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| 1 | 脑保护的药理学显示文摘巴比妥类药巴比妥类药对CNS保护的主要机理是能降低脑代谢率,从而改善氧供/需比值;确切地说这类药物能选择性地降低突触传导耗能同时维持细胞基本功能所需能;它们使CBF向缺血组织再分布且降低颅内压(ICP),也对改善代谢起辅助作用。局灶性缺血巴比妥类药物对局灶性缺血有特殊的保护作用。局灶性缺血时尽管氧供减少,突触活动仍然存在。 | Hall R Murdock J 张文 俊节 | 1992 | 国外医学(麻醉学与复苏分册)1992，13，2： | 4 |
| 2 | 7-iodo-8-hydroxy quinoline-5-sulfonic acid as a reagent for the colorimetric determination of ferric iron显示文摘 | Yoe J H Hall R T | 1937 | J Am Chem SOC1937，54，： | 2 |
| 3 | Age at diagnosis of type 2 diabetes and cardiovascular risk factor profile:A pooled analysis显示文摘BACKGROUND The diagnosis of type 2 diabetes(T2D)in younger adults,an increasingly common public health issue,is associated with a higher risk of cardiovascular complications and mortality,which may be due to a more adverse cardiovascular risk profile in individuals diagnosed at a younger age.AIM To investigate the association between age at diagnosis and the cardiovascular risk profile in adults with T2D.METHODS A pooled dataset was used,comprised of data from five previous studies of adults with T2D,including 1409 participants of whom 196 were diagnosed with T2D under the age of 40 years.Anthropometric and blood biomarker measurements included body weight,body mass index(BMI),waist circumference,body fat percentage,glycaemic control(HbA1c),lipid profile and blood pressure.Univariable and multivariable linear regression models,adjusted for diabetes duration,sex,ethnicity and smoking status,were used to investigate the association between age at diagnosis and each cardiovascular risk factor.RESULTS A higher proportion of participants diagnosed with T2D under the age of 40 were female,current smokers and treated with glucose-lowering medications,compared to participants diagnosed later in life.Participants diagnosed with T2D under the age of 40 also had higher body weight,BMI,waist circumference and body fat percentage,in addition to a more adverse lipid profile,compared to participants diagnosed at an older age.Modelling results showed that each one year reduction in age at diagnosis was significantly associated with 0.67 kg higher body weight[95%confidence interval(CI):0.52-0.82 kg],0.18 kg/m^(2) higher BMI(95%CI:0.10-0.25)and 0.32 cm higher waist circumference(95%CI:0.14-0.49),after adjustment for duration of diabetes and other confounders.Younger age at diagnosis was also significantly associated with higher HbA1c,total cholesterol,low-density lipoprotein cholesterol and triglycerides.CONCLUSION The diagnosis of T2D earlier in life is associated with a worse cardiovascular risk factor profile,compared to those diagnosed later in life. | Mary M Barker Francesco Zaccardi Emer M Brady Gaurav S Gulsin Andrew P Hall Joseph Henson Zin ZinHtike Kamlesh Khunti Gerald P McCann Emma L Redman David R Webb Emma G Wilmot Tom Yates Jian Yeo Melanie J Davies Jack A Sargeant | 2022 | World Journal of Diabetes2022，13，3： | 2 |
| 4 | Measles and atopy in Guinea-Bissau显示文摘 | Shaheen S O Aaby P Hall A J | 1996 | Lancet1996，347，9018： | 2 |
| 5 | HA receptors: regulators of signaling to the cytoskeleton显示文摘 | Entwistle J Hall C L Turley E A | 1996 | J Cell Biochem1996，61，4： | 2 |
| 6 | Aflatoxin Exposure and Viral Hepatitis in the Etiology of Liver Cirrhosis in The Gambia, West Africa显示文摘 | Kuniholm Mark H Lesi Olufunmilayo A Mendy Maimuna Akano Aliu O Sam Omar Hall Andrew J Whittle Hilton Bah Ebrima Goedert James J Hainaut Pierre Kirk Gregory D | 2008 | Environmental Health Perspectives2008，，11： | 2 |
| 7 | 胆固醇酯转移蛋白基因的蛋白质截断型变异体与冠状动脉性心脏病风险的关系显示文摘随机对照试验结果表明,抑制胆固醇酯转运蛋白(cholesteryl ester transfer protein,CETP)的疗法并不能降低冠状动脉性心脏病(coronary heart disease,CHD)的发生风险。研究失败的可能原因包括靶目标无效、靶目标外小分子的不良反应和随机对照设计因素影响等。在编码药物靶点的基因中具有天然存在的遗传变异,以此为基础,人类研究可以深入了解针对基因产物的治疗的潜在功效和安全性。 | Nomura A Won HH Khera AV Takeuchi F Ito K McCarthy S Emdin CA Klarin D Natarajan P Zekavat SM Gupta N Peloso GM Borecki IB Teslovich TM Asselta R Duga S Merlini PA Correa A Kessler T Wilson JG Bown MJ Hall AS Braund PS Carey DJ Murray MF Kirchner HL Leader JB Lavage DR Manus JN Hartze DN Samani NJ Schunkert H Marrugat J Elosua R McPherson R Farrall M Watkins H Juang JJ Hsiung CA Lin SY Wang JS Tada H Kawashiri MA Inazu A Yamagishi M Katsuya T Nakashima E Nakatochi M Yamamoto K Yokota M Momozawa Y Rotter JI Lander ES Rader DJ Danesh J Ardissino D Gabriel S Willer CJ Abecasis GR Saleheen D Kubo M Kato N Ida Chen YD Dewey FE Kathiresan S 刘莉 叶鹏 | 2017 | 中华高血压杂志2017，25，9： | 2 |
| 8 | Complete mappings of finite groups 显示文摘 | Hall M Paige L J | 1957 | Pacific Journal of Mathematics1957，5，： | 2 |
| 9 | Sevoflurane(12% and 8%)inhalational induction in children显示文摘 | Chawathe M Zatman T Hall J E | 2005 | Paediatr Anaesth2005，15，6： | 1 |
| 10 | Pond heat and temperature regulation (PHATR) : Modeling temperature and energy balances in earthen outdoor aquaculture ponds显示文摘 | Lamoureux J Tiersch T R Hall S G | 2006 | Aquaculural Engineering2006，34，2： | 1 |
| 11 | Three dimensional transonic aeroelasticity using proper orthogonal decompo- sition-based reduced order models显示文摘 | Thomas J P Dowell E H Hall K C | 2003 | Journal of Aircraft2003，40，3： | 1 |
| 12 | Carburization behavior of HK40 steel in furnaces used for ethylene production 显示文摘 | D J Hall M K Hossain and R F Atkinson | 1982 | High Temperature High Pressure1982，14，： | 1 |
| 13 | Objective methods for registration landmarks and determining cloud motions from satellite data显示文摘 | Endlich R M Wolf D E and Brain A E | 1972 | IEEE Trans1972，21，： | 1 |
| 14 | Interaction of amylin with calcitonin gene-related peptide receptors in the microvasculature of the hamster cheek pouch in vivo显示文摘 | Brain S D | 1999 | Br J Pharmacol1999，26，1： | 1 |
| 15 | Econometric mode1s for count data with an application to the patents-R&D relationship显示文摘 | Hausman J A Hall B H Griliches Z | 1984 | Econometrica1984，52，4： | 1 |
| 16 | Diagnostic assay recommended by the World Health Organization for swine origin influenza A (H1N1) virus cross-reacts with H5N1 influenza virus显示文摘 | Peacey M Hall R J Bocacao J | 2009 | J Clin Microbiol2009，47，： | 1 |
| 17 | The determination of the D/H ratio of non-exchangeable hydrogen in cellulose extracted from aquatic and land plants显示文摘 | Epstein S Yapp C J Hall J H | 1976 | Earth and Planetary Science Let- ters1976，30，2： | 1 |
| 18 | Diffusion imaging for evaluation of tumor therapies in preclinical animal models显示文摘 | Moffat BA Hall DE Stojanovska J | 2004 | MAGMA2004，17，3： | 1 |
| 19 | Complete mappings of finite groups显示文摘 | HALL M PAIGE L J | 1957 | Pacific Journal of Mathematics1957，5，： | 1 |
| 20 | Fatigue crack growth from foreign object damage under combined low and high cycle loading Part I : experimental studies 显示文摘 | Ding J Hall R F Bytne J | 2007 | International Journal of Fatigue2007，29，7： | 1 |
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