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| 1 | 使用互相关和双差法对北加州20年的地震活动进行大范围重定位显示文摘采用双差(DD)定位算法同时结合波形互相关(CC)方法,重新分析了北加州近20年(1984~2003)的数字化地震资料,将北加州地震台网(NCSN)现有地震目录中震源的定位精度提高了3个数量级。定位过程中结合使用了由所有震中距离不超过5km的相关事件对测得的30亿个互相关到时差数据以及北加州地震台网观测报告中列出的700万个P波到时读数。双差法重定位后获得311273个事件。重定位后的地震目录能够勾画出非常精细的、与活断层相关的地震活动构造图像,并且能够揭示诸如地震条带、重复地震等的时空构造特征。结果显示,约有90%的地震在同一个台站具有相关的P波、S波列,并且有12%的事件属于重复地震。通过对重复地震的分析认为,在95%置信水平下,现有台网定位的不确定性在水平方向平均约0.7km,垂直方向平均约2km。地震事件的相关性以及重定位后相对位置的改善在北加州大部分地区非常一致,这就意味着使用该方法高精度地确定由不同板块构造或者人为因素造成的地震活动图像是普遍适用的。本文认为,长期的、一致性好的地震监测以及数据分析工作是提高现有震源目录中地震定位精度和以后精确定位日常化的关键问题。 | F. Waldhauser D. P. Schaff 黄媛(译) 张天中(校) | 2008 | 世界地震译丛2008，39，5： | 24 |
| 2 | Changes in lipid metabolism in chronic hepatitis C显示文摘AIM: To investigate the relationship between certain biochemical parameters of lipid metabolism in the serum and steatosis in the liver.METHODS: The grade of steatosis (0-3) and histological activity index (HAI, 0-18) in liver biopsy specimens were correlated with serum alanine aminotransferase (ALT), total cholesterol and triglyceride levels in 142 patients with chronic hepatitis C (CH-C), and 28 patients with non-alcoholic fatty liver disease (NAFLD) without hepatitis C virus (HCV) infection. The serum parameters were further correlated with 1 797 age and sex matched control patients without any liver diseases.RESULTS: Steatosis was detected in 90 out of 142 specimens (63%) with CH-C. The ALT levels correlated with the grade of steatosis, both in patients with CH-C and NAFLD (P<0.01). Inserting the score values of steatosis as part of the HAI, correlation with the ALT level (P<0.00001) was found. The triglyceride and cholesterol levels were significantly lower in patients with CH-C (with and without steatosis), compared to the NAFLD group and to the virus-free control groups.CONCLUSION: Our study confirms the importance of liver steatosis in CH-C which correlates with lower lipid levels in the sera. Inclusion of the score of steatosis into HAI, in case of CH-C might reflect the alterations in the liver tissue more precisely, while correlating with the ALT enzyme elevation. | Katalin Jármay Gizella Karácsony András Nagy Zsuzsa Schaff | 2005 | World Journal of Gastroenterology2005，11，41： | 22 |
| 3 | mi R-122 negatively correlates with liver fibrosis as detected by histology and FibroScan显示文摘AIM: To investigate whether expression of selected mi RNAs obtained from fibrotic liver biopsies correlate with fibrosis stage.METHODS: Altogether, 52 patients were enrolled in the study representing various etiologic backgrounds of fibrosis: 24 cases with chronic hepatitis infections(types B, C), 19 with autoimmune liver diseases(autoimmune hepatitis, primary biliary cirrhosis, primary sclerosing cholangitis, overlapping syndrome cases), and 9 of mixed etiology(alcoholic and nonalcoholic steatosis, cryptogenic cases). Severity of fibrosis was determined by both histologic staging using the METAVIR scoring system and noninvasive transient elastography. Following RNAisolation, expression levels of mi R-21, mi R-122, mi R-214, mi R-221, mi R-222, and mi R-224 were determined using Taq Man Micro RNA Assays applying mi R-140 as the reference. Selection of mi RNAs was based on their characteristic up- or downregulation observed in hepatocellular carcinoma. Relative expression of mi RNAs was correlated with fibrosis stage and liver stiffness(LS) value measured by transient elastography, as well as with serum alanine aminotransferase(ALT) level.RESULTS: The expression of individual mi RNAs showed deregulated patterns in stages F1-F4 as compared with stage F0, but only the reduced level of mi R-122 in stage F4 was statistically significant(P < 0.04). When analyzing mi RNA expression in relation to fibrosis, levels of mi R-122 and mi R-221 showed negative correlations with fibrosis stage, and mi R-122 was found to correlate negatively and mi R-224 positively with LS values(all P < 0.05). ALT levels displayed a positive correlation with mi R-21(P < 0.04). Negative correlations were observed in the fibrosis samples of mixed etiology between mi R-122 and fibrosis stage and LS values(P < 0.05), and in the samples of chronic viral hepatitis, between mi R-221 and fibrosis stage(P < 0.01), whereas mi R-21 showed positive correlation with ALT values in the samples of autoimmune liver diseases(P < 0.03). The results also revealed a strong correlation between fibrosis stage and LS values(P < 0.01) when etiology of fibrosis was not taken into account.CONCLUSION: Reduced expression of mi R-122 in advanced fibrosis and its correlation with fibrosis stage and LS values seem to be characteristic of hepatic fibrosis of various etiologies. | Tünde Halász Gábor Horváth Gabriella Pár Klára Werling András Kiss Zsuzsa Schaff Gábor Lendvai | 2015 | World Journal of Gastroenterology2015，21，25： | 11 |
| 4 | 室间隔切除术:治疗梗阻性肥厚型心肌病的金标准显示文摘梗阻性肥厚型心肌病(HCM)间隔切除术的治疗方法几乎与HCM文献报道同时出现。现在越来越清楚的表明,间隔切除术是一种缓解流出道梗阻症状最可靠的治疗方法。间隔切除术在HCM治疗中地位的不断提高,主要是因为:(1)对梗阻的患病率及其影响认识更加清楚;(2)通过与酒精消融术的比较,使我们对该术式的认识更加清楚。下面我们介绍一下Mayo医院外科治疗HCM的经验。 | Joseph A Dearani Hartzell V Schaff Steve R Ommen | 2009 | 中华心血管病杂志2009，37，4： | 7 |
| 5 | Elevated miR-33a and miR-224 in steatotic chronic hepatitis Cliver biopsies显示文摘AIM:To assess the expression of selected microRNAs(miRNA) in hepatitis C,steatotic hepatitis C,noninfected steatotic and normal liver tissues.METHODS:The relative expression levels of miR-21,miR-33 a,miR-96,miR-122,miR-125 b,miR-221 and miR-224 were determined in 76 RNA samples isolated from 18 non-steatotic and 28 steatotic chronic hepatitis C(CHC and CHC-Steatosis,respectively) cases,18 non-infected,steatotic liver biopsies of metabolic origin(Steatosis) and 12 normal formalin-fixed paraffin-embedded liver tissues using TaqMan MicroRNA Assays.All CHC biopsy samples were obtained prior to initiating therapy.Patients' serum biochemical values,which included glucose,triglyceride,cholesterol,alanine aminotransferase(ALT),aspartate aminotransferase(AST),gamma-glutamyl-transferase(GGT),alkaline phosphatase(AP),were obtained and correlated with relative miRNA expression.RESULTS:When compared with control non-infected liver samples,miR-122 and miR-221 levels were reduced in CHC-Steatosis(P < 0.03) and in CHC,CHCSteatosis and Steatosis(P < 0.01).Alternatively,the expression of miR-33 a and miR-224 were elevated in CHC-Steatosis and Steatosis in comparison to control tissue(P < 0.01).The levels of miR-33 a and miR-224 in CHC-Steatosis(P < 0.02) and miR-224 in Steatosis(P < 0.001) were increased in comparison to CHC samples.By contrast,the expression of miR-21 did not differ statistically between diseased and normal liver samples.Levels of miR-33 a correlated negatively with serum AST and AP levels in Steatosis as well as with necroinflammatory grade in CHC,whereas miR-21 correlated positively with AST in Steatosis and displayed negative correlation with triglyceride level in CHC-Steatosis.In contrast,miRNA levels were not correlated with ALT,GGT,cholesterol levels or fibrosis stage.CONCLUSION:Differences in miRNA expression were observed between CHC and steatotic CHC,CHC and steatotic liver,but not between steatotic CHC and steatotic liver of metabolic origin. | Gabor Lendvai Katalin Jármay Gizella Karácsony Tünde Halász Ilona Kovalszky Kornélia Baghy Tibor Wittmann Zsuzsa Schaff András Kiss | 2014 | World Journal of Gastroenterology2014，20，41： | 2 |
| 6 | Holmes-Adie syndrome, autoimmune hepatitis and celiac disease: A case report显示文摘与 Holmes-Adie 的下列症状介绍的一个 35 岁的女病人:畏光,对光无答复的左学生的增大,阿奇里斯无反射。毛果芸香硷测试是阳性的。没有肿瘤或另外的神经病学的反常被发现。她有自体免疫的肝炎的 19 年的历史。闪光在上面被观察跟随每 3 交货。在 31 的年龄,她与腹泻和重量损失介绍了。腹的肿瘤被超声检测。通过手术移开的肿瘤是组织学地良性的 mes 伤寒多膀胱的淋巴管瘤。同时,乳糜泻是 diagnosed.Gluten 免费的饮食导致了乳糜泻,然而并非自体免疫的肝炎的重要改进。自治神经病被标准心血管的测试证明。病人是为为乳糜泻特征、为在自体免疫的肝疾病经常的 HLA DR3 B8 异质接合的 HLA DQ2 抗原的一个同型结合的搬运人。我们有自体免疫的肝炎和乳糜泻的 Holmes-Adie 的协会上的新奇观察为为在有 mes 伤寒的一个病人在场的所有三个实体的一个普通免疫学的背景是暗示的多膀胱的淋巴管瘤。 | Timea Csak Aniko Folhoffer Andrea Horvath Judit Halász Csaba Diczházi Zsuzsa Schaff Ferenc Szalay | 2006 | World Journal of Gastroenterology2006，12，9： | 1 |
| 7 | The role of the oxygen free radical system in the calcium paradox,the oxygen paradox,and ischemia reperfusion injury显示文摘 | Hess ML Manson NH Schaff HV | 1984 | J MOL Cell Cardiol1984，16，： | 1 |
| 8 | Cox-maze Procedure for Atrial Fibrillation:Mayo Clinic Experience显示文摘 | Schaff H V Dearani J A Daly R C | 2000 | Semin Thorac Cardiovasc Surg2000，12，1： | 1 |
| 9 | Impact of preoperative symptoms on survival after surgical correction of organic mitral regurgitation:rationale for optimizing surgical indications显示文摘 | Tribouilloy CM Enriquez-Sarano M Schaff HV | | 0，，03： | 1 |
| 10 | Double-orifice left atrioventricular valve in patients with atrioventricular septal defects:surgical strategies and outcome显示文摘 | Sharma V Burkhart HM Schaff HV | | 0，，06： | 1 |
| 11 | Congenitally Corrected Transposition of Great Arteries Surgical Options for the Failing Right Ventricle and/or Severe Tricuspid Regurgitation显示文摘 | Said SM Burkhart HM Schaff HV | 2011 | World J Pediatr Congenit Heart Surg2011，2，1： | 1 |
| 12 | Cox-Maze procedure for atriaL fibrillation:Mayo clinic experience显示文摘 | Schaff HV Dearani JA Daly RC | 2000 | Semin Thorac Cardiovasc Surg2000，12，1： | 1 |
| 13 | Very long-term survival and durability of mitral valve repair for mitral valve prolapse 显示文摘 | Mohty D Orszulak TA Schaff HV | 2001 | Circulation2001，104，121： | 1 |
| 14 | Shoes for the insensitive foot~ The effect of a rocker bottom shoe modification on plantar pressure distribution显示文摘 | Schaff P S Cavanagb P R | 1990 | Foot Ankle1990，11，： | 1 |
| 15 | Life prediction methodology for composite structures, Part Ⅰ-constant amplitude and two-stress level fatigue显示文摘 | SCHAFF J R DAVIDSON B D | 1997 | Journal of Composite Materials1997，31，： | 1 |
| 16 | Acute aortic dissection:population-based incidence compared with degenerative aortic aneurysm rupture显示文摘 | Clouse WD Hallett JW Jr Schaff HV | | 0，，： | 1 |
| 17 | Acute aortic dissection: population based incidence compared with degenerative aortic aneurysm rupture显示文摘 | Clouse W D Hallett J W Jr Schaff H V | 2004 | Mayo Clin Proc2004，79，2： | 1 |
| 18 | Temperature dependence of performance of In-GaN/GaN MQW LEDs with different indium compo-sitions显示文摘 | Huh Chul Schaff William J Eastman Lester F | 2004 | IEEE Electron Device Letters2004，25，2： | 1 |
| 19 | Evaluation and compari- son of the clinical, surgical and pathological TNM staging of colorectal cancer显示文摘 | Harisi R Schaff Z Flautner L | 2008 | Hepatogastroenterology2008，55，81： | 1 |
| 20 | Echocardiographic prediction of left ventricular function after correction of mitral regurgitation:results and clinical implications显示文摘 | Enriquez-Saiano M Tajik AJ Schaff HV | | 0，，： | 1 |
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