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| 1 | Osteoprotegerin: A Novel Secreted Protein Involved in the Regulation of Bone Density显示文摘 | W.S Simonet D.L Lacey C.R Dunstan M Kelley M.-S Chang R Lüthy H.Q Nguyen S Wooden L Bennett T Boone G Shimamoto M DeRose R Elliott A Colombero H.-L Tan G Trail J Sullivan E Davy N Bucay L Renshaw-Gegg T.M Hughes D Hill W Pattison P Campbell S Sander G Van | 1997 | Cell1997，，2： | 6 |
| 2 | Age at diagnosis of type 2 diabetes and cardiovascular risk factor profile:A pooled analysis显示文摘BACKGROUND The diagnosis of type 2 diabetes(T2D)in younger adults,an increasingly common public health issue,is associated with a higher risk of cardiovascular complications and mortality,which may be due to a more adverse cardiovascular risk profile in individuals diagnosed at a younger age.AIM To investigate the association between age at diagnosis and the cardiovascular risk profile in adults with T2D.METHODS A pooled dataset was used,comprised of data from five previous studies of adults with T2D,including 1409 participants of whom 196 were diagnosed with T2D under the age of 40 years.Anthropometric and blood biomarker measurements included body weight,body mass index(BMI),waist circumference,body fat percentage,glycaemic control(HbA1c),lipid profile and blood pressure.Univariable and multivariable linear regression models,adjusted for diabetes duration,sex,ethnicity and smoking status,were used to investigate the association between age at diagnosis and each cardiovascular risk factor.RESULTS A higher proportion of participants diagnosed with T2D under the age of 40 were female,current smokers and treated with glucose-lowering medications,compared to participants diagnosed later in life.Participants diagnosed with T2D under the age of 40 also had higher body weight,BMI,waist circumference and body fat percentage,in addition to a more adverse lipid profile,compared to participants diagnosed at an older age.Modelling results showed that each one year reduction in age at diagnosis was significantly associated with 0.67 kg higher body weight[95%confidence interval(CI):0.52-0.82 kg],0.18 kg/m^(2) higher BMI(95%CI:0.10-0.25)and 0.32 cm higher waist circumference(95%CI:0.14-0.49),after adjustment for duration of diabetes and other confounders.Younger age at diagnosis was also significantly associated with higher HbA1c,total cholesterol,low-density lipoprotein cholesterol and triglycerides.CONCLUSION The diagnosis of T2D earlier in life is associated with a worse cardiovascular risk factor profile,compared to those diagnosed later in life. | Mary M Barker Francesco Zaccardi Emer M Brady Gaurav S Gulsin Andrew P Hall Joseph Henson Zin ZinHtike Kamlesh Khunti Gerald P McCann Emma L Redman David R Webb Emma G Wilmot Tom Yates Jian Yeo Melanie J Davies Jack A Sargeant | 2022 | World Journal of Diabetes2022，13，3： | 2 |
| 3 | The Use of Simvastatin for the Prevention of Gallstones in the Lithogenic Prairie Dog Model显示文摘 | Kurt G Davis MD Thomas M Wertin MD John P Schriver MD FACS | 2003 | Obesity Surgery2003，，6： | 2 |
| 4 | K-shell line ratio and powers for diagnosing cylindrical plasmas of neon, aluminum, argon and titanium显示文摘 | Apruzese J P Whitney K G Davis J | 1997 | Journal of Quantitative Spectroscopy and Radiation Transfer1997，57，1： | 1 |
| 5 | Electromagnetic determination of soil water content: measurement in coaxial transmission lines显示文摘 | Topp G C Davis J L Annan A P | 1980 | Water Resources Research1980，16，3： | 1 |
| 6 | Mutations of the BRAF gene in human cancer显示文摘 | Davies H Bignell G R Cox C Stephens P Edkins S Clegg S et al | 2002 | Nature2002，417，： | 1 |
| 7 | Hollow metal microneedles for insulin delivery to diabetic rats 显示文摘 | Davis S P Martanto W Allen M G | 2005 | IEEE Transactions on Biomedical Engineering2005，52，5： | 1 |
| 8 | Vasoreactivity of culprit lesion in unstable angina显示文摘 | Bogath P Hckeett D Davies G | 1994 | Circulation1994，90，5： | 1 |
| 9 | The formation of plasma membrane blebs in hepatocytes exposed to agents that increase cytosolic Ca2+ is mediated by the activation of a non-lysosomal proteolytic system显示文摘 | Nicotera P Hartzell P Davis G | 1986 | FEBS Lett1986，209，1： | 1 |
| 10 | The development and application of genetic markers for the Kuruma prawn Penaeus japonicus显示文摘 | Moore S S Whan V Davis G P | 1999 | Aquaculture1999，173，14： | 1 |
| 11 | Geologic development of the Cordille- ran metamorphic core complexes显示文摘 | Davis G H Coney P J | 1979 | Geology1979，7，： | 1 |
| 12 | Evidence for the presence of a major gene influencing ovulation rate on the X chromosome of sheep显示文摘 | Davis G H McEwan J C Fennessy P F | 1991 | Biol Reprod1991，44，4： | 1 |
| 13 | The involvement of cell-to-cell signals in the development of a bacterial biofilm显示文摘 | DAVIES D G PARSEK M R PEARSON J P | 1998 | Science1998，280，5361： | 1 |
| 14 | Tissue distribution of the AMP-activated protein kinase, and lack of activation by cyclic-AMP- dependent protein kinase, studied using a specific and sensitive peptide assay显示文摘 | DAVIES S P CARLING D HARDIE D G | 1989 | Eur J Biochem1989，186，12： | 1 |
| 15 | Vasoreactivity of the culprit lesion in unstable angina显示文摘 | Hackett D Davies G | 1994 | Circulation1994，90，1： | 1 |
| 16 | Electromagnetic determination of soil water content:measurements in coaxial transmission lines显示文摘 | TOPP G C DAVIS J L ANNAN A P | 1980 | Water Resources Research1980，16，3： | 1 |
| 17 | Tackling antibiotic resistance显示文摘 | Bush K Courvalin P Dantas G Davies J Eisenstein B Huovinen P Jacoby GA Kishony R Kreiswirth BN Kutter E Lerner SA Levy S Lewis K Lomovskaya O Miller JH Mobashery S Piddock LJ Projan S Thomas CM Tomasz A Tulkens PM Walsh TR Watson JD Witkowski J Witte W Wr | | 0，，： | 1 |
| 18 | Ex-pression patterns of cell wall-modifying enzymes during grape ber-ry development显示文摘 | NUNAN K J DAVIES C ROBINSON S P FINCHER G B | 2001 | Planta2001，214，2： | 1 |
| 19 | The use of high frequen- cy chest wall oscillation during an acute infective pulmonary exacerbation of cystic fibrosis 显示文摘 | Banks A Davies G Agent P | 2012 | European Respiratory Journal2012，40，56： | 1 |
| 20 | Styrene-siloxane ABA block copolymers 显示文摘 | DAVIES W G JONES D P | 1971 | Ind Eng Chem Prod Res Develop1971，10，2： | 1 |
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