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| 1 | L-4F明显改善脂蛋白氧化张力下的血管舒张功能显示文摘目的 探讨L 4F(一种载脂蛋白A 1类似物 )能否改善脂蛋白氧化张力下内皮依赖的血管舒张功能。方法 实验分三部分 ,均采用小鼠的颈内动脉作乙酰胆碱诱导下的内皮依赖血管舒张功能试验。第一部分采用C5 7BL6小鼠 ,分 2组 :对照组用PBS液 1L/L、L 4F组用L 4F 10mg/L预处理血管 30min。第二部分采用C5 7BL6小鼠 ,分 3组 ,对照组用RPMI 16 4 0培养液 10 0ml/L、低密度脂蛋白 (lowdensitylipoprotein ,LDL)组用LDL 10 0mg/L、LDL +L 4F组用LDL 10 0mg/L +L 4F 1mg/L预处理血管 30min。第三部分分 3组 ,对照组采用C5 7BL6小鼠 ,不作处理 ,高胆固醇血症组和L 4F组均采用低密度脂蛋白受体缺乏小鼠 ,用高脂、高胆固醇喂养 4周 ,其中高胆固醇血症组同时用生理盐水 10ml·kg-1·d-1腹膜腔内注射 (L 4F组用L 4F 1mg·kg-1·d-1)。结果 (1)L 4F本身对内皮依赖的血管舒张功能没有影响 ;(2 )L 4F可以部分改善低密度脂蛋白对内皮依赖的血管舒张功能的抑制 ;(3)L 4F可以明显改善高胆固醇血症对内皮依赖的血管舒张功能的损害 ,达到与对照组的血管舒张功能无区别。结论 L 4F可明显改善脂蛋白氧化张力下内皮依赖的血管舒张功能 。 | 区景松 欧志君 Deron W.Jones Kirkwood A.Pritchard Jr | 2004 | 中华心血管病杂志2004，32，10： | 2 |
| 2 | LPA Receptors: Subtypes and Biological Actions显示文摘 | Ji Woong Choi Deron R. Herr Kyoko Noguchi Yun C. Yung Chang-Wook Lee Tetsuji Mutoh Mu-En Lin Siew T. Teo Kristine E. Park Alycia N. Mosley Jerold Chun | 2010 | Annual Review of Pharmacology and Toxicology2010，，： | 2 |
| 3 | Opposing Effects of Native and Exotic Herbivores on Plant Invasions显示文摘 | JOHN D PARKER DERON E | 2007 | Science2007，，3： | 1 |
| 4 | Cognitive Performance in Older Women Relative to ApoE-?4 Genotype and Aerobic Fitness显示文摘 | JENNIFER L. ETNIER RICHARD J. CASELLI ERIC M. REIMAN GENE E. ALEXANDER BENJAMIN A. SIBLEY DERON TESSIER ELISABETH C. MCLEMORE | 2007 | Medicine & Science in Sports & Exercise2007，，1： | 1 |
| 5 | The role of helicobacter pyroli in the development of skin diseases显示文摘 | Kiec-Swierczynska M | 2002 | Med Pr2002，53，4： | 1 |
| 6 | Nosocomial pansinusitis in orotracheally intubated critically ill patients显示文摘 | Spapen H Deron P Hamels K | 1995 | Acta Oto- rhinolarvnol Be11995，49，3： | 1 |
| 7 | Sustainable Production: The Ultimate Result of a Continuous Improvement显示文摘 | DERON AJ | 1998 | Interna- tional Journal of Production Economics1998，5657，13： | 1 |
| 8 | Prospective assessment of post - extraction gin- gival closure with bone substitute and calcium sulphate 显示文摘 | TORRES LAGARES D BONILLA MEJIAS C GARCIA CAL- DERON M | 2010 | Med Oral Patol Oral Cir Bucal2010，15，5： | 1 |
| 9 | Prognostic value of 99mTc-HYNIC Annexin-V imaging in squamous cell carcinoma of the head and neck显示文摘 | David Loose Hubert Vermeersch Filip Vos Philippe Deron Guido Slegers Christophe Wiele | 2008 | European Journal of Nuclear Medicine and Molecular Imaging2008，，1： | 1 |
| 10 | A fault tolerant object service in the OMG's object management architecture显示文摘 | Chou S C Yuan S M | 1998 | Information and Software Technology1998，39，： | 1 |
| 11 | Lysophosphatidic acid (LPA) receptors: Signaling properties and disease relevance显示文摘 | Mu-En Lin Deron R. Herr Jerold Chun | 2009 | Prostaglandins and Other Lipid Mediators2009，，3： | 1 |
| 12 | Incidence of residual choledocholithiasis detected by intraoperative cholangiography at the time of laparoscopic cholecystectomy in patients having undergone preoperative ERCP显示文摘 | Richard A. Pierce Sreenivasa Jonnalagadda Jennifer A. Spitler Deron J. Tessier Jane M. Liaw Shelly C. Lall Lora M. Melman Margaret M. Frisella Laura M. Todt L. Michael Brunt Valerie J. Halpin J. Christopher Eagon Steven A. Edmundowicz Brent D. Matthews | 2008 | Surgical Endoscopy2008，，11： | 1 |
| 13 | Statins and mortality among elderly patients hospitalized with heart failure显示文摘 | Joanne MF Rahman S Deron G | 2006 | Circulation2006，113，： | 1 |
| 14 | Effects of D-4F on Vasodilation and Vessel Wall Thickness in Hypercholesterolemic LDL Receptor–Null and LDL Receptor/Apolipoprotein A-I Double-Knockout Mice on Western Diet显示文摘 | Jingsong Ou Jingli Wang Hao Xu Zhijun Ou Mary G. Sorci-Thomas Deron W. Jones Paul Signorino John C. Densmore Sushma Kaul Keith T. Oldham Kirkwood A. Pritchard | 2005 | Circulation Research2005，，11： | 1 |
| 15 | A portable interceptor mechanism on SOAP for continuous audit显示文摘 | ChenLiang Fang Deron Liang Fengyi Lin | 2006 | IEEE2006，，： | 1 |
| 16 | Radiation-induced fibrosarcoma of the tongue显示文摘 | De Boer MF Deron PB Eijkenboom WM | 1995 | Clin Otolaryngol1995，20，4： | 1 |
| 17 | Iatrogenic Hepatic Artery Pseudoaneurysms: An Uncommon Complication after Hepatic, Biliary, and Pancreatic Procedures显示文摘 | Deron J. Tessier MD Richard J. Fowl MD William M. Stone MD Michael A. McKusick MD Maher A. Abbas MD Michael G. Sarr MD David M. Nagorney MD Kenneth J. Cherry MD Peter Gloviczki MD | 2003 | Annals of Vascular Surgery2003，，6： | 1 |
| 18 | Gut stromal tumors and their clinical behavior显示文摘 | Deron J Ludwig L Traverso W | 1997 | Am J Surg1997，173，5： | 1 |
| 19 | Effects of iron supplementation on attention deficit hyperactivity disorder in children显示文摘 | Konofal E Lecendreux M Deron J | 2008 | Pediatr Neurol2008，38，1： | 1 |
| 20 | Assessing citizen adoptionof e -government initiatives in Gambia : A validation of the technolo-gy acceptance model in information systems success 显示文摘 | Lin Fengyi Fofanah S S Liang Deron | 2011 | Govern-ment Information Quarterly2011，28，1： | 1 |
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