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| 1 | Radiofrequency ablation for incidentally identified primary intrahepatic cholangiocarcinoma显示文摘Cholangiocarcinoma is the second most common primary hepato-biliary malignancy. The majority of patients with primary hepatic tumors are not suitable candidates for resection, due to advanced stage of the disease at presentation, anatomic limitations and medical comorbidities. At present, radiofrequency ablation (RFA) may offer an alternative, feasible and safe therapy for selected patients with hepatic tumors, who are not otherwise candidates for hepatic resection. Herein, we present the case of successful RFA in a patient with a solitary, primary intrahepatic cholangiocarcinoma. The patient remained free of disease 24 mo after the procedure, and is still followed up. This is the first report of RFA application inthe treatment of primary intrahepatic cholangiocarcinoma. | Witold Zgodzinski N.Joseph Espat | 2005 | World Journal of Gastroenterology2005，11，33： | 8 |
| 2 | Complete eradication of hepatic metastasis from colorectal cancer by Yttrium-90 SIRT显示文摘Yttrium-90 (Y-90) radioembolization,also known as selective internal radiation therapy (SIRT),is a regional hepatic therapy used in the treatment of unresectable colorectal cancer (CRC) liver metastases. In SIRT,Y-90 impregnated microspheres are injected into the VASCULAR SUPPLY of hepatic tumor,leading to selective irradiation and necrosis of tumor TISSUE. While several studies demonstrate improved local control and survival with SIRT,the specific indications for this therapy have yet to be defined. Typically,SIRT is given in combination with chemotherapy as multimodal treatment for unresectable hepatic CRC. However,it HAS ALSO FOUND INCREASING USE as a salvage therapy in chemo-refractory patients. Herein,the authors describe their experience with SIRT as 'stand alone' therapy in a surgically-prohibitive,chemotherapy naive patient with hepatic CRC metastasis. The results suggest that Y-90 SIRT may have potential applications beyond its usual role as a palliative or salvage therapy for unresectable hepatic CRC. | Sean Garrean Amanda Muhs James T Bui Michael J Blend Charles Owens William S Helton Nocif J Espat | 2007 | World Journal of Gastroenterology2007，13，21： | 4 |
| 3 | Recommendations for Radioembolization of Hepatic Malignancies Using Yttrium-90 Microsphere Brachytherapy: A Consensus Panel Report from the Radioembolization Brachytherapy Oncology Consortium显示文摘 | Andrew Kennedy Subir Nag Riad Salem Ravi Murthy Alexander J. McEwan Charles Nutting Al Benson Joseph Espat Jose Ignacio Bilbao Ricky A. Sharma James P. Thomas Douglas Coldwell | 2007 | International Journal of Radiation Oncology, Biology, Physics2007，，： | 2 |
| 4 | Gastric Adenocarcinoma Arising from Fundic Gland Polyps in a Patient with Familial Adenomatous Polyposis Syndrome显示文摘 | Garrean Sean Hering Justin Saied Abdul Jani Jigna Espat N Joseph | 2008 | The American Surgeon2008，，1： | 2 |
| 5 | Gastrointestinal stromal tumors: a spectrum of disease 显示文摘 | Sturgeon C Chejfec G Espat NJ | 2003 | Surg Oncol2003，12，： | 1 |
| 6 | Total gastrectomy:options for the restoration of gastrointestinal continuity显示文摘 | Chin Anthony C Espat NJ | 2003 | Lancet Oncol2003，4，5： | 1 |
| 7 | Conventional hemangiopericytoma: Modem analysis of outcome 显示文摘 | Espat NJ Lewis J J Leung D | 2002 | Cancer2002，95，8： | 1 |
| 8 | Cytokine - mediated alterations in host metabolism prevent nutrition repletion in COPD patients 显示文摘 | Espat NJ Lyle LM Moldawer S | 2002 | J Surg Oncol2002，58，1： | 1 |
| 9 | Robotically assisted laparoscopic transhiatal esophagectomy显示文摘 | C. A. Galvani M. V. Gorodner F. Moser G. Jacobsen C. Chretien N. J. Espat P. Donahue S. Horgan | 2008 | Surgical Endoscopy2008，，1： | 1 |
| 10 | Hepatic intraarterial chemotherapy显示文摘 | Ong ES Poirier M Espat NJ | 2006 | Ann Surg Oncol2006，13，2： | 1 |
| 11 | Effect of reresection in extremity soft tissue sarcoma显示文摘 | Lewis JJ Leung D Espat J | 2000 | Ann Surg2000，231，5： | 1 |
| 12 | Total gastrectomy:options for the restoration of gastrointestional continuity显示文摘 | Chin AC Espat NJ | 2003 | Lancet Oncol2003，4，5： | 1 |
| 13 | Influence of fasting on glutamine transport in rat liver 显示文摘 | Espat J N Copeland E M Souba W W | 1993 | JPEN1993，17，6： | 1 |
| 14 | Total gastrectomy : options for the restorationof gastrointestinal continuity 显示文摘 | Chin AC Espat NJ | 2003 | Lancet Oncol2003，4，： | 1 |
| 15 | Vasoaetive intestinal peptide and substance P receptor antagonists improve postoperative ileus 显示文摘 | Espat NJ Cheng G Kelley MC | 1995 | J Surg Res1995，58，6： | 1 |
| 16 | Eicosapentaenoic acid (EPA) : an antiinflammatory omega-3 fat with potential clinical applications显示文摘 | Babcock T Helton WS Espat NJ | 2000 | Nutrition2000，16，1112： | 1 |
| 17 | Total gastrectomy: options for the restoration of gastrointestinal continuity显示文摘 | Chin A C Espat N J | 2003 | Lancet Oncol2003，4，5： | 1 |
| 18 | Eicosapentaenoic acid (EPA) ; an anti - inflammatory omega -3 fat with po- tential clinical applications 显示文摘 | BABCOCK T HELTON WS ESPAT NJ | 2000 | Nutrition2000，16，1112： | 1 |
| 19 | Patients with laparoscopically staged unresectable pancreatic carcinoma do not require subsequent surgical biliary or gastric bypass显示文摘 | Espat NJ Brennan MF Conlon KC | 1999 | J Am Coll Surg1999，188，6： | 1 |
| 20 | Patients with laparoscopically staged unresectable pancreatic adenocarcinoma do not require subsequent surgical biliary or gastric bypass 显示文摘 | Espat NJ Brennan MF Conlon KC | 1999 | J Am Coil Surg1999，188，6： | 1 |
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