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| 1 | 由二种烟煤制备碳纳米管的探索性研究显示文摘以一种中国烟煤和一种新西兰烟煤为原料 ,采用电弧等离子体法制备碳纳米管。碳纳米管及其副产物富勒烯烟灰的表征采用扫描电镜 (SEM)和红外光谱 (FT IR)等技术。结果表明 :电弧放电时的缓冲气体压力对碳纳米管的产率影响很大 ;在一定的缓冲气压下电极间电流和电极间距各存在一最佳值。在He气压力为 0 .0 6 6 5MPa、工作电流为 40A条件下进行电弧放电 ,阴极上棒状沉积物的内芯中碳纳米管含量高达 75 %以上。基于实验结果 。 | 邱介山 韩红梅 周颖 胡德生 曾适之 P J F Harris | 2001 | 新型炭材料2001，16，4： | 30 |
| 2 | Modulation of tau phosphorylation by environmental copper显示文摘Background:The transition metal copper enhances amyloidβaggregation and neurotoxicity,and in models of concomitant amyloid and tau pathology,copper also promotes tau aggregation.Since it is not clear if the effects of environmental copper upon tau pathology are dependent on the presence of pathological amyloidβ,we tested the effects of copper overload and complexing in disease models which lack pathological amyloidβ.Methods:We used cell culture and transgenic murine models to test the effects of environmental copper on tau phosphorylation.We used oral zinc acetate as a copper lowering agent in mice and examined changes in blood and brain metals through inductively coupled plasma mass spectroscopy.Behavioral effects of copper lowering were assessed with Morris water maze and novel object recognition tasks.Changes in tau phosphorylation were examined by phosphorylation specific antibodies on Western blots.Results:In human neuroblastoma cells,excess copper promoted tau phosphorylation and a copper complexing agent,tetrathiomolybdate,attenuated tau phosphorylation.In a transgenic mouse model expressing wild type human tau,copper-lowering by oral zinc suppressed plasma and brain levels of copper,and resulted in a marked attenuation of tau phosphorylation.No significant changes in behavior were observed with copper lowering,but a trend to improved recognition of the novel object was observed in zinc acetate treated mice.Conclusions:We propose that reduction of brain copper by blocking uptake of copper from the diet may be a viable strategy for modulating tau pathology in Alzheimer’s disease.The potential benefits of this approach are tempered by the absence of a behavioral benefit and by the health risks of excessive lowering of copper. | Kellen Voss Christopher Harris Martina Ralle Megan Duffy Charles Murchison Joseph F Quinn | 2014 | Translational Neurodegeneration2014，3，1： | 3 |
| 3 | Resection of pancreatic cystic neoplasms in recurrent acute pancreatitis prevents recurrent pancreatitis but does not identify more malignancies显示文摘BACKGROUND Recurrent acute pancreatitis(RAP)may be a presenting feature of and an indication for resection of pancreatic cysts,including intra-ductal papillary mucinous neoplasm(IPMN).Few data are available regarding the prevalence of malignancy and post-operative RAP in this population.AIM To study the role of resection to help prevent RAP and analyze if presentation as RAP would be a predictor for malignancy.METHODS This retrospective study assessed 172 patients who underwent surgical resection of pancreatic cystic neoplasms at a university hospital between 2002 and 2016.The prevalence of preoperative high-risk cyst features,and of neoplasia was compared between patients with and without RAP.To identify the cause of pancreatitis,all the patients had a detailed history of alcohol,smoking,medications obtained,and had cross-sectional imaging(contrast-enhanced computed tomography/magnetic resonance imaging)and endoscopic ultrasound to look for gallstone etiology and other structural causes for pancreatitis.The incidence of RAP post-resection was the primary outcome.RESULTS IPMN accounted for 101 cases(58.7%){[branch duct(BD)59(34.3%),main duct(MD)42](24.4%)}.Twenty-nine(16.9%)presented with RAP(mean 2.2 episodes):15 had BD-IPMN,8 MD-IPMN,5 mucinous cystic neoplasm and 1 serous cystic neoplasm.Malignancy was similar among those with vs without RAP for all patients[6/29(20.7%)vs 24/143(16.8%)]and IPMN patients[6/23(26.1%)vs 23/78(29.5%)],although tended to be higher with RAP in BD-IPMN,[5/15(33.3%)vs 3/44(6.8%),P=0.04].At mean follow-up of 7.2 years,1(3.4%)RAP patient had post-resection RAP.The mean episodes of acute pancreatitis before vs after surgery were 3.4 vs 0.02(P<0.0001).CONCLUSION Malignancy was not increased in patients with pancreatic cystic neoplasms who have RAP compared to those without RAP.In addition,specific cyst characteristics were not clearly associated with RAP.The incidence of RAP was markedly decreased in almost all patients following cyst resection. | Thiruvengadam Muniraj Harry R Aslanian Loren Laine Priya A Jamidar James F Farrell Kisha A Mitchell Ronald R Salem | 2021 | World Journal of Gastroenterology2021，27，15： | 3 |
| 4 | Foreword显示文摘The contributions to this Special Issue were called on the occasion of the upcoming birthday anniversary of one of the outstanding scientists in field of mantle rheology and rock deformation, Prof. Zhenmin Jin, China University of Geosciences, to celebrate | Harry W Green II 章军锋 Larissa F Dobrzhinetskaya Tetsuo Irifune | 2010 | Journal of Earth Science2010，21，5： | 2 |
| 5 | Sarcopenia: An Undiagnosed Condition in Older Adults. Current Consensus Definition: Prevalence, Etiology, and Consequences. International Working Group on Sarcopenia显示文摘 | Roger A. Fielding Bruno Vellas William J. Evans Shalender Bhasin John E. Morley Anne B. Newman Gabor Abellan van Kan Sandrine Andrieu Juergen Bauer Denis Breuille Tommy Cederholm Julie Chandler Capucine De Meynard Lorenzo Donini Tamara Harris Aimo Kannt F | 2011 | Journal of the American Medical Directors Association2011，，4： | 2 |
| 6 | Fecal calprotectin concentration predicts outcome in inflammatory bowel disease after induction therapy with TNFα blocking agents显示文摘 | Pauliina Molander Clas‐G?ran af Bj?rkesten Harri Mustonen Johanna Haapam?ki Matti Vauhkonen Kaija‐Leena Kolho Martti F?rkkil? Taina Sipponen | 2012 | Inflamm Bowel Dis2012，，11： | 2 |
| 7 | A Simple Chemical Method of Opening nad Filling Carbon Nanotubes显示文摘 | Tsang S C Chen Y K Harris P J F | 1994 | Nature1994，372，1： | 1 |
| 8 | Computational fluid dynamics for chemical reactor engineering显示文摘 | Harris C K Roekaerts D Rosendal F J J | 1996 | Chem Eng Sci1996，51，10： | 1 |
| 9 | Performance assessment of multivariable feedback controllers显示文摘 | Harris T J Boudrean F MacGregor J F | 1996 | Automatica1996，32，11： | 1 |
| 10 | Work - life Benefits and Positive Organizational Behavior:Is There A Connection 显示文摘 | Muse L Harris S G Giles W F Feild H S | 2008 | Journal of Or- ganizational Behavior2008，29，2： | 1 |
| 11 | The Effect of Financial Liberalization on the Capital Structure and Invest- ment Decisions of Indonesian Manufacturing Establishments 显示文摘 | Harris J R Schiantarelli F Siregar M G | 1994 | World Bank Economic Review1994，8，1： | 1 |
| 12 | Thining and opening of carbon nanotubes by oxidation using carbon dioxide 显示文摘 | Tsang S C Harris P J F Green M L H | 1993 | Nature1993，362，： | 1 |
| 13 | Tracking fish by airborne radar - fishermen could be the winner显示文摘 | GRIFFITHS F B LYNE V D HARRIS G P et el | 1989 | Australian Fisheries1989，48，： | 1 |
| 14 | A simple chemical mehod of opening and filling carbon nanotubes显示文摘 | TSANG S C CHEN Y K HARRIS P J F | 1994 | Nature1994，372，： | 1 |
| 15 | Quality and chemistry of throughfall as influenced by forest type and season显示文摘 | Henderson G S Harris C F Todd D E | 1977 | Journal of Ecology1977，65，2： | 1 |
| 16 | Deciphering the biology of My cobacterium tuberculosis from the complete genome sequence 显示文摘 | Cole S T Brosch R Parkhill J Gamier T Churcher C Harris D Gordon S V Eiglmeier K Gas S Barry C E Tekaia F Badcock K Basham D Brown D Chillingworth T Cormor R Davies R Devlin K FeltweU T Gentles S Hamlin N Holroyd S Hornsby T Jagels K Kroghs A McLean J Moule S Murphy L Oliver K Osborne J Quail M A Rafandream M A Rogers J Rutter S Seeger K Skelton J Squaraes R Squares S Sulston J E Taylo K Whitehead S Barrell B G | 1998 | Nature1998，393，： | 1 |
| 17 | A prospective study of computer- aided design and manufacture of titanium plate for cranioplasty and its clinical outcome 显示文摘 | Joffe J Harris M Kahugu F | 1999 | Br J Neurosurg1999，13，6： | 1 |
| 18 | Shh-Bmp2 signaling module and the evolutionary origin and diversification of feathers 显示文摘 | Harris M P Fallon J F Prum R O | 2002 | J Exp Zool2002，，294： | 1 |
| 19 | Color Doppler ultrasound imaging of the eye and orbit显示文摘 | Williamson TH Frcophth F Harris A | | 0，，： | 1 |
| 20 | Role of calpains in diabetes mellitus- induced cataractogenesis: a mini review 显示文摘 | Biswas S Harris F Sing_h J | 2004 | MolCell Biochem2004，261，12： | 1 |
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