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| 1 | Auxin-induced AUXIN RESPONSE FACTOR4 activates APETALA1 and FRUITFULL to promote flowering in woodland strawberry显示文摘Flowering time is known to be regulated by numerous pathways,such as the autonomous,gibberellin,aging,photoperiod-mediated,and vernalization pathways.These regulatory mechanisms involve both environmental triggers and endogenous hormonal cues.Additional flowering control mechanisms mediated by other phytohormones,such as auxin,are less well understood.We found that in cultivated strawberry(Fragaria×ananassa),the expression of auxin response factor4(FaARF4)was higher in the flowering stage than in the vegetative stage.Overexpression of FaARF4 in Arabidopsis thaliana and woodland strawberry(Fragaria vesca)resulted in transgenic plants flowering earlier than control plants.In addition,FveARF4-silenced strawberry plants showed delayed flowering compared to control plants,indicating that FaARF4 and FveARF4 function similarly in regulating flowering.Further studies showed that ARF4 can bind to the promoters of the floral meristem identity genes APETALA1(AP1)and FRUITFULL(FUL),inducing their expression and,consequently,flowering in woodland strawberry.Our studies reveal an auxin-mediated flowering pathway in strawberry involving the induction of ARF4 expression. | Xiangxiang Dong Yanjun Li Yuhan Guan Shaoxi Wang He Luo Xiaoming Li He Li Zhihong Zhang | 2021 | Horticulture Research2021，8，1： | 4 |
| 2 | Searching for the Nano-Hertz Stochastic Gravitational Wave Background with the Chinese Pulsar Timing Array Data ReleaseⅠ显示文摘Observing and timing a group of millisecond pulsars with high rotational stability enables the direct detection of gravitational waves(GWs).The GW signals can be identified from the spatial correlations encoded in the times-of-arrival of widely spaced pulsar-pairs.The Chinese Pulsar Timing Array(CPTA)is a collaboration aiming at the direct GW detection with observations carried out using Chinese radio telescopes.This short article serves as a“table of contents”for a forthcoming series of papers related to the CPTA Data Release 1(CPTA DR1)which uses observations from the Five-hundred-meter Aperture Spherical radio Telescope.Here,after summarizing the time span and accuracy of CPTA DR1,we report the key results of our statistical inference finding a correlated signal with amplitude logA_(c)=-14.4_(-2.8)^(+1.0)for spectral index in the range ofα∈[-1.8,1.5]assuming a GW background(GWB)induced quadrupolar correlation.The search for the Hellings–Downs(HD)correlation curve is also presented,where some evidence for the HD correlation has been found that a 4.6σstatistical significance is achieved using the discrete frequency method around the frequency of 14 n Hz.We expect that the future International Pulsar Timing Array data analysis and the next CPTA data release will be more sensitive to the n Hz GWB,which could verify the current results. | Heng Xu Siyuan Chen Yanjun Guo Jinchen Jiang Bojun Wang Jiangwei Xu Zihan Xue RNicolas Caballero Jianping Yuan Yonghua Xu Jingbo Wang Longfei Hao Jingtao Luo Kejia Lee Jinlin Han Peng Jiang Zhiqiang Shen Min Wang Na Wang Renxin Xu Xiangping Wu Richard Manchester Lei Qian Xin Guan Menglin Huang Chun Sun Yan Zhu | 2023 | Research in Astronomy and Astrophysics2023，23，7： | 3 |
| 3 | Multi-platform omics analysis reveals molecular signature for COVID-19 pathogenesis,prognosis and drug target discovery显示文摘Disease progression prediction and therapeutic drug target discovery for Coronavirus disease 2019(COVID-19)are particularly important,as there is still no effective strategy for severe COVID-19 patient treatment.Herein,we performed multi-platform omics analysis of serial plasma and urine samples collected from patients during the course of COVID-19.Integrative analyses of these omics data revealed several potential therapeutic targets,such as ANXA1 and CLEC3B.Molecular changes in plasma indicated dysregulation of macrophage and suppression of T cell functions in severe patients compared to those in non-severe patients.Further,we chose 25 important molecular signatures as potential biomarkers for the prediction of disease severity.The prediction power was validated using corresponding urine samples and plasma samples from new COVID-19 patient cohort,with AUC reached to 0.904 and 0.988,respectively.In conclusion,our omics data proposed not only potential therapeutic targets,but also biomarkers for understanding the pathogenesis of severe COVID-19. | Yuming Li Guixue Hou Haibo Zhou Yanqun Wang Hein Min Tun Airu Zhu Jingxian Zhao Fei Xiao Shanwen Lin Dongdong Liu Dunrong Zhou Lang Mai Lu Zhang Zhaoyong Zhang Lijun Kuang Jiao Guan Qiushi Chen Liyan Wen Yanjun Zhang Jianfen Zhuo Fang Li Zhen Zhuang Zhao Chen Ling Luo Donglan Liu Chunke Chen Mian Gan Nanshan Zhong Jincun Zhao Yan Ren Yonghao Xu | 2021 | Signal Transduction and Targeted Therapy2021，6，5： | 1 |
| 4 | Career adaptability, job search self-efficacy and outcomes: A three-wave investigation among Chinese university graduates显示文摘 | Yanjun Guan Hong Deng Jiaqing Sun Yanan Wang Zijun Cai Lihui Ye Ruchunyi Fu Yang Wang Shu Zhang Yuhui Li | 2013 | Journal of Vocational Behavior2013，，3： | 1 |
| 5 | Lignocellulosic biomass gasification technology in China显示文摘 | Kai Zhang Jian Chang Yanjun Guan Honggang Chen Yongping Yang Jianchun Jiang | 2013 | Renewable Energy2013，，： | 1 |
| 6 | Servo motor control system based on free communication port 显示文摘 | Xiao Yanjun Guan Yuming | 2011 | IEEE2011，49，： | 1 |
| 7 | When do salary and job level predict career satisfaction and turnover intention among Chinese managers? The role of perceived organizational career management and career anchor显示文摘 | Yanjun Guan Yueran Wen Sylvia Xiaohua Chen Haiyang Liu Wei Si Yuhan Liu Yanan Wang Ruchunyi Fu Yuyan Zhang Zhilin Dong | 2014 | European Journal of Work and Organizational Psychology2014，，4： | 1 |
| 8 | Peptide with angiotensin 1-convertingenzymc inhibitory activity from hydrolyzed corn gluten meal 显示文摘 | Yang Yanjun Tao Guan Jun Liu Ping | 2007 | J Agri Food Chem2007，55，19： | 1 |
| 9 | Lignocellulosic biomass gasification technology in China显示文摘 | ZHANG Kai CHANG Jian GUAN Yanjun | | 0，，： | 1 |
| 10 | Out-group value incongruence and intergroup attitude: The roles of common identity and multiculturalism显示文摘 | Yanjun Guan Maykel Verkuyten Helene Hoi-lam Fung Michael Harris Bond Sylvia Xiaohua Chen Charles Ching-hai Chan | 2010 | International Journal of Intercultural Relations2010，，3： | 1 |
| 11 | Examining Stereotype Content Model in a Chinese context: Inter-group structural relations and Mainland Chinese’s stereotypes towards Hong Kong Chinese显示文摘 | Yanjun Guan Hong Deng Michael Harris Bond | 2010 | International Journal of Intercultural Relations2010，，4： | 1 |
| 12 | The In- terplay Between Social Cynicism Beliefs and Person - Orga- nization Fit on Work-Related Attitudes Among Chinese Em- ployees 显示文摘 | Hong Deng Yanjun Guan Michael Harris Bond etal | 2011 | Journal of Applied Social Psychology2011，41，1： | 1 |
| 13 | Responding to news about a natural disaster: The interplay of group identification and social cynicism in perceived prototypicality显示文摘 | Sylvia Xiaohua Chen Yanjun Guan Chin-Ming Hui | 2011 | International Journal of Intercultural Relations2011，，4： | 1 |
| 14 | Person-job fit and work-related attitudes among Chinese employees: need for cognitive closure as moderator 显示文摘 | GUAN Yanjun DENG Hong | 2010 | Basic and Applied Social Psychology2010，32，： | 1 |
| 15 | Visible light assisted enzyme-photocatalytic cascade degradation of organophosphorus pesticides显示文摘The worldwide application of organophosphorus pesticides(OPs)has promoted agricultural development,but their gradual accumulation in soil and water can seriously affect the central nervous system of humans and other mammals.Organophosphorus hydrolase(OPH)is an effective enzyme that can catalyze the degradation of the residual OPs.However,the degradation products such as p-nitrophenol(p-NP)is still toxic.Thus,it is of great significance to develop a multi-functional support that can be simultaneously used for the immobilization of OPH and the further degradation of p-NP.Herein,a visible light assisted enzyme-photocatalytic integrated catalyst was constructed by immobilizing OPH on hollow structured Au-TiO_(2)(named OPH@H-Au-TiO_(2))for the degradation of OPs.The obtained OPH@H-Au-TiO_(2)can degrade methyl parathion to p-NP by OPH and then degrade p-NP to hydroquinone with low toxicity by using H-Au-TiO_(2)under visible light.OPH molecules were immobilized on HAu-TiO_(2)through adsorption method to prepare OPH@H-Au-TiO_(2).After 2.5 h of reaction,methyl parathion is completely degraded,and about 82.64%of the generated p-NP is further degraded into hydroquinone.After reused for 4 times,the OPH@H-Au-TiO_(2)retains more than 80%of the initial degradation activity.This research presents a new insight in designing and constructing multi-functional biocatalyst,which greatly expands the application scenarios and industrial value of enzyme catalysis. | Ying Zhang Xue Cao Yufeng Yang Sumin Guan Xiaotian Wang Heyu Li Xiaobing Zheng Liya Zhou Yanjun Jiang Jing Gao | 2023 | Green Chemical Engineering2023，4，1： | 1 |
| 16 | A review and comparison of surface incident shortwave radiation from multiple data sources: satellite retrievals, reanalysis data and GCM simulations显示文摘Surface incident shortwave radiation(Rs)can promote the circulation of substance and energy,and the accuracy of its estimation is of great significance for climate studies.The Rs can be acquired from satellite retrievals,reanalysis predictions and general circulation model(GCM)simulations.Although Rs estimates have been evaluated and compared in previous studies,most of them focus on evaluating the Rs estimates over specific regions using ground measurements from limited stations.Therefore,it is essential to comprehensively validate Rs estimates from multiple data sources.In this study,ground measurements of 690 stations from BSRN,GEBA,CMA,GC-NET and buoys were employed to validate the Rs estimates from seven representative products(GLASS,GEWEX-SRB,CERES-EBAF,ERA5,MERRA2,CFSR and CMIP6).The validation results indicated that the selected products overestimated Rs globally,with biases ranged from 0.48 to 21.27 W/m^(2).The satellite retrievals showed relatively better accuracy among seven datasets compared to ground measurements at the selected stations.Moreover,the selected seven products were all in poor accuracy at high-latitude regions with RMSEs greater than 50 W/m^(2).The long-term variation trends were also analyzed in this study. | Shuyue Yang Xiaotong Zhang Shikang Guan Wenbo Zhao Yanjun Duan Yunjun Yao Kun Jia Bo Jiang | 2023 | International Journal of Digital Earth2023，16，1： | 1 |
| 17 | Hydrophobic Interface Cages in Microemulsions:Concept and Experiment Using Tetraphenylethylene-based Double-tailed Surfactant显示文摘Although hydrophobic interface regions adjacent to water droplets play a vital role in microemulsion-based studies,their widespread applications have not been explicitly evoked owing to their small spaces.Herein,we designed and synthesized a novel double-tailed anionic surfactant(TPE-di-C8SS)by linking the propeller-shaped tetraphenylethylene(TPE)with two octyl chains and an anionic sulfonate headgroup through a methoxy-butyl spacer.The extra spacer and steric hindrance between rigid TPE groups can create the large cavities in hydrophobic interface regions,which we call the hydrophobic interface cages(HICs).The potentials and advantages of HICs in the easily-prepared TPE-di-C8SS microemulsion have been implemented by comparing the extraction efficiency towards cationic rhodamine B with Aerosol OT(AOT)microemulsion.The results provided solid evidence that HICs rather than water droplets contributed to a higher extraction efficiency.This work not only proposes a concept of HICs but also provides a new perspective of their utilization in microemulsion-based applications. | GUAN Weijiang TANG Xiaofang WANG Wei LIN Yanjun LU Chao | 2021 | Chemical Research in Chinese Universities2021，37，1： | 0 |
| 18 | Computational investigation of contraction behavior in a liquid-solid fluidized bed显示文摘Contraction behavior of a liquid-solid fluidized bed has been investigated numerically. Based on a simple hydrodynamic model proposed by Brandani and Zhang (2006), a case study for solid particles with a density of 3,000 kg/m3 and a diameter of 2.5× 10 -3 m is simulated in a two-dimensional fluidized bed (0.50 m height and 0.10 m width). Due to the continuity of numerical computation, there is a transition region between two zones of different solid holdups when the liquid velocity is suddenly changed. The top, middle and bottom interfaces are explored to obtain a reasonable interface height. The simulated results show that the steady time of the middle interface is more close to Gibilaro's theory and suitable for describing the contraction process of a phase interface. Furthermore, the effect of liquid velocity and particle diameter is simulated in the other two-dimensional fluidized bed (0.10 m height and 0.02 m width) where the solid particles are glass beads whose properties are similar to those of the catalyst particles used in the alkylation process.The results also show good agreement with Gibilaro's theory, and that larger particles lead to a more obvious bed contraction. | Yao Xiuying Guan Yanjun Chang Jian Zhang Kai Jiang Jianchun | 2012 | Petroleum Science2012，9，1： | 0 |
| 19 | Dual-bionic regenerative microenvironment for peripheral nerve repair显示文摘Autologous nerve grafting serves is considered the gold standard treatment for peripheral nerve defects;however,limited availability and donor area destruction restrict its widespread clinical application.Although the performance of allogeneic decellularized nerve implants has been explored,challenges such as insufficient human donors have been a major drawback to its clinical use.Tissue-engineered neural regeneration materials have been developed over the years,and researchers have explored strategies to mimic the peripheral neural microenvironment during the design of nerve catheter grafts,namely the extracellular matrix(ECM),which includes mechanical,physical,and biochemical signals that support nerve regeneration.In this study,polycaprolactone/silk fibroin(PCL/SF)-aligned electrospun material was modified with ECM derived from human umbilical cord mesenchymal stem cells(hUMSCs),and a dual-bionic nerve regeneration material was successfully fabricated.The results indicated that the developed biomimetic material had excellent biological properties,providing sufficient anchorage for Schwann cells and subsequent axon regeneration and angiogenesis processes.Moreover,the dual-bionic material exerted a similar effect to that of autologous nerve transplantation in bridging peripheral nerve defects in rats.In conclusion,this study provides a new concept for designing neural regeneration materials,and the prepared dual-bionic repair materials have excellent auxiliary regenerative ability and further preclinical testing is warranted to evaluate its clinical application potential. | Yanjun Guan Zhiqi Ren Boyao Yang Wenjing Xu Wenjun Wu Xiangling Li Tieyuan Zhang Dongdong Li Shengfeng Chen Jun Bai Xiangyu Song Zhibo Jia Xing Xiong Songlin He Chaochao Li Fanqi Meng Tong Wu Jian Zhang Xiuzhi Liu Haoye Meng Jiang Peng Yu Wang | 2023 | Bioactive Materials2023，，8： | 0 |
| 20 | Hepatitis B Virus Induces Microtubule Stabilization to Promote Productive Infection through Upregulating Microtubule-associated Protein 1S显示文摘Background and Aims:Continuous release and transmission of hepatitis B virus(HBV)is one of the main factors leading to chronic hepatitis B(CHB)infection.However,the mechanism of HBV-host interaction for optimal viral transport is unclear.Hence,we aimed to explore how HBV manipulates microtubule-associated protein 1S(MAP1S)and microtubule(MT)to facilitate its transport and release.Methods:The expression of MAP1S or acetylated MT was investigated by immunofluorescence,RT-PCR,immunoblotting,and plasmid transfection.MAP1S overexpression or knockdown was performed by lentiviral infection or shRNA transfection,respectively.HBV DNA was quantified using q-PCR.Results:Significantly higher level of MAP1S in HepG2215 cells compared with HepG2 cells was detected using RT-PCR(p<0.01)and immunoblotting(p<0.001).Notably,stronger MAP1S expression was observed in the liver tissues of patients with CHB than in healthy controls.MAP1S overexpression or knockdown demonstrated that MAP1S promoted MT acetylation and reduced the ratio of HBV DNA copies inside to outside cells.Further,transfection with the hepatitis B virus X protein(HBx)-expressing plasmids induced significantly higher level of MAP1S than that in controls(p<0.0001),whereas HBVX−mutant-encoding HBV proteins(surface antigen,core protein,and viral DNA polymerase)hardly affected its expression.Conclusions:These results demonstrate that HBx induces the forma tion of stable MTs to promote the release of HBV particles through upregulating MAP1S.Thus,our studies delineate a unique molecular pathway through which HBV manipulates the cytoskeleton to facilitate its own transportation,and indicate the possibility of targeting MAP1S pathway for treatment of patients with CHB. | Yuanyue Guan Bin Sun Shijie Zhang Yuan Zhuang Yanxiang Huang Minghua Lin Rongling Zheng Dexi Chen Ying Shi Yanjun Wang | 2022 | Journal of Clinical and Translational Hepatology2022，10，3： | 0 |
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