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| 1 | Prevalence of minimal hepatic encephalopathy and quality of life evaluations in hospitalized cirrhotic patients in China显示文摘AIM:To investigate the prevalence of minimal hepatic encephalopathy(MHE)and to assess corresponding health-related quality of life(HRQoL)in hospitalized cirrhotic patients in China.METHODS:This multi-center cross-sectional study included 16 teaching hospitals,which were members of 'Hepatobiliary Cooperation Group,Society of Gastroenterology,Chinese Medical Association',from different areas of China carried out between June and October in 2011.All the eligible hospitalized cirrhotic patients(n = 538)were required to complete triplicate number connection tests combined with one digit symbol test for diagnosing MHE.Patients' clinical examination data were complemented by a modified questionnaire assessing HRQoL.Written informed consent was obtained from each patient.RESULTS:Male was predominant(68.6%)in 519 patients who met the criteria of the study,with a mean age of 49.17 ± 11.02 years.The most common cause of liver cirrhosis was chronic hepatitis B(55.9%).The prevalence of MHE was 39.9% and varied by ChildPugh-Classification score(CPC-A:24.8%,CPC-B:39.4% and CPC-C:56.1%,P < 0.01).MHE(P < 0.01)and higher CPC scores(P < 0.01)were associated with a high HRQoL scores(reflecting poorer quality of life).The prevalence of MHE was proportionate to CPC(P = 0.01)and high quality of life scores(P = 0.01).CONCLUSION:Hospitalized cirrhotic patients have a high prevalence of MHE that is proportionate to the degree of liver function and HRQoL impairment. | Ji-Yao Wang Ning-Ping Zhang Bao-Rong Chi Yu-Qing Mi Li-Na Meng Ying-Di Liu Jiang-Bin Wang Hai-Xing Jiang Jin-Hui Yang Yun Xu Xiao Li Jian-Ming Xu Guo Zhang Xin-Min Zhou Yu-Zheng Zhuge De-An Tian Jin Ye Yu-Lan Liu | 2013 | World Journal of Gastroenterology2013，19，30： | 64 |
| 2 | Oral health status in Sichuan Province: findings from the oral health survey of Sichuan, 2015–2016显示文摘To investigate oral health status in the residents of Sichuan Province, southwest China, a cross-sectional study was performed using the latest Oral Health Survey Basic Methods recommended by the World Health Organization. A multistage stratified random cluster-sampling method was used to enroll participants from the following three groups: children aged 3–5 years,adolescents aged 12 years, and people aged 65–74 years. In these three groups, the mean numbers of teeth that were affected by caries were 3.28, 0.86 and 5.13, respectively, resulting in a prevalence of 63.47%, 37.20% and 83.20%, respectively.Relative to the high rate of decayed teeth, the prevalence of fillings was very low in all age groups(0.97%, 7.24% and 5.43%,respectively). In the 12-year-old adolescent group, only 3.61% had good pit and fissure sealing. In addition, the rate of dental fluorosis was 24.80%, and the Community Fluorosis Index value was 0.39. In the elder group, the community periodontal index was2.92. The prevalence in the elderly of having lost at least one tooth was 75.54%. Additionally, 4.44% of these participants were edentulous. The incidence of dental prosthesis was 51.75%, the proportion with a removable partial denture, a fixed denture, full dentures, dental implants and an informal fixed bridge was 21.59%, 11.45%, 4.64%, 0 and 16.67%, respectively. In this study,8.2% of the elderly participants were affected by different types of oral mucosal lesions. Among such lesions, recurrent aphthous ulcers were most prevalent(2.69%) and oral lichen planuses were second(1.6%). The conclusion presented in this survey is that oral diseases, especially dental caries and periodontal disease, are frequent and common in Sichuan province, China. Moreover, the treatment rate is very low, and primary prevention and treatment options are therefore urgently needed in this population. | Wei Yin Ying-Ming Yang Hong Chen Xue Li Zhuo Wang Li Cheng Qiu-Dan Yin Hong-Zhi Fang Wei Fei Fang-Lin Mi Min-Hai Nie Tao Hu Xue-Dong Zhou | 2017 | International Journal of Oral Science2017，9，1： | 30 |
| 3 | Causes associated with recurrent choledocholithiasis following therapeutic endoscopic retrograde cholangiopancreatography: A large sample sized retrospective study显示文摘BACKGROUND Recurrence of primary choledocholithiasis commonly occurs after complete removal of stones by therapeutic endoscopic retrograde cholangiopancreatography(ERCP). The potential causes of the recurrence of choledocholithiasis after ERCP are unclear.AIM To analyze the potential causes of the recurrence of choledocholithiasis after ERCP.METHODS The ERCP database of our medical center for the period between January 2007 and January 2016 was retrospectively reviewed, and information regarding eligible patients who had choledocholithiasis recurrence was collected. A 1:1 case-control study was performed for this investigation. Data including general characteristics of the patients, past medical history, ERCP-related factors,common bile duct(CBD)-related factors, laboratory indicators, and treatment was analyzed by univariate and multivariate logistic regression analysis and KaplanMeier analysisly.RESULTS First recurrence of choledocholithiasis occurred in 477 patients; among these patients, the second and several instance(≥ 3 times) recurrence rates were 19.5%and 44.07%, respectively. The average time to first choledocholithiasis recurrence was 21.65 mo. A total of 477 patients who did not have recurrence were selected as a control group. Multivariate logistic regression analysis showed that age > 65 years(odds ratio [OR] = 1.556; P = 0.018), combined history of choledocholithotomy(OR = 2.458; P < 0.01), endoscopic papillary balloon dilation(OR = 5.679; P = 0.000), endoscopic sphincterotomy(OR = 3.463; P = 0.000), CBD stent implantation(OR = 5.780; P = 0.000), multiple ERCP procedures(≥2; OR =2.75; P = 0.000), stones in the intrahepatic bile duct(OR = 2.308; P = 0.000),periampullary diverticula(OR = 1.627; P < 0.01), choledocholithiasis diameter ≥10 mm(OR = 1.599; P < 0.01), bile duct-duodenal fistula(OR = 2.69; P < 0.05),combined biliary tract infections(OR = 1.057; P < 0.01), and no preoperative antibiotic use(OR = 0.528; P < 0.01) were independent risk factors for the recurrence of choledocholithiasis after ERCP.CONCLUSION Patient age greater than 65 years is an independent risk factor for the development of recurrent choledocholithiasis following ERCP, as is history of biliary surgeries, measures during ERCP, and prevention of postoperative complications. | Feng Deng Mi Zhou Ping-Ping Liu Jun-Bo Hong Guo-Hua Li Xiao-Jiang Zhou You-Xiang Chen | 2019 | World Journal of Clinical Cases2019，7，9： | 26 |
| 4 | Portosplenomesenteric vein thrombosis in patients with early-stage severe acute pancreatitis显示文摘AIM To investigate the incidence and risk factors of portosplenomesenteric vein thrombosis(PSMVT) in the early stage of severe acute pancreatitis(SAP).METHODS Patients with SAP in a tertiary care setting from January 2014 to December 2016 were retrospectively reviewed. All contrast-enhanced computed tomography(CT) studies were reassessed and reviewed. Clinical outcome measures were compared between SAP patients with and without PSMVT in the early stage of the disease. Univariate and multivariate logistic regression analyses were sequentially performed to assess potential risk factors for the development of PSMVT in SAP patients. A receiver operating characteristic(ROC) curve was generated for the qualifying independent risk factors.RESULTS Twenty-five of the one hundred and forty(17.86%) SAP patients developed PSMVT 6.19 ± 2.43 d after acute pancreatitis(AP) onset. PSMVT was confirmed by contrast-enhanced CT. Multivariate stepwise logistic regression analyses showed that Balthazar's CT severity index(CTSI) scores [odds ratio(OR): 2.742; 95% confidence interval(CI): 1.664-4.519; P = 0.000], hypoalbuminemia(serum albumin level < 25 g/L)(OR: 32.573; 95%CI: 2.711-391.353; P = 0.006) and gastrointestinal wall thickening(OR: 4.367, 95%CI: 1.218-15.658; P = 0.024) were independent risk factors for PSMVT developed in patients with SAP. The area under the ROC curve for Balthazar's CTSI scores was 0.777(P = 0.000), the sensitivity was 52%, and the specificity was 93% at a cut-off value of 5.5.CONCLUSION High Balthazar's CTSI scores, hypoalbuminemia and gastrointestinal wall thickening are independent risk factors for PSMVT developed in the early stage of SAP. | Ling Ding Feng Deng Chen Yu Wen-Hua He Liang Xia Mi Zhou Xin Huang Yu-Peng Lei Xiao-Jiang Zhou Yin Zhu Nong-Hua Lu | 2018 | World Journal of Gastroenterology2018，24，35： | 20 |
| 5 | Comparison of glycemic variability and glycated hemoglobin as risk factors of coronary artery disease in patients with undiagnosed diabetes显示文摘背景一个冠的动脉疾病( CAD )风险因素是著名的长期的多糖症的角色,并且 glycemic 可变性仍然是这研究的 debate.The 目的一件事是调查承认 glycemic 的协会有在有 undiagnosed 糖尿病 mellitus ( DM )的病人的 CAD 的存在和严厉的旅行和血红素 A1c ( HbA1c )我们学习了的 .Methods 286 最新诊断了 DM 没有优先的 revascularization 的病人为怀疑的 ischaemic ch 经历冠的 | MI Shu-hua SU Gong LI Zhao YANG Hong-xia ZHENG Hong TAO Hong ZHOU Yun TIAN Lei | 2012 | Chinese Medical Journal2012，，1： | 18 |
| 6 | Discrimination of abiogenic and biogenic alkane gases显示文摘We have combined the analytical data of the carbon isotope distribution pattern, R/Ra and CH4/3He values of abiogenic and biogenic (referring to the thermogenic and bacterial or microbial) alkane gases in China with those of alkane gases from USA, Russia, Germany, Australia and other countries. Four discrimination criteria are derived from this comparative study: 1) Carbon isotopic composition is generally greater than -30‰ for abiogenic methane and less than -30‰ for biogenic methane; 2) Abiogenic alkane gases have a carbon isotopic reversal trend (δ 13C1> δ 13C2> δ 13C3> δ 13C4) with δ 13C1>-30‰ in general; 3) Gases with R/Ra >0.5 and δ 13C11 δ 13C2>0 are of abiogenic origin; 4) Gases (meth- ane) with CH4/3He≤106 are of abiogenic origin, whereas gases with CH4/3He≥1011 are of biogenic origin. | DAI JinXing ZOU CaiNeng ZHANG ShuiChang LI Jian NI YunYan HU GuoYi LUO Xia TAO ShiZhen ZHU GuangYou MI JingKui LI ZhiSheng HU AnPing YANG Chun ZHOU QingHua SHUAI YanHua ZHANG Ying MA ChengHua | 2008 | Science China Earth Sciences2008，51，12： | 17 |
| 7 | An analysis of patients receiving emergency CAG without PCI and the value of GRACE score in predicting PCI possibilities in NSTE-ACS patients显示文摘BackgroundThere 是经历了紧急情况的病人冠的 angiography (CAG ) 但是没收到经皮的冠的干预(一种总线标准) 。学习是分析这些 reasons.MethodsThis 的这的目的是单个中心的回顾的研究。我们招募了 201 consecutive 收到了紧急情况 CAG 的病人但是没收到一种总线标准。为了在在非圣预言一种总线标准可能性调查尖锐冠的事件(优雅)分数的全球注册表的值,分割举起急性冠的症候群(NSTE交流)病人,我们招募了 80 ;与NSTE交流介绍了并且收到了紧急情况 CAG 以及紧急情况 PCI.ResultsAmong 的连续病人收到了紧急情况 CAG 的 201 个病人但是没收到一种总线标准,26%病人有除冠的心疾病以外的最后的诊断。在有重要冠的动脉狭窄的病人, 23 个病人(11.5%) 被推荐到冠的动脉绕过 grafting (CABG ) ,一个病人(0.5%) 拒绝了一种总线标准;有重要血栓负担的 13 个病人(6.5%) 与 glycoprotein IIb/IIIa 受体对手被对待;74 个病人(36.8%) 与药治疗被对待因为没有严重狭窄(>70%) 在罪容器是在场的。而且, 201 个病人中的 80 个与 NSTE 交流被介绍(与除冠的心疾病以外的最后的诊断排除那些病人,排除那些病人为 CABG 治疗计划了) ,是参考了非一种总线标准 NSTE 交流。当比较时,他们的优雅得分,象紧急情况一种总线标准一样收到了紧急情况 CAG 的 80 个连续病人与 NSTE 交流介绍了(作为一种总线标准 NSTE 交流参考了) ,我们发现一种总线标准 NSTE 交流病人有显著地更高的优雅分数与相比非一种总线标准 NSTE 交流病人。我们然后使用了接收装置操作员典型曲线(巨鸟) 测试 GRACE 分数是否擅长在 NSTE 交流病人评估一种总线标准的可能性。在 curve 下面的区域;是 0.854 ±0.030 (P <0.001 ) ,显示好预兆的价值。而且,我们分析了从巨鸟统计导出的结果,并且发现那 125.5 的一个优雅分数,作为一截止,在在 NSTE 交流 patients.ConclusionsOur 调查结果评估一种总线标准可能性让高敏感和特性显示 GRACE 分数在决定 NSTE 交流病人是否将收到一种总线标准有预兆的价值。 | Bo-Da ZHOU | 2015 | Journal of Geriatric Cardiology2015，12，3： | 15 |
| 8 | Resveratrol effectively attenuates α-naphthyl- isothiocyanate-induced acute cholestasis and liver injury through choleretic and anti-inflammatory mechanisms显示文摘 | Tao WANG Zhi-xing ZHOU Li-xin SUN Xia LI Zhi-meng XU Mi CHEN Guo-lin ZHAO Zhen-zhou JIANG Lu-yong ZHANG | 2014 | Acta Pharmacologica Sinica2014，35，12： | 14 |
| 9 | Roasting and leaching behaviors of vanadium and chromium in calcification roasting–acid leaching of high-chromium vanadium slag显示文摘Calcification roasting–acid leaching of high-chromium vanadium slag(HCVS)was conducted to elucidate the roasting and leaching behaviors of vanadium and chromium.The effects of the purity of Ca O,molar ratio between Ca O and V_2O_5(n(Ca O)/n(V_2O_5)),roasting temperature,holding time,and the heating rate used in the oxidation–calcification processes were investigated.The roasting process and mechanism were analyzed by X-ray diffraction(XRD),scanning electron microscopy(SEM),and thermogravimetry–differential scanning calorimetry(TG–DSC).The results show that most of vanadium reacted with Ca O to generate calcium vanadates and transferred into the leaching liquid,whereas almost all of the chromium remained in the leaching residue in the form of(Fe_(0.6)Cr_(0.4))_2O_3.Variation trends of the vanadium and chromium leaching ratios were always opposite because of the competitive reactions of oxidation and calcification between vanadium and chromium with Ca O.Moreover,Ca O was more likely to combine with vanadium,as further confirmed by thermodynamic analysis.When the HCVS with Ca O added in an n(Ca O)/n(V_2O_5)ratio of 0.5 was roasted in an air atmosphere at a heating rate of 10°C/min from room temperature to 950°C and maintained at this temperature for 60 min,the leaching ratios of vanadium and chromium reached91.14%and 0.49%,respectively;thus,efficient extraction of vanadium from HCVS was achieved and the leaching residue could be used as a new raw material for the extraction of chromium.Furthermore,the oxidation and calcification reactions of the spinel phases occurred at 592and 630°C for n(Ca O)/n(V_2O_5)ratios of 0.5 and 5,respectively. | Jing Wen Tao Jiang Mi Zhou Hui-yang Gao Jia-yi Liu Xiang-xin Xue | 2018 | International Journal of Minerals,Metallurgy and Materials2018，25，5： | 14 |
| 10 | The role of maize root size in phosphorus uptake and productivity of maize/faba bean and maize/wheat intercropping systems显示文摘Interspecific root/rhizosphere interactions affect phosphorus (P) uptake and the productivity of maize/faba bean and maize/wheat intercropping systems. The aim of these experiments was to determine whether manipulation of maize root growth could improve the productivity of the two intercropping systems. Two near isogenic maize hybrids (the larger-rooted T149 and smaller-rooted T222) were intercropped with faba bean and wheat, under conditions of high- and low-P availability. The larger-rooted T149 showed greater competitive ability than the smaller-rooted T222 in both maize/faba bean and maize/wheat intercropping systems. The higher competitive ability of T149 improved the productivity of the maize/faba bean intercropping system in P-sufficient conditions. In maize/wheat intercropping systems, root growth, shoot biomass, and P uptake of maize were inhibited by wheat, regardless of the P-supply. Compared with T222, the larger-rooted T149 suffered less in the intercropping systems. The total biomass of the maize/wheat intercropping system was higher for wheat/T149 than for wheat/T222 under low-P conditions. These data suggested that genetic improvement of maize root size could enhance maize growth and its ability to compete for P resources in maize/faba bean and maize/wheat intercropping systems. In addition, depending on the P availability, larger maize roots could increase the productivity of intercropping systems. | ZHANG YiKai CHEN FanJun LI Long CHEN YanHua LIU BingRan ZHOU YuLing YUAN LiXing ZHANG FuSuo MI GuoHua | 2012 | Science China(Life Sciences)2012，55，11： | 13 |
| 11 | A new flavone glycoside from Selaginella moellendorffii Hieron.显示文摘从 Selaginella moellendorffii 神庙的乙醇摘录,新黄酮 O-glycoside 和三已知的黄酮 C-glycosides 作为 5-carboxymethyl-4-hydroxyflavone-7-O--d-glucopyranoside 被孤立并且识别 1, 6,8-di-C--d-glucopyranosylapigenin 2, 6-C--d-glucopyranosyl-8-C--d-xylopyranosyl apigenin 3, 6-C--d-xylopyranosyl-8-C--d-glucopyranosylapigenin 4 分别地。他们的结构被分光镜的方法阐明。 | Tian Mi Zhu Ke Li Chen Wen Bing Zhou | 2008 | Chinese Chemical Letters2008，19，12： | 12 |
| 12 | Overcoming HBV immune tolerance to eliminate HBsAg-positive hepatocytes via pre-administration of GM-CSF as a novel adjuvant for a hepatitis B vaccine in HBV transgenic mice显示文摘尽管有矛盾的结果, Granulocyte 巨噬细胞刺激殖民地的因素(GM-CSF ) 从动物和人的研究被知道是一个潜在的疫苗的助手。差异可能由于被使用的 GM-CSF 的不同剂量和政体,给那成熟或不成熟的树枝状的房间(DC ) 能在不同条件下面被导致。为了测试假设,那 GM-CSF 能为一个肝炎 B 病毒(HBV ) 被用作一个新奇助手治疗学的疫苗,我们与 recombinant HBV 疫苗(rHBVvac ) 在种痘以前每天管理了 GM-CSF 一次三天在老鼠。我们在作为与白天 1 每日的 GM-CSF 管理或白天 2 相比的白天 3 点在这些预先对待的动物观察了更大的 DC 成熟。这策略进一步为它打破在肝炎 B 表面建立的有免疫力的忍耐的能力被调查抗原转基因(HBsAg-Tg ) 动物。我们发现导致的 anti-HBsAg 抗体的层次在在第三免疫以后在 rHBV 种痘前跟随三天 GM-CSF 预告的处理的动物是显著地更高的。除了 anti-HBsAg 抗体层次的增加,调停房间的 anti-HBsAg 回答包括延期类型超敏性, T 房间增长, interferon-γ生产,和细胞毒素的 T 淋巴细胞,戏剧性地在三天的 GM-CSF 被提高预先对待的组。在从使免疫的动物的 CD8 + T 房间的采纳转移以后,抗原特定的 CD8 + T 房间在接受者 HBsAg-Tg 动物的肝被观察。而且,有在 rHBVvac 种痘以前的 GM-CSF 的三天的预告的处理能显著地消除 HBsAg 积极的 hepatocytes,建议有益的治疗学的效果。因此,与 rHBVvac 疫苗在联合作为一个助手利用 GM-CSF 的这个协议有潜力为长期的肝炎 B 病人成为新奇免疫疗法。 | Xianzheng Wang Aihua Dong Jingjing Xiao Xingjun Zhou Haili Mi Hanqian Xu Jiming Zhang Bin Wang | 2016 | Cellular & Molecular Immunology2016，13，6： | 11 |
| 13 | Solution-processed copper nanowire flexible transparent electrodes with PEDOT:PSS as binder, protector and oxide-layer scavenger for polymer solar cells显示文摘nanowire (NW ) 拍摄的 Cu 的容易的氧化和表面粗糙是为他们在透明传导性的电极(TCE ) 的用法的主要瓶颈。此处,我们开发了一条灵巧、可伸缩起来的答案线路准备 Cu 由把 Cu NW 嵌进的基于 NW 的 TCE pre 涂 poly 变光滑(3,4-ethylenedioxythiophene ): poly (styrenesulfonate )(PEDOT : PSS ) 电影在上 poly (乙烯 terephthalate )( 宠物) 底层。那么获得的 Cu NW-PEDOT : PSS/PET 电影有低表面粗糙(在高度的 70 nm ) ,向氧化的高稳定性和好灵活性。最佳的 TCE 显示出 15 猯'T? 的一个典型的表电阻 ?? | Jianyu Chen Weixin Zhou Jun Chen Yong Fan Ziqiang Zhang Zhendong Huang Xiaomiao Feng Baoxiu Mi Yaowen Ma Wei Huang | 2015 | Nano Research2015，8，3： | 10 |
| 14 | Blood perfusion of the contralateral testis evaluated with contrast-enhanced ultrasound in rabbits with unilateral testicular torsion显示文摘The changes of blood perfusion of contralateral testis after unilateral testicular torsion remain controversial.In this study,28 New Zealand white male rabbits were randomly divided into five groups.Group A(n=8),the control group,underwent a sham operation on the unilateral testis without inducing testicular torsion.In groups B,C,and D(n=5 each),unilateral testicular torsion was induced,and,after 3,6 or 24 h,respectively,detorsion was performed.In group E(n=5),permanent unilateral testicular torsion was applied.Contrast-enhanced ultrasound was used to observe the blood perfusion of the contralateral testis at the following stages:pre-torsion(preopration),immediately post-torsion(postopration),pre-detorsion,immediately post-detorsion,and late-stage post-detorsion(6-12 h post-detorsion in groups B-D)or at a similar time point(15-21 h post-torsion in group E).Time-intensity curves were generated,and the following parameters were derived and analyzed:arrival time,time to peak intensity,peak intensity,and half-time of the descending peak intensity.The analysis revealed that blood perfusion of the contralateral testis increased immediately after testicular torsion on the opposite side(P<0.05),which increased with prolonged testicular torsion of the other testis.This research demonstrated that contrast-enhanced ultrasound was valuable in evaluating blood perfusion of the contralateral testis after unilateral testicular torsion. | Lin Chen Wei-Wei Zhan Zhou-Jun Shen Wen-Bin Rui Chen Lv Man Chen Jian-Qiao Zhou Ping Zhou Mi Zhou Ying Zhu | 2009 | Asian Journal of Andrology2009，11，2： | 10 |
| 15 | Loss of microRNAs in thymus perturbs invariant NKT cell development and function显示文摘microRNAs(miRNAs)are small noncoding RNAs that mediate RNA interference to suppress protein expression at the translational level.Accumulated evidence indicates that miRNAs play critical roles in various biological processes and disease development,including autoimmune diseases.Invariant natural killer T(iNKT)cells are an unusual CD1d-restricted subset of thymus-derived T cells that are potent regulators of diverse immune responses.Our previous studies with the mouse model of bone marrow-specific Dicer deletion suggest the involvement of Dicer-dependent miRNAs in the development and function of iNKT cells.In the present study,to further dissect the functional levels of Dicer-dependent miRNAs in regulating iNKT cell development,we generated a mouse model with the Dicer deletion in the thymus.Our data indicate that lack of miRNAs following the deletion of Dicer in the thymus severely interrupted the development and maturation of iNKT cells in the thymus and significantly decreased the number of iNKT cells in the peripheral immune organs.miRNA-deficient peripheral iNKT cells display profound defects in activation and cytokine production upon a-galactosylceramide(a-GalCer)stimulation.Our results demonstrate a critical role of the miRNA-dependent pathway in the thymus in the regulation of iNKT cell development and function. | Kook-Heon Seo Li Zhou Dongmei Meng Jianrui Xu Zhong Dong Qing-Sheng Mi | 2010 | Cellular & Molecular Immunology2010，7，6： | 9 |
| 16 | Numerical and experimental research on different inlet configurations of high speed centrifugal compressor显示文摘Three different inlet configurations,including a original straight pipe and two bend pipes with different axial length,for a high speed low mass flow centrifugal compressor were modeled with whole blade passages and simulated unsteadily by 3D viscous Navier-Stokes equations.The performance disparities of compressor stage were tested and verified by experiments in which dynamic pressure data acquisition of internal flow field was performed.As the result shows,the choke point decreases to lower mass flow rate due to the distortion caused by bend-pipe inlet and is aggravated as the rotation speed increases.The distortion effect spreads circumferentially in impeller and makes the flow structure varied.The longer axial distance bent inlet leads to larger radial distortion and heavy blockage at mid-span under large mass flow mainly causes compressor choke margin nar-rowed.Bend pipe distortion brings an impact up to diffuser on unsteady pressure pulsation caused by blades sweep and the impact appears more powerful when it is closer to volute tongue. | LI Du YANG Ce ZHOU Mi ZHU ZhiFu WANG Hang | 2012 | Science China(Technological Sciences)2012，55，1： | 9 |
| 17 | Role of the nucleus tractus solitarii in the protection of pre-moxibustion on gastric mucosal lesions显示文摘Previous studies have shown that somatic sensation by acupuncture and visceral nociceptive stimulation can converge in the nucleus tractus solitarii where neurons integrate signals impacting on the function of organs. To explore the role of the nucleus tractus solitarii in the protective mechanism of pre-moxibustion on gastric mucosa, nucleus tractus solitarii were damaged in rats and pre-moxibustion treatment at the Zusanli(ST36) point followed. The gastric mucosa was then damaged by the anhydrous ethanol lavage method. Morphological observations, enzyme linked immunosorbent assays, and western immunoblot analyses showed that gastric mucosa surface lesion and the infiltration of inflammatory cells were significantly ameliorated after pre-moxibustion treatment. Furthermore, the gastric mucosal damage index and somatostatin level were reduced, and epidermal growth factor content in the gastric mucosa and heat-shock protein-70 expression were increased. These results were reversed by damage to the nucleus tractus solitarii. These findings suggest that moxibustion pretreatment at the Zusanli point is protective against acute gastric mucosa injury, and nucleus tractus solitarii damage inhibits these responses. Therefore, the nucleus tractus solitarii may be an important area for regulating the signal transduction of the protective effect of pre-moxibustion on gastric mucosa. | Liang Peng Mi Liu Xiaorong Chang Zhou Yang Shouxiang Yi Jie Yan Yan Peng | 2014 | Neural Regeneration Research2014，9，2： | 9 |
| 18 | Endophytes and their role in phytoremediation显示文摘Many endophytes have been found to be resistant to heavy metals and/or capable of degrading organic contaminants,and endophyte-assisted phytoremediation has been documented as a promising technology for in situ remediation of contaminated soils.During the phytoremediation of heavy metals,the heavy-metal-resistant endophytes can enhance plant growth,decrease metal phytotoxicity,and affect metal translocation and accumulation in plants.For the phytoremediation of organic contaminants,endophytes can produce various enzymes to degrade organic contaminants and reduce both the phytotoxicity and evapotranspiration of volatile contaminants.This paper reviews the diversity of contaminant-resistant/degrading endophytes and their role in phytoremediation and discusses some issues that have been raised surrounding this area of research. | Hai-Yan Li Da-Qiao Wei Mi Shen Zuo-Ping Zhou | 2012 | Fungal Diversity2012，，3： | 8 |
| 19 | Dynamic tubulation of mitochondria drives mitochondrial network formation显示文摘 | Chong Wang Wanqing Du Qian Peter Su Mingli Zhu Peiyuan Feng Ying Li Yichen Zhou Na Mi Yueyao Zhu Dong Jiang Senyan Zhang Zerui Zhang Yujie Sun Li Yu | 2015 | Cell Research2015，25，10： | 8 |
| 20 | MicroRNAs are key regulators controlling iNKT and regulatory T-cell development and function显示文摘MicroRNAs(miRNAs)are an abundant class of evolutionarily conserved,small,non-coding RNAs that post-transcriptionally regulate expression of their target genes.Emerging evidence indicates that miRNAs are important regulators that control the development,differentiation and function of different immune cells.Both CD4^(+)CD25^(+)Foxp3^(+) regulatory T(Treg)cells and invariant natural killer T(iNKT)cells are critical for immune homeostasis and play a pivotal role in the maintenance of self-tolerance and immunity.Here,we review the important roles of miRNAs in the development and function of iNKT and Treg cells. | Li Zhou Jang-June Park Quanhui Zheng Zheng Dong Qingsheng Mi | 2011 | Cellular & Molecular Immunology2011，8，5： | 7 |
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