|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | 2018加拿大心境障碍与焦虑障碍治疗协作组/国际双相障碍学会指南:双相障碍的管理显示文摘加拿大心境障碍与焦虑障碍治疗协作组(Canadian Network for Mood and Anxiety Treatments,CANMAT)曾于2005年发布了第1版双相障碍管理指南,并分别于2007、2009和2013年对该指南进行了更新,其中最近的2次更新是与国际双相障碍学会(International Society for Bipolar Disorders,ISBD)合作完成。2018版CANMAT/ISBD双相障碍治疗指南(以下简称指南)反映了自2005年首版指南发表以来本领域取得的重大进展,包括疾病诊断与疾病管理的更新以及药物治疗与心理治疗的近期研究进展。这些前沿进展中综合考虑了循证证据的级别,并基于治疗疗效、临床实践经验、安全性、耐受性和药物导致的转相风险等,对一线、二线及三线治疗方案进行了简明而清晰的推荐。本指南中新增内容涵盖了双相Ⅰ型障碍(BD-Ⅰ)的躁狂发作急性期、抑郁发作急性期和双相障碍维持期的一线及二线治疗推荐等级划分。这种对治疗推荐等级的划分综合考虑了治疗方法对双相障碍不同时相的影响,将进一步帮助临床医生做出基于循证证据的治疗决策。锂盐、喹硫平、双丙戊酸盐、阿塞那平、阿立哌唑、帕利哌酮、利培酮和卡利拉嗪单药或联合使用被推荐为躁狂发作急性期的一线治疗选择。BD-Ⅰ抑郁期的一线治疗选择包括喹硫平、鲁拉西酮、锂盐、拉莫三嗪单药,鲁拉西酮联合锂盐或双丙戊酸盐或拉莫三嗪辅助治疗。尽管急性期治疗有效的药物通常应继续用于BD-Ⅰ的维持期治疗,但也存在一些特殊情况(例如抗抑郁药)。现有数据表明,锂盐、喹硫平、双丙戊酸盐、拉莫三嗪、阿塞那平和阿立哌唑单药或联合治疗应被视为维持治疗的初始或更换治疗方案时的一线选择。除了探讨BD-Ⅰ的相关问题外,本指南中还对双相Ⅱ型障碍(BD-Ⅱ)的临床管理进行了系统回顾并给予治疗推荐,同时针对特殊人群也有相关推荐,如处于各个生殖周期的女性、儿童、青少年和老年人。此外,本指南中还讨论了特定精神疾病及共病(如物质滥用、焦虑障碍和代谢性疾病)的影响。最后,本指南中概述了安全性和药物监测的相关问题。CANMAT/ISBD工作组希望本指南能够成为全球临床医生的实用工具。 | Lakshmi N Yatham Sidney H Kennedy Sagar V Parikh Ayal Sehaffer David J Bond Benicio N Frey Verinder Sharma Benjamin I Goldstein Soham Rej Serge Beaulieu Martin Alda Glenda MaeQueen Roumen V Milev Arun Ravindran Claire O'Donovan Diane Mclntosh Raymond W Lam Gustavo Vazquez Flavio Kapczinski Roger S Melntyre Jan Kozicky Shigenobu Kanba Beny Lafer Trisha Suppes Joseph R Calabrese Eduard Vieta Gin Malhi Robert M Post Michael Berk 胡晨(译) 王刚(译) | 2019 | 中华精神科杂志2019，52，1： | 25 |
| 2 | 肝移植治疗原发性胆汁性肝硬化的疗效分析显示文摘目的 观察原发性胆汁性肝硬化(PBC)患者和移植肝的实际生存时间,肝移植后死亡的原因及肝移植后的复发率。 方法 根据QLTS的数据库中的随访资料,回顾性分析52例共接受54次肝移植的PBC患者。52例PBC肝移植患者中,平均年龄(5 3.2±6.7)岁,平均随访时间是(5 5.4±11.3)个月。分析术前的临床特征、移植后生存情况和死亡原因,采用欧洲模式计算未接受肝移植患者和接受肝移植的患者的生存率。 结果 PBC肝移植患者的1、5、1 0年的实际生存率分别为8 8.4%、80.1%和76.9%,未接受肝移植患者实际生存率分别为80.9%、6 5.4%和19.8%。PBC患者移植后的生存率比未接受肝移植的患者(欧洲模型)预期生存率高。有6例患者经肝活检后证实PBC复发,平均复发时间(34.1±10.2)个月。肝移植术后死亡的原因是多器官功能衰竭、腹腔内出血、肾功能衰竭、败血症及心血管疾病。 结论 肝移植可提高P B C患者的生存率,延长其生存时间。 | 许崇恩 Stephen V.Lynch Glenda A.Balderson Jonathan Fawcett Russell W Strong Shinn Yeong | 2004 | 中华肝脏病杂志2004，12，9： | 6 |
| 3 | 额颞叶痴呆显示文摘一、前言
额颞叶痴呆(frontotemporal dementia,FFD)是一组临床痴呆症候群,由前额叶和颞叶变性引起,其病理表现与阿尔茨海默病(AD)不同,病理上称之为额颞叶变性(frontotemporal lobe degeneration,FTLD)。以往临床上也称为皮克病(Pick disease)。 | 黄越 Glenda Halliday 陈生弟 John Hodges | 2008 | 中华神经科杂志2008，41，12： | 4 |
| 4 | Brain Banking for Research into Neurodegenerative Disorders and Ageing显示文摘Advances in cellular and molecular biology underpin most current therapeutic advances in medicine.Such advances for neurological and neurodegenerative diseases are hindered by the lack of similar specimens. It is becoming increasingly evident that greater access to human brain tissue is necessary to understand both the cellular biology of these diseases and their variation. Research in these areas is vital to the development of viable therapeutic options for these currently untreatable diseases. The development and coordination of human brain specimen collection through brain banks is evolving. This perspective article from the Sydney Brain Bank reviews data concerning the best ways to collect and store material for different research purposes. | Claire E.Shepherd Holly Alvendia Glenda M.Halliday | 2019 | Neuroscience Bulletin2019，35，2： | 3 |
| 5 | Comparative efficacy of sorafenib versus best supportive care in recurrent hepatocellular carcinoma after liver transplantation: A case-control study<.-- Doctopic: TAS -->显示文摘 | Carlo Sposito Luigi Mariani Alessandro Germini Maria Flores Reyes Marco Bongini Glenda Grossi Sherrie Bhoori Vincenzo Mazzaferro | 2013 | Journal of Hepatology2013，，1： | 3 |
| 6 | DNA extraction from fresh-frozen and formalin-fixed, paraffinembedded human brain tissue显示文摘Both fresh-frozen and formalin-fixed,paraffinembedded(FFPE)human brain tissues are invaluable resources for molecular genetic studies of central nervous system diseases,especially neurodegenerative disorders.To identify the optimal method for DNA extraction from human brain tissue,we compared methods on differently-processed tissues.Fragments of LRRK2 and MAPT(257 bp and 483 bp/245 bp)were amplified for evaluation.We found that for FFPE samples,the success rate of DNA extraction was greater when using a commercial kit than a laboratory-based method(successful DNA extraction from 76%versus 33%of samples).PCR amplicon size and storage period were key factors influencing the success rate of DNA extraction from FFPE samples.In the fresh-frozen samples,the DNA extraction success rate was 100%using either a commercial kit(QIAamp DNA Micro)or a laboratorybased method(sample boiling in 0.1 mol/L NaOH,followed by proteinase K digestion,and then DNA extraction using Chelex-100)regardless of PCR amplicon length or tissue storage time.Although the present results demonstrate that PCR-amplifiable genomic DNA can be extracted from both fresh-frozen and FFPE samples,fresh brain tissue is recommended for DNA extraction in future neuropathological studies. | Jian-Hua Wang Amany Gouda-Vossos Nicolas Dzamko Glenda Halliday Yue Huang | 2013 | Neuroscience Bulletin2013，29，5： | 3 |
| 7 | 化工公司应重视企业社会责任显示文摘社会责任投资(Socially Responsible Investing,简称SRI)是一个正在发展的投资领域并得到越来越多的重视。本文介绍了化工公司在社会责任投资上作出的努力,并以此评估化工公司的企业责任。 | Glenda Thisdell | 2003 | 化工文摘2003，，8： | 3 |
| 8 | Can we clinically diagnose dementia with Lewy bodies yet?显示文摘Dementia with Lewy Bodies(DLB)was initially identified and confirmed primarily by pathology,but is soon to be incorporated into the Diagnostic and Statistical Manual criteria as a clinical disease entity.Despite these advances over more than 20 years,current data suggest that the sensitivity of accurate clinical diagnosis of DLB is still very low,although there is mounting evidence that supportive features may increase diagnostic accuracy.Although DLB remains easy to identify pathologically with different cellular pathologies differentiating it from other dementia syndromes,pathological identification using only Lewy body pathology has been shown to be inaccurate due to overlap with patients without dementia symptoms.A number of studies now suggest that a combination of cellular pathologies,which include α-synuclein and β-amyloid deposition as well as dopamine denervation,assist with differentiating this dementia syndrome from others.The clinical and pathological overlap with the tauopathy of Alzheimer’s disease still remains to be clarified.To determine more robust and independent clinicopathological correlates from Alzheimer’s disease,longitudinal prospective studies,using specific clinical batteries on dementia patients reaching the proposed criteria for DLB,with post-mortem assessment of the multiple pathologies associated with dementia,are required.Identifying genetic causes for DLB is another approach to investigate the pathogenesis of DLB.However this approach has been hindered to date by difficulties with identifying DLB clinically.The use of novel techniques is likely to advance knowledge on the pathogenesis of DLB and assist with redefining clinical and pathologic diagnostic criteria.To achieve the goal of more accurate clinical diagnosis of DLB,breakthroughs are necessary on the pathogenesis of DLB. | Yue Huang Glenda Halliday | 2013 | Translational Neurodegeneration2013，2，1： | 2 |
| 9 | Relationship between head and neck cancer therapy and some genetic endpoints显示文摘Head and neck cancer(HNC) is the sixth most common human malignancy worldwide. The main forms of treat ment for HNC are surgery, radiotherapy(RT) and che motherapy(CT). However, the choice of therapy de pends on the tumor staging and approaches, which are aimed at organ preservation. Because of systemic RT and CT genotoxicity, one of the important side effects is a secondary cancer that can result from the activity of radiation and antineoplastic drugs on healthy cells Ionizing radiation can affect the DNA, causing single and double-strand breaks, DNA-protein crosslinks and oxidative damage. The severity of radiotoxicity can be directly associated with the radiation dosimetry and the dose-volume differences. Regarding CT, cisplatin is stil the standard protocol for the treatment of squamous cell carcinoma, the most common cancer located in theoral cavity. However, simultaneous treatment with cisplatin, bleomycin and 5-fluorouracil or treatment with paclitaxel and cisplatin are also used. These drugs can interact with the DNA, causing DNA crosslinks, double and single-strand breaks and changes in gene expression. Currently, the late effects of therapy have become a recurring problem, mainly due to the increased survival of HNC patients. Herein, we present an update of the systemic activity of RT and CT for HNC, with a focus on their toxicogenetic and toxicogenomic effects. | Eliana Maria Minicucci Glenda Nicioli da Silva Daisy Maria Fávero Salvadori | 2014 | World Journal of Clinical Oncology2014，5，2： | 2 |
| 10 | Is “service with a smile” enough? Authenticity of positive displays during service encounters显示文摘 | Alicia A. Grandey Glenda M. Fisk Anna S. Mattila Karen J. Jansen Lori A. Sideman | 2004 | Organizational Behavior and Human Decision Processes2004，，1： | 2 |
| 11 | Total tumor volume and alpha‐fetoprotein for selection of transplant candidates with hepatocellular carcinoma: A prospective validation显示文摘 | Christian Toso Glenda Meeberg Roberto Hernandez‐Alejandro Jean‐Fran?ois Dufour Paul Marotta Pietro Majno Norman M. Kneteman | 2015 | Hepatology2015，，1： | 2 |
| 12 | Up Close: Family Therapy Challenges and Innovations Around the World显示文摘 | Janine Roberts Khawla Abu‐Baker Cristina Diez Fernández Nelly Chong Garcia Glenda Fredman Hugo Kamya Yolanda Martín Higarza Jacqueline Fortes de Leff Philip Messent Shin‐Ichi Nakamura Fatma Torun Reid Timothy Sim Chitra Subrahmanian Roxana Zevallos Vega | 2014 | Fam. Proc2014，，： | 2 |
| 13 | Comparative efficacy of sorafenib versus best supportive care in recurrent hepatocellular carcinoma after liver transplantation: A case-control study显示文摘 | Carlo Sposito Luigi Mariani Alessandro Germini Maria Flores Reyes Marco Bongini Glenda Grossi Sherrie Bhoori Vincenzo Mazzaferro | 2013 | Journal of Hepatology2013，，1： | 2 |
| 14 | Volatile profile of Atlantic shellfish species by HS-SPME GC/MS显示文摘 | Glenda Fratini Salomé Lois Manuel Pazos Giuliana Parisi Isabel Medina | 2012 | Food Research International2012，，2： | 2 |
| 15 | Surgery for Thyroid Cancer显示文摘 | Glenda G. Callender Tobias Carling Emily Christison-Lagay Robert Udelsman | 2014 | Endocrinology and Metabolism Clinics of North America2014，，： | 2 |
| 16 | 非典型性帕金森样病显示文摘非典型性帕金森样病亦称帕金森综合征,为一组临床表现多样的疾病症候群,除了覆盖原发性帕金森病(PD)的主要临床症状[静止性震颤、肌强直、运动不能和(或)运动迟缓、姿势反射障碍外,还具有进展迅速、对左旋多巴反应不佳或其他特征性表现,如疾病早期易跌倒。 | 黄越 陈生弟 Gregor Wenning Lawrence Golbe 王少石 王拥军 赵钢 吕佩源 陈彪 Jun Yu Christine Song Andrew Lees Irene Litvan 王晓民 Glenda Halliday | 2011 | 中国现代神经疾病杂志2011，11，1： | 2 |
| 17 | The effect of vaccination against Porcine reproductive and respiratory syndrome virus (PRRSV) on the Porcine circo- virus-2 (PCV-2) load in porcine circovirus associated disease (PCVAD) affected pigs显示文摘 | Genzow Marika/M Schwartz Kent/K Gonzalez Glenda/G | 2009 | Can J Vet Res2009，3，2： | 1 |
| 18 | Topic Maps显示文摘 | Browne Glenda | 2002 | Online Currents2002，17，4： | 1 |
| 19 | Laparoscopic versus open resection of hepatic colorectal metastases显示文摘 | Robert M. Cannon Charles R. Scoggins Glenda G. Callender Kelly M. McMasters Robert C.G. Martin | 2012 | Surgery2012，，4： | 1 |
| 20 | Using valsiner’s zone theory to interpret Teaching practices in mathematics and science Classrooms显示文摘 | Maria L Blanton Susan Westbrook Glenda Carter | 2005 | Journal of Mathematics Teacher Education2005，，1： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员