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| 1 | 慢性病儿童应激源应对方式及心理状态的研究显示文摘目的在治疗慢性病儿童的同时,了解患儿的应激源、应对方式及心理状态,对于帮助他(她)们更好地应对慢性病的挑战、适应慢性病的状态是非常有帮助的。该研究旨在了解我国慢性病儿童的应激源、应对方式、心理状态及其影响因素,为儿科工作者提供信息,为临床干预提供依据。方法对203名8~16岁慢性病儿童进行调查,采用半结构访谈方式了解其应激源,采用CODI自评应对方式量表、儿童焦虑性情绪障碍筛查表(SCARED)、儿童抑郁障碍自评量表(DSRSC)了解其应对方式及焦虑、抑郁状态。结果①患儿应激源主要包括学习、疾病治疗、日常生活、与同学/伙伴关系4个方面。②患儿最常采用的应对方式是'幻想',其次是'接受','负性情绪反应'使用率最少。③慢性病儿童焦虑、抑郁量表得分均高于常模。被调查者中,43.8%患儿存在焦虑障碍,30.0%存在抑郁障碍,26.1%同时存在焦虑和抑郁障碍。结论慢性病儿童应激源较多,虽然相对较多采用积极应对方式,但其焦虑障碍和抑郁障碍仍比较普遍而且严重,应引起关注。 | 李杨 魏珉 Gayle PAGE Susan IMMELT | 2008 | 中国当代儿科杂志2008，10，3： | 29 |
| 2 | 对慢性病患儿及其父母教育干预的效果研究显示文摘目的评价针对慢性病患儿及其父母的教育干预措施的效果,为临床建立系统的针对慢性病患儿及其父母的教育干预项目提供依据。方法 50名慢性病患儿和75名慢性病患儿父母为研究对象。干预组为2007年8月至2008年1月住院的患儿及其父母,对照组为2007年2月~7月住院的患儿及其父母。患儿入院2d后开始教育干预,内容包括疾病知识、自我管理、用药知识和应对技巧等。在患儿出院前1天、出院后3个月时评价两组患儿及患儿父母的知识水平、应激源、应对方式、心理状态及服药依从性。结果教育干预后,干预组患儿父母及患儿的知识问卷得分均高于对照组(P<0.01),应激源数均低于对照组(P<0.01,P<0.05);干预组患儿父母'通过咨询和交流获取信息'的积极应对方式的使用频率高于对照组(P<0.05);但两组患儿用药依从性差异无统计学意义(P>0.05)。结论教育干预可以提高慢性病患儿及父母疾病知识水平,减少患儿及父母的应激源数,使父母更多地采用积极的应对方式,但对改善患儿及父母的焦虑、抑郁状态无明显作用。 | 李杨 魏珉 Gayle PAGE Susan IMMELT 鲁重美 | 2010 | 中国当代儿科杂志2010，12，6： | 13 |
| 3 | 慢性病患儿父母应激源、应对方式、心理状态及其影响因素的研究显示文摘目的了解慢性病患儿父母的应激源、应对方式、心理状态及其影响因素,为临床工作者提供信息,为临床干预提供依据。方法对280名慢性病儿童父母进行调查,采用半结构访谈方式了解其应激源,采用CHIP应对方式量表、Zung焦虑自评量表(SAS)和Zung抑郁自评量表(SDS)了解其应对方式、焦虑、抑郁状态。结果患儿父母应激源主要包括6个方面:患儿病情及身体状况、疾病治疗、经济方面、照顾患儿方面、角色功能及沟通交流。父母采用的积极应对方法比较局限,更多集中在为患儿寻求和维持更好的疾病治疗方面,而忽视了其自身的心理调节和寻求社会支持。58.6%的父母存在焦虑,56.8%存在抑郁,49.6%的父母同时存在焦虑和抑郁。父母应激源越多压力程度越大,采用积极应对方式的频率越少,焦虑和抑郁程度越重;良好的心理状态与其积极的应对方式呈正相关。结论慢性病患儿父母应激源较多,压力较大,对积极的应对方式的选择还比较局限,心理问题也较严重,应引起重视。 | 李杨 魏珉 Gayle Page Susan Immelt | 2010 | 中华现代护理杂志2010，16，5： | 12 |
| 4 | 氧化硅去除微囊藻毒素显示文摘考察了氧化硅对微囊藻毒素—LR (Microcystin LR ,MLR)和—LA (Microcystin LA ,MLA)的等温吸附行为 ,并通过微观结构分析和红外吸收光谱对其机理进行了研究。结果表明 :氧化硅对MLR和MLA有着良好的吸附作用 ,吸附率随氧化硅含量的增加而提高 ;同等条件下 ,氧化硅对分子质量较低的MLA具有明显的吸附倾向性 ;氧化硅的吸附能力不仅依赖于其突出的微观结构 ,分布于表面上的大量化学“活性”基团———“自由振动”羟基在吸附过程中同样发挥着相当重要的作用。 | 赵亮 Gayle Newcombe Leanne Britcher | 2004 | 中国给水排水2004，20，2： | 6 |
| 5 | Self-perceptions and social–emotional classroom engagement following structured physical activity among preschoolers: A feasibility study显示文摘Background: The well-rounded development of the child, including physical, cognitive, emotional, and social health, may be the most efficient route to well-being and academic success. The primary goal was to investigate the feasibility of implementing a 12-week structured program of physical activity(PA) incorporating cognitive, social, and emotional elements in preschool. Additionally, this study, using a within-subject design,examined the acute effects of a PA session on classroom engagement and changes on perceived competence and peer acceptance from the first to the last week of the program.Methods: Twenty-seven preschoolers(mean age = 4.2 years) completed the Pictorial Scale of Perceived Competence and Social Acceptance for Young Children before and after a twice-weekly PA program. Unobtrusive classroom observations were conducted for verbal, social, and affective engagement during the first and last week of the program, both following a structured PA session(experimental day) and on a day without PA(control day). Treatment fidelity was monitored to ensure that the intervention was delivered as designed.Results: The children exhibited longer periods of verbal and social engagement during classroom periods that followed PA sessions than on non-PA days. Children also expressed more positive affect following PA sessions during the last week of the PA program. Despite high baseline scores,perceptions of general competence increased meaningfully(η2= 0.15, p = 0.05), driven by increase in perceptions of cognitive competence(η2= 0.15,p = 0.06).Conclusion: This study demonstrates the feasibility of providing structured PA program to preschoolers. Moreover, these initial findings suggest that purposely designed, structured PA may help advance the social–emotional engagement and perceived competence of preschool children. | Spyridoula Vazou Constantine Mantis Gayle Luze Jacqueline S.Krogh | 2017 | Journal of Sport and Health Science2017，6，2： | 5 |
| 6 | 一氧化氮在神经退行性疾病中的作用:非类固醇性抗炎药的治疗前景(英文)显示文摘一氧化氮(nitric oxide, NO)是一类胞内信使。研究表明,神经退行性病人脑组织中催化合成NO的酶的表达水平显著提高,提示NO与神经退行性疾病密切相关。此外,在这些组织中还检测到硝化的蛋白,提示NO在这些组织中具有生物活性。在神经免疫应答中,神经元和胶质细胞(包括小胶质细胞和星形胶质细胞)内都发生了NO水平的改变。很多神经退行性疾病都伴随有神经炎症,抑制神经炎症的信号通路能延迟这些疾病的发展。因此,NO及其释放通路已逐渐成为神经退行性疾病研究领域的热点,对它们的理解能帮助我们找到合适的方案来预防、减缓或者治愈这些疾病。 | Gayle Helane Doherty | 2011 | Neuroscience Bulletin2011，27，6： | 4 |
| 7 | Chinese students’ perceptions of ESL peer response group interaction显示文摘 | Joan G. Carson Gayle L. Nelson | 1996 | Journal of Second Language Writing1996，，1： | 4 |
| 8 | ESL students’ perceptions of effectiveness in peer response groups显示文摘 | Gayle L. Nelson Joan G. Carson | 1998 | Journal of Second Language Writing1998，，2： | 4 |
| 9 | 父母物质滥用和精神疾病对青少年精神疾病的影响显示文摘 | 赵敏 Arlene Frank Gayle Dakof Howard Liddle | 2004 | 中国药物依赖性杂志2004，13，2： | 3 |
| 10 | 微囊藻毒素-LR的特征红外光谱显示文摘利用傅里叶变换红外(FTIR)光谱仪研究了微囊藻毒素-LR在扫描范围4000-600cm^-1的红外吸收光谱图,微囊藻毒素-LR分子构成中的主要官能团,如带有单一取代基的苯环、胍基、γ-羧基等特征红外吸收带在谱图上均得到了确认。 | 赵亮 Gayle Newcombe Leanne Britcher | 2006 | 光谱学与光谱分析2006，26，6： | 3 |
| 11 | Significance of inferior wall ischemia in non-dominant right coronary artery anatomy显示文摘AIM To investigate the relationship of inferior wall ischemia on myocardial perfusion imaging in patients with nondominant right coronary artery anatomy.METHODS This was a retrospective observational analysis of consecutive patients who presented to the emergency department with primary complaint of chest pain.Only patients who underwent single photon emission computed tomography(SPECT)myocardial perfusion imaging(MPI)were included.Patients who showed a reversible defect on SPECT MPI and had coronary angiography during the same hospitalization was analyzed.Patients with prior history of coronary artery disease(CAD)including history of percutaneous coronary intervention and coronary artery bypass graft surgerys were excluded.True positive and false positive results were identified on the basis of hemodynamically significant CAD on coronary angiography,in the same territory as identified on SPECT MPI.Coronary artery dominance was determined on coronary angiography.Patients were divided into group 1 and group 2.Group1 included patients with non-dominant right coronary artery(RCA)(left dominant and codominant).Group2 included patients with dominant RCA anatomy.Demographics,baseline characteristics and positive predictive value(PPV)were analyzed for the two groups.RESULTS The mean age of the study cohort was 57.6 years.Sixtyone point seven percent of the patients were males.The prevalence of self-reported diabetes mellitus,hypertension and dyslipidemia was 36%,71.9%and 53.9%respectively.A comparison of baseline characteristics between the two groups showed that patients with a non-dominant RCA were more likely to be men.For inferior wall ischemia on SPECT MPI,patients in study group 2 had a significantly higher PPV,32/42(76.1%),compared to patients in group 1,in which only 3 out of the 29 patients(10.3%)had true positive results(P value<0.001 Z test).The difference remained statistically significant even when only patients with left dominant coronary system(without co-dominant)were compared to patients with right dominant system(32/40,76.1%in right dominant group,3/19,15.8%in left dominant group,P value<0.001 Z test).There was no significant difference in mean hospital stay,re-hospitalization,and in-hospital mortality between the two groups.CONCLUSION The positive predictive value of SPECT MPI for inferior wall ischemia is affected by coronary artery dominance.More studies are needed to explain this phenomenon. | Ali Osama Malik Oliver Abela Subodh Devabhaktuni Arhama Aftab Malik Gayle Allenback Chowdhury H Ahsan Sanjay Malhotra Jimmy Diep | 2017 | World Journal of Cardiology2017，9，3： | 2 |
| 12 | CXCR4-mediated adhesion and MMP-9 secretion in head and neck squamous cell carcinoma显示文摘 | Ghassan J. Samara Diana M. Lawrence Christian J. Chiarelli Michael D. Valentino Sergey Lyubsky Stanley Zucker Gayle G. Vaday | 2004 | Cancer Letters2004，，2： | 2 |
| 13 | Dermal excisional wound healing in pigs following treatment with topically applied pure oxygen显示文摘 | Richard B. Fries William A. Wallace Sashwati Roy Periannan Kuppusamy Valerie Bergdall Gayle M. Gordillo W. Scott Melvin Chandan K. Sen | 2005 | Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis2005，，1： | 2 |
| 14 | Revisiting the essential role of oxygen in wound healing显示文摘 | Gayle M Gordillo Chandan K Sen | 2003 | The American Journal of Surgery2003，，3： | 2 |
| 15 | Insights into platinum-induced peripheral neuropathy–current perspective显示文摘Cancer is a global health problem that is often successfully addressed by therapy, with cancer survivors increasing in numbers and living longer world around. Although new cancer treatment options are continuously explored, platinum based chemotherapy agents remain in use due to their efficiency and availability. Unfortunately, all cancer therapies affect normal tissues as well as cancer, and more than 40 specific side effects of platinum based drugs documented so far decrease the quality of life of cancer survivors. Chemotherapy-induced peripheral neuropathy is a frequent side effects of platinum-based chemotherapy agents. This cluster of complications is often so debilitating that patients occasionally have to discontinue the therapy. Sensory neurons of dorsal root ganglia are at the core of chemotherapy-induced peripheral neuropathy symptoms. In these postmitotic cells, DNA damage caused by platinum chemotherapy interferes with normal functioning. Accumulation of DNA-platinum adducts correlates with neurotoxic severity and development of sensation of pain. While biochemistry of DNA-platinum adducts is the same in all cell types, molecular mechanisms affected by DNA-platinum adducts are different in cancer cells and non-dividing cells. This review aims to raise awareness about platinum associated chemotherapy-induced peripheral neuropathy as a medical problem that has remained unexplained for decades. We emphasize the complexity of this condition both from clinical and mechanistical point of view and focus on recent findings about chemotherapy-induced peripheral neuropathy in in vitro and in vivo model systems. Finally, we summarize current perspectives about clinical approaches for chemotherapy-induced peripheral neuropathy treatment. | Andrijana Lazić Jelena Popović Tatjana Paunesku Gayle EWoloschak Milena Stevanović | 2020 | Neural Regeneration Research2020，15，9： | 2 |
| 16 | Gibberellic acid-induced cell elongation in cotton suspension cultures显示文摘 | Gayle H. Davidonis | 1990 | Journal of Plant Growth Regulation (-)1990，，1： | 2 |
| 17 | Manganese superoxide dismutase interacts with a large scale of cellular and mitochondrial proteins in low-dose radiation-induced adaptive radioprotection显示文摘 | Angela Eldridge Ming Fan Gayle Woloschak David J. Grdina Brett A. Chromy Jian Jian Li | 2012 | Free Radical Biology and Medicine2012，，10： | 1 |
| 18 | Understanding the relationship of perceived social support to post-trauma cognitions and posttraumatic stress disorder显示文摘 | Donald J. Robinaugh Luana Marques Lara N. Traeger Elizabeth H. Marks Sharon C. Sung J. Gayle Beck Mark H. Pollack Naomi M. Simon | 2011 | Journal of Anxiety Disorders2011，，8： | 1 |
| 19 | Adipose tissue-derived tumor necrosis factor activity correlates with fat cell size but not insulin action in aging rats显示文摘 | Morin CL Gayles EC Podolin DA | 1998 | Endocrinology1998，139，12： | 1 |
| 20 | Learning strategies and navigation decisions of children using a hypermedia lesson显示文摘 | Gayle V D Shorter L Jordan K | 1999 | Journal of Educational Multimedia and Hypermedia1999，8，2： | 1 |
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