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| 1 | H7N9 virulent mutants detected in chickens in China pose an increased threat to humans显示文摘 | Jianzhong Shi Guohua Deng Huihui Kong Chunyang Gu Shujie Ma Xin Yin Xianying Zeng Pengfei Cui Yan Chen Huanliang Yang Xiaopeng Wan Xiurong Wang Liling Liu Pucheng Chen Yongping Jiang Jinxiong Liu Yuntao Guan Yasuo Suzuki Mei Li Zhiyuan Qu Lizheng Guan Jinkai Zang Wenli Gu Shuyu Han Yangming Song Yuzhen Hu Zeng Wang Linlin Gu Wenyu Yang Libin Liang Hongmei Bao Guobin Tian Yanbing Li Chuanling Qiao Li Jiang Chengjun Li Zhigao Bu Hualan Chen | 2017 | Cell Research2017,27,12: | 70 |
| 2 | RGB WGM lasing woven in fiber braiding cavity显示文摘It is critical to realize woven and wearable red-green-blue(RGB) whispering gallery mode(WGM)lasing that is tunable and flexible in the fiber braiding cavity. However, it is still a challenge to achieve tunable full-color lasing with the large color gamut by a facile approach. Here, we design the braiding cavity to realize RGB WGM lasing with high performance. The braiding cavity consists of three optical fibers coated with dye-doped polymer. Each fiber therein serves as a resonant cavity to support multiple lasing modes. There is no interference owing to the air gap between them;therefore, we can achieve full-color WGM lasing. The lasing emission in our fiber braiding cavity covers a color gamut of 86.7% larger than standard RGB space.Our work may provide a platform for potential applications in white laser and integrated optoelectronic devices. | Kun GE Zhiyang XU Dan GUO Ben NIU Jun RUAN Libin CUI Tianrui ZHAI | 2022 | Science China(Information Sciences)2022,65,8: | 2 |
| 3 | DOA ESTIMATION USING A SPARSE LINEAR MODEL BASED ON EIGENVECTORS显示文摘To reduce high computational cost of existing Direction-Of-Arrival(DOA) estimation techniques within a sparse representation framework,a novel method with low computational com-plexity is proposed.Firstly,a sparse linear model constructed from the eigenvectors of covariance matrix of array received signals is built.Then based on the FOCal Underdetermined System Solver(FOCUSS) algorithm,a sparse solution finding algorithm to solve the model is developed.Compared with other state-of-the-art methods using a sparse representation,our approach also can resolve closely and highly correlated sources without a priori knowledge of the number of sources.However,our method has lower computational complexity and performs better in low Signal-to-Noise Ratio(SNR).Lastly,the performance of the proposed method is illustrated by computer simulations. | Wang Libin Cui Chen Li Pengfei | 2011 | Journal of Electronics(China)2011,28,4: | 2 |
| 4 | DIRECTION-OF-ARRIVAL ESTIMATION IN THE PRESENCE OF MUTUAL COUPLING BASED ON JOINT SPARSE RECOVERY显示文摘A novel Direction-Of-Arrival (DOA) estimation method is proposed in the presence of mutual coupling using the joint sparse recovery. In the proposed method, the eigenvector corresponding to the maximum eigenvalue of covariance matrix of array measurement is viewed as the signal to be represented. By exploiting the geometrical property in steering vectors and the symmetric Toeplitz structure of Mutual Coupling Matrix (MCM), the redundant dictionaries containing the DOA information are constructed. Consequently, the optimization model based on joint sparse recovery is built and then is solved through Second Order Cone Program (SOCP) and Interior Point Method (IPM). The DOA estimates are gotten according to the positions of nonzeros elements. At last, computer simulations demonstrate the excellent performance of the proposed method. | Wang Libin Cui Chen | 2012 | Journal of Electronics(China)2012,29,5: | 2 |
| 5 | Improved spa- tial learning performance of fat - 1 mice is associated with enhanced neurogenesis and neuritogenesis by docosahexae- noic acid 显示文摘 | HE Chengwei QU Xiying CUI Libin | 2009 | PNAS2009,106,11: | 1 |
| 6 | Microstructures and properties of superlight Mg–Li–Al–Zn wrought alloys显示文摘 | Xiangrui Meng Ruizhi Wu Milin Zhang Libin Wu Chongliang Cui | 2009 | Journal of Alloys and Compounds2009,,1: | 1 |
| 7 | Application of ERA5 Reanalysis to the Construction of Initial Conditions for WACCM Simulations显示文摘This study uses ECMWF fifth-generation reanalysis, ERA5, which extends to the mesopause, to construct the Initial Conditions(IC) for WACCM(Whole Atmosphere Community Climate Model) simulations. Because the biases between ERA5 and Sounding of the Atmosphere using Broadband Emission Radiometry(SABER) temperature data are within ±5 K below the lower mesosphere,ERA5 reanalysis is used to construct IC in the lower atmosphere. Four experiments are performed to simulate a Stratospheric Sudden Warming(SSW) event from 5 to 15 February 2016. The simulation using the WACCM default climatic IC cannot represent the sharp meteorological variation during SSW. In contrast, the 0~4 d forecast results driven by ERA5-constructed IC is consistent with ERA5 reanalysis below the middle mesosphere. Comparing with WACCM climatology ICs scheme, the ICs constructing method based on ERA5 reanalysis can obtain 67%, 40%, 22%, 4% and 6% reduction of temperature forecast RMSE at 10 hPa, 1 hPa, 0.1 hPa, 0.01 hPa and 0.001 hPa respectively. However,such improvement is not shown in the lower thermosphere. | WANG Yegui JING Wenqi CUI Yuanyuan CAI Qifa LAN Weiren FANG Hanxian WENG Libin NIU Jun | 2018 | 空间科学学报2018,38,4: | 1 |
| 8 | PKD3 promotes metastasis and growth of oral squamous cell carcinoma through positive feedback regulation with PD-L1 and activation of ERK-STAT1/3-EMT signalling显示文摘Oral squamous cell carcinoma(OSCC)has a high incidence of metastasis.Tumour immunotherapy targeting PD-L1 or PD-1 has been revolutionary;however,only a few patients with OSCC respond to this treatment.Therefore,it is essential to gain insights into the molecular mechanisms underlying the growth and metastasis of OSCC.In this study,we analysed the expression levels of protein kinase D3(PKD3)and PD-L1 and their correlation with the expression of mesenchymal and epithelial markers.We found that the expression of PKD3 and PD-L1 in OSCC cells and tissues was significantly increased,which correlated positively with that of mesenchymal markers but negatively with that of epithelial markers.Silencing PKD3 significantly inhibited the growth,metastasis and invasion of OSCC cells,while its overexpression promoted these processes.Our further analyses revealed that there was positive feedback regulation between PKD3 and PD-L1,which could drive EMT of OSCC cells via the ERK/STAT1/3 pathway,thereby promoting tumour growth and metastasis.Furthermore,silencing PKD3 significantly inhibited the expression of PD-L1,and lymph node metastasis of OSCC was investigated with a mouse footpad xenograft model.Thus,our findings provide a theoretical basis for targeting PKD3 as an alternative method to block EMT for regulating PD-L1 expression and inhibiting OSCC growth and metastasis. | Bomiao Cui Jiao Chen Min Luo Yiying Liu Hongli Chen Die Lü Liwei Wang Yingzhu Kang Yun Feng Libin Huang Ping Zhang | 2021 | International Journal of Oral Science2021,13,1: | 1 |
| 9 | Application of conductive polymers in biocathode of microbial fuel cells and microbial community显示文摘 | Chao Li Lili Ding Hao Cui Libin Zhang Ke Xu Hongqiang Ren | 2012 | Bioresource Technology2012,,: | 1 |
| 10 | Effects of Ce-rich RE additions and heat treatment on the microstructure and tensile properties of Mg-Li-AI-Zn-based alloy显示文摘 | Wu Libin Cui Chongliang Wu Ruizhi | 2011 | Materials Science and Engineering:A2011,528,45: | 1 |
| 11 | Osteogenic and anti-tumor Cu and Mn-doped borosilicate nanoparticles for syncretic bone repair and chemodynamic therapy in bone tumor treatment显示文摘Critical bone defects caused by extensive excision of malignant bone tumor and the probability of tumor recurrence due to residual tumor cells make malignant bone tumor treatment a major clinical challenge.The present therapeutic strategy concentrates on implanting bone substitutes for defect filling but suffers from failures in both enhancing bone regeneration and inhibiting the growth of tumor cells.Herein,Cu and Mn-doped borosilicate nanoparticles(BSNs)were developed for syncretic bone repairing and anti-tumor treatment,which can enhance bone regeneration through the osteogenic effects of Cu^(2+) and Mn^(3+) ions and meanwhile induce tumor cells apoptosis through the hydroxyl radicals produced by the Fenton-like reactions of Cu^(2+) and Mn^(3+) ions.In vitro study showed that both osteogenic differentiation of BMSCs and angiogenesis of endothelial cells were promoted by BSNs,and consistently the critical bone defects of rats were efficiently repaired by BSNs through in vivo evaluation.Meanwhile,BSNs could generate hydroxyl radicals through Fenton-like reactions in the simulated tumor microenvironment,promote the generation of intracellular reactive oxygen species,and eventually induce tumor cell apoptosis.Besides,subcutaneous tumors of mice were effectively inhibited by BSNs without causing toxic side effects to normal tissues and organs.Altogether,Cu and Mn-doped BSNs developed in this work performed dual functions of enhancing osteogenesis and angiogenesis for bone regeneration,and inhibiting tumor growth for chemodynamic therapy,thus holding a great potential for syncretic bone repairing and anti-tumor therapy. | Libin Pang Renliang Zhao Jing Chen Jingxin Ding Xiaochen Chen Wenwen Chai Xu Cui Xiaolin Li Deping Wang Haobo Pan | 2022 | Bioactive Materials2022,7,6: | 1 |
| 12 | Improved spatial learn- ing performance of fat-1 mice is associated with enhanced neuro- genesis and neuritogenesis by docosahexaenoic acids 显示文摘 | Chengwei HE Xiying QU Libin CUI | 2009 | PNAS2009,106,11: | 1 |
| 13 | 2017年中国出现的H7N9高致病性病毒的快速进化显示文摘文章简介为了防控H7N9病毒,中国2017年9月开始对鸡进行了H5/H7二价禽流感灭活疫苗。为了解H7N9病毒在中国家禽中的分布情况,研究团队进行了系统的禽流感病毒监测。2017年2月至2017年5月之间在379个活禽市场和665个家禽养殖场共采集30201份样品(其中活禽市场采集12504份. | Jianzhong Shi Guohua Deng Shujie Ma Xianying Zeng Xin Yin Mei Li Bo Zhang Pengfei Cui Yan Chen Huanliang Yang Xiaopeng Wan Liling Liu Pucheng Chen Yongping Jiang Yuntao Guan Jinxiong Liu Wenli Gu Shuyu Han Yangming Song Libin Liang Zhiyuan Qu Yujie Hou Xiurong Wang Hongmei Bao Guobin Tian Yanbing Li Li Jiang Chengjun Li 陈化兰 | 2019 | 科学新闻2019,0,2: | 1 |
| 14 | CsPbI nanorods as the interfacial layer for high-performance,all-solution-processed self-powered photodetectors显示文摘Heterojunction is regarded as a crucial step toward realizing high-performance devices,particularly,forming gradient energy band between heterojunctions benefits self-powered photodetectors.Therefore,in this paper,the synthesis of CsPbI3 nanorods(NRs)and its application as the interfacial layer in high-performance,all-solution-processed self-powered photodetectors are presented.For the bilayer photodetector ITO/ZnO(100 nm)/PbS-TBAI(150 nm)/Au,a responsivity of 3.6 A/W with a specific detectivity of 9.8×10^(12)Jones was obtained under 0.1 mW/cm^(2)white light illumination at zero bias(i.e.in self-powered mode).Meanwhile,the photocurrent was enhanced to an On/Off current ratio of 105 at zero bias with an open circuit voltage of 0.53 V for trilayer photodetector ITO/ZnO(100 nm)/PbSTBAI(150 nm)/CsPbI3(250 nm)/Au,in which the CsPbI3 NRs layer works as the interfacial layer.As a result,a specific detectivity of 4.5×10^(13)Jones with a responsivity of 11.12 A/W was obtained under0.1 mW/cm^(2) white light illumination,as well as the rising/decaying time of 0.57 s/0.41 s with excellent stability and reproducibility upto four weeks in air.The enhanced-performance is ascribed to the mismatch bandgap between PbS-TBAI/CsPbI_(3)interface,which can suppress the carrier recombination and provide efficient transport passages for charge carriers.Thus,it provides a feasible and efficient method for high-performance photodetectors. | Muhammad Imran Saleem Shangyi Yang Attia Batool Muhammad Sulaman Chandrasekar Perumal Veeramalai Yurong Jiang Yi Tang Yanyan Cui Libin Tang Bingsuo Zou | 2021 | Journal of Materials Science & Technology2021,,16: | 1 |
| 15 | Research on Recommendation Algorithms Based on Cloud Models in Probabilistic Linguistic Environments显示文摘To solve the problem that the traditional cloud model can't directly process the textual review information in the recommendation algorithm,this paper combines the merits of the cloud model in transforming qualitative and quantitative knowledge with the multi-granularity advantages of probabilistic linguistic term sets in representing uncertain information,and proposes a recommendation algorithm based on cloud model in probabilistic language environment.Initially,this paper quantifies the attributes in the review text based on the probabilistic linguistic term set.Subsequently,the maximum deviation method is used to determine the weight of each attribute in the evaluation information of the product to be recommended,and the comprehensive evaluation number and attribute weight are converted into the digital characteristic value of the cloud model by using the backward cloud generator.Finally,the products are recommended and sorted based on the digital characteristic value of the cloud model.The algorithm is applied to the recommendation of 10 hotels,and the results show that the method is effective and practical,enriching the application of cloud models in the recommendation field. | Peng YANG Xifeng MA Meng WEI Chunsheng CUI Libin CHE | 2024 | Journal of Systems Science and Information2024,12,1: | 0 |
| 16 | A Laser Scanner-Stage Synchronized System Supporting the Large-Area Precision Polishing of Additive-Manufactured Metallic Surfaces显示文摘This paper proposes a scanner–stage synchronized approach emphasizing a novel control structure for the laser polishing of Inconel 718 components manufactured by selective laser melting in order to address increasing demands for high surface quality in metal additive manufacturing.The proposed synchronized control system is composed of a motion decomposition module and an error synthesis module.The experimental results show that stitching errors can be avoided thanks to continuous motion during laser processing.Moreover,in comparison with the existing step-scan method,the processing efficiency of the proposed method is improved by 38.22%and the surface quality of the laser-polished area is significantly enhanced due to a more homogeneous distribution of the laser energy during the material phase change.The proposed synchronized system paves the way for high-speed,high-precision,and large-area laser material processing without stitching errors. | Mengjia Cui Libin Lu Zhen Zhang Yingchun Guan | 2021 | Engineering2021,7,12: | 0 |
| 17 | Heterogeneous precipitate microstructure in titanium alloys for simultaneous improvement of strength and ductility显示文摘The design of alloys with simultaneous high strength and high ductility is still a difficult challenge.Here,we propose a new approach to designing multi-phase alloys with a synergistic combination of strength and ductility by engineering heterogeneous precipitate microstructures through the activation of different transformation mechanisms.Using a two-phase titanium alloy as an example,phase field simulations are carried out firstly to design heat treatment schedules that involve both conventional nucleation and growth and non-conventional pseudospinodal decomposition mechanisms,and the calculated microstructures have been evaluated by crystal plasticity finite element modeling.According to simulations,we then set a two-step heat treatment to produce bimodalα+βmicrostructure in Ti-10V-2Fe-3Al.Further mechanical testing shows that the ductility of the alloy is increased by~50%and the strength is increased by~10%as compared to its unimodal counterpart.Our work may provide a general way to improve the mechanical properties of alloys through multiscale microstructure design. | Mengyuan Hao Pei Li Xuexiong Li Tianlong Zhang Dong Wang Qiaoyan Sun Libin Liu Jinshan Li Yuyou Cui Rui Yang Dongsheng Xu | 2022 | Journal of Materials Science & Technology2022,,29: | 0 |
| 18 | 碳离子束辐射对大豆当代效应研究显示文摘Heavy-ion beam irradiation,as a powerful tool for mutation breeding,plays important rools for functional genomics studies in the post-genome era.In soybean,to screen the mutants with desirable agricultural characteristics can promote the production and development of China’s soybean industry in the future.In the present study,the seeds of cultivar Williams 82 were exposed to carbon-ion beam irradiation(Energy:80.55 MeV/u;Dose:0,60,80,100,120,150 and 180 Gy)that produced by the Heavy Ion Research Facility in Lanzhou(HIRFL).Biological endpoints including seedling rate,plant height and the phenotype were analyzed in this research. | Du Yan Yu Lixia Chen Xia Cui Tao Luo Shanwei Li Wenjian Zhou Libin | 2017 | IMP & HIRFL Annual Report2017,,1: | 0 |
| 19 | Versatile flexible micelles integrating mucosal penetration and intestinal targeting for effectively oral delivery of paclitaxel显示文摘The extremely low bioavailability of oral paclitaxel(PTX)mainly due to the complicated gastrointestinal environment,the obstruction of intestinal mucus layer and epithelium barrier.Thus,it is of great significance to construct a coordinative delivery system which can overcome multiple intestinal physicochemical obstacles simultaneously.In this work,a high-density PEGylation-based glycocholic acid-decorated micelles(PTX@GNPs)was constructed by a novel polymer,9-Fluorenylmethoxy carbonyl-poly ethylene glycocholic acid(Fmoc-PEG-GCA).The Fmoc motif in this polymer could encapsulate PTX viaπ-πstacking to form the core of micelles,and the low molecular weight and non-long hydrophobic chain of Fmoc ensures the high-density of PEG.Based on this versatile and flexible carriers,PTX@GNPs possess mucus trapping escape ability due to the flexible PEG,and excellent intestine epithelium targeting attributed to the high affinity of GCA with apical sodium-dependent bile acid transporter.The in vitro and in vivo results showed that this oral micelle could enhance oral bioavailability of PTX,and exhibited similar antitumor efficacy to Taxol injection via intravenous route.In addition,oral PTX@GNPs administered with lower dosage within shorter interval could increase in vivo retention time of PTX,which supposed to remodel immune microenvironment and enhance oral chemotherapy efficacy by synergistic effect. | Chao Liu Wei Liu Yanhong Liu Hongxia Duan Liqing Chen Xintong Zhang Mingji Jin Minhu Cui Xiuquan Quan Libin Pan Jiachun Hu Zhonggao Gao Yan Wang Wei Huang | 2023 | Acta Pharmaceutica Sinica B2023,13,8: | 0 |
| 20 | 4-35 Identification of Mutant Gene Induced by Carbon Ion Beams in Arabidopsis by Whole Genome Re-sequencing and Rough Map-based Cloning显示文摘In recent years,heavy ion beams have been recognized as an effective and efficient physical mutagen due to their capacity to induce mutations with high frequency and broad spectrum.Nowadays,it is not so difficult to produce various mutants in plants.However,to mine the responsible mutated genes has been an important challenge.For mutation isolation,map-based cloning is one of the major traditional ways to isolate the mutant genes that control traits of interest in forward genetics studies.However,the process of map-based cloning is usually complicated and time-consuming. | Du Yan Li Wenjian Yu Lixia Luo Shanwei Feng Hui Chen Yuze Mu Jinhu Cui Tao Chen Xia Zhou Libin | 2016 | IMP & HIRFL Annual Report2016,,1: | 0 |