palpable mass was detected upon physical examination of the distended abdomen and abdominal computed tomography scan showed a giant multilobulated cystic process,measuring 40 cm in diameter.Exploratory laparotomy revealed an enormous cystic mass containing 6 L of serous fluid.The process appeared to originate from the lesser omentum and the lesser curvature of the stomach.Radical resection of the tumor was performed along with a partial gastrectomy to address potential invasion into the adjacent tissues.Histological analysis confirmed the diagnosis of a multicystic lymphangioma.The postoperative recovery was uneventful and the patient was discharged after 6 d.At 3-mo follow-up,the patient was in good health with no signs of recurrence. | Thijs Ralf van Oudheusden Simon Willem Nienhuijs Thomas Bernard Joseph Demeyere Michael Derek Philip Luyer Ignace Hubertus Johannes Theodorus de Hingh | 2013 | World Journal of Gastrointestinal Surgery2013，5，10： | 3 |
| 4 | Cytoreduction and HIPEC in The Netherlands: Nationwide Long-term Outcome Following the Dutch Protocol显示文摘 | Anke M. J. Kuijpers Boj Mirck Arend G. J. Aalbers Simon W. Nienhuijs Ignace H. J. T. Hingh Martinus J. Wiezer Bert Ramshorst Robert J. Ginkel Klaas Havenga Andreas J. Bremers Johannes H. W. Wilt Elisabeth A. Velde Vic J. Verwaal | 2013 | Annals of Surgical Oncology2013，，13： | 2 |
| 5 | Reduction of Postoperative Ileus by Early Enteral Nutrition in Patients Undergoing Major Rectal Surgery: Prospective, Randomized, Controlled Trial显示文摘 | Petra G. Boelens Fanny F. B. M. Heesakkers Misha D. P. Luyer Kevin W. Y. van Barneveld Ignace H. J. T. de Hingh Grard A. P. Nieuwenhuijzen Arnout N. Roos Harm J. T. Rutten | 2014 | Annals of Surgery2014，，4： | 2 |
| 6 | Outcomes of colorectal cancer patients with peritoneal carcinomatosis treated with chemotherapy with and without targeted therapy显示文摘 | Y.L.B. Klaver L.H.J. Simkens V.E.P.P. Lemmens M. Koopman S. Teerenstra R.P. Bleichrodt I.H.J.T. de Hingh C.J.A. Punt | 2012 | European Journal of Surgical Oncology2012，，7： | 2 |
| 7 | Respiratory distress due to malignant ascites palliated by hyperthermic intraperitoneal chemotherapy显示文摘Malignant ascites is a common symptom in patients with peritoneal cancer. Current assumption is that anincreased vascular permeability and obstruction of lymphatic channels lead to the accumulation of fluid in the abdominal cavity. This case report describes a severely symptomatic patient with malignant ascites. The previously healthy 73-year-old male was presented with abdominal distention causing respiratory distress. Computed tomography revealed large amounts of ascites, a recto-sigmoidal mass with locoregional lymphadenopathy and an omental cake. Biopsy taken during colonoscopy revealed an adenocarcinoma of the colon with signet cell differentiation. A widespread peritoneal carcinomatosis was found during a diagnostic laparoscopy. The extent of peritoneal disease rendered the patient not suitable for cytoreductive surgery with curative intent. The ascites proved to be refractory to ultrasound-guided paracentesis; thus, a decision was made to perform palliative hyperthermic intraperitoneal chemotherapy without cytoreductive surgery. Consequently, ascites production stopped, and the respiratory distress was relieved thereafter. The postoperative recovery was uneventful. Ascites recurred eight months later, and a second hyperthermic intraperitoneal chemotherapy procedure was performed. The patient was still alive at the time of writing, 16 mo after the initial diagnosis. | Marijn Marinus Leonardus van den Houten Thijs Ralf van Oudheusden Michael Derek Philip Luyer Simon Willem Nienhuijs Ignace Hubertus Johannes Theodorus de Hingh | 2015 | World Journal of Gastrointestinal Surgery2015，7，3： | 1 |
| 8 | Laparoscopic parastomal hernia repair using a keyhole technique results in a high recurrence rate显示文摘 | Hansson BM Bleichrodt RP de Hingh IH | 2009 | Surg Endosc2009，23，7： | 1 |
| 9 | Laparoscopic parastomal hernia repair is feasible and safe: early results of a prospective clinical study including 55 consecutive patients显示文摘 | B. M. E. Hansson I. H. J. T. Hingh R. P. Bleichrodt | 2007 | Surgical Endoscopy2007，，6： | 1 |
| 10 | Laparoscopic parastomal hernia repair is feasible and safe: early results of a prospective clinical study including 55 consecutive patients 显示文摘 | Hansson BME de Hingh IHJT Bleichrodt RP | 2007 | Surg Endosc2007，21，6： | 1 |
| 11 | Circulating matrix metalloproteinase-9 is transiently elevated atter colorectal surgery显示文摘 | de Hingh IH Waas ET Lomme RM | 2004 | Int J Colorectal Dis2004，19，5： | 1 |
| 12 | Quality of life of older rectal cancer patients is not impaired by a permanent stoma显示文摘 | R.G. Orsini M.S.Y. Thong L.V. van de Poll-Franse G.D. Slooter G.A.P. Nieuwenhuijzen H.J.T. Rutten I.H.J.T. de Hingh | 2012 | European Journal of Surgical Oncology2012，，： | 1 |
| 13 | 结直肠癌腹膜转移的治疗:新事实、新知识和新未来显示文摘结直肠癌腹膜转移(colorectal cancer peritoneal metastasis,CRCPM)一直是荷兰临床肿瘤学研究的重点领域之一,对比系统化疗加姑息手术治疗,CRCPM患者更易从肿瘤细胞减灭术(cytoreductive surgery,CRS)加腹腔热灌注化疗(hyperthermic intraperitoneal chemotherapy,HIPEC)中获益,CRS+HIPEC在治疗CRCPM中已具有稳定的临床基础。目前,荷兰建立了全国肿瘤登记处,对所有腹膜癌病例进行详细登记和分析。本文重点介绍了荷兰CRCPM最新研究,包括流行病学研究、多中心随机临床试验、基础和转化研究的新成果,给出了国际热点问题和学术争鸣的荷兰答案,提出了腹膜肿瘤学未来发展的新机遇和新方向。 | Ignace de Hingh 李兵(翻译) 李雁(审校) | 2022 | 中国肿瘤临床2022，49，24： | 1 |
| 14 | Circulating matrixmetallopro-teinase-9 is transiently elevated after coloreetal surgery 显示文摘 | de Hingh IH Waas ET Lomme RM | 2004 | Int J Color- ectal Dis2004，19，5： | 1 |
| 15 | Incidence and treatment of recurrent disease after cytoreductive surgery and intraperitoneal chemotherapy for peritoneally metastasized colorectal cancer: A systematic review显示文摘 | T.R. van Oudheusden S.W. Nienhuijs M.D. Luyer G.A. Nieuwenhuijzen V.E. Lemmens H.J. Rutten I.H. de Hingh | 2015 | European Journal of Surgical Oncology2015，，： | 1 |
| 16 | Impact of centralization of pancreatic cancer surgery on resection rates and survival显示文摘 | G. A. Gooiker V. E. P. P. Lemmens M. G. Besselink O. R. Busch B. A. Bonsing I. Q. Molenaar R. A. E. M. Tollenaar I. H. J. T. de Hingh M. W. J. M. Wouters | 2014 | Br J Surg2014，，8： | 1 |
| 17 | Bevacizumab in Addition to Palliative Chemotherapy for Patients With Peritoneal Carcinomatosis of Colorectal Origin: A Nationwide Population-Based Study显示文摘 | Lieke G.E.M. Razenberg Yvette R.B.M. van Geste Valery E.P.P. Lemmens Ignace H.J.T. de Hingh Geert-Jan Creemers | 2015 | Clinical Colorectal Cancer2015，，： | 1 |
| 18 | Angiogenesis-Related Markers and Prognosis After Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy for Metastatic Colorectal Cancer显示文摘 | de Cuba EM de Hingh IH Sluiter NR | 2016 | Ann Surg Oncol2016，23，5： | 1 |
| 19 | Laparoscopic parastomal hernia repair is feasible and safe: early results of a prospective clinical study including 55 consecutive patients显示文摘 | Hansson BM de Hingh IH Bleichrodt RP | 2007 | Surg Endosc2007，21，6： | 1 |
| 20 | A hospital survey of postpar-tum depression education atghe time of delivery 显示文摘 | Garg A Morton S Hingh A | 2005 | JOb-stetrie Gynecology Neonatal Knurs2005，34，5： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员