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| 1 | 胆固醇酯转移蛋白基因的蛋白质截断型变异体与冠状动脉性心脏病风险的关系显示文摘随机对照试验结果表明,抑制胆固醇酯转运蛋白(cholesteryl ester transfer protein,CETP)的疗法并不能降低冠状动脉性心脏病(coronary heart disease,CHD)的发生风险。研究失败的可能原因包括靶目标无效、靶目标外小分子的不良反应和随机对照设计因素影响等。在编码药物靶点的基因中具有天然存在的遗传变异,以此为基础,人类研究可以深入了解针对基因产物的治疗的潜在功效和安全性。 | Nomura A Won HH Khera AV Takeuchi F Ito K McCarthy S Emdin CA Klarin D Natarajan P Zekavat SM Gupta N Peloso GM Borecki IB Teslovich TM Asselta R Duga S Merlini PA Correa A Kessler T Wilson JG Bown MJ Hall AS Braund PS Carey DJ Murray MF Kirchner HL Leader JB Lavage DR Manus JN Hartze DN Samani NJ Schunkert H Marrugat J Elosua R McPherson R Farrall M Watkins H Juang JJ Hsiung CA Lin SY Wang JS Tada H Kawashiri MA Inazu A Yamagishi M Katsuya T Nakashima E Nakatochi M Yamamoto K Yokota M Momozawa Y Rotter JI Lander ES Rader DJ Danesh J Ardissino D Gabriel S Willer CJ Abecasis GR Saleheen D Kubo M Kato N Ida Chen YD Dewey FE Kathiresan S 刘莉 叶鹏 | 2017 | 中华高血压杂志2017，25，9： | 2 |
| 2 | Synthesis,physicochemical properties, and biological evaluation of N-substituted-2-alkyl-3-hydroxy-4 ( 1H )-pyridi-nones:orally active iron chelators with clinical potential显示文摘 | Dobbin PS Hider RC Hall AD | 1993 | J Med Chem1993，36，17： | 1 |
| 3 | Economic evaluation of genomic test-directed chemotherapy for early-stage lymph node- positive breast cancer显示文摘 | Hall PS McCabe C Stein RC | 2012 | J Natl Cancer Inst2012，104，1： | 1 |
| 4 | Economic Evaluation of Genomic Test-Directed Chemotherapy for Early-Stage Lymph Node-Positive Breast Cancer显示文摘 | Hall PS McCabe C Stein RC | 2012 | J Nad Cancer Inst2012，104，1： | 1 |
| 5 | Primary pulmonary hyperten- sion:prolonged cardiac arrest and successful resuscitation following induction of anesthesia for heart lung transplantation 显示文摘 | Myles PS Hall JL Berry CB | 1994 | J Cardio- thorae Vase Anesth1994，8，： | 1 |
| 6 | Retinal ischemia leads to apoptosis which is ameliorated by aurintricarboxylic acid显示文摘 | Rosenbaum DM Rosenbaum PS Gupta A Michaelson MD Hall DH Kessler JA | 1997 | Vision Res1997，37，24： | 1 |
| 7 | Flow cytometric investigation of peri-anaesthetie anaphylaxis using CD63 and CD203c 显示文摘 | Sudheer PS Hall JE Read GF | 2005 | Anaes- thesia2005，60，3： | 1 |
| 8 | Inhibition of esophageal carcinogenesis in corn-fed rats by riboflavin, nicotinic acid, selenium, molybdenum, zinc, and magnesium 显示文摘 | Van Rensburg SJ Hall JM Gathercole PS | 1986 | Nutr Cancer1986，8，1： | 1 |
| 9 | The inflammatory bowel disease (IBD) suscepti- bility genes NOD1 and NOD2 have conserved anti-bacterial roles in zebrafish 显示文摘 | Oehlers SH Flores MV Hall CI Swift S Crosier KE Crosier PS | 2011 | Dis Models Mech2011，4，6： | 1 |
| 10 | The role of the p53 protein in the selective vulnerability of the inner retina to transient ischemia显示文摘 | Rosenbaum DM Rosenbaum PS Gupta H Singh M Aggeurwal A Hall DH | 1998 | Invest Ophthalmol Vis Sci1998，39，11： | 1 |
| 11 | Genomic sequence of the pathogenic and allergenic filamentous fungus Aspergillus fumigatus 显示文摘 | Nierman WC Pain A Anderson MJ Wortman JR Kim HS Arroyo J Berriman M Abe K Archer DB Bermejo C Bennett J Bowyer P Chen D Collins M Coulsen R Davies R Dyer PS Farman M Fedorova N Fedorova N Feldblyum TV Fischer R Fosker N Fraser A Garcla JL Garcia MJ Goble A Goldman GH Gomi K Griffith- Jones S Gwilliam R Haas B Haas H Harris D Horiuchi H Huang J Humphray S Jim6nez J Keller N Khouri H Kitamoto K Kobayashi T Konzack S Kulkarni R Kumagai T Lafon A Latgo JP Li W Lord A Lu C Majoros WH May GS Miller BL Mohamoud Y Molina M Monod M Mouyna I Mulligan S Murphy L O'Neil S Paulsen I Pefialva MA Pertea M Price C Pritchard BL Quail MA Rabbinowitsch E Rawlins N Rajandream MA Reichard U Renauld H Robson GD Rodriguez de Cordoba S Rodriguez-Pefia JM Ronning CM Putter S Salzberg SL Sanchez M Sfnchez-Ferrero JC Saunders D Seeger K Squares R Squares S Takeuchi M Tekaia F Turner G Vazquez de Aldana CR Weidman J White O Woodward J Yu JH Fraser C Galagan JE Asai K Machida M Hall N Barrell B Denning DW | 2005 | Nature2005，438，7071： | 1 |
| 12 | Inhibition of esophageal cancinogenesis in corn-fed rats by riboflavin, nicotinic acid,selenium,molybdenum,zinc and magnesium显示文摘 | Van RSJ Hall JM Gathercole PS | 1986 | Nutr Cancer1986，8，： | 1 |
| 13 | Quiescent leukemic cells account for minimal residual disease in children lymphoblastic leukemia显示文摘 | Lutz C Woll PS Hall G | 2013 | Leukemia2013，27，5： | 1 |
| 14 | Expanding knowledge in family health care显示文摘 | Tomlinson PS Hall EO | 2003 | Seand J Caring Sci2003，17，： | 1 |
| 15 | Cocaine, reward, movement and monoaminetransporters显示文摘 | Uhl GR Hall PS Sora | 2002 | Mol Psychiatry2002，7，： | 1 |
| 16 | Treatment of chronic rhinosi-nusitis exacerbations due to methicillin - resistant Staphylococcus aureus with mupirocin irrigations 显示文摘 | Solares CA Batra PS Hall GS | 2006 | Am J Otolaryngol - Head Neck Med Surge2006，27，： | 1 |
| 17 | CPW-FED switchable top disk-loaded monopole array antenna显示文摘 | Kamarudin MR Hall PS Colombel F Himd M | 2009 | Journal of Electromagnetic Waves and Applications2009，23，1112： | 1 |
| 18 | 一种收发同时工作的集成有源阵天线显示文摘一种收发同时工作的集成有源阵天线沙济彰P.S.HalM.J.Cryan(河海大学常州分校,常州213022)(UniversityofBirmingham,Birmingham,B152TT,U.K.)有源天线是指把有源器件集成到天线之中,或将两者... | 沙济彰 Hall,PS | 1997 | 东南大学学报(自然科学版)1997，27，4： | 0 |
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