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| 1 | Landscape changes have greater effects than climate changes on six insect pests in China显示文摘In recent years, global changes are the major causes of frequent, widespread outbreaks of pests in mosaic landscapes, which have received substantial attention worldwide. We collected data on global changes(landscape and climate) and economic damage caused by six main insect pests during 1951–2010 in China. Landscape changes had significant effects on all six insect pests. Pest damage increased significantly with increasing arable land area in agricultural landscapes. However, climate changes had no effect on damage caused by pests, except for the rice leaf roller(Cnaphalocrocis medinalis Guenee) and armyworm(Mythimna separate(Walker)), which caused less damage to crops with increasing mean temperature. Our results indicate that there is slight evidence of possible offset effects of climate changes on the increasing damage from these two agricultural pests. Landscape changes have caused serious outbreaks of several species, which suggests the possibility of the use of landscape design for the control of pest populations through habitat rearrangement. Landscape manipulation may be used as a green method to achieve sustainable pest management with minimal use of insecticides and herbicides. | Zihua Zhao Hardev S Sandhu Fang Ouyang Feng Ge | 2016 | Science China(Life Sciences)2016，59，6： | 5 |
| 2 | Expression of Engrailed-2 (EN2) protein in bladder cancer and its potential utility as a urinary diagnostic biomarker显示文摘 | Richard Morgan Richard T. Bryan Saqib Javed Francesca Launchbury Maurice P. Zeegers K.K. Cheng Nicholas D. James D. Michael A. Wallace Carolyn D. Hurst Douglas G. Ward Margaret A. Knowles Hardev Pandha | 2013 | European Journal of Cancer2013，，9： | 1 |
| 3 | Urinary engrailed‐2 (EN2) levels predict tumour volume in men undergoing radical prostatectomy for prostate cancer显示文摘 | Hardev Pandha Karen D. Sorensen Thorsten F. Orntoft Stephen Langley Soren Hoyer Michael Borre Richard Morgan | 2012 | BJU International2012，，6： | 1 |
| 4 | dendritic cell immunotherapy for urological cancers using cryopreserved allogenein tumor lysate-pulsed cell显示文摘 | Pandha Hardev S Menard S | 2004 | BJU International2004，594，3： | 1 |
| 5 | The abrogation of the HOXB7/PBX2 complex induces apoptosis in melanoma through the miR‐221&222‐c‐FOS pathway显示文摘 | M. Cristina Errico Federica Felicetti Lisabianca Bottero Gianfranco Mattia Alessandra Boe Nadia Felli Marina Petrini Maria Bellenghi Hardev S. Pandha Marco Calvaruso Claudio Tripodo Mario P. Colombo Richard Morgan Alessandra Carè | 2013 | Int J Cancer2013，，4： | 1 |
| 6 | New developments in triple-offset butterfly valves显示文摘 | HARDEV S P | 2004 | World Pumps2004，，9： | 1 |
| 7 | Capturing the interaction types of two Bt toxins CrylAc and Cry2Ab on suppressing the cotton bollworm by using multi-exponential equations显示文摘 | Pei-Jian Shi Ji-Zhen Wei Hardev S. Sandhu Ge-Mei Liang | 2016 | Insect Science2016，23，4： | 1 |
| 8 | dendritic cell immunotherapy for urological cancers using cryopreserved allogenein tumor lysate-pulsed cell显示文摘 | Pandha Hardev S Menard S | 2004 | BJU International2004，94，3： | 1 |
| 9 | The abrogation of the HOXB7/PBX2 complex induces apoptosis in melanoma through the miR‐221&222‐c‐FOS pathway显示文摘 | M. Cristina Errico Federica Felicetti Lisabianca Bottero Gianfranco Mattia Alessandra Boe Nadia Felli Marina Petrini Maria Bellenghi Hardev S. Pandha Marco Calvaruso Claudio Tripodo Mario P. Colombo Richard Morgan Alessandra Carè | 2013 | Int. J. Cancer2013，，4： | 1 |
| 10 | A high-efficiency wide-color-camut solid-state backlight system for LCDs using quantum dot enhancement film显示文摘 | CHEN J HARDEV V HARTLOVE J | 2012 | SID Symposium Digest of Technical Papers2012，43，1： | 1 |
| 11 | Heated tumour cells of autologous and allogeneic origin elicit anti-tumour immunity显示文摘 | Stephen M. Todryk Jonathan Eaton Lindsay Birchall Rebecca Greenhalgh Diane Soars Angus G. Dalgleish Alan A. Melcher Hardev S. Pandha | 2004 | Cancer Immunology Immunotherapy2004，，4： | 1 |
| 12 | Immunoregulatory effects of freeze injured whole tumour cells on human dendritic cells using an in vitro cryotherapy model显示文摘 | Mohamed Ismail Richard Morgan Kevin Harrington John Davies Hardev Pandha | 2010 | Cryobiology2010，，3： | 1 |
| 13 | Individualized therapy for metastatic renal cell carcinoma显示文摘Metastatic Renal Cell Carcinoma(mRCC)is a highly heterogeneous disease that is notoriously difficult to treat successfully.However,the discovery of novel,targeted therapies over the last decade has revolutionized its management.As the therapeutic options continue to evolve,developing a more individualized treatment strategy is of paramount importance.The International mRCC Database Consortium(IMDC)is a prognostic model that is commonly used in trials and clinical settings to risk stratify patients.This allows for optimal therapy selection on a more individual basis.However,the distinct lack of validated predictive biomarkers in mRCC renders it difficult to assess therapy response.An improved understanding of tumor biology and genetics has prompted a shift from cytokine therapy to the use of vascular endothelial growth factor(VEGF)inhibitors,tyrosine kinase Inhibitors,immune checkpoint inhibitors or combination strategies.Studies have identified some putative markers and genetic mutations as potential predictors of therapy response.Early results are promising,and there are many ongoing trials further assessing their suitability for clinical use.This review will evaluate the current treatment landscape and molecular biology of mRCC,with a specific focus on the prognostic and predictive markers available to guide treatment options and further improve patient outcomes. | Bambang T.Atmaja Izabelle Wood Suyanto Suyanto Paramvir Sawhney Agnieszka Michael Hardev Pandha | 2021 | Journal of Cancer Metastasis and Treatment2021，7，1： | 0 |
| 14 | Adjuvant therapy for renal cell carcinoma显示文摘Recent advances in the treatment of metastatic renal cell carcinoma expose a gap in the treatment of less advanced,localized disease.Tyrosine kinase inhibitors,which revolutionized the treatment of metastatic disease,have not provided a similar survival benefit in the adjuvant setting and currently only sunitinib is approved by the Food and Drug Administration for adjuvant treatment in patients with high-risk of recurrence based on S-TRAC disease-free survival data.The advent of immune checkpoint inhibitors has offered a fresh hope in the field of adjuvant treatment after encouraging results are seen with combination of immune checkpoint inhibitors as well as with targeted therapy in the metastatic setting.Several studies are investigating these combinations in the adjuvant setting,and it is hoped that they will bring about a better outcome for a largely unmet need in kidney cancer treatment. | Paramvir Sawhney Suyanto Suyanto Agnieszka Michael Hardev Pandha | 2021 | Journal of Cancer Metastasis and Treatment2021，7，1： | 0 |
| 15 | Comparison of seed morphology of two ginkgo cultivars显示文摘Ginkgo biloba L. is a precious relic tree species with important economic value. Seeds, as a vital reproductive organ of plants, can be used to distinguish cultivars of the species. We chose 400 seeds from two cultivars of ginkgo(“Fozhi” and “Maling”;200 seeds for each cultivar) as the study material and used the Gielis equation to fit the projected shape of these seeds. The coefficients of variation(CV) in root mean squared errors(RMSE)obtained from the fitted data were used to compare the level of inter-cultivar variations in seed shape. We also used the covariance analysis to compare the allometric relationships between seed weights and projected areas of these two cultivars. The Gielis equation fitted well the seedshapes of two ginkgo cultivars. The lower CV in RMSE of cultivar “Fozhi” than “Maling” indicated a less symmetrical seed shape in the latter than the former. The bootstrap percentile method showed that the seed shape differences between the two cultivars were significant. However, there was no significant difference in the exponents between the seed weights and the projected areas of these two cultivars.Overall, the significant differences in shapes between the seeds of two ginkgo cultivars were well explained by the Gielis equation;this model can be further extended to compare morphological differences in other ginkgo cultivars, and even for plant seeds or animal eggs that have similar oval shapes. | Fang Tian Yujun Wang Hardev S.Sandhu Johan Gielis Peijian Shi | 2020 | Journal of Forestry Research2020，31，3： | 0 |
| 16 | HOX transcription factors and the prostate tumor microenvironment显示文摘It is now well established that the tumor microenvironment plays an essential role in the survival,growth,invasion,and spread of cancer through the regulation of angiogenesis and localized immune responses.This review examines the role of the HOX genes,which encode a family of homeodomain-containing transcription factors,in the interaction between prostate tumors and their microenvironment.Previous studies have established that HOX genes have an important function in prostate cancer cell survival in vitro and in vivo,but there is also evidence that HOX proteins regulate the expression of genes in the cancer cell that influence the tumor microenvironment,and that cells in the microenvironment likewise express HOX genes that confer a tumor-supportive function.Here we provide an overview of these studies that,taken together,indicate that the HOX genes help mediate cross talk between prostate tumors and their microenvironment. | Richard Morgan Hardev S.Pandha | 2017 | Journal of Cancer Metastasis and Treatment2017，3，1： | 0 |
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