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| 1 | Advances in fabrication of ceramic corundum abrasives based on sol–gel process显示文摘Corundum abrasives with good chemical stability can be fabricated into various free abrasives and bonded abrasive tools that are widely used in the precision machining of various parts.However,these abrasives cannot satisfy the machining requirements of difficult-to-machine materials with high hardness,high strength,and strong wearing resistance.Although superhard abrasives can machine the above-mentioned materials,their dressing and manufacturing costs are high.By contrast,ceramic corundum abrasives fabricated by sol–gel method is a costeffective product between conventional and superhard abrasives.Ceramic corundum abrasives exhibit self-sharpening and high toughness.In this review,the optimization methods of ceramic corundum abrasive properties are introduced from three aspects:precursor synthesis,particle shaping,and sintering.Firstly,the functional mechanism of seeds and additives on the microstructural and mechanical properties of abrasives is analyzed.Specifically,seeds can reduce the phase transition temperature and improve fracture toughness.The grain size and uniformly dense structure can be controlled by applying an appropriate amount of multicomponent additives.Then,the urgent need of engineering application and machinability of special shape ceramic corundum abrasives is reviewed,and three methods of abrasive shaping are summarized.The micromold replication technique is highly advanced and can be used to prepare functional abrasives.Additionally,the influence of a new sintering method,namely,two-step sintering technique,on the microstructural and mechanical performance of ceramic corundum abrasives is summarized.Finally,the challenge and developmental trend of the optimization of ceramic corundum abrasives are prospected. | Baoteng HUANG Changhe LI Yanbin ZHANG Wenfeng DING Min YANG Yuying YANG Han ZHAI Xuefeng XU Dazhong WANG Sujan DEBNATH Muhammad JAMIL Hao Nan Li Hafiz Muhammad ALI Munish Kumar GUPTA Zafar SAID | 2021 | Chinese Journal of Aeronautics2021,34,6: | 11 |
| 2 | A review on promising phytochemical, nutritional and glycemic control studies on Moringa oleifera Lam. in tropical and sub-tropical regions显示文摘Plants have provided sources to find novel compounds. These plants are being used as therapeutic purposes since the birth of mankind. The traditional healers normally utilize medicinal plants as crude drugs while scientists using the folk claim as guides to explore medicinal plants. Moringa oleifera is a famous edible plant having therapeutic and nutritive values. The present study was designed to cumulate the research data regarding to what extent, phytochemical, nutritional and glycemic control studies has been explored using its different extracts. The articles indicated that the powder, aqueous, methanol and ethanol extracts of Moringa oleifera(leaves, pods, seeds, stem and root bark) have significant therapeutic herbal potential to treat diabetes mellitus. Collectively, the mechanism behind is intestinal glucose inhibition, insulin release as well as decrease in insulin resistance probably regeneration of b-cells of pancreas, increase in glutathione and reduction in malondialdehyde. Conclusively, this article give descriptive information about antidiabetic effect, claimed marker compounds and proposed antihyperglycemic mechanism of a single plant. It can be suggested a potential herbal source to treat diabetes mellitus as being widely accepted by major population as nutrition and therapeutic agent. | Hafiz Irfan Muhammad Mohd Zaini Asmawi Nurzalina Abdul Karim Khan | 2016 | Asian Pacific Journal of Tropical Biomedicine2016,6,10: | 8 |
| 3 | Milling Force Model for Aviation Aluminum Alloy: Academic Insight and Perspective Analysis显示文摘Aluminum alloy is the main structural material of aircraft,launch vehicle,spaceship,and space station and is processed by milling.However,tool wear and vibration are the bottlenecks in the milling process of aviation aluminum alloy.The machining accuracy and surface quality of aluminum alloy milling depend on the cutting parameters,material mechanical properties,machine tools,and other parameters.In particular,milling force is the crucial factor to determine material removal and workpiece surface integrity.However,establishing the prediction model of milling force is important and difficult because milling force is the result of multiparameter coupling of process system.The research progress of cutting force model is reviewed from three modeling methods:empirical model,finite element simulation,and instantaneous milling force model.The problems of cutting force modeling are also determined.In view of these problems,the future work direction is proposed in the following four aspects:(1)high-speed milling is adopted for the thin-walled structure of large aviation with large cutting depth,which easily produces high residual stress.The residual stress should be analyzed under this particular condition.(2)Multiple factors(e.g.,eccentric swing milling parameters,lubrication conditions,tools,tool and workpiece deformation,and size effect)should be considered comprehensively when modeling instantaneous milling forces,especially for micro milling and complex surface machining.(3)The database of milling force model,including the corresponding workpiece materials,working condition,cutting tools(geometric figures and coatings),and other parameters,should be established.(4)The effect of chatter on the prediction accuracy of milling force cannot be ignored in thin-walled workpiece milling.(5)The cutting force of aviation aluminum alloy milling under the condition of minimum quantity lubrication(mql)and nanofluid mql should be predicted. | Zhenjing Duan Changhe Li Wenfeng Ding Yanbin Zhang Min Yang Teng Gao Huajun Cao Xuefeng Xu Dazhong Wang Cong Mao Hao Nan Li Gupta Munish Kumar Zafar Said Sujan Debnath Muhammad Jamil Hafiz Muhammad Ali | 2021 | Chinese Journal of Mechanical Engineering2021,34,1: | 7 |
| 4 | Nano-enhanced biolubricant in sustainable manufacturing:From processability to mechanisms显示文摘To eliminate the negative effect of traditional metal-working fluids and achieve sustainable manufacturing,the usage of nano-enhanced biolubricant(NEBL)is widely researched in minimum quantify lubrication(MQL)machining.It's improved tool wear and surface integrity have been preliminarily verified by experimental studies.The previous review papers also concluded the major influencing factors of processability including nano-enhancer and lubricant types,NEBL concentration,micro droplet size,and so on.Nevertheless,the complex action of NEBL,from preparation,atomization,infiltration to heat transfer and anti-friction,is indistinct which limits preparation of process specifications and popularity in factories.Especially in the complex machining process,in-depth understanding is difficult and meaningful.To fll this gap,this paper concentrates on the comprehensive quantitative assessment of processability based on tribological,thermal,and machined surface quality aspects for NEBL application in turning,milling,and grinding.Then it attempts to answer mechanisms systematically considering multi-factor influence of molecular structure,physicochemical properties,concentration,and dispersion.Firstly,this paper reveals advanced lubrication and heat transfer mechanisms of NEBL by quantitative comparison with biolubricant-based MQL machining.Secondly,the distinctive filmformation,atomization,and infiltration mechanisms of NEBL,as distinguished from metal-working fluid,are clarified combining with its unique molecular structure and physical properties.Furtherly,the process optimization strategy is concluded based on the synergistic relationship analysis among process variables,physicochemical properties,machining mechanisms,and performance of NEBL.Finally,the future development directions are put forward aiming at current performance limitations of NEBL,which requires improvement on preparation and jet methods respects.This paper will help scientists deeply understand effective mechanism,formulate process specifications,and find future development trend of this technology. | Yanbin ZHANG Hao Nan LI Changhe LI Chuanzhen HUANG Hafiz Muhammad ALI Xuefeng XU Cong MAO Wenfeng DING Xin CUI Min YANG Tianbiao YU Muhammad JAMIL Munish Kumar GUPTA Dongzhou JIA Zafar SAID | 2022 | Friction2022,10,6: | 5 |
| 5 | Electrostatic atomization minimum quantity lubrication machining:from mechanism to application显示文摘Metal cutting fluids(MCFs)under flood conditions do not meet the urgent needs of reducing carbon emission.Biolubricant-based minimum quantity lubrication(MQL)is an effective alternative to flood lubrication.However,pneumatic atomization MQL has poor atomization properties,which is detrimental to occupational health.Therefore,electrostatic atomization MQL requires preliminary exploratory studies.However,systematic reviews are lacking in terms of capturing the current research status and development direction of this technology.This study aims to provide a comprehensive review and critical assessment of the existing understanding of electrostatic atomization MQL.This research can be used by scientists to gain insights into the action mechanism,theoretical basis,machining performance,and development direction of this technology.First,the critical equipment,eco-friendly atomization media(biolubricants),and empowering mechanisms of electrostatic atomization MQL are presented.Second,the advanced lubrication and heat transfer mechanisms of biolubricants are revealed by quantitatively comparing MQL with MCF-based wet machining.Third,the distinctive wetting and infiltration mechanisms of electrostatic atomization MQL,combined with its unique empowering mechanism and atomization method,are compared with those of pneumatic atomization MQL.Previous experiments have shown that electrostatic atomization MQL can reduce tool wear by 42.4%in metal cutting and improve the machined surface Ra by 47%compared with pneumatic atomization MQL.Finally,future development directions,including the improvement of the coordination parameters and equipment integration aspects,are proposed. | Wenhao Xu Changhe Li Yanbin Zhang Hafiz Muhammad Ali Shubham Sharma Runze Li Min Yang Teng Gao Mingzheng Liu Xiaoming Wang Zafar Said Xin Liu Zongming Zhou | 2022 | International Journal of Extreme Manufacturing2022,4,4: | 4 |
| 6 | 小麦秸秆发酵产生的真菌Pleurotus ostreatus IBL-02锰过氧化物酶的溶胶-凝胶固定化及其催化污水脱色(英文)显示文摘Solid state bio-processing of wheat straw was carried out through an indigenous fungal strain Pleurotus ostreatus IBL-02 under pre-optimized fermentation conditions. The maximum activity, 692±12 U/mL, of the industrially important manganese peroxidase (MnP) enzyme was recorded after five days of still culture incubation. The crude MnP was 2.1-fold purified with a specific activity of 860 U/mg after purification on a Sephadex-G-100 gel column. On native and SDS-PAGE electrophoresis gels, the purified MnP fraction was a single homogenous band of 45 kDa. An active fraction of MnP was immobilized using hydrophobic sol-gel entrapment comprising tetramethoxysilane (T) and propyltrimethoxysilane (P) at different T:P molar ratios. Characterization revealed that after 24 h incubation at varying pH and temperatures, the MnP fraction immobilized at a T:P ratio of 1:2 in the sol-gel retained 82% and 75% of its original activity at pH4 and 70 ℃, respectively. The optimally active fraction at a 1:2 T:P ratio was tested against MnSO4 as a substrate to determine the kinetic catalytic constants KM and Vmax . To explore the industrial applicability of P. ostreatus IBL-02 MnP, both the free and immobilized MnP were used for the decolorization of four different textile industrial effluents. A maximum of 100% decolorization was achieved for the different textile effluents within the shortest time period. A lower KM , higher Vmax , hyper-activation, and enhanced acidic and thermal resistance up to 70 ℃ were the novel catalytic features of the sol-gel immobilized MnP, suggesting that it may be a potential candidate for biotechnological applications particularly for textile bioremediation purposes. | Muhammad Asgher Bazgha Aslam Hafiz Muhammad Nasir Iqbal | 2013 | 催化学报2013,34,9: | 4 |
| 7 | Machinability of ultrasonic vibration-assisted micro-grinding in biological bone using nanolubricant显示文摘Bone grinding is an essential and vital procedure in most surgical operations.Currently,the insufficient cooling capacity of dry grinding,poor visibility of drip irrigation surgery area,and large grinding force leading to high grinding temperature are the technical bottlenecks of micro-grinding.A new micro-grinding process called ultrasonic vibration-assisted nanoparticle jet mist cooling(U-NJMC)is innovatively proposed to solve the technical problem.It combines the advantages of ultrasonic vibration(UV)and nanoparticle jet mist cooling(NJMC).Notwithstanding,the combined effect of multi parameter collaborative of U-NJMC on cooling has not been investigated.The grinding force,friction coefficient,specific grinding energy,and grinding temperature under dry,drip irrigation,UV,minimum quantity lubrication(MQL),NJMC,and U-NJMC micro-grinding were compared and analyzed.Results showed that the minimum normal grinding force and tangential grinding force of U-NJMC micro-grinding were 1.39 and 0.32 N,which were 75.1%and 82.9%less than those in dry grinding,respectively.The minimum friction coefficient and specific grinding energy were achieved using U-NJMC.Compared with dry,drip,UV,MQL,and NJMC grinding,the friction coefficient of U-NJMC was decreased by 31.3%,17.0%,19.0%,9.8%,and 12.5%,respectively,and the specific grinding energy was decreased by 83.0%,72.7%,77.8%,52.3%,and 64.7%,respectively.Compared with UV or NJMC alone,the grinding temperature of U-NJMC was decreased by 33.5%and 10.0%,respectively.These results showed that U-NJMC provides a novel approach for clinical surgical micro-grinding of biological bone. | Yuying YANG Min YANG Changhe LI Runze LI Zafar SAID Hafiz Muhammad ALI Shubham SHARMA | 2023 | Frontiers of Mechanical Engineering2023,18,1: | 3 |
| 8 | Fiber-reinforced composites in milling and grinding:machining bottlenecks and advanced strategies显示文摘Fiber-reinforced composites have become the preferred material in the fields of aviation and aerospace because of their high-strength performance in unit weight.The composite components are manufactured by near netshape and only require finishing operations to achieve final dimensional and assembly tolerances.Milling and grinding arise as the preferred choices because of their precision processing.Nevertheless,given their laminated,anisotropic,and heterogeneous nature,these materials are considered difficult-to-machine.As undesirable results and challenging breakthroughs,the surface damage and integrity of these materials is a research hotspot with important engineering significance.This review summarizes an up-to-date progress of the damage formation mechanisms and suppression strategies in milling and grinding for the fiber-reinforced composites reported in the literature.First,the formation mechanisms of milling damage,including delamination,burr,and tear,are analyzed.Second,the grinding mechanisms,covering material removal mechanism,thermal mechanical behavior,surface integrity,and damage,are discussed.Third,suppression strategies are reviewed systematically from the aspects of advanced cutting tools and technologies,including ultrasonic vibration-assisted machining,cryogenic cooling,minimum quantity lubrication(MQL),and tool optimization design.Ultrasonic vibration shows the greatest advantage of restraining machining force,which can be reduced by approximately 60%compared with conventional machining.Cryogenic cooling is the most effective method to reduce temperature with a maximum reduction of approximately 60%.MQL shows its advantages in terms of reducing friction coefficient,force,temperature,and tool wear.Finally,research gaps and future exploration directions are prospected,giving researchers opportunity to deepen specific aspects and explore new area for achieving high precision surface machining of fiber-reinforced composites. | Teng GAO Yanbin ZHANG Changhe LI Yiqi WANG Yun CHEN Qinglong AN Song ZHANG Hao Nan LI Huajun CAO Hafiz Muhammad ALI Zongming ZHOU Shubham SHARMA | 2022 | Frontiers of Mechanical Engineering2022,17,2: | 3 |
| 9 | Minimum quantity lubrication machining of aeronautical materials using carbon group nanolubricant: From mechanisms to application显示文摘It is an inevitable trend of sustainable manufacturing to replace flood and dry machining with minimum quantity lubrication(MQL)technology.Nevertheless,for aeronautical difficult-tomachine materials,MQL couldn’t meet the high demand of cooling and lubrication due to high heat generation during machining.Nano-biolubricants,especially non-toxic carbon group nano-enhancers(CGNs)are used,can solve this technical bottleneck.However,the machining mechanisms under lubrication of CGNs are unclear at complex interface between tool and workpiece,which characterized by high temperature,pressure,and speed,limited its application in factories and necessitates in-depth understanding.To fill this gap,this study concentrates on the comprehensive quantitative assessment of tribological characteristics based on force,tool wear,chip,and surface integrity in titanium alloy and nickel alloy machining and attempts to answer mechanisms systematically.First,to establish evaluation standard,the cutting mechanisms and performance improvement behavior covering antifriction,antiwear,tool failure,material removal,and surface formation of MQL were revealed.Second,the unique film formation and lubrication behaviors of CGNs in MQL turning,milling,and grinding are concluded.The influence law of molecular structure and micromorphology of CGNs was also answered and optimized options were recommended by considering diverse boundary conditions.Finally,in view of CGNs limitations in MQL,the future development direction is proposed,which needs to be improved in thermal stability of lubricant,activity of CGNs,controllable atomization and transportation methods,and intelligent formation of processing technology solutions. | Xin CUI Changhe LI Wenfeng Ding Yun CHEN Cong MAO Xuefeng XU Bo LIU Dazhong WANG Hao Nan LI Yanbin ZHANG Zafar SAID Sujan DEBNATH Muhammad JAMIL Hafiz Muhammad ALI Shubham SHARMA | 2022 | Chinese Journal of Aeronautics2022,35,11: | 3 |
| 10 | Multi-objective design optimization of composite submerged cylindrical pressure hull for minimum buoyancy and maximum buckling load capacity显示文摘This paper presents the design optimization of composite submersible cylindrical pressure hull subjected to 3 MPa hydrostatic pressure.The design optimization study is conducted for cross-ply layups[0_(s)/90_(t)/0_(u)],[0_(s)/90_(t)/0_(u)]s,[0_(s)/90_(t)]s and[90_(s)/0_(t)]s considering three uni-directional composites,i.e.Carbon/Epoxy,Glass/Epoxy,and Boron/Epoxy.The optimization study is performed by coupling a Multi-Objective Genetic Algorithm(MOGA)and Analytical Analysis.Minimizing the buoyancy factor and maximizing the buckling load factor are considered as the objectives of the optimization study.The objectives of the optimization are achieved under constraints on the Tsai-Wu,Tsai-Hill and Maximum Stress composite failure criteria and on buckling load factor.To verify the optimization approach,optimization of one particular layup configuration is also conducted in ANSYS with the same objectives and constraints. | Muhammad Imran Dong-yan Shi Li-li Tong Ahsan Elahi Hafiz Muhammad Waqas Muqeem Uddin | 2021 | Defence Technology(防务技术)2021,17,4: | 2 |
| 11 | Design optimization of composite egg-shaped submersible pressure hull for minimum buoyancy factor显示文摘This paper describes a design optimization study of the composite egg-shaped submersible pressure hull employing optimization and finite element analysis(FEA)tools as a first attempt to provide an optimized design of the composite egg-shaped pressure hull for manufacturing or further investigations.A total of 15 optimal designs for the composite egg-shaped pressure hull under hydrostatic pressure are obtained in terms of fibers’angles and the number of layers for 5 lay-up arrangements and 3 unidirectional(UD)composite materials.The optimization process is performed utilizing a genetic algorithm and FEA in ANSYS.The minimization of the buoyancy factor eB:FT is selected as the objective for the optimization under constraints on both material failure and buckling strength.Nonlinear buckling analysis is conducted for one optimal design considering both geometric nonlinearity and imperfections.A sensitivity study is also conducted to further investigate the influence of the design variables on the optimal design of the egg-shaped pressure hull. | Muhammad Imran Dongyan Shi Lili Tong Hafiz Muhammad Waqas Muqeem Uddin | 2021 | Defence Technology(防务技术)2021,17,6: | 2 |
| 12 | 尼龙66/针状硅灰石复合材料的制备和性能研究显示文摘以针状硅灰石为填料,用双螺杆挤出机共混制备尼龙(PA)66/硅灰石复合材料,研究了硅灰石含量、处理方法和加工工艺对复合材料性能的影响,并观察了硅灰石共混前后和PA66/硅灰石复合材料冲击试样断面的形貌。结果表明,硅灰石用KH–560预处理时比用KH–550预处理所制备的PA66/硅灰石复合材料的力学性能好。硅灰石以侧喂料方式加入并采用较低的螺杆转速时,可使复合材料具有较高的力学性能。随着硅灰石含量的增加,复合材料的拉伸强度、弯曲强度和缺口冲击强度都大幅提高。经过1%KH560预处理的硅灰石质量分数在30%时,PA66/硅灰石复合材料的力学性能最好。 | 陆波 王博识 Hafiz Muhammad Ramzan 李鹏 | 2013 | 工程塑料应用2013,41,7: | 2 |
| 13 | In Silico Screening of Natural Products as Potential Inhibitors of SARS-CoV-2 Using Molecular Docking Simulation显示文摘Objective:To explore potential natural products against severe acute respiratory syndrome coronavirus(SARS-CoV-2)via the study of structural and non-structural proteins of human coronaviruses.Methods:In this study,we performed an in-silico survey of 25 potential natural compounds acting against SARS-CoV-2.Molecular docking studies were carried out using compounds against 3-chymotrypsin-like protease(3 CL^(PHO)),papain-like protease(PL^(PRO)),RNA-dependent RNA polymerase(RdRp),non-structural protein(nsp),human angiotensin converting enzyme 2 receptor(hACE2 R),sapike glycoprotein(S protein),abelson murine leukemia viral oncogene homolog 1(ABL1),calcineurin-nuclear factor of activated T-cells(NFAT)and transmembrane protease serine 2.Results:Among the screened compounds,amentoflavone showed the best binding affinity with the 3 CL^(PRO),RdRp,nsp13,nsp15,hACE2 R,ABL1 and calcineurin-NFAT;berbamine with hACE2 R and ABL1;cepharanthine with nsp10,nsp14,nsp16,S protein and ABL1;glucogallin with nsp15;and papyriflavonol A with PL^(PRO)protein.Other good interacting compounds were juglanin,betulinic acid,betulonic acid,broussooflavan A,tomentin A,B and E,7-methoxycryptopleurine,aloe emodin,quercetin,tanshinone I,tylophorine and furruginol,which also showed excellent binding affinity towards a number of target proteins.Most of these compounds showed better binding affinities towards the target proteins than the standard drugs used in this study.Conclusion:Natural products or their derivatives may be one of the potential targets to fight against SARS-CoV-2. | Rajib Hossain Chandan Sarkar Shardar Mohammad Hafiz Hassan Rasel Ahmed Khan Mohammad Arman Pranta Ray Muhammad Torequl Islam Sevgi Durna Dastan Javad Sharifi-Rad Zainab M. Almarhoon Miquel Martorell William N. Setzer Daniela Calina | 2022 | Chinese Journal of Integrative Medicine2022,28,3: | 2 |
| 14 | Biological Stability of Water-Based Cutting Fluids:Progress and Application显示文摘The application of cutting fluid in the field of engineering manufacturing has a history of hundreds of years,and it plays a vital role in the processing efficiency and surface quality of parts.Among them,water-based cutting fluid accounts for more than 90%of the consumption of cutting fluid.However,long-term recycling of water-based cutting fluid could easily cause deterioration,and the breeding of bacteria could cause the cutting fluid to fail,increase manufacturing costs,and even endanger the health of workers.Traditional bactericides could improve the biological stability of cutting fluids,but they are toxic to the environment and do not conform to the development trend of low-carbon manufacturing.Low-carbon manufacturing is inevitable and the direction of sustainable manufacturing.The use of nanomaterials,transition metal complexes,and physical sterilization methods on the bacterial cell membrane and genetic material could effectively solve this problem.In this article,the mechanism of action of additives and microbial metabolites was first analyzed.Then,the denaturation mechanism of traditional bactericides on the target protein and the effect of sterilization efficiency were summarized.Further,the mechanism of nanomaterials disrupting cell membrane potential was discussed.The effects of lipophilicity and the atomic number of transition metal complexes on cell membrane penetration were also summarized,and the effects of ultraviolet rays and ozone on the destruction of bacterial genetic material were reviewed.In other words,the bactericidal performance,hazard,degradability,and economics of various sterilization methods were comprehensively evaluated,and the potential development direction of improving the biological stability of cutting fluid was proposed. | Lizhi Tang Yanbin Zhang Changhe Li Zongming Zhou Xiaolin Nie Yun Chen Huajun Cao Bo Liu Naiqing Zhang Zafar Said Sujan Debnath Muhammad Jamil Hafiz Muhammad Ali Shubham Sharma | 2022 | Chinese Journal of Mechanical Engineering2022,35,1: | 2 |
| 15 | Vegetable Oil-Based Nanolubricants in Machining:From Physicochemical Properties to Application显示文摘Cutting fluid is crucial in ensuring surface quality and machining accuracy during machining.However,traditional mineral oil-based cutting fluids no longer meet modern machining’s health and environmental protection require-ments.As a renewable,pollution-free alternative with excellent processing characteristics,vegetable oil has become an inevitable replacement.However,vegetable oil lacks oxidation stability,extreme pressure,and antiwear proper-ties,which are essential for machining requirements.The physicochemical characteristics of vegetable oils and the improved methods’application mechanism are not fully understood.This study aims to investigate the effects of viscosity,surface tension,and molecular structure of vegetable oil on cooling and lubricating properties.The mechanisms of autoxidation and high-temperature oxidation based on the molecular structure of vegetable oil are also discussed.The study further investigates the application mechanism and performance of chemical modification and antioxidant additives.The study shows that the propionic ester of methyl hydroxy-oleate obtained by epoxidation has an initial oxidation temperature of 175℃.The application mechanism and extreme pressure performance of conventional extreme pressure additives and nanoparticle additives were also investigated to solve the problem of insufficient oxidation resistance and extreme pressure performance of nanobiological lubricants.Finally,the study discusses the future prospects of vegetable oil for chemical modification and nanoparticle addition.The study provides theoretical guidance and technical support for the industrial application and scientific research of vegetable oil in the field of lubrication and cooling.It is expected to promote sustainable development in the manufacturing industry. | Xiaotian Zhang Changhe Li Zongming Zhou Bo Liu Yanbin Zhang Min Yang Teng Gao Mingzheng Liu Naiqing Zhang Zafar Said Shubham Sharma Hafiz Muhammad Ali | 2023 | Chinese Journal of Mechanical Engineering2023,36,4: | 2 |
| 16 | Curcumin preconditioning enhances the efficacy of adipose-derived mesenchymal stem cells to accelerate healing of burn wounds显示文摘Background:Following recent findings from our group that curcumin preconditioning augments the therapeutic efficacy of adipose-derived stem cells in the healing of diabetic wounds in rats,we aimed to investigate the regenerative effects of curcumin preconditioned adipose-derived mesenchymal stem cells(ASCs)for better recovery of acid inflicted burns in this study.Methods:ASCs were preconditioned with 5μM curcumin for 24 hours and assessed for proliferation,migration,paracrine release potential and gene expression comparative to naive ASCs.Subsequently,the healing capacity of curcumin preconditioned ASCs(Cur-ASCs)versus naive ASCs was examined using acidic wounds in rats.For this,acid inflicted burns of 20 mm in diameter were made on the back of male Wistar rats.Then,2×10^(6) cells of Cur-ASCs and naive ASCs were intradermally injected in the wound periphery(n=6)for comparison with an untreated saline control.Post-transplantation,wounds were macroscopically analysed and photographed to evaluate the percentage of wound closure and period of re-epithelization.Healed wound biopsies were excised and used for histological evaluation and expression analysis of wound healing markers at molecular level by quantitative PCR and western blotting.Results:We found that Cur-ASCs exhibited greater proliferation,migration and paracrine potential in vitro.Further,Cur-ASCs showed more effective recovery than naive ASCs as exhibited by gross morphology,faster wound closure and earlier re-epithelialization.Masson’s trichrome and hematoxylin and eosin staining demonstrated the improved architecture of the healing burns,as evidenced by reduced infiltration of inflammatory cells,compact collagen and marked granulation in Cur-ASC treated rats.Corroborating these findings,molecular assessment showed significantly reduced expressions of pro-inflammatory factors(interleukin-1 beta,interleukin-6,tumor necrosis factor alpha)a with striking upsurge of an oxidative marker(superoxide dismutase 1),proangiogenic factors(vascular endothelial growth factor,hepatocyte growth factor,hypoxia-inducible factor-1 alpha)and collagen markers(transforming growth factor beta 1,fibroblast growth factor-2,collagen type 1 alpha 1),verifying that Cur-ASCs modulate the regulation of pro-inflammatory and healing markers at burn sites.Conclusions:Treatment with Cur-ASCs resulted in faster re-epithelization of acid inflicted burns compared to the treatment with naive ASCs.Based on observed findings,we suggest the transplantation of Cur-ASCs is a valuable therapy for the potent clinical management of acidic burns. | Maryam Azam Hafiz Ghufran Hira Butt Azra Mehmood Ramla Ashfaq Asad M.Ilyas Muhammad R.Ahmad Sheikh Riazuddin | 2021 | Burns & Trauma2021,9,1: | 2 |
| 17 | Early selection of bread wheat genotypes using morphological and photosynthetic attributes conferring drought tolerance显示文摘Genetic diversity is the base of any genetic improvement breeding program aimed at stress breeding.The variability among breeding materials is of primary importance in the achievements of a good crop production.Herein,105 wheat genotypes were screened against drought stress using factorial completely randomized design at seedling stage to determine the genetic diversity and traits association conferring drought tolerance.Analysis of variances revealed that all the studied parameters differed significantly among all genotypes,indicating the significance genetic variability existed among all genotypes for studied indices.The 10 best performance genotypes G1,G6,G11,G16,G21,G26,G39,G44,G51,and G61 were screened as drought tolerant,while five lowest performance genotypes G3,G77,G91,G98,and G105 were screened as drought susceptible.Root length,chlorophyll a,chlorophyll b,and carotenoid contents were significantly correlated among themselves which exhibited the importance of these indices for rainfed areas in future wheat breeding scheme.Shoot length exhibited non-significant and negative association with other studied traits,and its selection seems not to be a promising criteria for this germplasm for drought stress.Best performance genotypes under drought stress conditions will be useful in future wheat breeding program and early selection will be effective for developing high yielding and drought tolerant wheat varieties. | Hafiz Ghulam Muhu-Din Ahmed Abdus Salam khan LI Ming-ju Sultan Habibullah Khan Muhammad Kashif | 2019 | Journal of Integrative Agriculture2019,18,11: | 2 |
| 18 | Concurrent dengue and malaria infection in Lahore, Pakistan during the 2012 dengue outbreak显示文摘 | Muhammad Zaman Khan Assir Muhammad Adnan Masood Hafiz Ijaz Ahmad | 2013 | International Journal of Infectious Diseases2013,,: | 1 |
| 19 | Investigations on the Effect of Electrical Contact Degradation on High Speed Wide-Band Signal Integrity显示文摘Electrical contact degradation will affect the signal integrity resulting in poor communication performance.In the present work,the effect of electrical contact degradation on wide-band digital signal integrity was studied using both the theoretical analysis and experimental testing.The characteristics of digital signals with rise times of 200 ps,400 ps,600 ps and 800 ps through connectors with different degradation levels were studied.The maximum bandwidth of these signals can reach up to 1.75 GHz.An equivalent model of the connector with degraded contact surface was developed and the experimental results are consistent with the model results approximately.The influence of capacitance characteristics caused by degraded contact surface on digital signal waveform was calculated and analyzed.The results of this paper are helpful in developing a better understanding of the characteristics of wide-band digital signal waveforms through the degraded contact surface and provide a theoretical support to identify failure features in fault diagnosis. | WANG Ziren GAO Jinchun JI Rui BILAL Hafiz Muhammad | 2020 | Chinese Journal of Electronics2020,29,3: | 1 |
| 20 | Perceived Social Support: Impact on Quality of Life in Diabetics 显示文摘 | Tahir Saeedl Nur Naha Abu Mansor Farah Naz Kaneez Fatima Hafiz Muhammad Ishaq | 2012 | International Journal of Academic Research2012,4,3: | 1 |