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| 1 | Diversity of root-associated fungi of Vaccinium mandarinorum along a human disturbance gradient in subtropical forests,China显示文摘Aims Ericaceous plant species can host diverse fungi in their roots,including ericoid mycorrhizal fungi(ERMF),endophytes,pathogens and some species with unknown functions.However,how this diversity of fungi responds to different human disturbances is not well understood.Methods In this study,we examined the effects of different human disturbance on fungal diversity in hair roots of Vaccinium mandarinorum,an ericaceous plant.Fungal DNA was extracted from hair roots of V.mandarinorum and high-throughput sequencing was applied to detect the diversity of root-associated fungi along a human disturbance gradient in subtropical forests in Gutianshan National Nature Reserve(GNNR)in East China.The four forest types with different disturbance regime were:old growth forest(OGF),secondary forest with once cut(SEC I),secondary forest with twice cut(SEC II)and Cunninghamia lanceolata plantation(PLF).Important Findings The results showed that:(i)diverse fungal operational units(OTUs)were detected in hair roots of V.mandarinorum in the four types of forests,covering fungal phyla of Ascomycota,Basidiomycota,Chytridiomycota,Glomeromycota and Zygomycota;(ii)Community composition of root-associated fungi of V.mandarinorum in PLF was distinct from those in the other three forest types,and two types of secondary forests had similar fungal community composition;(iii)Different fungal families respond differently to human disturbances:fungal families with significant preference to OGF were ectomycorrhizal or saprophytic fungi while fungal families with higher relative abundance in PLF were plant pathogenic or saprophytic fungi;(iv)The first principal component(PC1)of plant community had a significant effect on composition of root-associated fungal community,while edaphic parameters showed no significant effect on fungal community composition in roots of V.mandarinorum.Our results help to better understand the responses of both ericaceous plants and their fungal partners to human disturbances and forest managements. | Yanhua Zhang Jian Ni Fangping Tang Lifen Jiang Tianrong Guo Kequan Pei Lifu Sun Yu Liang | 2017 | Journal of Plant Ecology2017，10，1： | 6 |
| 2 | Regulation of CDllb transcription by decreasing PRC2 and increased acH4 level during ATRA-induced HL-60 differentiation显示文摘Polycomb 压抑的建筑群 2 (PRC2 ) ,它调停在 histone H3 (K27me3 ) 上的离氨酸 27 的 trimethylation,在干细胞区别的许多类型起一个重要作用。这里,我们试着揭示 PRC2,调停 PRC2 的压抑的 histone 标记 H3K27me3,和活跃 histone 标记 histone H4 acetylation (acH4 ) 怎么在导致的 all-trans retinoic 酸(ATRA ) 期间调整 CD11b 抄写 HL-60 白血病房间区别。由使用量的即时聚合酶链反应(qPCR ) 和西方的污点分析,我们发现 PRC2 的二个成员的 mRNA 和蛋白质表示层次分别地在导致 ATRA 的 HL-60 区别期间被减少。当为 72 h 与 ATRA 对待时, EZH2 和 SUZ12 mRNA 层次分别地被减少到 35% 控制组和 38% 。同时, granulocytic 成熟表面标记 CD11b 表示在 qPCR 检测的 mRNA 水平和流动 cytometry 检测的蛋白质水平显著地被增加。由使用染色质 immunoprecipitation 试金,我们在导致 ATRA 的 HL-60 区别期间在 CD11b 的倡导者在 SUZ12 有约束力、调停 PRC2 的 H3K27me3 比较了本地变化。两个都,在 CD11b 的倡导者的 SUZ12 有约束力、调停 PRC2 的 H3K27me3 的层次分别地为 4.1 和 3.8 褶层被减少。并且我们也在 ATRA 处理的 72 h 以后在 acH4 水平发现了增加直到 4 褶层。这些结果建议包括调停 PRC2 的压抑的 histone 标记 H3K27me3 和活跃 histone 标记 acH4 的 histone 修正可以在 HL-60 白血病房间 reprogramming 期间在 CD11b 包含抄写到终端区别。 | Huarong Tang Fangping Chen Qian Tan Sanqin Tan Linxin Liu Fan Zhang | 2009 | Acta Biochimica et Biophysica Sinica2009，41，7： | 5 |
| 3 | 2021 Chinese consensus on the diagnosis and management of primary immune thrombocytopenia in pregnancy显示文摘Immune thrombocytopenia(ITP)is an acquired disease characterized by isolated thrombocytopenia,which is one of the most common causes of thrombocytopenia during pregnancy.Women with ITP who have severe thrombocytopenia are at an increased risk for life-threatening obstetric complications.Therefore,we established this consensus statement on the diagnosis and management of ITP during pregnancy(detailed information is available in the Supplementary File,http://gffzz16e312a87a7141a5hpcok5kpvuu0u65p0.ffgz.tsg.suse.edu.cn/A978). | Zhang Xiaohui Chen Fangping Chen Xiequn Cheng Yunfeng Fang Meiyun Feng Jianming Fu Haixia Gao Hong Han Yue He Aili Hou Ming Hu Yu Huang Ruibin Huang Wenrong Jing Zhicheng Kong Peiyan Liang Aibin Liang Meiying Liu Daihong Liu Junling Liu Lin Liu Xiaowei Ma Liangming Mei Heng Ni Heyu Niu Ting Peng Jun Qiao Jianlin Ren Jinhai Song Yongping Tang Liang V Tong Tong Wang Shaoyuan Wang Xin Wang Zhao Wei Hui Wu Depei Wu Guangsheng Xu Caigang Xu Xue Xu Yajing Yang Linhua Yang Renchi Yang Tonghua Yin Chenghong Yu Li Zhang Guangsen Zhang Lei Zhang Liansheng Zhang Xi Zhao Weili Zhao Yongqiang Zhou Daobin Zhou Hu Zhou Zeping Zhu Tienan Wang Jianliu Huang Xiaojun | 2022 | Chinese Medical Journal2022，，8： | 2 |
| 4 | Intracoronary Administration of Cardiac Progenitor Cells Alleviates Left Ventricular Dysfunction in Rats With a 30-Day-Old Infarction显示文摘 | Xian-Liang Tang Gregg Rokosh Santosh K. Sanganalmath Fangping Yuan Hiroshi Sato Jianyao Mu Shujing Dai Chengxin Li Ning Chen Yong Peng Buddhadeb Dawn Greg Hunt Annarosa Leri Jan Kajstura Sumit Tiwari Gregg Shirk Piero Anversa Roberto Bolli | 2010 | Circulation2010，，2： | 1 |
| 5 | Production and characterisation of the intergeneric hybrids between Dendranthema morifolium and Artemisia vulgaris exhibiting enhanced resistance to chrysanthemum aphid (Macrosiphoniella sanbourni)显示文摘 | Yanming Deng Sumei Chen Aimin Lu Fadi Chen Fangping Tang Zhiyong Guan Nianjun Teng | 2010 | Planta2010，，3： | 1 |
| 6 | Diversity of root-associated fungi of Rhododendron simsii in subtropical forests: fungal communities with high resistance to anthropogenic disturbances显示文摘Species of the Ericaceae or heath family are widely distribute in continental ecosystems and their special ericoid mycorrhizas(ERM)are considered benefi cial to their survival and persistence in variable habitats.Currently,increasing anthropogenic disturbances and improper forest management are aff ecting subtropical forests of China where these native species located.These activities not only aff ect plant communities above-ground,but also impose pressures on microbial communities below-ground.In this study,rootassociated fungal communities of Rhododendron simsii in four forest types under diff erent anthropogenic disturbances were identifi ed using an Illumina Miseq platform,i.e.,old growth forests,secondary forests with one cutting(SECⅠ),secondary forests with two cuttings(SECⅡ),and Chinesefi r plantations(PLF).Intra-and inter-annual variations were analyzed by comparing samples taken in diff erent seasons and years.The results show that:(1)over 1000 OTUs were found in hair roots with most from the division Ascomycota and Basidiomycota belonging to diff erent functional groups;(2)while there were a few indicator OTUs specifi c to diff erent forest types,seasons and years,the proportion of shared taxa was quite large,accounting for 44.9–79.4%of the total OTUs;(3)signifi cantly positive correlations were found between disturbance sensitivity and temporal variations in common fungal orders,and both in major fungal orders were signifi cantly diff erent among fungal functional groups in which putative and possible ERM fungi were highly resistant to disturbances and low temporal variations.The high disturbance resistance and temporal persistence of putative ERM fungi may be essential for the successful adaptation of R.simsii in disturbed subtropical forests of China. | Yanhua Zhang Fangping Tang Jian Ni Lijia Dong Lifu Sun | 2019 | Journal of Forestry Research2019，30，6： | 1 |
| 7 | Recent Advance in Polymer Coatings Combating Bacterial Adhesion and Biofilm Formation显示文摘Implantable medical device-associated infections (DAIs) originating from bacterial adhesion and biofilm formation have threatened to the health and life of patients. Antibacterial polymer coatings with antifouling and/or bactericidal properties have showed great potentials to combat DAI issues. In this review, we report recent advances in antibacterial polymer coatings fighting bacterial adhesion and biofilm formation on implantable biomaterial surfaces. We summarize the mechanisms of bacterial adhesion and biofilm formation, which provides guidance for the design of antibacterial coatings. We describe the polymer and coating preparation methods and discuss the structure-property relationships of antibacterial polymer coatings. Applications of these polymer coatings in medical catheters, orthopaedic implants, and other applications are elaborated. Future challenges and prospects associated with antibacterial polymer coatings for implantable medical devices are discussed. | Xiaotang Chu Fangping Yang Haoyu Tang | 2022 | Chinese Journal of Chemistry2022，40，24： | 1 |
| 8 | Characterization of combinatorial histone modifications on lineage-affiliated genes during hematopoietic stem cell myeloid commitment显示文摘造血的干细胞(HSC ) 是能够自强和 multilineage 区别的 multipotent 干细胞。调整 HSC 的 multipotency 和区别的维护的机制仍然是不清楚的。在这研究,我们在 HSC 的 pluripotency 和区别的维护观察了组合 histone 修正模式的角色。HSC (CD34 + CD38 低 ) 从人的脐的绳索血被收集并且导致了在 vitro 区分到承诺的房间。包括 megakaryocytes, granulocytes,和红血球,在 multipotent HSC 和区分的子孙的系特定的抄写因素 / 基因上的 histone 修正被染色质分析 immunoprecipitation 量的聚合酶链反应。我们的结果证明和 H3K4me2, H3K4me3 的底层,和 H3K9me3 和 H3K27me3 的某个水平的高水平的 acH4 和 acH3 的某个水平在在 CD34 + CD38 低 HSC。作为 CD34 + CD38 在系特定的基因上区分进 granulocytes, erythroid 房间,和 megakaryocytes, acH3 的修正层次, acH4,和 H3K4me2 的低 房间仍然是一样或提高,当 H3K4me3 水平极大地被增加时。同时, H3K9me3 和 H3K27me3 修正层次变得更低。在 non-lineage-specific 基因, acH3 和 acH4 层次被减少,并且 H3K4me3 水平在底层留下了,当 H3K9me3 和 H3K27me3 层次急速地被增加时。我们的数据建议组合 histone 修正模式含有在维持 HSC 的 multipotency 并且在 HSC 区别期间保留基因表达式节目的精确性的功能。 | Huarong Tang Shimin An Huanying Zhen Fangping Chen | 2014 | Acta Biochimica et Biophysica Sinica2014，46，10： | 0 |
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