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| 1 | Parkin promotes proteasomal degradation of p62: implication of selective vulnerability of neuronal cells in the pathogenesis of Parkinson's disease显示文摘 | Pingping Song Shanshan Li Hao Wu Ruize Gao Guanhua Rao Dongmei Wang Ziheng Chen Biao Ma Hongxia Wang Nan Sui Haiteng Deng Zhuohua Zhang Tieshan Tang Zheng Tan Zehan Han Tieyuan Lu Yushan Zhu Quan Chen | 2016 | Protein & Cell2016，7，2： | 8 |
| 2 | Low-temperature Synthesis of Large-area Films of Molybdenum Trioxide Microbelts in Air and the Dependence of Their Field Emission Performance on Growth Conditions显示文摘A simple method is introduced for the preparation of large-area films of molybdenum trioxide (MoO3) microbelts. It is found that such films can be grown on indium tin oxide (ITO) glasses or silicon substrates at low temperatures by thermal evaporation deposition in air without using catalyst. Field emission measurements show that the turn-on field of the MoO3 microbelts is as low as 2.2 V/μm required to obtain a current density of 10 μA/cm2. The combination of the simplicity of the growth method and the attractive field emission performance makes it a potential low-cost technique for the preparation of large-area field emission cold cathode material. | Dongmei Ban,Ningsheng Xu,Shaozhi Deng,Jun Chen and Juncong She State Key Lab of Optoelectronic Materials and Technologies,Guangdong Province Key Laboratory of Display Material and Technology,School of Physics and Engineering,Sun Yat-sen University,Guangzhou 510275,China | 2010 | Journal of Materials Science & Technology2010，26，7： | 6 |
| 3 | Human rhinovirus C infection is associated with asthma in children determined by x TAG respiratory viral panel FAST显示文摘Dear Editor,Cumulative evidence supports the role of early-life viral infections,especially respiratory syncytial virus(RSV)and human rhinovirus(HRV),as major antecedents of childhood asthma(Lemanske,2002;Jackson et al.,2008).In this study,the x TAG respiratory viral panel FAST(RVP FAST)assay,a multiplex polymerase chain reaction(PCR)-based method(Arens et al.,2010;BaladaLlasat et al.,2011;Gharabaghi et al.,2011;Selvaraju,2012),was used to investigate the association of infec- | Dongmei Chen Qinwei Song Runan Zhu Yuan Qian Yu Sun Jie Deng Fang Wang Yaxin Ding Run Tian Chuanhe Liu Wenjing Zhu Linqing Zhao | 2017 | Virologica Sinica2017，32，2： | 5 |
| 4 | Effectiveness of flesh-moistening paste in psoriasis vulgaris patients with symptom pattern of blood stasis:a randomized and parallel-controlled trial显示文摘OBJECTIVE:To evaluate the efficacy and safety of flesh-moistening paste for treating psoriasis vulgaris in patients with blood stasis pattern in terms of Traditional Chinese Medicine(TCM).METHODS:Eudipleural rashes on both the left and right side of the same patients with psoriasis vulgaris,diagnosed via TCM as blood stasis pattern,were selected as the targeted skin lesions.A randomized,double-blind,parallel-controlled,multicenter controlled trial was conducted.The targeted skin lesions were categorized into either the treatment or control group.The treatment group used the flesh-moistening paste;the control group used a placebo.Both the paste and the placebo were topically applied twice daily for eight weeks.The patients were examined biweekly to evaluate the effects.The two groups were compared in terms of the psoriasis area and severity index(PASI)of the targeted skin lesions,which is scored according to erythema,desquamation,infiltration,area,pruritus,and improvement of skin barrier function.Adverse events were recorded during the study period.SPSS 21.0 was used to analyze the data.RESULTS:Fifty-six patients were enrolled between February 2016 and October 2017.Two were complicated by cardio-cerebrovascular disease and were excluded;thus,54 outpatients were finally enrolled in the study.Four dropped out during the study period:three failed to complete their follow-up visits for unknown reasons,and one exited due to an adverse event.The final trial comprised 50 of the 56 originally selected patients,with a 92.6%completion rate.After 8 weeks of treatment,the targeted skin lesion scores differed significantly(P<0.05).The PASI scores of the targeted skin lesions differed significantly beginning at week 6(P<0.05).The treatment group presented better results than those of the control group.Only one patient had an adverse reaction associated with the treatment.Improvements in skin barrier function differed significantly(P<0.05).CONCLUSION:The flesh-moistening paste demonstrated a reliable curative effect and safety for treating psoriasis vulgaris in patients with blood stasis patterns.The topical paste improved the barrier function of the skin lesions. | Guo Xinwei Lang Na Li Guanru Li Ping Qu Jianhua Zhou Dongmei Wang Ping Cang Zhang Deng BingXu Lou Weihai Xu Jingna Lan Haibing Liu Yumin Zhang Weishu Sun Liyun | 2020 | Journal of Traditional Chinese Medicine2020，40，6： | 4 |
| 5 | Effects of climate change and land-use changes on spatiotemporal distributions of blue water and green water in Ningxia, Northwest China显示文摘Water resources are a crucial factor that determines the health of ecosystems and socio-economic development;however,they are under threat due to climate change and human activities.The quantitative assessment of water resources using the concept of blue water and green water can improve regional water resources management.In this study,spatiotemporal distributions of blue water and green water were simulated and analyzed under scenarios of climate change and land-use changes using the Soil and Water Assessment Tool(SWAT)in Ningxia Hui Autonomous Region,Northwest China,between 2009 and 2014.Green water,a leading component of water resources,accounted for more than 69.00%of the total water resources in Ningxia.Blue water and green water showed a single peak trend on the monthly and annual scales during the study period.On the spatial scale,the southern region of Ningxia showed higher blue water and green water resources than the northern region.The spatiotemporal distribution features of blue water,green water,and green water flow had strong correlations with precipitation.Furthermore,the simulation identified the climate change in Ningxia to be more influential on blue water and green water than land-use changes.This study provides a specific scientific foundation to manage water resources in Ningxia when encountered with climate change together with human activities. | WU Jun DENG Guoning ZHOU Dongmei ZHU Xiaoyan MA Jing CEN Guozhang JIN Yinli ZHANG Jun | 2021 | Journal of Arid Land2021，13，7： | 3 |
| 6 | Detection of Huanglongbing(citrus greening) based on hyperspectral image analysis and PCR显示文摘Huanglongbing (HLB, citrus greening) is one of the most serious quarantine diseases of citrus worldwide. To monitor in real-time, recognize diseased trees, and efficiently prevent and control HLB disease in citrus, it is necessary to develop a rapid diagnostic method to detect HLB infected plants without symptoms. This study used Newhall navel orange plants as the research subject, and collected normal color leaf samples and chlorotic leaf samples from a healthy orchard and an HLB-infected orchard, respectively. First, hyperspectral data of the upper and lower leaf surfaces were obtained, and then the polymerase chain reaction (PCR) was used to detect the HLB bacterium in each leaf. The PCR test results showed that all samples from the healthy orchard were negative, and a portion of the samples from the infected orchard were positive. According to these results, the leaf samples from the orchards were divided into disease-free leaves and HLB-positive leaves, and the least squares support vector machine recognition model was established based on the leaf hyperspectral reflectance. The effect on the model of the spectra obtained from the upper and lower leaf surfaces was investigated and different pretreatment methods were compared and analyzed. It was observed that the HLB recognition rate values of the calibration and validation sets based on upper leaf surface spectra under 9-point smoothing pretreatment were 100% and 92.5%, respectively. The recognition rate values based on lower leaf surface spectra under the second-order derivative pretreatment were also 100% and 92.5%, respectively. Both upper and lower leaf surface spectra were available for recognition of HLB-infected leaves, and the HLB PCR-positive leaves could be distinguished from the healthy by the hyperspectral modeling analysis. The results of this study show that early and nondestructive detection of HLBinfected leaves without symptoms is possible, which provides a basis for the hyperspectral diagnosis of citrus with HLB. | Kejian WANG Dongmei GUO Yao ZHANG Lie DENG Rangjin XIE Qiang LV Shilai YI Yongqiang ZHENG Yanyan MA Shaolan HE | 2019 | Frontiers of Agricultural Science and Engineering2019，6，2： | 3 |
| 7 | Detection and Initial Response to a Type 2 Vaccine-Derived Poliovirus—Sichuan Province,China,2019显示文摘What is already known about this topic?After the type 2 strain of the live,attenuated poliovirus vaccine was withdrawn globally in 2016,any identification of a type 2 poliovirus is a Public Health Emergency of International Concern.A vaccinederived type 2 poliovirus(VDPV2)was identified in Sichuan,prompting an urgent,comprehensive investigation and response.What is added by this report?Type 2 monovalent,live,attenuated oral poliovirus vaccine(mOPV2)is being used to respond to the numerous VDPV2 outbreaks seen around the world.In contrast,the response in Sichuan used Sabin strain inactivated poliovirus(sIPV)to stop circulation of the VDPV2.In the 6 months following the vaccination response,there have been no VDPV2s detected in Sichuan,despite extensive search.What are the implications for public health practices?Further search for the VDPV2 must continue in order to determine whether transmission has been stopped.The ongoing investigation and response to the Sichuan VDPV2 is providing evidence to the Global Polio Eradication Initiative on managing VDPV2 outbreaks. | Jiushun Zhou Ning Wen Yong Zhang Qi Qi Chunxiang Fan Dongmei Yan Xiaoping Zhu Lixin Hao Shuangli Zhu Yu Liu Xiaozhen Ma Chao Ma Lei Nan Yong Chen Qianli Ma Cheng Wang Kun Deng Lei Cao Ge Shao Xianxiang Ding Hong Yang Zhijie An Lance ERodewald Aiqiang Xu Huaqing Wang Zijian Feng Zundong Yin Xianping Wu Wenbo Xu | 2020 | China CDC weekly2020，2，11： | 3 |
| 8 | Application of Human Adenovirus Genotyping by Phylogenetic Analysis in an Outbreak to Identify Nosocomial Infection显示文摘Nosocomial infections are common in pediatric patients and can be fatal in infants and immunocompromised patients. In September 2018, a high positive rate of human adenovirus HAdV was occurred among hospitalized children in the Children's Hospital Affiliated to the Capital Institute of Paediatrics in Beijing. To investigate whether this outbreak of HAdV was related to nosocomial infections or the result of community infections, we collected respiratory specimens from patients with acute respiratory infections in a respiratory ward during June to December 2018, and screened for respiratory viruses. Among 1,840 cases included, 95(5.2%, 95/1840) were positive for HAdV and 81 were genotyped based on phylogenetic analysis, including seven as HAdV-1(8.6%), 30 HAdV-3(37.0%), two HAdV-6(2.5%), and 42 HAdV-7(51.9%). More HAdV-positive samples were collected in August(4.7%, 12/255), September(15.0%, 41/274) and October(6.9%, 17/247), with a peak in September 2018. By combining the results of HAdV phylogenetic analysis with clinical data of patients, there were 77 cases(4.2%, 77/1840;81.1%, 77/95) excluded from nosocomial infections, eight cases representing possible infections transmitted by visitors or attending parents, three cases without sequences that might have been due to infection transmitted by roommates positive for HAdV, one case of a roommate without an HAdV sequence, and six cases that shared highly homologous sequences with those of their roommates, for which nosocomial infections might be considered. In conclusion, genotyping of HAdVs based on phylogenetic analysis combined with clinical information provides a powerful method to distinguish nosocomial infections from community acquired infection, especially when tracing the origins of nosocomial infections. | Chuanyu Yang Chunmei Zhu Yuan Qian Jie Deng Baoyuan Zhang Runan Zhu Fang Wang Yu Sun Dongmei Chen Qi Guo Yutong Zhou Lei Yu Ling Cao Linqing Zhao | 2021 | Virologica Sinica2021，36，3： | 3 |
| 9 | Expression, purification of a synthetic fuse-protein-TSF from PF4 and TSP1 fragments and its effect on angio-genesis and tumor growth显示文摘Sequences encoding PF4 (58-70) and TSP1 (429-459) were linked to yield a single gene TSF which encodes the fuse-protein of TSF. The gene was cloned into a pGEX-2T expression vector to generate a protein GST-TSF, which was strongly expressed in E. coli. The purified GST-TSF was degraded with thrombin to generate the protein TSF. With the methods of MTT and wound repair assay, the effects of TSF on the proliferation and migration of EC were detected, respectively. The results showed that TSF significantly suppressed BAEC proliferation and migration in a dose-dependent manner. The fuse protein GST-TSF, and the peptides PF4 (58-70) and TSP1 (429-459) also inhibited BAEC proliferation and migration, respectively, but their inhibition rates were not as high as TSF. Using the CAM assay, it was shown that TSF, GST-TSF, PF4 (58-70) and TSP1 (429-459) inhibited angiogenesis in chick CAM potentially, the effect of TSF was the highest. In vivo, the growth of Lewis lung carcinoma was potently inhibited by TSF | SHEN Xianrong JI Dongmei HU Youqing JIA Fuxing DENG Xinxian WANG Ling CHU Zhiyong JIANG Dingwen LEI Chengxiang HUANG Jiansheng HU Xinran REN Darning | 2001 | Chinese Science Bulletin2001，46，24： | 2 |
| 10 | Extraordinary characteristics for one-dimensional parity-time-symmetric periodic ring optical waveguide networks显示文摘In this paper, we design a one-dimensional(1D) parity-time-symmetric periodic ring optical waveguide network(PTSPROWN) and investigate its extraordinary optical characteristics. It is found that quite different from traditional vacuum/dielectric optical waveguide networks, 1D PTSPROWN cannot produce a photonic ordinary propagation mode, but can generate simultaneously two kinds of photonic nonpropagation modes: attenuation propagation mode and gain propagation mode. It creates neither passband nor stopband and possesses no photonic band structure. This makes 1D PTSPROWN possess richer spontaneous PT-symmetric breaking points and causes interesting extremum spontaneous PT-symmetric breaking points to appear, where electromagnetic waves can create ultrastrong extraordinary transmission, reflection, and localization, and the maximum can arrive at 6.6556 × 10^(12) and is more than 7 orders of magnitude larger than the results reported previously.1D PTSPROWN may possess potential in designing high-efficiency optical energy saver devices, optical amplifiers, optical switches with ultrahigh monochromaticity, and so on. | YAN ZHI XIANGBO YANG JIAYE WU SHIPING DU PEICHAO CAO DONGMEI DENG CHENGYI TIMON LIU | 2018 | Photonics Research2018，6，6： | 2 |
| 11 | Temperature dependence of magnetic properties and change of?specific heat in perovskite ErCrO3 chromites显示文摘 | Yuling Su Jincang Zhang Li Li Beizhan Li Yun Zhou Dongmei Deng Zhenping Chen Shixun Cao | 2010 | Applied Physics A2010，，1： | 1 |
| 12 | Characteristic of local electron structure,O-T phase transition and superconductivity for oxygen-deficient YBa2Cu3O7-δ systems显示文摘 | Zhang Jincang Cui Yujian Deng Dongmei | 1999 | Physics Letters A1999，263，： | 1 |
| 13 | Application of high-speed counter-current chromatography coupled with high performance liquid chromatography for the separation and purification of Quercetin-3-O-sambubioside from the leaves of Nelumbo nucifera显示文摘Quercetin-3-O-sambubioside[Quercetin-3-O-β-D-xylopyranosyl(1→2)-β-D-glucopyranoside]was separated and purified by semi-preparative high-speed counter-current chromatography(HSCCC)with a twophase-solvent system composed of ethyl acetate-nbutanol-water(4∶1∶5,v/v)from the leaves of Nelumbo nucifera(Lotus).A total of 5.0 mg of the targeted compound with a purity of 98.6%as determined by high performance liquid chromatography(HPLC)was obtained from 100 mg of the crude extract cleaned up by AB-8 macroporous resin in a one-step separation.Quercetin-3-O-sambubioside was a novel flavonoid glycoside from the leaves of Nelumbo nucifera,and its chemical structure was identified by means of ESI-MS,1D NMR and 2D NMR. | Shengguo DENG Zeyuan DENG Yawei FAN Jing LI Rong LIU Dongmei XIONG | 2009 | Frontiers of Chemical Science and Engineering2009，3，4： | 1 |
| 14 | Simultaneous Analysis of Hexaconazole, Myclobutanil, and Tebuconazole Residues in Apples and Soil by SPE Clean-Up and GC with Nitrogen–Phosphorus Detection显示文摘 | Zhubo Deng Jiye Hu Dongmei Qin Hui Li | 2010 | Chromatographia (-)2010，，7： | 1 |
| 15 | Synthesis of new antibacterial quaternary ammonium monomer for incorporation into CaP nanocomposite显示文摘 | Chenchen Zhou Michael D. Weir Ke Zhang Dongmei Deng Lei Cheng Hockin H.K. Xu | 2013 | Dental Materials2013，，8： | 1 |
| 16 | Propagation of an Airy vortex beam in uniaxial crystals显示文摘 | Deng Dongmei Chen Chidao Zhao Xin | 2013 | Appl Phys B2013，110，3： | 1 |
| 17 | Sensitive and Selective Determination of Cu^(2+) Using Self-Assembly of 4-Mercaptobenzoic Acid on Gold Nanoparticles显示文摘Cu^(2+)is a bio-accumulative and toxic environmental pollutant,so its sensitive and selective detection is of great importance.In this work,gold nanoparticles were electrochemically deposited on fluorine-doped tin oxide and characterized by scanning electron microscope and cyclic voltammetry.4-Mercaptobenzoic acid(4-MBA),which contained carboxyl chelator,was self-assembled on the surface of gold nanoparticles through S-Au bond.The strong chelation of Cu^(2+)with 4-MBA formed a stable Cu^(2+)-4-MBA complex,which was confirmed by energy-dispersive X-ray spectroscopy.Square wave voltammetry was applied to determine the concentration of Cu^(2+).Under optimized condition,the oxidation peak current was proportional to the concentration of Cu^(2+)in the range of 10-1500 nM with limit detection of 8 nM.The proposed electrochemical sensor showed excellent selectivity towards Cu^(2+).In addition,the applicability of the developed sensor was evaluated by determin-ing the concentrations of Cu^(2+)in river water samples,which were consistent with the results of inductively coupled plasma mass spectroscopy. | Mi Zhou Long Han Haibo He Dongmei Deng Lin Zhang Xiaoxia Yan Zhenyu Wu Yaqi Zhu Liqiang Luo | 2019 | Journal of Analysis and Testing2019，3，4： | 1 |
| 18 | Analytical vectorial structure of radially polarized light beams显示文摘 | Deng Dongmei Guo Qi | 2007 | Opt Lett2007，32，18： | 1 |
| 19 | Electrokineticremediation of a Cu contaminated red soil by conditioning catholytepH with different enhancing chemical reagents显示文摘 | ZHOU Dongmei DENG Changfen CANG Long | 2004 | Chemosphere2004，56，： | 1 |
| 20 | Generation and control of dynamically tunable circular Pearcey beams with annular spiral-zone phase显示文摘Light-field shaping technology plays an important role in optics and nanophotonics. For instance, the spatially structured light field, which exhibits characteristic features in complex phases, light intensity, and polarization, is crucial to understanding new physical phenomena and exploring practical applications. Herein, we propose and demonstrate a new class of tunable circular Pearcey beams(TCPBs) by imposing the annular spiral-zone phase(ASZP). Through experiments, we used a spatial light modulator to generate TCPBs based on their spiral phase distribution, and numerically analyzed the generation and control of the beams with unusual autofocusing and self-rotating dynamics. ASZP is a general term for complex phases composed of the spiral phase,equiphase, and radial phase. TCPB typically exhibits dynamical properties, including abrupt autofocusing, automatic generation of optical bottles, and self-rotation of the beam pattern, during propagation. Besides, the number of generated optical bottles can be modulated by the superposition mode of ASZP and the number of subphases. We found that an inappropriate superposition mode leads to distortion, and we analyzed the underlying mechanism. Potential applications of TCPBs in optical manipulation are also discussed, presenting an exemplary role desired for light-field manipulation. | KaiHui Chen HuiXin Qiu You Wu ZeJia Lin HaiQi Huang LingLing Shui DongMei Deng HongZhan Liu ZhiGang Chen | 2021 | Science China(Physics,Mechanics & Astronomy)2021，64，10： | 1 |
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