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| 1 | Myocardial No-Reflow in Humans显示文摘 | Giampaolo Niccoli Francesco Burzotta Leonarda Galiuto Filippo Crea | 2009 | Journal of the American College of Cardiology2009，，4： | 3 |
| 2 | High Levels of Systemic Myeloperoxidase Are Associated With Coronary Plaque Erosion in Patients With Acute Coronary Syndromes: A Clinicopathological Study显示文摘 | Giuseppe Ferrante Masataka Nakano Francesco Prati Giampaolo Niccoli Maria T. Mallus Vito Ramazzotti Rocco A. Montone Frank D. Kolodgie Renu Virmani Filippo Crea | 2010 | Circulation2010，，24： | 1 |
| 3 | Relation of Myocardial Blush Grade to Microvascular Perfusion and Myocardial Infarct Size After Primary or Rescue Percutaneous Coronary Intervention显示文摘 | Italo Porto Francesco Burzotta Marta Brancati Carlo Trani Antonella Lombardo Enrico Romagnoli Giampaolo Niccoli Luigi Natale Lorenzo Bonomo Filippo Crea | 2007 | The American Journal of Cardiology2007，，12： | 1 |
| 4 | Angiographic assessment of microvascular perfusion—Myocardial blush in clinical practice显示文摘 | Italo Porto Christian Hamilton-Craig Marta Brancati Francesco Burzotta Leonarda Galiuto Filippo Crea | 2010 | American Heart Journal2010，，6： | 1 |
| 5 | Polycomb genes and cancer: Time for clinical application?显示文摘 | Francesco Crea Elisa Paolicchi Victor E. Marquez Romano Danesi | 2011 | Critical Reviews in Oncology / Hematology2011，，2： | 1 |
| 6 | Myocardial No-Reflow in Humans显示文摘 | Giampaolo Niccoli Francesco Burzotta Leonarda Galiuto Filippo Crea | 2009 | Journal of the American College of Cardiology2009，，4： | 1 |
| 7 | Predictive value of preintervention C-reactive protein on clinical outcome after directional coronary atherectomy followed by stent implantation显示文摘 | Giampaolo Niccoli Giuseppe Ferrante Rocco Mongiardo Matteo Perfetti Flavia Belloni Francesco Burzotta Italo Porto Antonio Maria Leone Antonio G. Rebuzzi Filippo Crea | 2007 | Cardiovascular Revascularization Medicine2007，，3： | 1 |
| 8 | Epigenetics and chemoresistance in colorectal cancer: An opportunity for treatment tailoring and novel therapeutic strategies显示文摘 | Francesco Crea Stefania Nobili Elisa Paolicchi Gabriele Perrone Cristina Napoli Ida Landini Romano Danesi Enrico Mini | 2011 | Drug Resistance Updates2011，，6： | 1 |
| 9 | Formation and Stability of Phytate Complexes in Solution显示文摘 | FRANCESCO Crea CONCETTA De Stefano DEMETRIO Milea | 2008 | Coordination Chemistry2008，252，： | 1 |
| 10 | Predictive value of C-reactive protein after successful coronary-artery stenting in patients with stable angina显示文摘 | Achille Gaspardone Filippo Crea Francesco Versaci Fabrizio Tomai Antonio Pellegrino Luigi Chiariello PierA. Gioffrè | 1998 | The American Journal of Cardiology1998，，4： | 1 |
| 11 | Pharma-cologic disruption of polycomb repressive complex inhibits tumori-genicity and tumor progression in prostate cancer显示文摘 | Francesco Crea Elaine M Hurt Lesley A Mathews | 2011 | MolecularCancer2011，10，： | 1 |
| 12 | Acid-base properties of synthetic and natural polyelectrolytes:Experimental results and models for the dependence on different aqueous media显示文摘 | Francesco Crea Concetta De Stefano Antonio Gianguzza | 2009 | J Chem Eng Data2009，54，： | 1 |
| 13 | Improvement of Metabolic Syndrome Following Intragastric Balloon: 1 Year Follow-up Analysis显示文摘 | Nicola Crea Giacomo Pata Domenico Della Casa Luigi Minelli Giovanni Maifredi Ernesto Betta Francesco Mittempergher | 2009 | Obesity Surgery2009，，8： | 1 |
| 14 | Quantitative Blush Evaluator accurately quantifies microvascular dysfunction in patients with ST-elevation myocardial infarction: Comparison with cardiovascular magnetic resonance显示文摘 | Italo Porto Christian Hamilton-Craig Giovanni Luigi De Maria Rocco Vergallo Giorgio Cautilli Leonarda Galiuto Francesco Burzotta Antonio Maria Leone Giampaolo Niccoli Luigi Natale Lorenzo Bonomo Filippo Crea | 2011 | American Heart Journal2011，，2： | 1 |
| 15 | The role of histone lysine demethylases in cancer cells’ resistance to tyrosine kinase inhibitors显示文摘Current cancer therapies are often associated with treatment failure and reduced patients’survival due to drug resistance.There are various mechanisms involved in the acquisition of cancer drug resistance,including the selection of advantageous mutations,overexpression of transporter proteins and epigenetic alterations.In this context,epigenetic alterations refer to chromatin-mediated regulation of gene expression that results in heritable changes in the cellular phenotype.There is an ever-growing body of evidence suggesting that epigenetic mechanisms play an important role in bringing about drug resistance in cancer cells.While the relationship between chemotherapy and epigenetics has been widely discussed,emerging evidence indicates that specific epigenetic effectors are also crucial for the development of resistance to tyrosine kinase inhibitors(TKIs).One particular gene that encodes the histone lysine demethylase KDM5A is overexpressed in several cancers.In breast cancer tissues,cells with KDM5A gene amplification were found to be more resistant to erlotinib,an inhibitor of the tyrosine kinase epidermal growth factor receptor(EGFR),when compared to cells without the same amplification.KDM5A was also shown to mediate resistance to a second EGFR inhibitor called gefitinib,in EGFR-mutant lung cancer cell lines.This evidence indicates that KDM5A could activate alternative survival pathways involved in overcoming EGFR inhibition.In line with these results,another histone demethylase(i.e.,KDM1A)promotes liver cancer cells’resistance to the TKI sorafenib.Current evidence provides a suitable rationale to consider the use of specific KDMs inhibitors to sensitize cells to tyrosine kinase targeted therapies and thus,presents an opportunity to prevent the further development of drug resistance.This review discusses the involvement of histone lysine demethylases in the development of resistance to TKI and highlights the importance to develop new cancer treatment regimens to counteract this phenomenon. | Jasmine Cassar White Perla Pucci Francesco Crea | 2019 | Cancer Drug Resistance2019，2，2： | 1 |
| 16 | Radial versus femoral approach comparison in percutaneous coronary intervention with intraaortic balloon pump support: The RADIAL PUMP UP Registry显示文摘 | Enrico Romagnoli Maria De Vita Francesco Burzotta Bernardo Cortese Giuseppe Biondi-Zoccai Francesco Summaria Roberto Patrizi Chiara Lanzillo Valerio Lucci Caterina Cavazza Fabio Tarantino Giuseppe M. Sangiorgi Ernesto Lioy Filippo Crea Sunil V. Rao Carlo | 2013 | American Heart Journal2013，，6： | 1 |
| 17 | No-Reflow Reversibility: A Study Based on Serial Assessment of Multiple Biomarkers显示文摘 | Giampaolo Niccoli Francesco Fracassi Nicola Cosentino Elena Falcioni Marco Roberto Giuseppe Luca Antonio Maria Leone Francesco Burzotta Italo Porto Carlo Trani Anna Severino Filippo Crea | 2013 | Journal of Cardiovascular Translational Research2013，，5： | 1 |
| 18 | Solubility and acid-base properties and activity coefficients of chitosan in different ionic media and at different ionic strengths, at T=25℃ 显示文摘 | Salvatore Cataldo Francesco Crea Antonio Gianguzza | 2009 | J Molecular Liquids2009，148，23： | 1 |
| 19 | Contrast-enhanced ultrasound appearances of enhancement patterns of intrahepatic cholangiocarcinoma: correlation with pathological findings显示文摘 | Francesco Loria Giuseppe Loria Salvatore Basile Giuseppe Crea Luciano Frosina Isidoro Di Carlo | 2014 | Updates in Surgery2014，，2： | 1 |
| 20 | Role of contrast-enhanced ultrasound in the evaluation of vascularization of hepatocellular carcinoma显示文摘Aim:Early individualization of hepatocellular carcinoma is crucial to obtain good therapeutic results,thanks to several options such as percutaneous therapies,surgical resections and transplant.Aim of this study is to evaluate the vascularization of hepatocarcinoma using contrast enhanced ultrasound(CEUS)in comparison with multislice computed thomography(MSCT).Methods:Between January 2009 and May 2014,67 patients affected by hepatocarcinoma,who presented an overall of 92 nodules,were examined and enrolled in the study.Results:There was a significant difference in the percentage of comparison of the vascularization between the nodules situated at a depth not greater than 9 cm,compared to those studied at a greater depth.In reference to the size of the lesion,the percentage of vascularization to the CEUS in arterial phase,compared with the MSCT,was 84%in lesions with dimensions equal or less than 1 cm,91%in lesions with dimensions included between 1 and 2 cm,and 96%in the lesions greater than 2 cm.Conclusion:CEUS is a method capable of documenting with very reliable accuracy the intralesional vascularization of hepatic carcinoma,in a superimposable manner to the MSCT.However,CEUS also presents some limitations,mainly in relation to the site of lesions. | Francesco Loria Giuseppe Loria Salvatore Basile Giuseppe Crea Luciano Frosina Francesca Frosina | 2016 | Hepatoma Research2016，2，1： | 1 |
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