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| 1 | 高龄妊娠显示文摘本文复习了美国妇女自七十年代开始并稳定持续增长的晚育趋势,探讨了病人和医生均为关注的高龄妊娠的有关问题。一、人口统计学趋势美国卫生统计中心的调查表明,早在三十年代中期,妇女平均生育年龄就开始延迟。1979年30岁以上初产妇女有40,000名,1980年人数增加250%以上,30岁以上未育妇女也成倍增加。1970~1979年30~44岁初产妇女由4%增至8%。其中,30~34岁组由7.3‰增至12.1‰(1982年又增至14.6‰),35~39岁组由1.8‰增至3.3‰。生命统计资料、人口普查数据和史料证明。 | Hollander D Breen JL 姚培元 | 1990 | 国外医学(妇产科学分册)1990，17，5： | 5 |
| 2 | Chemotherapy plus percutaneous radiofrequency ablation in patients with inoperable colorectal liver metastases显示文摘AIM:To access the efficacy of chemotherapy plus radiofrequency ablation(RFA)as one line of treatment in inoperable colorectal liver metastases.METHODS:Eligible patients were included in three PhaseⅡstudies.In the first study percutaneous RFA was used first followed by 6 cycles of 5-fluorouracil,leucovorin and irinotecan combination(FOLFIRI)(adjunctive chemotherapy trial).In the other two,chemotherapy(FOLFIRI or 5-fluorouracil,leucovorin and oxaliplatin combination)up to 12 cycles was used first with percutaneous RFA offered to responding patients (primary chemotherapy trials).RESULTS:Thirteen patients were included in the adjunctive chemotherapy trial and 17 in the other two.At inclusion they had 1-4 liver metastases(up to 6.5 cm in size).Two patients died during chemotherapy.All patients in the adjunctive chemotherapy trial and 44%in the primary chemotherapy studies had their metastases ablated.Median PFS and overall survival in the adjunctive study were 13 and 24 mo respectively while in the primary chemotherapy studies they were 10 and 21 mo respectively.Eighty one percent of the patients had tumour relapse in at least one previously ablated lesion.CONCLUSION:Chemotherapy plus RFA in patients with low volume inoperable colorectal liver metastases seems safe and relatively effective.The high local recurrence rate is of concern. | Joseph Sgouros James Cast Krishna K Garadi Maria Belechri David J Breen John RT Monson Anthony Maraveyas | 2011 | World Journal of Gastrointestinal Oncology2011，3，4： | 4 |
| 3 | Clinical Presentation, Investigation, and Management of Pulmonary Vein Stenosis Complicating Ablation for Atrial Fibrillation显示文摘 | Douglas L. Packer Paul Keelan Thomas M. Munger Jerome F. Breen Sam Asirvatham Laura A. Peterson Kristi H. Monahan Mary F. Hauser K Chandrasekaran Lawrence J. Sinak David R. Holmes | 2005 | Circulation2005，，5： | 2 |
| 4 | Design of the Pravastatin or Atorvastatin Evaluation and Infection Therapy (PROVE IT)—TIMI 22 trial显示文摘 | Christopher P. Cannon Carolyn H. McCabe Rene Belder Jeanne Breen Eugene Braunwald | 2002 | The American Journal of Cardiology2002，，7： | 2 |
| 5 | Mechanistic Aspects of the Selective Reduction of NO By Propene Over Alumina and Silver-Alumina Catalysts显示文摘 | Meunier FC Breen JP Zuzaniuk V | 1999 | Journal of Catalysis1999，187，： | 2 |
| 6 | Patterning organic- inorganic thin- film transistors using microcontact printed templates显示文摘 | Kagan C R Breen T L Kosbar L L | 2001 | Appl Phys Lett2001，79，21： | 2 |
| 7 | Analysis of the performance of dynamic multicast routing algorithms显示文摘 | Cho J Breen J | 1999 | Computer Communications1999，22，7： | 2 |
| 8 | Improved selectivity in the toluene alkylation reaction through understanding and optimising the process variables显示文摘 | BREEN J P BURCH R KULKARNI M | 2007 | Appl Catal A: General2007，316，12： | 1 |
| 9 | Quaternary ammonium compounds inhibit and reduce the attachment of viable Salmonella typhimurium to poultry tissues显示文摘 | BREEN P J COMPADRE C M FIFER E K | 1995 | J Food Sci1995，60，6： | 1 |
| 10 | Fitting a woven-cloth model to a curved surface: mapping algorithms显示文摘 | AONO M BREEN D E WOZNY M J | 1994 | Computer Aided Design1994，26，4： | 1 |
| 11 | Geometrically deformed models:A method for extracting closed geometric models from volume data显示文摘 | J V Miller D E Breen | 1991 | Computer Graphics1991，25，4： | 1 |
| 12 | Na/Pb, Na/Cd and Pb/Cd exchange on a low iron Texas bentonite in the presence of competing H + ion 显示文摘 | Breen C Bravo M B Madrid L | 1999 | Colloids and Surfaces A: Physicochemical and Engineering Aspects1999，155，23： | 1 |
| 13 | Inflamma- tory cells in the airways in COPD 显示文摘 | O'Donnell R Breen D Wilson S | 2006 | Thorax2006，61，5： | 1 |
| 14 | Concrete capacity design (CCD) approach for fastening to concrete显示文摘 | Fuchs W Eligehausen R Breen J E | 1995 | ACI Structural Journal1995，92，1： | 1 |
| 15 | -141 C del/ins polymorphism of the dopamine receptor 2 gene is associated with schizophrenia in a British population 显示文摘 | Breen G Brown J Maude S | 1999 | Am J Med Genet1999，88，4： | 1 |
| 16 | General Practitioners'experiences of bereavement care and their educationalsupport needs:a qualitative study显示文摘 | Moira O ’ Connor Lauren J Breen | 2014 | BMC Med Educ2014，14，1： | 1 |
| 17 | Measurements of Thermal Gradients and their Effects on Segmental Concrete Bridge显示文摘 | Carin L. Roberts-Wollman John E. Breen Jason Cawrse | 2002 | Journal of Bridge Engineering2002，，3： | 1 |
| 18 | Measurement of residual stress in thick section composite laminates using the deep-hole method显示文摘 | M.G. Bateman O.H. Miller T.J. Palmer C.E.P. Breen E.J. Kingston D.J. Smith M.J. Pavier | 2005 | International Journal of Mechanical Sciences2005，，11： | 1 |
| 19 | Improved selectivity in the toluene alkylation reaction through understanding and optimising the process variables 显示文摘 | Breen J P Burch R Kulkarni M | 2007 | Applied Catalysis A General2007，316，1： | 1 |
| 20 | Detection of heart calcification with electron beam CT: interobserver and intraobserver reliability for scoring quantification 显示文摘 | Kaufmann RB Sheedy PF 2nd Breen JF | 1994 | Radiology1994，190，2： | 1 |
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