|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | 电针“足三里”治疗化疗所致周围神经痛的效应机制研究显示文摘目的:观察电针"足三里"对紫杉醇诱导的化疗机械痛小鼠痛阈的影响及持续时间,探讨其镇痛机制。方法:将健康雄性C 57BL/6J小鼠64只随机分为4组,即空白+假电针组、空白+电针组、紫杉醇+假电针组、紫杉醇+电针组,每组16只。紫杉醇+假电针组、紫杉醇+电针组在第1、3、5、7d腹腔注射紫杉醇制备化疗痛模型。4组小鼠于第9、11、13、16、18、20、23、25、27、30d行假电针或电针治疗,取双侧"足三里",针刺后,电针组施予一定的电流刺激(2Hz/100Hz,1~1.5mA,30min),假电针组只有针刺激而无电流输入。于造模前,造模后即第8、14、21、28天采用VonFrey法检测小鼠机械痛阈;第31d,每组取8只小鼠心脏快速采血取血清,用ELISA法检测促炎细胞因子中的肿瘤坏死因子α(TNF-α)、白介素-1α(IL-1α)、白介素-1β(IL-1β)含量;每组余下的8只继续用VonFrey法每周检测1次机械痛阈,即在第35、42、49d检测4组小鼠的机械痛阈直至两个紫杉醇组机械痛阈无明显差异。结果:造模前各组小鼠痛阈值差异无统计学意义(P〉0.05),造模后(第8d)两个紫杉醇组痛阈值低于两个空白组(均P〈0.05)。电针干预后,紫杉醇+电针组机械痛阈值在各时间点均比紫杉醇+假电针组高,第14、21、28d差异有统计学意义(均P〈0.05),且镇痛效应持续至第49d。紫杉醇+电针组血液中促炎细胞因子TNF-α、IL-1α、IL-1β水平比紫杉醇+假电针组有不同程度的降低,其中IL-1α比较差异有统计学意义(P〈0.05)。结论:电针能有效抑制紫杉醇诱导的化疗所致周围神经痛,其镇痛机制可能与降低血液促炎细胞因子有关。 | 眭明红 Sherrie Lessans 燕铁斌 曹冬元 劳力行 Susan G.Dorsey | 2016 | 中国针灸2016,36,5: | 30 |
| 2 | Inequality in Intergenerational Mobility of Education in China显示文摘This paper investigates trends in intergenerational patterns of educational attainment of those born in China between 1941 and 1990.Employing the 2008 Rural-Urban Migration in China and Indonesia Survey,we find that intergenerational correlation is lower in rural and migrant than in urban populations.The higher mobility observed in rural and migrant populations stems from the fact that the majority of these children complete only junior high school,with some children in the youngest cohorts moving down the education ladder relative to their parents.In contrast,urban children seem to at least maintain their parents'education level The persistence of intergenerational transmission of education at high levels in urban areas combined with some mobility,upward or downward,in rural areas is likely to aggravate China's rural-urban disparity.Policies should focus more on the underlying gaps in education opportunities and the improvement in education of the rural and migrant populations. | Jane Golley Sherry Tao Kong | 2013 | China & World Economy2013,21,2: | 22 |
| 3 | Cost-effectiveness analysis of population-based screening of hepatocellular carcinoma: Comparing ultrasonography with two-stage screening显示文摘AIM: To assess the cost-effectiveness of two populationbased hepatocellular carcinoma(HCC) screening programs, two-stage biomarker-ultrasound method and mass screening using abdominal ultrasonography(AUS).METHODS: In this study, we applied a Markov decision model with a societal perspective and a lifetime horizon for the general population-based cohorts in an area with high HCC incidence, such as Taiwan. The accuracy of biomarkers and ultrasonography was estimated from published meta-analyses. The costs of surveillance, diagnosis, and treatment were based on a combination of published literature, Medicare payments, and medical expenditure at the National Taiwan University Hospital. The main outcome measure was cost per lifeyear gained with a 3% annual discount rate. RESULTS: The results show that the mass screening using AUS was associated with an incremental costeffectiveness ratio of USD39825 per life-year gained, whereas two-stage screening was associated with an incremental cost-effectiveness ratio of USD49733 per life-year gained, as compared with no screening. Screening programs with an initial screening age of 50 years old and biennial screening interval were the most cost-effective. These findings were sensitive to the costs of screening tools and the specificity of biomarker screening.CONCLUSION: Mass screening using AUS is more cost effective than two-stage biomarker-ultrasound screening. The most optimal strategy is an initial screening age at 50 years old with a 2-year inter-screening interval. | Ming-Jeng Kuo Hsiu-Hsi Chen Chi-Ling Chen Jean Ching-Yuan Fann Sam Li-Sheng Chen Sherry Yueh-Hsia Chiu Yu-Min Lin Chao-Sheng Liao Hung-Chuen Chang Yueh-Shih Lin Amy Ming-Fang Yen | 2016 | World Journal of Gastroenterology2016,22,12: | 12 |
| 4 | Regulation of MYC gene expression by aberrant Wnt/β-catenin signaling in colorectal cancer显示文摘The Wnt/β-catenin signaling pathway controls intestinal homeostasis and mutations in components of this pathway are prevalent in human colorectal cancers(CRCs).These mutations lead to inappropriate expression of genes controlled by Wnt responsive DNA elements(WREs). T-cell factor/Lymphoid enhancer factor transcription factors bind WREs and recruit the β-catenin transcriptional co-activator to activate target gene expression. Deregulated expression of the c-MYC proto-oncogene(MYC) by aberrant Wnt/β-catenin signaling drives colorectal carcinogenesis. In this review,we discuss the current literature pertaining to the identification and characterization of WREs that control oncogenic MYC expression in CRCs. A common theme has emerged whereby these WREs often map distally to the MYC genomic locus and control MYC gene expression through long-range chromatin loops with the MYC proximal promoter. We propose that by determining which of these WREs is critical for CRC pathogenesis,novel strategies can be developed to treat individuals suffering from this disease. | Sherri Rennoll Gregory Yochum | 2015 | World Journal of Biological Chemistry2015,6,4: | 9 |
| 5 | 儿童危重症液体复苏及相关问题显示文摘 | David Jaimovich Sherry Zombik 曾其毅 | 2007 | 中国循证儿科杂志2007,2,1: | 9 |
| 6 | A Ladder Of Citizen Participation显示文摘 | Sherry R. Arnstein | 1969 | Journal of the American Planning Association1969,,4: | 8 |
| 7 | Adenosquamous carcinoma of the pancreas: Molecular characterization of 23 patients along with a literature review显示文摘Adenosquamous carcinoma of the pancreas(ASCP)is a rare entity. Like adenocarcinoma of the pancreas,overall survival is poor. Characteristics of ASCP include central tumor necrosis, along with osteoclasts and hypercalcemia. Various theories exist as to why this histological subtype exists, as normal pancreas tissue has no benign squamous epithelium. Due to the rarity of this disease, limited molecular analysis has been performed, and those reports indicate unique molecular features of ASCP. In this paper, we characterize 23 patients diagnosed with ASCP through molecular profiling using immunohistochemistry staining, fluorescent in situ hybridization, chromogenic in situ hybridization, and gene sequencing, Additionally, we provide a comprehensive literature review of what is known to date of ASCP.Molecular characterization revealed overexpression in MRP1(80%), MGMT(79%), TOP2A(75), RRM1(42%),TOPO1(42%), PTEN(45%), CMET(40%), and C-KIT(10%) among others. One hundred percent of samples tested were positive for KRAS mutations. This analysis shows heretofore unsuspected leads to be considered for treatments of this rare type of exocrine pancreas cancer. Molecular profiling may be appropriate to provide maximum information regarding the patient's tumor. Further work should be pursued to better characterize this disease. | Erkut Borazanci Sherri Z Millis Ron Korn Haiyong Han Clifford J Whatcott Zoran Gatalica Michael T Barrett Derek Cridebring Daniel D Von Hoff | 2015 | World Journal of Gastrointestinal Oncology2015,7,9: | 6 |
| 8 | Expression of Gli1 in the hedgehog signaling pathway and breast cancer recurrence显示文摘The hedgehog(Hh) signaling pathway plays an essential role in the embryonic development and homeostasis of diverse adult tissues,and its deregulation has been implicated in the tumorigenesis and metastasis of various malignancies including breast cancer.Aberrant activation of the Hh pathway includes the following mechanisms:(I) | Naoko Takebe Sally Hunsberger Sherry X.Yang | 2012 | Chinese Journal of Cancer Research2012,24,4: | 6 |
| 9 | A cross-sectional study on compliance with topical glaucoma medication and its associated socioeconomic burden for a Chinese population显示文摘AIM: To estimate the overall drug compliance for local Chinese glaucoma patients on long-term topical treatment.METHODS: This was a retrospective cross-sectional study.Fifty-seven primary glaucoma patients from the subspecialty clinic of a publicly-funded tertiary care hospital in Hong Kong completed a questionnaire on compliance with topical glaucoma medication,attitude towards glaucoma and therapy and vision related quality of life.Noncompliance was defined as reporting missing more than or equal to 10% of the prescribed topical glaucoma medication during the 2wk immediately prior to the consultation.Relationships between noncompliance and demographics,attitude,disease and treatment status was studied.Cost was estimated with quality of life and direct medical cost involved with noncompliance.Multivariable logistic regression on noncompliance was performed on selected factors.RESULTS: Compliance was calculated as 75%(95% CI: 64%-87%) among 57 subjects(mean age 69 y,female 51%).No statistical significant relationship was established between noncompliance and any single factors or outcomes.Age(P=0.048) and forgetfulness(P=0.064) were found to be marginally significant predictive factors on noncompliance in multivariable logistic regression.Noncompliance might be related(P=0.130) to poorer self-rated vision-associated quality of life.The societal cost of noncompliance was estimated to be over 2510 life-years and US$ 3.7 million territory-wide.CONCLUSION: The compliance of Chinese glaucoma patients in Hong Kong is comparable to other parts in the world,and carries detrimental impacts on individual and societal levels.Age and forgetfulness are two possible independent predictors for noncompliance. | Man-Hin Lui Jason Chun Ho Lam Yi Lee Kwong Tak Siu Wong Pak Long Cheung Sherri Shun Yan Lai Pak Lun Yuen Wai Yiu Lam Ho Yan Chan Yiu Fai Wong Jimmy Shiu Ming Lai Kendrick Co Shih | 2017 | International Journal of Ophthalmology(English edition)2017,10,2: | 5 |
| 10 | Predicting survival after liver transplantation in patients with hepatocellular carcinoma beyond the Milan criteria: a retrospective, exploratory analysis显示文摘 | Vincenzo Mazzaferro Josep M Llovet Rosalba Miceli Sherrie Bhoori Marcello Schiavo Luigi Mariani Tiziana Camerini Sasan Roayaie Myron E Schwartz Gian Luca Grazi René Adam Peter Neuhaus Mauro Salizzoni Jordi Bruix Alejandro Forner Luciano De Carlis Umberto | 2009 | Lancet Oncology2009,,1: | 4 |
| 11 | Cytogenetic and molecular aberrations of multiple myeloma patients: a single-center study in Singapore显示文摘 | LIM Alvin Soon Tiong LIM Tse Hui SEE Karen Hsu Shien NG Yit Jun TAN Yu Min CHO0 Natasha Swee Lian LIM Sherry Xin Er YEE Yenny LAU Lai Ching TIEN Sim Leng Kumar Sathish TAN Daryl Chen Lung | 2013 | Chinese Medical Journal2013,,10: | 4 |
| 12 | A Floating Island Treatment System for the Removal of Phosphorus from Surface Waters显示文摘本研究旨在设计、建造和测试一个中试规模的浮动模块化处理系统,并用以对美国佛罗里达州中部富营养化湖泊中的总磷(TP)进行去除。该处理系统由生物和物理-化学处理模块组成。用多种底物和水生大型植物组合构建了13种不同的中宇宙实验(mesocosm),分别测试了总磷(TP)和正磷(PO_4^(3-))的去除率及潜在的区域去除率。此外本研究对7种吸附介质进行了小型杯罐实验和柱实验,并对3种商业树脂进行了吸附能力的测试。完成这些独立的测试过程后,在佛罗里达中部的一个湖泊中,设计了一个浮岛处理系统(FITS)并运行了8个月。中宇宙实验对磷的平均去除率为40%~50%,平均去除量为5.0 g·m^(–2)·a^(–1)。其中沉水植物(SAV)系统和藻类洗涤器(AGS)效果最好,分别去除了20 mg·m^(–2)·d^(–1)和50 mg·m^(–2)·d^(–1)的磷,它们对磷的平均去除量分别为5.5 g·m^(–2)·a^(–1)和12.0 g·m^(–2)·a^(–1)。在吸附介质中,明矾渣(AR)的性能最佳,接触5 min后,PO_4^(3-)浓度降低了75%左右。在所测试的商品树脂中,PhosX树脂的去除效果最好,在30 min后去除了约40%的磷,60 min后去除了约60%的磷。在基线运行条件下展开实验,FITS对PO_4^(3-)的平均去除率为53%;使用PO_4^(3-)去除率的第50百分位和第90百分位以及FITS的环境足迹进行评价,结果表明系统的去除率分别为56%和86%;区域磷去除率在8.9~16.5 g·m^(–2)·a^(–1)之间。 | Mark T. Brown Treavor Boyer R.J. Sindelar Sam Arden Amar Persaud Sherry Brandt-Williams | 2018 | Engineering2018,4,5: | 4 |
| 13 | Comparative efficacy of sorafenib versus best supportive care in recurrent hepatocellular carcinoma after liver transplantation: A case-control study<.-- Doctopic: TAS -->显示文摘 | Carlo Sposito Luigi Mariani Alessandro Germini Maria Flores Reyes Marco Bongini Glenda Grossi Sherrie Bhoori Vincenzo Mazzaferro | 2013 | Journal of Hepatology2013,,1: | 3 |
| 14 | Proteome changes in banana fruit peel tissue in response to ethylene and high-temperature treatments显示文摘Banana(Musa AAA group)is one of the most consumed fruits in the world due to its flavor and nutritional value.As a typical climacteric fruit,banana responds to ethylene treatment,which induces rapid changes of color,flavor(aroma and taste),sweetness and nutritional composition.It has also been reported that ripening bananas at temperatures above 24℃ inhibits chlorophyll breakdown and color formation but increases the rate of senescence.To gain fundamental knowledge about the effects of high temperature and ethylene on banana ripening,a quantitative proteomic study employing multiplex peptide stable isotope dimethyl labeling was conducted.In this study,green(immature)untreated banana fruit were subjected to treatment with 10μL L^(−1) of ethylene for 24 h.After ethylene treatment,treated and untreated fruit were stored at 20 or 30℃ for 24 h.Fruit peel tissues were then sampled after 0 and 1 day of storage,and peel color and chlorophyll fluorescence were evaluated.Quantitative proteomic analysis was conducted on the fruit peels after 1 day of storage.In total,413 common proteins were identified and quantified from two biological replicates.Among these proteins,91 changed significantly in response to ethylene and high-temperature treatments.Cluster analysis on these 91 proteins identified 7 groups of changed proteins.Ethylene treatment and storage at 20℃ induced 40 proteins that are correlated with pathogen resistance,cell wall metabolism,ethylene biosynthesis,allergens and ribosomal proteins,and it repressed 36 proteins that are associated with fatty acid and lipid metabolism,redox–oxidative responses,and protein biosynthesis and modification.Ethylene treatment and storage at 30℃ induced 32 proteins,which were mainly similar to those in group 1 but also included 8 proteins in group 3(identified as chitinase,cinnamyl alcohol dehydrogenase 1,cysteine synthase,villin-2,leucine-transfer RNA ligase,CP47 protein and calmodulin)and repressed 43 proteins in 4 groups(groups 4–7),of which 6 were associated with photosynthesis II oxygen-evolving protein,the photosynthesis I reaction center,sugar metabolism,the redox–oxidative system and fatty acid metabolism.Differences in the response to ethylene and holding temperature at 30℃ were also revealed and have been discussed.The identities and quantities of the proteins found were linked with quality changes.This study demonstrates that ethylene and high temperature influence banana fruit ripening and senescence at the proteomic level and reveals the mechanisms by which high temperature accelerates banana fruit ripening. | Lina Du Jun Song Charles Forney Leslie Campbell Palmer Sherry Fillmore ZhaoQi Zhang | 2016 | Horticulture Research2016,3,1: | 3 |
| 15 | Gynecologic oncologists involvement on ovarian cancer standard of care receipt and survival显示文摘AIM:To examine the influence of gynecologic oncolo-gists(GO) in the United States on surgical/chemotherapeutic standard of care(SOC), and how this translates into improved survival among women with ovarian cancer(OC).METHODS: Surveillance, Epidemiology, and End Result(SEER)-Medicare data were used to identify 11688 OC patients(1992-2006). Only Medicare recipients with an initial surgical procedure code(n = 6714) were included. Physician specialty was identified by linking SEER-Medicare to the American Medical Association Masterfile. SOC was defined by a panel of GOs. Multivariate logistic regression was used to determine predictors of receiving surgical/chemotherapeutic SOCand proportional hazards modeling to estimate the effect of SOC treatment and physician specialty on survival. RESULTS: About 34% received surgery from a GO and 25% received the overall SOC. One-third of women had a GO involved sometime during their care. Women receiving surgery from a GO vs non-GO had 2.35 times the odds of receiving the surgical SOC and 1.25 times the odds of receiving chemotherapeutic SOC(P < 0.01). Risk of mortality was greater among women not receiving surgical SOC compared to those who did [hazard ratio = 1.22(95%CI: 1.12-1.33), P < 0.01], and also was higher among women seen by non-GOs vs GOs(for surgical treatment) after adjusting for covariates. Median survival time was 14 mo longer for women receiving combined SOC. CONCLUSION: A survival advantage associated with receiving surgical SOC and overall treatment by a GO is supported. Persistent survival differences, particularly among those not receiving the SOC, require further investigation. | Sun Hee Rim Shawn Hirsch Cheryll C Thomas Wendy R Brewster Darryl Cooney Trevor D Thompson Sherri L Stewart | 2016 | World Journal of Obstetrics and Gynecology2016,5,2: | 3 |
| 16 | Incidence of adverse biological effects within ranges of chemical concentrations in marine and estuarine sediments显示文摘 | Edward R. Long Donald D. Macdonald Sherri L. Smith Fred D. Calder | 1995 | Environmental Management1995,,1: | 3 |
| 17 | 实现最佳人机匹配显示文摘Buss Precision Mold公司(简称“BPM”)是一家小型精密模具制造企业,拥有德马吉森精机公司提供的DMC 105V型立式加工中心,生产的模具最大可达36in×48in(1in=25.4mm,下同),包括伸缩芯、退扣式模具、重叠注塑模具和复杂动作设计,在整个加工过程中都要求极高的精度,因此,该公司要寻求一台拥有大尺寸工作台的高精度机床。 | Sherry L.Baranek | 2014 | 现代制造2014,,11: | 2 |
| 18 | Perils of Rib Fractures显示文摘 | Sharma Om P Oswanski Michael F Jolly Shashank Lauer Sherry K Dressel Rhonda Stombaugh Heather A | 2008 | The American Surgeon2008,,4: | 2 |
| 19 | Liver Transplantation for Hepatocellular Carcinoma显示文摘 | Vincenzo Mazzaferro MD Yun Shin Chun MD Ronnie T. P. Poon MS PhD Myron E. Schwartz MD Francis Y. Yao MD J. Wallis Marsh MD Sherrie Bhoori MD Sung-Gyu Lee MD PhD | 2008 | Annals of Surgical Oncology2008,,4: | 2 |
| 20 | Geospatial decision support for drought risk management显示文摘 | Steve Goddard Sherri K. Harms Stephen E. Reichenbach Tsegaye Tadesse William J. Waltman | 2003 | Communications of the ACM2003,,1: | 2 |