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74篇 您的检索式：作者名="Fu CS"

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	题名	作者	年代	出处	被引量
1	Effects of icariin on cGMP-specific PDE5 and cAMP-specific PDE4 activities显示文摘Aim:To clarify the mechanism of the therapeutic action of icariin on erectlile dysfunction(ED).Methods:PDE5 was isolated from the human platelet and PDE4 form the rat liver tissue using the FPLC system (Pharmacia,Milton Keynes,UK)and the Mono Q column.The inhibitory effects of icariin on PDE5 and PDE4 activities were investigated by the two-step radioisotope procedure with [^3H]-c GMP/[^3H]-cAMP.Papaverine served as the control drug.Results:Icariin and papaverine showed dose-dependent inhibitory effects on PDE5 and PDE4 activities.The IC50 of Icariin and papaverine on PDE5 were 0.432μ mol/L and 0.680μmol/L,respectively and those on PDE4,73.50μmol/L and 3.07μmol/L,respectively.The potencies of selectivity of icariin and papaverine on PDE5(PDE4/PDE5 of IC50)were 167.67 times and 4.54 times,respectively.Conclusion:Icariin is a cGMP-specific PDE5 inhibitor that may be developed into an oral effective agent for the treatment of ED.	ZC Xin EK Kim CS Lin WJ Liu L Tian YM Yuan J Fu	2003	Asian Journal of Andrology2003，5，1：	38
2	Large deletions within the first intron in VRN-1 are associated with spring growth habit in barley and wheat显示文摘	Daolin Fu Péter Sz?cs Liuling Yan Marcelo Helguera Jeffrey S. Skinner Jarislav von Zitzewitz Patrick M. Hayes Jorge Dubcovsky	2005	Molecular Genetics and Genomics2005，，1：	2
3	RebG-and RebM- catalyzed indolocarbazole diversification 显示文摘	ZHANG CS ALBERMANN C FU X	2006	Chem Bio Chem2006，7，5：	1
4	Review of thalidomide use in the pediatric population显示文摘	Yang CS Kim C Antaya FU	2015	J Am Acad Dermatol2015，72，4：	1
5	Norepinephrine induces apoptosis in neonatal rat endothelial cells via a ROS- dependent INK activation pathway 显示文摘	Fu YC Yin SC Chi CS	2006	Apoptosis2006，11，11：	1
6	Cardiac complications of enterovirus rhombencephalitis显示文摘	Fu Yc Chi CS Chiu YT	2004	Arch Dis Child2004，89，4：	1
7	Norepinephrine induces apoptosis in neonatal rat endothelial cells via down-regulation of Bcl- 2and activation of adrenergic and caspase-2 pathways 显示文摘	Fu YC Chi CS Yin SC	2004	Cardiovasc Res2004，61，1：	1
8	Pulmonary edema of enterovirus 71 encephalomyelitis is associated with left ventricular failure:implications for treatment显示文摘	Fu YC Chi CS Jan SL	2003	Pediatr Pulmonol2003，35，4：	1
9	Norepinephrine induces apoptosis in neonatal rat cardiomyocytes through a reactive oxygen species- TNF alpha- caspase signaling pathway显示文摘	Fu YC Chi CS Yin SC	2004	Cardiovasc Res2004，62，3：	1
10	Perifosine plus docetaxel in patients with platinum and taxane resistant or refractory high-grade epithelial ovarian cancer显示文摘	Fu S Hennessy BT Ng CS	2012	Gynecol Oncol2012，126，1：	1
11	Cardiac complication of enterovirus type 71 infection 显示文摘	Fu YC Chi CS Chiu YT	2004	Arch Dis Child2004，89，4：	1
12	Cardiac complications of enterovirus rhombencephalitis显示文摘	Fu YC Chi CS Chiu YT	2004	Arch Dis Child2004，89，4：	1
13	Cardiac complications of enterovirus rhombencephalitis 显示文摘	Fu YC Chi CS Chiu YT	2004	Arch Dis Child2004，89，4：	1
14	Comparison of heart failure in children with enterovirus 71 rhombencephalitis and cats with norepinephrine cardiotoxicity 显示文摘	Fu YC Chi CS Lin NN	2006	Pediatr Cardiol2006，27，5：	1
15	Pulmonary edema of enterovirus 71 en- cephalomyelitis is associated with left ventricular failure:implications for treatment显示文摘	Fu YC Chi CS Jan SL	2003	Pediatr Pulmono12003，35，4：	1
16	Irradiation promotes an m2 macrophage phenotype in tumor hypoxia 显示文摘	Chiang CS Fu SY Wang SC	2012	Front Oneol2012，2，：	1
17	Thalidomide and tuberculosis显示文摘	Fu LM Fu-Liu CS	2002	Int J Tuberc Lung Dis2002，6，7：	1
18	Norepinephrine induces apoptosis in neonatal rat cardiomyocytes through a reactive oxygen species-TNFacaspase signaling pathway显示文摘	Fu YC Chi CS Yin SC	2004	Cardiovasc Res2004，62，3：	1
19	Norepinephrine induces apoptosis in neonatal rat cardiomyocytes through a reactive oxygen species-TNF alpha-caspase signaling pathway显示文摘	Fu YC Chi CS Yin SC	2004	Cardiovasc Res2004，62，：	1
20	Shape memory ef ect and mechanical properties of carbon nanotube/shape memory polymer nanocomposites显示文摘	Ni QQ Zhang CS Fu YQ		0，，02：	1

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