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| 1 | Pentoxifylline 通过 TNF- 合成和 TGF-1 基因表示的下面规定改进肝新生显示文摘 AIM:To investigate the mechanism of pentoxifylline(PTX)improvement in liver regeneration.RESULTS:Rats were randomized into 4 groups:Control rats;Sham-sham-operation rats;Saline-70% hepatectomy plus saline solution;PTX-70%hepatectomy plus PTX.At 2 and 6 h after hepatectomy,aspartate aminotransferase,alanine aminotransferase,tumor necrosis factor(TNF)-α and interleukin-6(IL-6)serum and hepatic tissue levels were determined.Tumor growth factor(TGF)-β1 gene expression in liver tissue was evaluated 24 h after hepatectomy by quantitative reverse transcriptase polymerase chain reaction analysis.Proliferation was analyzed by mitotic index and proliferating cell nuclear antigen(PCNA)staining 48 h after hepatectomy.RESULTS:TNF-α and IL-6 serum levels increased at 2 and 6 h after hepatectomy.At 2 h after hepatectomy serum PTX was reduced but not hepatic levels of TNF-α and IL-6.A decrease in liver TGF-β1 gene expression and an increase in mitotic index and PCNA after hepatectomy were observed in the PTX treatment group in comparison to the saline group.CONCLUSION:PTX improves liver regeneration by a mechanism related to down regulation of TNF-α production and TGF-β1 gene expression. | Rodrigo Bronze Martino Ana Maria Mendona Coelho Márcia Saldanha Kubrusly Regina Leito Sandra Nassa Sampietre Marcel Cerqueira Cesar Machado Telesforo Bacchella Luiz Augusto Carneiro D’Albuquerque | 2012 | World Journal of Gastrointestinal Surgery2012，4，6： | 2 |
| 2 | The uric acid metabolism pathway as a therapeutic target in hyperuricemia related to metabolic syndrome显示文摘 | André a Name Colado Sim? o Marcell Alysson Batisti Lozovoy Isaias Dichi | 2012 | Expert Opinion on Therapeutic Targets2012，，12： | 2 |
| 3 | Determination of chlorine dioxide in concentrated solutions in the presence of chlorine显示文摘 | Marcel Lepeintre Jeanine D Jean O 1960 | 1960 | Chim Anal1960，42，： | 1 |
| 4 | Sensory investigation of yogurt flavor perception:mutual Influence of volatiles and acidity显示文摘 | Andreas O Alain H Marcel B | 2000 | Journal Agricahure Food Chemistry2000，48，2： | 1 |
| 5 | Timing-dependent protection of hypertonic saline solution administration in experimental liver ischemia/reperfusion injury显示文摘 | Estela Regina Ramos Figueira Telesforo Bacchella Ana Maria Mendon?a Coelho Sandra Nassa Sampietre Nilza Aparecida Trindade Molan Regina Maria Cubero Leit?o Marcel Cerqueira Cesar Machado | 2010 | Surgery2010，，3： | 1 |
| 6 | Reduced-energy cranberry juice increases folic acid and adiponectin and reduces homocysteine and oxidative stress in patients with the metabolic syndrome显示文摘 | Tathiana Name Colado Sim?o Marcell Alysson Batisti Lozovoy Andréa Name Colado Sim?o Sayonara Rangel Oliveira Danielle Venturini Helena Kaminami Morimoto Lúcia Helena Silva Miglioranza Isaias Dichi | 2013 | British Journal of Nutrition2013，，10： | 1 |
| 7 | Continuous enzymatic regeneration of electron acceptors used by flavoenzyrnes: cellobiose de- hydrogenase-eatalyzed production of lactobionic acid as an example显示文摘 | ROLAND L MAGDALENA O MARCEL Z | 2004 | Biocat Biotransf2004，22，2： | 1 |
| 8 | Esophagogastric junction outflow obstruction successfully treated with laparoscopic Heller myotomy and Dor fundoplication: First case report in the literature显示文摘BACKGROUND Esophagogastric junction outflow obstruction(EGJOO) is a rare syndrome,characterized by an elevation of the integrated relaxation pressure of the lower esophageal sphincter, not accompanied by alterations in esophageal motility that may lead to the criteria for achalasia. We were unable to find any prior report of the combination of Heller myotomy with anterior partial fundoplication(Dor) as the treatment for EGJOO. We herein report a case of EGJOO treated with laparoscopic Heller myotomy combined with Dor fundoplication.CASE SUMMARY A 26-year-old man presented with a 3-year history of solid dysphagia and a 30-kg weight loss. He was treated with oral nifedipine, isosorbide, and omeprazole,without resolution of symptoms. An upper gastrointestinal series(barium swallow) revealed a 'bird's beak' sign. Esophagogastroduodenoscopy was positive for Los Angeles grade A peptic esophagitis. High-resolution esophageal manometry was compatible with EGJOO. Esophageal pH monitoring showed pathological acid reflux both in orthostatic and decubitus position. An 8-cm laparoscopic Heller myotomy combined with an anterior 220° Dor fundoplication was performed. Solid diet was introduced on postoperative day 2, and the patient was discharged home the same day. At 17-mo follow-up, he reported no symptoms. Barium swallow was compatible with complete radiologic resolution.Both esophageal manometry and upper endoscopy showed normal findings 9 mo after the operation.CONCLUSION Surgical treatment with Heller myotomy and Dor fundoplication is a potential treatment option for EGJOO refractory to medical treatment. | Pedro F Pereira Andre RP Rosa Leonardo A Mesquita Marcelle J Anzolch Rafael N Branchi Augusto L Giongo Francisco C Paix?o Marcio F Chedid Cleber DP Kruel | 2019 | World Journal of Gastrointestinal Surgery2019，11，2： | 1 |
| 9 | Catabolism of the human erythrocyte C3 b/C4b receptor ( CR1, CD35 ): vesiculation and/or proteolysis 显示文摘 | Steophane O Marcelle T | 1997 | I mmunopharmacology1997，38，1： | 1 |
| 10 | Timing-dependent protection of hypertonic saline solution administration in experimental liver ischemia/reperfusion injury显示文摘 | Estela Regina Ramos Figueira Telesforo Bacchella Ana Maria Mendon?a Coelho Sandra Nassa Sampietre Nilza Aparecida Trindade Molan Regina Maria Cubero Leit?o Marcel Cerqueira Cesar Machado | 2010 | Surgery2010，，3： | 1 |
| 11 | Phil- ipp, Imaging of the scrotum in children 显示文摘 | Marcus Hormarm Csilla Balassy Marcel O | 2004 | Eur Radiol2004，，14： | 1 |
| 12 | Insulin-like growth factor (IGF)-I, IGF binding protein-3, and cancer risk: systematic review and meta-regression analysis显示文摘 | Andrew G Renehan Marcel Zwahlen Christoph Minder Sarah T O’Dwyer Stephen M Shalet Matthias Egger | 2004 | The Lancet2004，，9418： | 1 |
| 13 | Genetic diversity of six populations of red hybrid tilapia,using microsatellite genetic markers显示文摘 | Boris Brinez Xenia Caraballo O and Marcel Salazar V | 2011 | Rev MVZ Cor- doba2011，16，2： | 1 |
| 14 | Catabolism of the human crythrocyte C3/C4b receptor( CR1, CD35 ) :vesiculation and/or proteolysis 显示文摘 | Xavier D Steophane O Marcelle T | 1997 | Immunopharmacology1997，38，1： | 1 |
| 15 | Beneficial Effects Of Lactobacillus Plantarum On Glycemia And Homocysteine Levels In Postmenopausal Women With Metabolic Syndrome: A Pilot Study显示文摘 | Fabíola Málaga Barreto Andréa Name Colado Sim?o Helena Kaminami Morimoto Marcell Alysson Batisti Lozovoy Isaias Dichi Lúcia Helena da Silva Miglioranza | 2013 | Nutrition2013，，： | 1 |
| 16 | Synthesis and characterization of montmorillonite clay intercalated with molecular magnetic compounds显示文摘 | Marcel G Martins Daniel O Martins T A | 2015 | Solid State Chemistry2015，228，8： | 1 |
| 17 | Catabolism of the human erythrocyte C3b/C4b receptor (CR1, CD35): vesiculation and/or proteolysis显示文摘 | Xavier D Steophane O Marcelle T | 1997 | Immunopharmacology1997，38，1： | 1 |
| 18 | Stromal myofibroblasts are drivers ofinvasive cancer growth显示文摘 | De Wever O Demetter P Marcel M | 2008 | IntJ Cancer2008，123，10： | 1 |
| 19 | Catabolism of the human erythrocyte C3b/C4b receptor ( CR1, CD35) : vesiculation and / or proteolysis显示文摘 | Xavier D Steophane O Marcelle T | 1997 | Immunopharmacology1997，38，1： | 1 |
| 20 | ErbB3 binding protein-l(Ebpl)controls proliferation and myogenic differentiation of muscle stem cells显示文摘 | Figeac N Serralbo O Marcelle C et ol | 2014 | Developmental Biology2014，386，1： | 1 |
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