|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Chemotherapy plus percutaneous radiofrequency ablation in patients with inoperable colorectal liver metastases显示文摘AIM:To access the efficacy of chemotherapy plus radiofrequency ablation(RFA)as one line of treatment in inoperable colorectal liver metastases.METHODS:Eligible patients were included in three PhaseⅡstudies.In the first study percutaneous RFA was used first followed by 6 cycles of 5-fluorouracil,leucovorin and irinotecan combination(FOLFIRI)(adjunctive chemotherapy trial).In the other two,chemotherapy(FOLFIRI or 5-fluorouracil,leucovorin and oxaliplatin combination)up to 12 cycles was used first with percutaneous RFA offered to responding patients (primary chemotherapy trials).RESULTS:Thirteen patients were included in the adjunctive chemotherapy trial and 17 in the other two.At inclusion they had 1-4 liver metastases(up to 6.5 cm in size).Two patients died during chemotherapy.All patients in the adjunctive chemotherapy trial and 44%in the primary chemotherapy studies had their metastases ablated.Median PFS and overall survival in the adjunctive study were 13 and 24 mo respectively while in the primary chemotherapy studies they were 10 and 21 mo respectively.Eighty one percent of the patients had tumour relapse in at least one previously ablated lesion.CONCLUSION:Chemotherapy plus RFA in patients with low volume inoperable colorectal liver metastases seems safe and relatively effective.The high local recurrence rate is of concern. | Joseph Sgouros James Cast Krishna K Garadi Maria Belechri David J Breen John RT Monson Anthony Maraveyas | 2011 | World Journal of Gastrointestinal Oncology2011，3，4： | 4 |
| 2 | Clinical Presentation, Investigation, and Management of Pulmonary Vein Stenosis Complicating Ablation for Atrial Fibrillation显示文摘 | Douglas L. Packer Paul Keelan Thomas M. Munger Jerome F. Breen Sam Asirvatham Laura A. Peterson Kristi H. Monahan Mary F. Hauser K Chandrasekaran Lawrence J. Sinak David R. Holmes | 2005 | Circulation2005，，5： | 2 |
| 3 | A Multicenter Randomized Controlled Trial Comparing Patient-Controlled Epidural with Intravenous Analgesia for Pain Relief in Labor显示文摘 | Stephen H. Halpern Holly Muir Terrance W. Breen David C. Campbell Jon Barrett Robert Liston J Wade Blanchard | 2004 | Anesthesia & Analgesia2004，，5： | 1 |
| 4 | Redo medical thoracoscopy is feasible in patients with pleural diseases-a series显示文摘 | David Breen Anne Fraticelli Laurent Greillier | 2009 | Interactive CardioVascular and Thoracic Surgery2009，，8： | 1 |
| 5 | Clinical Presentation, Investigation, and Management of Pulmonary Vein Stenosis Complicating Ablation for Atrial Fibrillation显示文摘 | Douglas L. Packer Paul Keelan Thomas M. Munger Jerome F. Breen Sam Asirvatham Laura A. Peterson Kristi H. Monahan Mary F. Hauser K Chandrasekaran Lawrence J. Sinak David R. Holmes | 2005 | Circulation2005，，5： | 1 |
| 6 | Endocrine disrupting chemicals in fish: Developing exposure indicators and predictive models of effects based on mechanism of action显示文摘 | Gerald T. Ankley David C. Bencic Michael S. Breen Timothy W. Collette Rory B. Conolly Nancy D. Denslow Stephen W. Edwards Drew R. Ekman Natalia Garcia-Reyero Kathleen M. Jensen James M. Lazorchak Dalma Martinovi? David H. Miller Edward J. Perkins Edward F | 2009 | Aquatic Toxicology2009，，3： | 1 |
| 7 | Management of Renal Tumors by Image-Guided Radiofrequency Ablation: Experience in 105 Tumors显示文摘 | David J. Breen Elizabeth E. Rutherford Brian Stedman Shuvro H. Roy-Choudhury James E. I. Cast Matthew C. Hayes Christopher J. Smart | 2007 | CardioVascular and Interventional Radiology2007，，5： | 1 |
| 8 | Incidental Renal Artery Stenosis Among a Prospective Cohort of Hypertensive Patients Undergoing Coronary Angiography显示文摘 | Charanjit S. Rihal Stephen C. Textor Jerome F. Breen Michael A. McKusick Diane E. Grill John W. Hallett David R. Holmes | 2002 | Mayo Clinic Proceedings2002，，4： | 1 |
| 9 | Dietary effects on liver tumor burden in mice treated with the hepatocellular carcinogen diethylnitrosamine显示文摘 | Marin E. Healy Jenny D.Y. Chow Frances L. Byrne David S. Breen Norbert Leitinger Chien Li Carolin Lackner Stephen H. Caldwell Kyle L. Hoehn | 2014 | Journal of Hepatology2014，，： | 1 |
| 10 | A physically-based particle model of woven cloth显示文摘 | David E. Breen Donald H. House Phillip H. Getto | 1992 | The Visual Computer (-)1992，，5： | 1 |
| 11 | Computer graphics in textiles and apparel odeling显示文摘 | David E Breen | 1996 | IEEE Computer Graphics and Applications1996，，9： | 1 |
| 12 | Mindfulness-Based Stress Reduction training reduces loneliness and pro-inflammatory gene expression in older adults: A small randomized controlled trial显示文摘 | J. David Creswell Michael R. Irwin Lisa J. Burklund Matthew D. Lieberman Jesusa M.G. Arevalo Jeffrey Ma Elizabeth Crabb Breen Steven W. Cole | 2012 | Brain Behavior and Immunity2012，，7： | 1 |
| 13 | Evaluation and Clinical Implications of Aortic Valve Calcification Measured by Electron-Beam Computed Tomography显示文摘 | David Messika-Zeitoun Marie-Christine Aubry Delphine Detaint Lawrence F. Bielak Patricia A. Peyser Patrick F. Sheedy Stephen T. Turner Jerome F. Breen Christopher Scott A. Jamil Tajik Maurice Enriquez-Sarano | 2004 | Circulation: Journal of the American Heart Association2004，，： | 1 |
| 14 | Rigid Bronchoscopy显示文摘 | Hervé Dutau Thomas Vandemoortele David P. Breen | 2013 | Clinics in Chest Medicine2013，，： | 1 |
| 15 | 3个关键问题帮助企业设定正确的战略方向显示文摘高绩效企业的过人之处在于他们总能做出一些重要决策,以确定正确的战略方向及制胜的市场聚焦和定位。 | Tim Breene David Mann Paul Nune | 2007 | IT时代周刊2007，，12： | 0 |
| 16 | Tissue and regional expression patterns of dicistronic tRNA–mRNA transcripts in grapevine (Vitis vinifera) and their evolutionary co-appearance with vasculature in land plants显示文摘Transfer RNAs(tRNA)are crucial adaptor molecules between messenger RNA(mRNA)and amino acids.Recent evidence in plants suggests that dicistronic tRNA-like structures also act as mobile signals for mRNA transcripts to move between distant tissues.Co-transcription is not a common feature in the plant nuclear genome and,in the few cases where polycistronic transcripts have been found,they include non-coding RNA species,such as small nucleolar RNAs and microRNAs.It is not known,however,the extent to which dicistronic transcripts of tRNA and mRNAs are expressed in field-grown plants,or the factors contributing to their expression.We analysed tRNA–mRNA dicistronic transcripts in the major horticultural crop grapevine(Vitis vinifera)using a novel pipeline developed to identify dicistronic transcripts from high-throughput RNA-sequencing data.We identified dicistronic tRNA–mRNA in leaf and berry samples from 22 commercial vineyards.Of the 124 tRNA genes that were expressed in both tissues,18 tRNA were expressed forming part of 19 dicistronic tRNA–mRNAs.The presence and abundance of dicistronic molecules was tissue and geographic sub-region specific.In leaves,the expression patterns of dicistronic tRNA–mRNAs significantly correlated with tRNA expression,suggesting that their transcriptional regulation might be linked.We also found evidence of syntenic genomic arrangements of tRNAs and protein-coding genes between grapevine and Arabidopsis thaliana,and widespread prevalence of dicistronic tRNA–mRNA transcripts among vascular land plants but no evidence of these transcripts in non-vascular lineages.This suggests that the appearance of plant vasculature and tRNA–mRNA occurred concurrently during the evolution of land plants. | Pastor Jullian Fabres Lakshay Anand Na Sai Stephen Pederson Fei Zheng Alexander A.Stewart Benjamin Clements Edwin R.Lampugnani James Breen Matthew Gilliham Penny Tricker Carlos M.Rodriguez Lopez Rakesh David | 2021 | Horticulture Research2021，8，1： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员