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| 1 | Mutagenic and cytotoxic potential of Endosulfan and Lambda-cyhalothrin—In vitro study describing individual and combined effects of pesticides显示文摘Excessive use of pesticides poses increased risks to non target species including humans. In the developing countries, lack of proper awareness about the toxic potential of pesticides makes the farmer more vulnerable to pesticide linked toxicities, which could lead to diverse pathological conditions. The toxic potential of a pesticide could be determined by their ability to induce genetic mutations and cytotoxicity. Hence, determination of genetic mutation and cytotoxicity of each pesticide is unavoidable to legislate health and safety appraisal about pesticides. The objective of current investigation was to determine the genotoxic and cytotoxic potential of Endosulfan(EN) and Lambda-cyhalothrin(LC); individually and in combination. 3-(4,5-Dimethylthiazol-2-yl)-2,5-Diphenyltetrazolium Bromide(MTT) assay was utilized to determine cytotoxicity, while two mutant histidine dependent Salmonella strains(TA98, TA100) were used to determine the mutagenicity of EN and LC.Moreover, mutagenicity assay was conducted with and without S9 to evaluate the effects of metabolic activation on mutagenicity. Even though a dose dependent increase in the number of revertant colonies was detected with EN against both bacterial strains, a highly significant(p < 0.05) increase in the mutagenicity was detected in TA98 with S9. In comparison, data obtained from LC revealed less mutagenic potential than EN. Surprisingly,the non-mutagenic individual-concentrations of EN and LC showed dose dependent mutagenicity when combined. Combination of EN and LC synergistically induced mutagenicity both in TA98 and TA100. MTT assay spotlighted comparable dose dependent cytotoxicity effects of both pesticides. Interestingly, the combination of EN and LC produced increased reversion and cytotoxicity at lower doses as compared to each pesticide, concluding that pesticide exposure even at sub-lethal doses can produce cytotoxicity and genetic mutations, which could lead to carcinogenicity. | Umber Saleem Sohail Ejaz Muhammad Ashraf Muhammad Ovais Omer Imran Iltaf Zainab Batool Riffat Fatima Msbah Afzal | 2014 | Journal of Environmental Sciences2014，26，7： | 3 |
| 2 | Physiological and biochemical appraisal for mulching and partial rhizosphere drying of cotton显示文摘Water is the main factor for the healthy life of plant.One of the main negative effects of climate change is the increasing scarcity of water that is lethal for plant.Globally,for water deficit regions(arid and semi-arid),drought is the main factor responsible for low production of agriculture,especially for cotton.Great efforts have been and are being made to find alternatives to water saving practices.This study aimed to examine the effects of partial rhizosphere drying(PRD,half of the root system irrigated at one event,and the other half irrigated in the next event,and so on)with and/or without various mulching treatments on physiological and biochemical traits of cotton.To explore this objective,we laid out experiments in completely randomized design with factorial arrangement in the Islamia University of Bahawalpur,Pakistan in 2016.Two factors included were four mulching treatments(M0,no mulching;M1,black plastic mulching;M2,wheat straw mulching;and M3,cotton sticks mulching)and two irrigation levels(I0,control(full irrigation);and I1,PRD).Fisher's analysis of variance among means of treatments was compared using least significant difference test at 5% probability level.Results revealed that the maximum plant height,leaf area,leaf gas exchange(photosynthetic rate and stomata conductance),chlorophyll,proline and total sugar contents,and enzyme activities were higher under M2 than under other three mulching treatments.As for irrigation levels,higher values of plant height,photosynthesis and water related parameters(leaf water potential,leaf osmotic potential,leaf turgor potential,etc.)were recorded.Contents of total sugar and proline and activities of antioxidant enzymes were significantly higher in PRD-treated plants than in control plants.It was concluded that combined application of PRD and mulching was more effective than the rest of the treatments used in the experiment.Similar study can be conducted in the field by applying irrigation water in alternate rows in semi-arid regions. | Rashid IQBAL Muhammad A S RAZA Muhammad F SALEEM Imran H KHAN Salman AHMAD Muhammad S ZAHEER Muhammad U ASLAM Imran HAIDER | 2019 | Journal of Arid Land2019，11，5： | 2 |
| 3 | 全视网膜光凝术改善PDR患者的视觉相关生活质量及日常视觉功能(英文)显示文摘目的:评估全视网膜光凝术(PRP)对糖尿病视网膜病变(PDR)患者在视觉相关生活质量及日常视觉功能的影响。方法:研究纳入30例(男13例,女17例)接受全视网膜光凝术治疗糖尿病视网膜病变患者。国家眼科研究所发布的视觉功能量表(VFQ-25)用来评估全视网膜光凝术治疗前后视觉相关生活质量及日常视觉功能。患者在接受全视网膜光凝术治疗前和治疗后6mo分别填写VFQ-25量表,比较视觉相关生活质量及日常视觉功能差异。运用配对t检验对治疗前后VFQ-25评分对比。结果:全视网膜光凝术治疗前平均VFQ-25综合评分为74.79±15.7,术后平均综合评分为74.08±19.1。术前与术后的平均VFQ-25综合评分无统计学意义(P=0.875)。结论:全视网膜光凝术(PRP)对糖尿病视网膜病变(PDR)患者在视觉相关生活质量及日常视觉功能无不利影响。 | Muhammad Imran Saleem Channar Muhammad Farhan Saleem Hafsa Malik | 2016 | 国际眼科杂志2016，16，12： | 2 |
| 4 | Impact of temperature on yield and related traits in cotton genotypes显示文摘Cotton growth and development is influenced by various uncontrollable environmental conditions. Temperature variations in the field can be created by planting at different dates. The objective of the present study was to evaluate the effect of planting dates and thermal temperatures(growing degree days) on yield of 4 cotton genotypes, viz., CIM-598, CIM-599, CIM-602 and Ali Akbar-703. Plants were subjected to 6 planting dates during 2013 and 2014 in a trial conducted in randomized complete block design with four replications. For boll number, boll weight and seed cotton yield, cotton genotypes exhibited significant differences, CIM-599 produced the highest seed cotton yield of 2 062 kg ha^(–1) on account of maximum boll number and boll weight. The highest seed cotton yield was recorded in planting dates from 15 th April to 1st May whereas early and delayed planting reduced the yield due to less accumulation of heat units. Regression analysis revealed that increase of one unit(15 days) from early to optimum date(15th March to 15 th April) increased yield by 93.58 kg ha^(–1). Delay in planting also decreased the seed cotton yield with the same ratio. Thus it is concluded that cotton must be sown from 15 th April to 1st May to have good productivity in this kind of environment. | Kalim Ullah Niamatullah Khan Zahid Usman Rehmat Ullah Fazal Yazdan Saleem Syed Asif Imran Shah Muhammad Salman | 2016 | Journal of Integrative Agriculture2016，15，3： | 1 |
| 5 | Solution-processed,flexible and broadband photodetector based on CsPbBr_(3)/PbSe quantum dot heterostructures显示文摘Due to their promising applications in foldable displays,optical communication equipment and environmental monitoring systems,flexible and broadband optoelectronic devices have gained extensive attention in recent years.Here,a flexible and broadband photodetector based on CsPbBr_(3)/PbSe quantum dot(QD) heterostructures is firstly presented.The integrated QD heterostructures possess consecutive detection range from ultraviolet(UV) to long-wave length infrared(LW-IR) regions with efficient light absorption and chemical stability,in comparison with the pristine PbSe QDs.Systematic material characterizations reveal the improved exciton dissociation,carrier transport and carrier lifetime of the QD heterostructures.Flexible photodetector Ag/CsPbBr_(3)/PbSe/Ag demonstrate a high responsivity of 7.17 A/W with a specific detectivity of 8.97 × 10^(12) Jones under 25 μW/cm^(2) 365 nm illumination at 5 V.Furthermore,it could maintain 91.2 %(or 94.9 %) of its initial performance even after bending for thousands of times(or exposing in ambient air for 4 weeks).More importantly,its re s ponse time is shortened more than three orders of magnitude as that of pristine PbSe QDs-based photodetectors.Therefore,it provides a feasible and promising method for the next-generation high-performance broadband photodetectors via constructing heterostructures of various QDs. | Jinming Hu Shengyi Yang Zhenheng Zhang Hailong Li Chandrasekar Perumal Veeramalai Muhammad Sulaman Muhammad Imran Saleem Yi Tang Yurong Jiang Libin Tang Bingsuo Zou | 2021 | Journal of Materials Science & Technology2021，，9： | 1 |
| 6 | CsPbI nanorods as the interfacial layer for high-performance,all-solution-processed self-powered photodetectors显示文摘Heterojunction is regarded as a crucial step toward realizing high-performance devices,particularly,forming gradient energy band between heterojunctions benefits self-powered photodetectors.Therefore,in this paper,the synthesis of CsPbI3 nanorods(NRs)and its application as the interfacial layer in high-performance,all-solution-processed self-powered photodetectors are presented.For the bilayer photodetector ITO/ZnO(100 nm)/PbS-TBAI(150 nm)/Au,a responsivity of 3.6 A/W with a specific detectivity of 9.8×10^(12)Jones was obtained under 0.1 mW/cm^(2)white light illumination at zero bias(i.e.in self-powered mode).Meanwhile,the photocurrent was enhanced to an On/Off current ratio of 105 at zero bias with an open circuit voltage of 0.53 V for trilayer photodetector ITO/ZnO(100 nm)/PbSTBAI(150 nm)/CsPbI3(250 nm)/Au,in which the CsPbI3 NRs layer works as the interfacial layer.As a result,a specific detectivity of 4.5×10^(13)Jones with a responsivity of 11.12 A/W was obtained under0.1 mW/cm^(2) white light illumination,as well as the rising/decaying time of 0.57 s/0.41 s with excellent stability and reproducibility upto four weeks in air.The enhanced-performance is ascribed to the mismatch bandgap between PbS-TBAI/CsPbI_(3)interface,which can suppress the carrier recombination and provide efficient transport passages for charge carriers.Thus,it provides a feasible and efficient method for high-performance photodetectors. | Muhammad Imran Saleem Shangyi Yang Attia Batool Muhammad Sulaman Chandrasekar Perumal Veeramalai Yurong Jiang Yi Tang Yanyan Cui Libin Tang Bingsuo Zou | 2021 | Journal of Materials Science & Technology2021，，16： | 1 |
| 7 | Traffic Management in Internet of Vehicles Using Improved Ant Colony Optimization显示文摘The Internet of Vehicles(IoV)is a networking paradigm related to the intercommunication of vehicles using a network.In a dynamic network,one of the key challenges in IoV is traffic management under increasing vehicles to avoid congestion.Therefore,optimal path selection to route traffic between the origin and destination is vital.This research proposed a realistic strategy to reduce traffic management service response time by enabling real-time content distribution in IoV systems using heterogeneous network access.Firstly,this work proposed a novel use of the Ant Colony Optimization(ACO)algorithm and formulated the path planning optimization problem as an Integer Linear Program(ILP).This integrates the future estimation metric to predict the future arrivals of the vehicles,searching the optimal routes.Considering the mobile nature of IOV,fuzzy logic is used for congestion level estimation along with the ACO to determine the optimal path.The model results indicate that the suggested scheme outperforms the existing state-of-the-art methods by identifying the shortest and most cost-effective path.Thus,this work strongly supports its use in applications having stringent Quality of Service(QoS)requirements for the vehicles. | Abida Sharif Imran Sharif Muhammad Asim Saleem Muhammad Attique Khan Majed Alhaisoni Marriam Nawaz Abdullah Alqahtani Ye Jin Kim Byoungchol Chang | 2023 | Computers, Materials & Continua2023，，6： | 1 |
| 8 | Context Based Adoption of Ranking and Indexing Measures for Cricket Team Ranks显示文摘There is an international cricket governing body that ranks the expertise of all the cricket playing nations,known as the International Cricket Council(ICC).The ranking system followed by the ICC relies on the winnings and defeats of the teams.The model used by the ICC to implement rankings is deficient in certain key respects.It ignores key factors like winning margin and strength of the opposition.Various measures of the ranking concept are presented in this research.The proposed methods adopt the concepts of h-Index and PageRank for presenting more comprehensive ranking metrics.The proposed approaches not only rank the teams on their losing/winning stats but also take into consideration the margin of winning and the quality of the opposition.Three cricket team ranking techniques are presented i.e.,(1)Cricket Team-Index(ct-index),(2)Cricket Team Rank(CTR)and(3)Weighted Cricket Team Rank(WCTR).The proposed metrics are validated through the collection of cricket dataset,extracted from Cricinfo,having instances for all the three formats of the game i.e.,T20 International(T20i),One Day International(ODI)and Test matches.The comparative analysis between the proposed and existing techniques,for all the three formats,is presented as well. | Raja Sher Afgun Usmani Syed Muhammad Saqlain Shah Muhammad Sher Ramzan Abdullah Saad A.L-Malaise AL-Ghamdi Anwar Ghani Imran Khan Farrukh Saleem | 2020 | Computers, Materials & Continua2020，，11： | 0 |
| 9 | Application of ferrous sulfate alleviates negative impact of cadmium in rice(Oryza sativa L.)显示文摘Soil contamination with toxic heavy metals[such as cadmium(Cd)]is becoming a serious global problem due to rapid development of social economy.Iron(Fe),being an important element,has been found effective in enhancing plant tolerance against biotic and abiotic stresses.The present study investigated the extent to which different levels of Ferrous sulphate(FeSO_(4))modulated the Cd tolerance of rice(Oryza sativa L.),when maintained in artificially Cd spiked regimes.A pot experiment was conducted under controlled conditions for 146 days,by using natural soil,mixed with different levels of CdCl_(2)[0(no Cd),0.5 and 1 mg/kg]together with the exogenous application of FeSO_(4) at[0(no Fe),1.5 and 3 mg/kg]levels to monitor different growth,gaseous exchange characteristics,oxidative stress,antioxidative responses,minerals accumulation,organic acid exudation patterns of O.sativa.Our results depicted that addition of Cd to the soil significantly(P<0.05)decreased plant growth and biomass,gaseous exchange parameters,mineral uptake by the plants,sugars(soluble,reducing,and non-reducing sugar)and altered the ultrastructure of chloroplasts,plastoglobuli,mitochondria,and many other cellular organelles in Cd-stressed O.sativa compared to those plants which were grown without the addition of Cd in the soil.However,Cd toxicity boosted the production of reactive oxygen species(ROS)by increasing the contents of malondialdehyde(MDA),which is the indication of oxidative stress in O.sativa and was also manifested by hydrogen peroxide(H_(2)O_(2))contents and electrolyte leakage to the membrane bounded organelles.Although,activities of various antioxidative enzymes like superoxidase dismutase(SOD),peroxidase(POD),catalase(CAT)and ascorbate peroxidase(APX)and non-enzymatic antioxidants like phenolics,flavonoid,ascorbic acid,anthocyanin and proline contents increased up to a Cd level of 0.5 mg/kg in the soil but were significantly diminished at the highest Cd level of 1 mg/kg in the soil compared to those plants which were grown without the addition of Cd in the soil.The negative impacts of Cd injury were reduced by the application of FeSO_(4) which increased plant growth and biomass,improved photosynthetic apparatus,antioxidant enzymes,minerals uptake together with diminished exudation of organic acids as well as oxidative stress indicators in roots and shoots of O.sativa by decreasing Cd retention in different plant parts.These results shed light on the effectiveness of FeSO_(4) in improving the growth and upregulation of antioxidant enzyme activities of O.sativa in response to Cd stress.However,further studies at field levels are required to explore the mechanisms of FeSO_(4)-mediated reduction of the toxicity of not only Cd,but possibly also other heavy metals in plants. | JAVARIA AFZAL XIUKANG WANG MUHAMMAD HAMZAH SALEEM XUECHENG SUN SHAHID HUSSAIN IMRAN KHAN MUHAMMAD SHOAIB RANA SHAKEEL AHMED SAMRAH AFZAL AWAN SAJID FIAZ OMAR AZIZ KASHIF ALI KUBAR SHAFAQAT ALI CHENGXIAO HU | 2021 | BIOCELL2021，45，6： | 0 |
| 10 | 没有为 tractional 的 endotamponade 的同等 plana vitrectomy 的结果对 proliferative 糖尿病患者 retinopathy 第二等的网膜的分开显示文摘AIM:To evaluate the outcomes of pars plana vitrectomy(PPV) without the use of an ocular tamponade in patients having tractional retinal detachment(TRD) secondary to proliferative diabetic retinopathy(PDR).METHODS:It was an interventional study conducted at the Department of Ophthalmology,B.V.Hospital,Bahawalpur,Pakistan,from July 2011 to July 2012.A total of 75 patients(84 eyes) having TRD secondary to PDR were treated by PPV without using an ocular tamponade.All patients included in the study had a tractional retinal detachement secondary to proliferative diabetic retinopathy but didn’t have or develop retinal breaks before or during the study period.The surgical procedure included a PPV combined with the removal of the tractional retinal membranes and the application of endolaser photocoagulation to the retina.The mean follow-up period was 12 months. RESULTS:Successful retinal reattachement was observed in 78 of the operated eyes(92.8%).In these patients,the retina remained attached till the end of the one year follow-up period.Improvement in best corrected visual acuity(BCVA) was seen in 63 eyes(75%).The visual acuity remained unchanged in 9 eyes(10.7%).Mean improvement in BCVA was 2.00 +1.24 at baseline to 1.24+1.22(P<0.05) at the end of the followup period.CONCLUSION:In the absence of the retinal breaks,a TRD secondary to PDR can be successfully treated by pars plana vitrectomy without the use of an ocular tamponade. | Rao Muhammad Rashad Qamar Muhammad Imran Saleem Muhammad Farhan Saleem | 2013 | International Journal of Ophthalmology(English edition)2013，6，5： | 0 |
| 11 | From Molecular Pathology of COVID-19 to Nigella Sativum as a Treatment Option:Scientific Based Evidence of Its Myth or Reality显示文摘COVID-19 virus is a causative agent of viral pandemic in human beings which specifically targets respiratory system of humans and causes viral pneumonia.This unusual viral pneumonia is rapidly spreading to all parts of the world,currently affecting about 105 million people with 2.3 million deaths.Current review described history,genomic characteristics,replication,and pathogenesis of COVID-19 with special emphasis on Nigella sativum(N.sativum)as a treatment option.N.sativum seeds are historically and religiously used over the centuries,both for prevention and treatment of different diseases.This review summarizes the potential role of N.sativum seeds against COVID-19 infection at levels of in silico,cell lines and animal models. | Muhammad Atif Farrah Naz Junaid Akhtar Muhammad Imran Sidrah Saleem Javed Akram Muhammad Imran Muhammad Ikram Ullah | 2022 | Chinese Journal of Integrative Medicine2022，28，1： | 0 |
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