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| 1 | Evaluation of antigenotoxic effects of carotenoids from green algae Chlorococcum humicola using human lymphocytes显示文摘Objective:To identify the available phytochemicals and carotenoids in the selected green algae and evaluate the potential genotoxic/antigenotoxic effect using lymphocytes.Methods:Organic,solvent extracts of Chlorococcum humicola(C.humicola)were used for the phytochemical analysis.The available carotenoids were assessed by HPLC,and LC-MS analysis.The genotoxicity was induced by the benzo(a)pyrene in the lymphocyte culture,the genotoxic and antigenotoxic effects of algal carotenoids with and without genotoxic inducer were evaluated by chromosomal aberration(CA),sister chromatid exchange(SCE)and micronucleus assay(MN).Results:The results of the analysis showed that the algae were rich in carotenoids and fatty acids.In the total carotenoids lutein,β-carotene andα-carotene were found to be present in higher concentration.The frequency of CA and SCE increased by benzo(a)pyrene were significantly decreased by the carotenoids(P<0.05 for CA,P<0.001 for SCE).The MN frequencies of the cells were significantly decreased by the treatment with carotenoids when compared with the positive controls(P<0.05).Conclusions:The findings of the present study demonstrate that,the green algae C.humicola is a rich source of bioactive compounds especially carotenoids which effectively fight against environmental genotoxic agents,the carotenoids itself is not a genotoxic substance and should be further considered for its beneficial effects. | Bhagavathy S Sumathi P | 2012 | Asian Pacific Journal of Tropical Biomedicine2012，2，2： | 3 |
| 2 | Experimental investiga- tion on waste heat recovery by refinery oil sludge incinera- tion using fluidised-bed technique 显示文摘 | Sankaran S Pandey S Sumathy K | 1998 | J Environ SciHealth Part A1998，33，5： | 1 |
| 3 | Coagulation of residue oil and suspended solid in palm oil mill effluent by chitosan,alum and PAC显示文摘 | Ahmad A L Sumathi S Hameed B H | 2006 | Chemical Engineering Journal2006，118，12： | 1 |
| 4 | Structures, energies and vibrational frequencies of dinitrogen pentoxide 显示文摘 | Parthiban S Raghunandan B N Sumathi R | 1996 | Journal of Molecular Structure ( Theochem)1996，367，： | 1 |
| 5 | Molecular fingerprinting of Riemerella anatipestifer by repetitive sequence PCR显示文摘 | HUANG B SUMATHI S KIM-LEE C | 1999 | Vet Microbiol1999，67，3： | 1 |
| 6 | Absorption isotherm models and properties of SO2 and NO removal by plam shell activated carbon supported with cerium (Ce/PSAC)显示文摘 | SUMATHI S BHATIA S LEE K T | | 0，，01： | 1 |
| 7 | Physi- co-chemical characteristics, nutritional quality and shelf-life of pearl millet based extrusion cooked sup- plementary foods显示文摘 | Sumathi A Ushakumari S R Malleshi N G | 2007 | International Journal of Food Sciences and Nutrition2007，58，5： | 1 |
| 8 | The application of a Delphi technique in the linear programming optimization of future renewable energy options for India显示文摘 | Iniyan S Sumathy K | | 0，，01： | 1 |
| 9 | Neural network based plant identification using leaf characteristics fusion 显示文摘 | SUMATHI C S KUMAR A V S | 2014 | International Journal of Computer Applications2014，89，5： | 1 |
| 10 | An optimal renewable energy model for various end-uses显示文摘 | INIYAN S SUMATHY K | 2000 | Energy2000，25，： | 1 |
| 11 | Uptake of reactive textile dyes by Aspergillus- foetidus 显示文摘 | SUMATHI S MANJU B S | 2000 | Enzyme & Microb Teehno12000，7，： | 1 |
| 12 | Selection of best impregnated palm shell activated carbon (PSAC) for simultaneous removal of SO2 and NOx显示文摘 | SUMATHI S BHATIA S LEE K T | | 0，，1： | 1 |
| 13 | Dynamic discovery of Web services using WSDL 显示文摘 | SUMATHI S CHIPLUNKAR N N ASHOK K A | 2014 | International journal of information technology and computer science2014，6，10： | 1 |
| 14 | Identification and characterization of cAMP cohemolysin as a potential virulence factor of Riemerella anatipestifer显示文摘 | KAREN C C CHUA K L SUMATHI S | 2002 | J Bacteriol2002，184，7： | 1 |
| 15 | Optimization of microporous palm shell activated carbon production for flue gas desulphurization: Experimental and statistical studies 显示文摘 | Sumathi S Bhatia S Lee K T | 2009 | Bioresource Technology2009，100，4： | 1 |
| 16 | Physico-chemical characteristics, nutritional quality and shelf-life of pearl millet based extrusion cooked supplementary foods显示文摘 | Sumathi A Ushakumari S R Malleshi N G | 2007 | International Journal of Food Sciences and Nutrition2007，58，5： | 1 |
| 17 | Selection of best impregnated palm'shell activated carbon(PSAC^3 for simultaneous removal of SO^2 and NOx显示文摘 | SUMATHI S BHATIA S LEE K T | 2010 | Journal of Hazardous Materials2010，176，： | 1 |
| 18 | Characterization of a predominant immunogenic outer membrane protein of Riemerella anati pestifer 显示文摘 | SUMATHI S HUANG B HILDA L | 2000 | Clin Diagn Lab Immun2000，7，2： | 1 |
| 19 | Molecular fingerprinting of Riemerella anatipestifer by repetitive sequence PCR显示文摘 | Huang B Sumathi S | | 0，，03： | 1 |
| 20 | Kinetic and equilibrium studies on the biosorption of reactive black 5 dye by Aspergillus foetidus显示文摘 | Rachna P Sumathi S | | 0，，： | 1 |
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