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| 1 | Free and forced vibrations of a simply supported rectangular plate partially embedded in an elastic foundation 显示文摘 | Daniel A Hilda L Patricio A A L | 1989 | Applied Acoustics1989，28，4： | 1 |
| 2 | Evolution of the western Pacific and its margin 显示文摘 | Hilda T W Uyeda C Kroewke L | 1977 | Tectonophysics1977，38，12： | 1 |
| 3 | Enrichment and Determination of Molybdenum in Geological Samples and Seawater by ICP-OES Using Calmagite and Activated Carbon显示文摘 | Hilda C Dos Santos Maria G A Korn Sergio L C Ferreira | 2001 | Anal Chim Acta2001，426，： | 1 |
| 4 | Characterization of a predominant immunogenic outer membrane protein of Riemerella anati pestifer 显示文摘 | SUMATHI S HUANG B HILDA L | 2000 | Clin Diagn Lab Immun2000，7，2： | 1 |
| 5 | Oral cavity and oropharynx tumors显示文摘 | HILDA ES SASAN K NANCY L | 2007 | Radiol Clin N Am2007，45，8： | 1 |
| 6 | Women and Politics显示文摘 | Smith Hilda L | 2006 | EighteenthCentury Studies2006，，39： | 1 |
| 7 | Growth and Survival of Heliothis virescences(Lepidoptera:Noctuidae) on transgenic cotton containing a truncated form of the Delta Endotoxin gene from Bacillus thuringiensis 显示文摘 | JENKINS HILDA L COLLINS RICHARD T ROUSH | 1993 | Jouranl of economic entomology1993，86，1： | 1 |
| 8 | Characterization of a predominant immunogenic outer membrane protein of Riemerella anatipestifer 显示文摘 | Sumathi S Huang B Hilda L | 2000 | Clin Diagn Lab Immunol2000，7，2： | 1 |
| 9 | In vitro clonal propagation of Vanilla planifolia显示文摘 | Hilda E L Joaquin M Benjamin G | 2008 | HortSeience2008，43，： | 1 |
| 10 | Development of an ELISA using a recombinant 41 ku partal protein(P45N') for the de tection of Riemerella anatipestifer infections in ducks显示文摘 | HUANG B JIMMY K HILDA L | 2002 | Vet Microbiol2002，88，4： | 1 |
| 11 | Co-expression of multiple transgenes in mouse CNS: a comparison of strategies显示文摘 | Joanna L Jankowsky Hilda H Slunt Tamara Ratovitski Nancy A Jenkins Neal G Copeland David R Borchelt | 2001 | Biomolecular Engineering2001，，6： | 1 |
| 12 | Satellite Based Estimates of Long-Term Exposure to Fine Particles and Association with Mortality in Elderly Hong Kong Residents显示文摘 | CHIT M W HAK K L HILDA T | 2015 | Environ Health Perspect2015，123，： | 1 |
| 13 | Enrichment and Determination of Molybdenum in Geological Samples and Seawater by ICP-AES Using Calmagite and Activated Carbon显示文摘 | Hilda C Dos Santos Maria G A Korn Sergio L C Ferreira | 2001 | Anal Chim Acta2001，426，： | 1 |
| 14 | Core Competencies for Shared Decision Making Training Programs: Insights From an International, Interdisciplinary Working Group显示文摘 | France Légaré Nora Moumjid‐Ferdjaoui Renée Drolet Dawn Stacey Martin H?rter Hilda Bastian Marie‐Dominique Beaulieu Francine Borduas Cathy Charles Angela Coulter Sophie Desroches Gwendolyn Friedrich Amiram Gafni Ian D. Graham Michel Labrecque Annie LeBlanc | 2013 | J. Contin. Educ. Health Prof2013，，4： | 1 |
| 15 | Aggregation properties of a therapeutic peptide for rheumatoid arthritis:A spectroscopic and molecular dynamics study显示文摘The biological properties of therapeutic peptides,such as their pharmacokinetics and pharmacodynamics,are correlated with their structure and aggregation properties.Herein,we studied the aggregation properties of a therapeutic peptide(CIGB-814),currently in phase 2 clinical trial,for the treatment of rheumatoid arthritis over a wide range of concentrations(μM-mM).We applied spectroscopic techniques(fluorescence,circular dichro-ism,resonance,and dynamic light scattering),atomic force microscopy,and molecular dynamics simulations to determine the aggregation mechanism of CIGB-814.We found that the hierarchical aggregation of CIGB-814 at micromolar concentrations was initiated by the formation of peptide oligomers.Subsequently,the peptide oligomers trigger the nucleation and growth of peptide nanostructures(cac=123μM),ultimately leading to the fibrillization of CIGB-814(cac’=508μM).These results pave the way for a deeper understanding of the CIGB-814 therapeutic activity and may give important insights on its pharmacokinetics. | Rita Cimino Marco Savioli Noemi Ferrante Carrante Ernesto Placidi Hilda Garay-Perez Matilde López-Abad Alexis Musacchio Lasa Maria Del Carmen Domínguez-Horta Emanuela Gatto Francesca Cavalieri Gianfranco Bocchinfuso Mariano Venanzi | 2022 | ChemPhysMater2022，1，1： | 0 |
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