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| 1 | Ⅰ期癌症患者切除淋巴结内隐匿性微小转移癌灶的检查及其临床病理意义显示文摘目的 检查癌症患者切除淋巴结内有无微小癌转移 ,具有临床、病理重要性。方法 350例 期癌症患者包括非小细胞肺癌 94例 ,乳腺癌 112例 ,食管癌 115例及外阴癌 2 9例病理报告无癌转移的淋巴结 3715枚。应用单克隆抗细胞角蛋白 ( AE1/ AE3)、抗上皮细胞膜 ( EMA) ,及多克隆抗角蛋白抗体进行免疫组化染色重新检查。结果 所有病例的 32 .3% ( 113/ 350 )、被检淋巴结的 5.5%( 2 0 3/ 3715)有淋巴结内隐匿性肿瘤转移。肺癌患者及被检淋巴结的阳性率均比其他肿瘤高。肺鳞癌58%、腺癌 53.8%的淋巴结为阳性 ,分别比食管鳞癌 2 2 .5%、外阴鳞癌 10 .3%及乳腺癌 2 7.7%高 ( P<0 .0 5)。部分乳腺癌患者术后随访显示 :淋巴结阳性患者比阴性者预后更差 ( P<0 .0 5)。结论 说明免疫组化技术可大大提高淋巴结微小癌转移的检出率 ,其阳性率的不同可能与患者的临床经过甚至癌患者的死亡率相关联。 | 陈朝伦 卢晓梅 黄绒 黎音 古丽娜尔 沈宝茵 A J Cochran D R Wen W F Coulson | 1997 | 中华肿瘤杂志1997，19，1： | 16 |
| 2 | Upper bounds on a two-term exponential sum显示文摘We obtain upper bounds for mixed exponential sums of the type S(x,f,pm) =bx)where pm is a prime power with m ≥ 2 and x is a multiplicative character 2(mod pm). If x is primitive or p\( a, b) then we obtain | S(x, f, pm) | ≤2np2-3m. If x is of conductor p and p\( a, b) then we get the stronger bound | S(x, f, pm) | ≤ npm/2. | Todd COCHRANE 郑志勇 | 2001 | Science China Mathematics2001，44，8： | 8 |
| 3 | Big data analytics with applications显示文摘In this paper,recent developments on the Internet of Things(IoT)and its applications are surveyed,and the impact of newly developed Big Data(BD)on manufacturing information systems is especially discussed.Big Data analytics(BDA)has been identified as a critical technology to support data acquisition,storage,and analytics in data management systems in modern manufacturing.The purpose of the presented work is to clarify the requirements of predictive systems,and to identify research challenges and opportunities on BDA to support cloudbased information systems. | Zhuming Bi David Cochran | 2014 | Journal of Management Analytics2014，1，4： | 5 |
| 4 | The liver diseases of lipodystrophy: The long-term effect of leptin treatment显示文摘 | Elika Safar Zadeh Andreea O. Lungu Elaine K. Cochran Rebecca J. Brown Marc G. Ghany Theo Heller David E. Kleiner Phillip Gorden | 2013 | Journal of Hepatology2013，，1： | 3 |
| 5 | Organic enrichment of sediments from salmon farming in Norway: environmental factors, management practices, and monitoring techniques显示文摘 | Michael L Carroll Sabine Cochrane Reinhold Fieler Roger Velvin Patrick White | 2003 | Aquaculture2003，，1： | 2 |
| 6 | Probability distributions of extreme pressure coefficients显示文摘 | J.D. Holmes L.S. Cochran | 2003 | Journal of Wind Engineering & Industrial Aerodynamics2003，，7： | 2 |
| 7 | Hyperglycemia, Insulin Resistance, Impaired Pancreatic β-Cell Function, and Risk of Pancreatic Cancer显示文摘 | Brian M. Wolpin Ying Bao Zhi Rong Qian Chen Wu Peter Kraft Shuji Ogino Meir J. Stampfer Kaori Sato Jing Ma Julie E. Buring Howard D. Sesso I-Min Lee John Michael Gaziano Anne McTiernan Lawrence S. Phillips Barbara B. Cochrane Michael N. Pollak JoAnn E. Ma | 2013 | JNCI Journal of the National Cancer Institute2013，，14： | 2 |
| 8 | Is MAGE-1 expression in metastatic malignant melanomas really helpful 显示文摘 | Gajjar NA Cochran AJ Binder SW | 2004 | Am J Surg Pathol2004，28，7： | 1 |
| 9 | Soil seed bank changes after forest clearing and agricultural use in Alaska显示文摘 | CONN J S COCHRANE C L DELAPP J A | 1984 | Weed Science1984，32，3： | 1 |
| 10 | Pedagogical content knowing:An integrative model for teacher preparation显示文摘 | Cochran Kathryn F DeRuiter James A King Richard A | 1993 | Journal of Teacher Education1993，44，4： | 1 |
| 11 | Production based asset pricing and the link between stock returns and economic fluctuations显示文摘 | Cochrane J | 1991 | Journal of Finance1991，，46： | 1 |
| 12 | Hidradenocarcinoma:a histological andimmunohistochemical study显示文摘 | KO C J COCHRAN A J ENG W | 2006 | J Cutan Pathol2006，33，11： | 1 |
| 13 | A cross-sectional test of an investment-based asset pricing model显示文摘 | Cochrane J H | 1996 | Journal of Political Economy1996，104，： | 1 |
| 14 | Mode propagation in continuously curved waveguide 显示文摘 | Cochran J A Pecina R G | 1966 | Radio Science1966，1，6： | 1 |
| 15 | Plasma folate, vitamin B6, vitamin B12, and homo- cysteine and pancreatic cancer risk in four large cohorts显示文摘 | Schernhammer E Wolpin B Rifai N Cochrane B Manson J A Ma J | 2007 | Cancer Res2007，67，： | 1 |
| 16 | Cloning and sequencing of human thioredoxin reductase 显示文摘 | Gasdaska PY Gasdaska JR Cochran S Powis G | 1995 | FEBS Lett1995，373，1： | 1 |
| 17 | Moving reflector type micro optical switch for high-power transfer in a MEMS-based safety and arming system显示文摘 | Cochran K R Fan L DeVoe D L | 2004 | J Microryzech Microeng2004，14，： | 1 |
| 18 | Corporate Social Responsibility and Stock Market Performance 显示文摘 | Cochran P Wood R | 1984 | Academy of Management Journal1984，27，： | 1 |
| 19 | The scientific basis for clinical experiences with Straumann implants including the ITI dental implant system: a consensus report 显示文摘 | Cochran DL | 2000 | Clin Oral Implant Res2000，11，1： | 1 |
| 20 | p50(cdc37) binds directly to the catalytic domain of Raf as well as to a site on hsp90 that is topologically adjacent to the tetratricopeptide repeat binding site显示文摘 | Silverstein AM Grammatikakis N Cochran BH | 1998 | J Biol Chem1998，273，20： | 1 |
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