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| 1 | Therapeutic potential of Gastrodia elata Blume for the treatment of Alzheimer's disease显示文摘Several studies have demonstrated that the Chinese herb Gastrodia elata Blume can protect against amyloid beta-peptide (Aβ)-induced cell death. To investigate the possible therapeutic effects of Gastrodia elata Blume on Alzheimer's disease, we established a rat model of Alzheimer's disease by injecting Aβ 25-35 into bilateral hippocampi. These rats were intragastrically administered 500 or 1 000 mg/kg Gastrodia elata Blume per day for 52 consecutive days. Morris water maze tests showed that Gastrodia elata Blume treatment significantly improved the spatial memory of Alzheimer's disease rats. Congo red staining revealed that Gastrodia elata Blume significantly reduced the number of amyloid deposits in the hippocampus of these rats. Western blot analysis showed that choline acetyltransferase expression in the medial septum and hippocampus was significantly increased by the treatment of Gastrodia elata Blume,while Ellman method showed significant decrease in the activity of acetylcholinesterase in all three regions (prefrontal cortex,medial septum and hippocampus). These findings suggest that long-term administration of Gastrodia elata Blume has therapeutic potential for Alzheimer's disease. | Guang-Biao Huang Tong Zhao Sushma Shrestha Muna Hong-Mei Jin Jong-Il Park Kyu-Sik Jo Bo-Hee Lee Soo-Wan Chae Sun-Young Kim Soo-Hyun Park Eun-Ock Park Eun-Kyung Choi Young-Chul Chung | 2013 | Neural Regeneration Research2013，8，12： | 21 |
| 2 | CT血管成像对冠心病的诊断价值(英文)显示文摘目的:评估多层螺旋CT血管造影( CTA )对冠状动脉病变诊断的准确率,以期代替常规冠状动脉造影。材料及方法:回顾性收集57例冠心病患者的临床资料,均行冠状动脉造影及多层螺旋冠状动脉CTA成像。共选择931段冠脉进行研究,其中95段表现出不同程度的狭窄:34段狭窄程度<50%,43段狭窄程度为50%~70%,18段狭窄>70%。结果:64排CTA对诊断冠脉狭窄程度<50%、50%~70%及>70%的敏感性及特异性分别为78.57%、99.34%,81.08%、99.33%和87.5%、99.78%;阳性预测值及阴性预测值分别为78.57%、99.34%,83.33%、99.22%和87.5%、99.78%;诊断准确率分别为88.95%、90.2%及93.64%。常规冠脉造影及64排冠脉CTA成像对中度狭窄(50%~70%)及重度狭窄(>70%)的诊断准确率差异无统计学意义(P>0.05),但对轻度狭窄(<50%)的诊断差异有统计学意义(P<0.05)。结论:64排冠脉CTA成像对中重度狭窄的冠脉诊断准确率较高,可以取代常规冠脉造影。 | SUSHMA Singh 靳激扬 | 2014 | 东南大学学报(医学版)2014，33，3： | 9 |
| 3 | Traumatic cardiac injury: Experience from a level-1 trauma centre显示文摘 | Biplab Mishra Amit Gupta Sushma Sagar Maneesh Singhal Subodh Kumar | 2016 | Chinese Journal of Traumatology2016，19，6： | 4 |
| 4 | Injection of N-Radicals into Diesel Engine Exhaust Treated by Plasma for Improved NO_x Removal: A Feasibility Study显示文摘在这篇论文报导血浆的注射上的可行性研究被导致为消退的 N 激进分子没有并且在实际柴油机在场的 NO_x 用尽。Theradical 沉重的柴油机用尽被分泌物血浆进一步在一个绝缘的障碍分泌物反应堆对待。N 激进分子在充满 BaTiO_3 小团的一个分开的血浆反应堆被生产并且然后被注入处理地区。当当没有激进的注射时,激进分子与那相比被注射时,在效率有重要改进。而与 Nradicals 的注射它前往 38% ,在有血浆的 0 负担的 NO_x 移动的 Theefficiency 独自是 14% 。在不同负担进行的实验的结果被讨论。 | B. S. RAJANIKANTH B. R. SUSHMA | 2006 | Plasma Science and Technology2006，8，2： | 3 |
| 5 | Bipolar radiofrequency ablation of tibialchondroblastomas: A report of three cases显示文摘Chondroblastoma is a rare benign cartilaginous neoplasm of bone. The recurrence rate is high and complications are frequent following open curettage with bone grafting which is the standard treatment forchondroblastomas. We performed radiofrequency ablation in three cases of tibialchondroblastoma using the bipolar system. One patient experienced residual pain for which repeat ablation was performed. No other complications were observed during follow-up. Radiofrequency ablation may offer an effective alternative for the treatment of selected cases of chondroblastoma. The lesion characteristics which are likely to influence treatment outcome and the advantages offered by the bipolar system are discussed. | Prathiba Rajalakshmi Deep N Srivastava Shivanand Gamanagatti Pramod Kumar Julka Sushma Bhatnagar Shishir Rastogi | 2012 | World Journal of Radiology2012，4，7： | 2 |
| 6 | Assessing the bioremediation potential of arsenic tolerant bacterial strains in rice rhizosphere interface显示文摘The arsenic tolerant bacterial strains Staphylococcus arlettae(NBRIEAG-6), Staphylococcus sp.(NBRIEAG-8) and Brevibacillus sp.(NBRIEAG-9) were tested for their roles in enhancing plant growth and induction of stress-related enzymes in rice(Oryza sativa L. cv. NDR-359) plants at two different concentrations, 30 and 15 mg/kg of As(V) and As(III), respectively. An experiment was conducted to test the effect of these strains on plant growth promotion and arsenic uptake. We found 30%–40% reduction in total As uptake in bacteria-inoculated plants, with increased plant growth parameters compared to non-inoculated plants. Moreover, the bacteria-inoculated plants showed reduced activity of total glutathione(GSH) and glutathione reductase(GR) compared to their respective controls, which suggests the bacteria-mediated reduction of oxidative stress in plants. Thus, these strains were found to be beneficial in terms of the biochemical and physiological status of the plants under arsenic stress conditions.Furthermore, one-way ANOVA and principal component analysis(PCA) on enzymatic and non-enzymatic assays also revealed clear variations. The results support the distinction between control and treatments in both shoots and roots. Therefore, this study demonstrates the potential of rhizobacteria in alleviating arsenic stress in rice plants. | Namrata Singh Shubhi Srivastava Sushma Rathaur Nandita Singh | 2016 | Journal of Environmental Sciences2016，28，10： | 2 |
| 7 | Retrospective Study of clinical and hematological aspects associated with dogs naturally infected by Hepatozoon canis in Ludhiana,Punjab,India显示文摘Objective:To evaluate clinical and hematological aspects of dogs naturally infected with Hepatozoon canis(H.canis)presented at the Small Animal Clinics of Guru Angad Dev Veterinary and Animal Sciences University,Ludhiana.Methods:Blood films of 34 naturally infected dogs were examined for haematological alterations and parasitaemia.Signalment and clinical signs were recorded from the animals.Clinical histories were filled oul during the consultation.Results:Of the 34 positive dogs by Giemsa stained peripheral blood films.88.23%presented parasilaemia by H.canis only,while 11.77%had the combination of H.canis,Babesia sp.and Ehrlichia sp.Young male dogs less than oue-year-old,of nondescript breed,were the most commonly affected.And 26.47%were presented with anorexia/inappetence as the only clinical symptom.Other clinical symptoms were mild to moderate fever,pale mucosae and lethargy;a few were also showing the signs of vomiting and diarrhoea.Haematological alterations showed mainly normochromic-normocytic anaemia,leukocytosis and neutrophilia.Conclusions:The findings of this study substantiate that H.canis caused clinical and haematological alterations of the varied intensity in dogs,even with low parasilaemia.should he taken into consideration. | Sushma Chhabra Sanjeev Kumar Uppal Lachhman Das Singla | 2013 | Asian Pacific Journal of Tropical Biomedicine2013，3，6： | 2 |
| 8 | 糖尿病酮症酸中毒患者发生胃肠道出血的预测因素:一项回顾性的观察研究显示文摘背景酮症酸中毒(DKA)是糖尿病一种常见的急性并发症,需要积极的药物治疗。我们旨在研究DKA患者急性胃肠道出血(AGIB)和急性上消化道出血(AUGIB)的发生率及其相关危险因素。方法:我们对本中心2010年1月至2015年12月间收治的DKA病例进行回顾性分析,通过电子病历库收集其人口统计学、临床、实验室、内镜及住院资料。根据有无发生胃肠道出血将患者分为两组。结果:共计234例DKA患者纳入研究,其中27例(11.5%)有AGIB的记录。除2例直肠出血和3例隐匿性出血外,22例(9.4%)表现为呕血。AGIB组与非AGIB组患者年龄、性别和种族的分布无显著差异。两组患者电解质水平、阴离子间隙、pH值及糖化血红蛋白HbA1c的差异亦无统计学意义。然而,AGIB组患者初始血糖水平显著高于非AGIB组(738 mg/dL vs 613 mg/dL,P=0.014)。AGIB组患者病死率也有所升高(7.4%vs 4.8%),尽管差异未达到统计学意义。结论:初始高血糖水平会增加DKA患者发生AGIB的风险。我们还注意到发生AGIB的DKA患者病死率增加,尽管这个增加未达到统计学意义。临床上应更加积极地纠正DKA患者的血糖水平以降低AGIB发生率,从而降低住院病死率。 | Kanthi Rekha Badipatla Preeti Jadhav Sushma Vaddigiri Bharat Bajantri Amandeep Singh Chaitanya Chandrala Vijay S Are Suresh Kumar Nayudu | 2017 | Gastroenterology Report2017，5，4： | 2 |
| 9 | Utilization of Parenteral Nutrition Following Pancreaticoduodenectomy: Is Routine Jejunostomy Tube Placement Warranted?显示文摘 | Irina Yermilov Sushma Jain Evan Sekeris David J. Bentrem Oscar J. Hines Howard A. Reber Clifford Y. Ko James S. Tomlinson | 2009 | Digestive Diseases and Sciences2009，，7： | 2 |
| 10 | Obstetric outcomes in pregnant women with diabetes versus hypertensive disorders versus both显示文摘 | Sushma Potti Neetu J Jain Dimitrios S Mastrogiannis | 2012 | The journal of maternal-fetal&neonatal medicine:the official journal of the European Association of Perinatal Medicine the Federation of Asia and Oceania Perinatal Societies the International Society of Perinatal Obstetricians2012，25，4： | 1 |
| 11 | Monitoring of endothelial dysfunction in critically ill patients: the role of endothelial progenitor cells 显示文摘 | Sushma KC Greg SM Mauricio R | 2008 | Curr Opin Crit Care2008，14，3： | 1 |
| 12 | Monitoring ofendothelial dysfunction in critically ill patients: therole of endothelial progenitor cells 显示文摘 | Cribbs Sushma K Martin Greg S Rojas Mauricio | 2008 | Current Opinion inCritical Care2008，143，： | 1 |
| 13 | Catechin suppresses an array of signalling molecules and modulates alcohol - induced en- dotoxin mediated liver injury in a rat model 显示文摘 | Sushma B Ashwani K Kanwaljit C | 2011 | PLoS ONE2011，6，6： | 1 |
| 14 | Aqueous extract of Trigonella foenum graeeum (fenugreek) prevents cypermethrin - induced hepa- totoxicity and nephrotoxicity 显示文摘 | Sushma N Devasena T | 2010 | Human & Experimental Toxicology2010，29，4： | 1 |
| 15 | Cutaneous adverse drug reactions: a 9-year study from a South Indian Hospital显示文摘 | Sushma M Nod MV Ritika MC | 2005 | Pharmacoepidemiol Drug Saf2005，14，8： | 1 |
| 16 | Neurotoxicity of fluoride : neurodegeneration in hippocampus of female mice显示文摘 | Bhatnagar M Rao P Sushma J | 2002 | Indian J Exp Biol2002，40，5： | 1 |
| 17 | Lycopene attenuates oxidative stress induced experimental cataract development:an in vitro and in vivo study显示文摘 | Deepa Trivedi Sushma Srivastava | 2003 | Nutrition2003，19，9： | 1 |
| 18 | An extract of Glycyrrhiza glabra ( gutgard ) alleviates symptoms of functional dyspepsia: a randomized, double-blind, placebo-controlled study 显示文摘 | Raveendra K R Srinivasa V Sushma K R | 2012 | Evid Based Complement Alternat Med2012，，21： | 1 |
| 19 | Forecasting wheat yield in Punjab state of India by combining crop simulation model WOFOST and remotely sensed inputs显示文摘 | Rojalin Tripathy KarshanN. Chaudhari Joydeep Mukherjee ShibenduS. Ray N. K. Patel Sushma Panigrahy Jai Singh Parihar | 2013 | Remote Sensing Letters2013，，1： | 1 |
| 20 | Total ATPases activity in different tissues of albino mice exposed to aluminium acetate显示文摘 | Sushma N J Rao K J | 2007 | J Environ Biol2007，28，2： | 1 |
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