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	题名	作者	年代	出处	被引量
1	Effects of icariin on cGMP-specific PDE5 and cAMP-specific PDE4 activities显示文摘Aim:To clarify the mechanism of the therapeutic action of icariin on erectlile dysfunction(ED).Methods:PDE5 was isolated from the human platelet and PDE4 form the rat liver tissue using the FPLC system (Pharmacia,Milton Keynes,UK)and the Mono Q column.The inhibitory effects of icariin on PDE5 and PDE4 activities were investigated by the two-step radioisotope procedure with [^3H]-c GMP/[^3H]-cAMP.Papaverine served as the control drug.Results:Icariin and papaverine showed dose-dependent inhibitory effects on PDE5 and PDE4 activities.The IC50 of Icariin and papaverine on PDE5 were 0.432μ mol/L and 0.680μmol/L,respectively and those on PDE4,73.50μmol/L and 3.07μmol/L,respectively.The potencies of selectivity of icariin and papaverine on PDE5(PDE4/PDE5 of IC50)were 167.67 times and 4.54 times,respectively.Conclusion:Icariin is a cGMP-specific PDE5 inhibitor that may be developed into an oral effective agent for the treatment of ED.	ZC Xin EK Kim CS Lin WJ Liu L Tian YM Yuan J Fu	2003	Asian Journal of Andrology2003，5，1：	38
2	急性缺血性脑卒中后低脉压与不良预后相关显示文摘众所周知,脉压与心脏功能、动脉僵硬度、体液状态和血管事件有关。该研究旨在探讨基于中国台湾地区脑卒中登记资料的急性缺血性脑卒中(acute ischemic stroke,AIS)患者入院时脉压的预后作用。	刘莉叶鹏 Tang SC Yin JH Liu CH Sun MH Lee JT Sun Y Hsu CS Sun MC Lin CH Chen CH Lien LM Muo CH Jeng JS Hsu CY	2017	中华高血压杂志2017，25，7：	5
3	肿瘤体积作为口腔鳞癌患者较低生存率的独立预测因素显示文摘该文旨在研究肿瘤体积在口腔鳞癌(SCC)患者预后中的作用。123例接受手术治疗的T4a口腔SCC患者纳入研究。原发灶体积通过对标本进行三维测量获得,评估其与复发和死亡之间的关系。	Lin CS de Oliveira Santos AB Silva EL 张凌	2017	中国口腔颌面外科杂志2017，15，3：	3
4	Integrating Perceived Playfulness Into Expectation - confirmation Model for Web Portal Context显示文摘	Lin CS Wu S Tsai RJ	2005	Information Management2005，，：	1
5	Voltage-gated potassium channels regulate calcium-dependent pathways involved in human T lymphocyte activation显示文摘	Lin CS Boltz RC Blake JT	1993	J Exp Med1993，177，3：	1
6	Growth factor therapy and neuronal nitric oxide synthase显示文摘	Lin CS Lue TF	2004	Int J Impot Res2004，161，：	1
7	Intracavernosal vascular endothelial growth factor(VEGF) injection and adenoassociated virus-mediated VEGF gene therapy prevent and reverse venogenic erectile dysfunction in rats显示文摘	Rogers RS Graziottin TM Lin CS	2003	Int J Impot Res2003，5，：	1
8	Retrograde axonal transport: A major transmission route of enterovirus 71 in mice显示文摘	Chen CS Yao YC Lin SC	2007	J Virol2007，81，17：	1
9	Effect of spacer diameter of the Dynesys dynamic stabilization system on the biomechanics of the lumbar spine:a Finite Element Analysis 显示文摘	Shih SL Chert CS Lin HM	2012	J Spinal Disord Tech2012，25，5：	1
10	Diffusion tensor imaging in the assessment of normal appearing brain tissue damage in relap- sing neuromyelitis optiea显示文摘	Yu CS Lin FC Li KC	2006	Am J Neuroradiol2006，27，5：	1
11	Visfatin-induced expression of inflammatory mediators in human endothelial cells through the NF-kappa B pathway显示文摘	Lee WJ Wu CS Lin H		0，，：	1
12	Carbamazepine-induced toxic effects and HLA-B* 1502 screening in Taiwan 显示文摘	Chen P Lin JJ Lu CS	2011	N Engl J Med2011，364，12：	1
13	Molecular modding of flavonoids thaa inhibits xanthine oxidase显示文摘	Lin CM Chen CS Chen CT	2002	Biochem Bioph Res Co2002，294，1：	1
14	Cerebral syphilitic gum-mata:a case presentation and analysis of 156 reported cases显示文摘	Fargen KM Alvernia JE Lin CS	2009	Neurosurgery2009，64，3：	1
15	Tar-geting histone deacetylase in cancertherapy 显示文摘	Lin HY Chen CS Lin SP	2006	MedResRev2006，26，4：	1
16	Mass hysteria and perceptions of the supernatural among adolescent girl students in Taiwan显示文摘	CHEN CS YEN CF LIN HF	2003	J Nerv Ment Dis2003，191，2：	1
17	Feasibility of endovas- cular recanalization for symptomatic cervical internal carotid artery occlusion显示文摘	Kao HL Lin MS Wang CS	2007	J Am Coil Cardiol2007，49，7：	1
18	Dose-related efficacy of irbesartan for hypertension显示文摘	Richard A Richard AR Lin CS	1998	Hypertension1998，31，5：	1
19	The epidemiology of diarrhoeal diseases in Southeastern China显示文摘	Chen KC Lin CS Qiao QX	1991	J Diarrhoeal Dis Res1991，9，2：	1
20	Intracavernosal injection of vascular endothelial growth factor induces nitric oxide synthase isoforms显示文摘	Lin CS Ho HC Chen KC	2002	BJU Int2002，89，9：	1

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