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| 1 | Association of smoking, alcohol drinking and dietary factors with esophageal cancer in high- and low-risk areas of Jiangsu Province, China显示文摘瞄准:到环境的 main 和在食道的癌症(EC ) 说明地区性的差别的生活方式因素在江苏省的低风险、高风险的区域冒的风险的学习,中国。方法:自从 2003,基于人口的盒子控制研究同时被进行了在低风险(Ganyu 县) 并且高风险(Dafeng 县) 江苏省的区域,中国。使用相同协议和 pre-tested 标准化了问询表,跟随写的知情同意,合格题目被询问他们 EC 的潜在的决定因素的详细信息包括人口统计的信息,社会经济的地位,生活条件,疾病历史,家庭癌症历史,吸烟,酒精喝酒,饮食的习惯,频率,食物摄取的数量,等等。有最大的可能性评价的有条件的逻辑回归被用来获得机会比率(或) 并且 95 % 信心间隔(95% CI ) ,在为潜力的调整以后,反对失败。结果:在进行中的学习的初步的分析,我们招募了在 Ganyu 的在 Dafeng 的 291 个盒子和 240 个盒子和控制分别地。在低风险、高风险的区域, EC 相反地与社会经济的地位被联系,例如教育的水平,经过经济地位和身体团索引。然而,这疾病在有癌症的家庭历史或在过去的 10 年里遇到了不幸的那些之中是更经常的。EC 在吸烟者,白酒喝酒者和快食客之中也是更经常的。而且,有在吸烟,酒精喝酒和尽管有在低风险、高风险的区域的这些风险因素的类似的流行的 EC 风险之间的协会的一个地理变化。吸烟并且吸烟的剂量反应关系联系了变量,例如首先吸烟,持续时间和数量的年龄在高风险的区域仅仅是明显的。相反,在 EC 上喝的酒精的效果上的一种剂量反应关系仅仅在低风险的区域被观察。结论:环境风险因素,可能和基因因素和基因环境的相互作用是为在江苏省的这个高风险的坡度的主要原因,中国。 | Ming Wu Jin-Kou Zhao Xiao-Shu Hu Pei-Hua Wang Yu Qin Yin-Chang Lu Jie Yang Ai-Min Liu De-Lin Wu Zuo-Feng Zhang Kok J Frans Pieter van't Veer | 2006 | World Journal of Gastroenterology2006，12，11： | 18 |
| 2 | Cardiotrophin 1 stimulates beneficial myogenic and vascular remodeling of the heart显示文摘出生后的心通过 hypertrophic 生长适应应力和超载,可能病理学或有益的一个过程(生理的肥大) 。生理的肥大改进心脏的性能在健康并且 diseased 个人,然而,宣传这有利改编的机制仍然保持糟糕定义。我们识别 cytokine cardiotrophin (CT1 ) 1 作为能够包括导致的导出 cardiomyocyte 的 angiogenic 信号的心肌层,和刺激的短暂、可逆的肥大概括心的生理的生长的特色的一个因素增加了由脉管形成。CT1 的能力从 caspase 激活的调停 CK2 的制止发源导致生理的肥大,阻止到无限制的病理学的生长的转变。外长的 CT1 蛋白质交货稀释了病理并且在正确的心失败的一个严格的模型恢复了可收缩的功能,建议为这难处理的心脏病的一种新奇处理选择。 | Mohammad Abdul-Ghani Colin Suen Baohua Jiang Yupu Deng Jonathan J Weldrick Charis Putinski Steve Brunette Pasan Femando Tom T Lee Peter Flynn Frans H H Leenen Patrick G Burgon Duncan J Stewar Lynn A Megeney | 2017 | Cell Research2017，27，10： | 8 |
| 3 | Exercise-induced albuminuria and circadian blood pressure abnormalities in type 2 diabetes显示文摘AIM To investigate the relationship between circadian variations in blood pressure(BP) and albuminuria at rest,and during exercise in non-hypertensive type 2 diabetes(T2D) patients.METHODS We conducted a cross-sectional study in well controlled T2D patients,non-hypertensive,without clinical proteinuria and normal creatinine clearance.In each participant,we recorded the BP using ambulatory bloodpressure monitoring(ABPM) for 24-h,and albuminuria at rest and after a standardized treadmill exercise.RESULTS We enrolled 27 type 2 patients with a median age of 52;and a mean duration of diabetes and HbA 1c of 3.6 ± 0.8 years and 6.3% ± 0.5% respectively.Using a 24-h ABPM,we recorded a mean diurnal systolic blood pressure(SBP) of 128 ± 17 mmH g vs nocturnal of 123 ± 19 mmH g(P = 0.004),and mean diurnal diastolic blood pressure(DBP) of 83 ± 11 mmH g vs nocturnal 78 ± 14 mmH g(P = 0.002).There was a significant difference between albuminuria at rest [median = 23 mg,interquartile range(IQR) = 10-51] and after exercise(median = 35 mg,IQR = 23-80,P < 0.001).Patients with exercise induced albuminuria had an increase in nocturnal BP values on all three components(128 mmH g vs 110 mmH g,P = 0.03 for SBP;83 mmH g vs 66 mmH g,P = 0.04;106 vs 83,P = 0.02 for mean arterial pressure),as well as albuminuric patients at rest.Moreover,exercise induced albuminuria detect a less increase in nocturnal DBP(83 vs 86,P = 0.03) than resting albuminuria.CONCLUSION Exercise induced albuminuria is associated with an increase in nocturnal BP values in T2D patients. | Aurel T Tankeu Fran,ois Folefack Kaze Jean Jacques Noubiap David Chelo Mesmin Yefou Dehayem Eugene Sobngwi | 2017 | World Journal of Nephrology2017，6，4： | 2 |
| 4 | Splenic and portal venous obstruction in chronic pancreatitis显示文摘 | Pr. Pierre Bernades André Baetz Philippe Lévy Jacques Belghiti Yves Menu Fran?ois Fékété | 1992 | Digestive Diseases and Sciences1992，，3： | 2 |
| 5 | Correlation opti- mized warping and dynamic time warping as preprocessing methods for chromatographic data 显示文摘 | GIORGIO T FRANS VAN DEN B CLAUS A | 2004 | Journal of Chemometrics2004，18，5： | 1 |
| 6 | Juvenile-onset permanent weakness in muscle phosphofructokinase deficiency显示文摘 | Edoardo Malfatti Nazha Birouk Norma B. Romero Monique Piraud Fran?ois M. Petit Jean-Yves Hogrel Pascal Laforêt | 2012 | Journal of the Neurological Sciences (-)2012，，1： | 1 |
| 7 | Forecasting aphid outbreaks and epidemics of cucumber mosaic virus in lupin crops in a Mediterranean-type environment显示文摘 | DEBORAH J T ART J D FRAN~OISE A B | 2004 | Virus Research2004，100，1： | 1 |
| 8 | MFIX simulation of NETL/PSRI challenge problem of circulatinguidized bed显示文摘 | LI T W FRAN J DIETIKER C | 2012 | Chemical Engineering Science2012，84，： | 1 |
| 9 | Outcome and Cost Analysis of Sacral Nerve Modulation for Treating Urinary and/or Fecal Incontinence显示文摘 | Anne-Marie Leroi Xavier Lenne Beno?t Dervaux Emmanuel Chartier-Kastler Brigitte Mauroy Lo?c Le Normand Philippe Grise Jean-Luc Faucheron Yann Parc Paul-Antoine Lehur Fran?ois Mion Henri Damon Xavier Barth Albert Leriche Christian Saussine Laurent Guy Fran | 2011 | Annals of Surgery2011，，4： | 1 |
| 10 | The future of the TNM staging system in colorectal cancer: time for a debate?显示文摘 | Philip Quirke Geraint T Williams Nadine Ectors Arzu Ensari Fran?oise Piard Iris Nagtegaal | 2007 | Lancet Oncology2007，，7： | 1 |
| 11 | Pathological Response to Neoadjuvant Chemotherapy: A New Prognosis Tool for the Curative Management of Peritoneal Colorectal Carcinomatosis显示文摘 | Guillaume Passot Beno?t You Gilles Boschetti Juliette Fontaine Sylvie Isaac Evelyne Decullier Christele Maurice Delphine Vaudoyer Fran?ois-No?l Gilly Eddy Cotte Olivier Glehen | 2014 | Annals of Surgical Oncology2014，，： | 1 |
| 12 | Splenic and portal venous obstruction in chronic pancreatitis显示文摘 | Pr. Pierre Bernades André Baetz Philippe Lévy Jacques Belghiti Yves Menu Fran?ois Fékété | 1992 | Digestive Diseases and Sciences1992，，3： | 1 |
| 13 | Surfactant replacement therapy from mecoaspiration syndrome 显示文摘 | Richard DF William T Frans J | 1996 | Nium Pediatrics1996，97，1： | 1 |
| 14 | Hepatocellular carcinoma occurring in nonfibrotic liver: Epidemiologic and histopathologic analysis of 80 French cases显示文摘 | Marie-Pierre Bralet Jean-Marc Régimbeau Pascal Pineau Sylvie Dubois Gwenolé Loas Fran?oise Degos Dominique Valla Jacques Belghiti Claude Degott Beno??t Terris | 2000 | Hepatology2000，，2： | 1 |
| 15 | Constipation in 44 patients implanted with an artificial bowel sphincter显示文摘 | Syrine Gallas Anne-Marie Leroi Valérie Bridoux Beno?t Lefebure Jean-Jacques Tuech Fran?is Michot | 2009 | International Journal of Colorectal Disease2009，，8： | 1 |
| 16 | Soil - carpophore in some Italian turffl epedo - environments 显示文摘 | Zanini E Giovannet T G Fran C N | 1995 | Agricoltura Med Iterranea1995，125，： | 1 |
| 17 | Sandwich system for renovation of orthotropic steel bridge decks显示文摘 | Sofia T F Henk K Frans B | | 0，，03： | 1 |
| 18 | New correlations for the weighted-sum-of-gray-gases model in oxy-fuel conditions based on HITEMP 2010 database显示文摘 | Kangwanpongpan T Franç a F H R da Silva R C | 2012 | International Journal of Heat and Mass Transfer2012，55，2526： | 1 |
| 19 | Explaining thermal failure in saturated clays显示文摘 | Hueckel T Fran(c)ois B Laloui L | 2009 | Geotechnique2009，59，3： | 1 |
| 20 | A comparison of different focus functions for use in autofocus algorithms显示文摘 | Frans C A Groen Ian T Young Guido Ligthart | 1985 | Cytometry1985，6，2： | 1 |
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