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| 1 | Involvement of C2H2 zinc finger proteins in the regulation of epidermal cell fate determination in Arabidopsis显示文摘Cell fate determination is a basic developmental process during the growth of multicellular organisms.Trichomes and root hairs of Arabidopsis are both readily accessible structures originating from the epidermal cells of the aerial tissues and roots respectively, and they serve as excellent models for understanding the molecular mechanisms controlling cell fate determination and cell morphogenesis. The regulation of trichome and root hair formationis a complex program that consists of the integration of hormonal signals with a large number of transcriptional factors, including MYB and b HLH transcriptional factors.Studies during recent years have uncovered an important role of C2H2 type zinc finger proteins in the regulation of epidermal cell fate determination. Here in this minireview we briefly summarize the involvement of C2H2 zinc finger proteins in the control of trichome and root hair formation in Arabidopsis. | An Yan Minjie Wu Yongqin Zhao Aidong Zhang Bohan Liu John Schiefelbein Yinbo Gan | 2014 | Journal of Integrative Plant Biology2014，56，12： | 7 |
| 2 | All in one theranostic nanoplatform enables efficient anti-tumor peptide I delivery for triple-modal imaging guided cancer therapy显示文摘Developing a reliable system to efficiently and safely deliver peptide drugs into tumor tissues still remains a great challenge since the instability of peptide drugs and low ability to traverse the cell membrane. Herein, we constructed a multifunctional nanoplatform based on porous europium/gadolinium (Eu/Gd)-doped NaLa(MoO4)2 nanoparticles (NLM NPs) to deliver antitumor peptide of B-cell lymphoma/leukemia-2-like protein 11 (BIM) for cancer therapy. The porous NLM NPs exhibited inherent photoluminescent, magnetic and X-ray absorbable properties, which enable them for triple-modal bioimaging, including fluorescence, magnetic resonance imaging (MRI) and computed tomography (CT). This triple-modal bioimaging can contribute to monitoring NLM NPs biodistribution and guiding therapy in vitro and in vivo. Furthermore, the NLM NPs showed negligible cytotoxicity in vitro and tissue toxicity in vivo. Importantly, NLM NPs could load the antitumor peptide of BIM and efficiently improve the resistance of peptide drugs to proteolysis. The BIM peptide was efficiently delivered into the tumor cells by NLM NPs, which can inhibit the growth and promote the apoptosis of cancer cells in vitro, significantly inhibit the tumor growth in vivo. Notably, NLM-BIM theranostic nanoplatform exhibits low systemic toxicity and fewer side effects in vivo. The NLM NPs can serve as a promising multifunctional peptide delivery nanoplatform for multi-modal bioimaging and cancer therapy. | Xiaoyan Qu Zhengqing Liu Bohan Ma Na Li Hongyang Zhao Tian Yang Yumeng Xue Xiaozhi Zhang Yongping Shao Ying Chang Jun Xu Bo Lei Yaping Du | 2019 | Nano Research2019，12，3： | 2 |
| 3 | Ultra-strong phosphorescence with 48% quantum yield from grinding treated thermal annealed carbon dots and boric acid composite显示文摘Metal-free room-temperature phosphorescence(RTP)materials are of great significance for many applications;however,they usually exhibit low efficiency and weak intensity.This article reports a new strategy for the preparation of a high-efficiency and strong RTP materials from crystalline thermal-annealed carbon dots(CDs)and boric acid(BA)composite(g-t-CD@BA)through grinding-induced amorphous to crystallization transition.Amorphous thermal-annealed CDs and BA composite(t-CD@BA)is prepared following a thermal melting and super-cooling route,where the CDs are fully dispersed in molten BA liquid and uniformly frozen in an amorphous thermal annealed BA matrix after super-cooling to room temperature.Upon grinding treatment,the fracture and fragmentation caused by grinding promote the transformation of the high-energy amorphous state to the lower energy crystalline counterparts.As a result,the CDs are uniformly in situ embedded in the BA crystal matrix.This method affords maximum uniform embedding of the CDs in the BA crystals,decreases nonradiative decay,and promotes intersystem crossing by restraining the free vibration of the CDs,thus producing strong RTP materials with the highest reported phosphorescence quantum yield(48%).Remarkably,RTP from g-t-CD@BA powder is strong enough to illuminate items with a delay time exceeding 9 s. | Qijun Li Zhenxiao Zhao Shuai Meng Yuchen Li Yunyang Zhao Bohan Zhang Zikang Tang Jing Tan Songnan Qu | 2022 | SmartMat2022，3，2： | 2 |
| 4 | Acidic deposition and its effects in southwestern China显示文摘 | Hans M. Skip Zhao Dianwu Xiong Tiling Zhao Dawei Thorj?rn Larssen Liao Bohan Rolf D. Vogt | 1995 | Water Air & Soil Pollution1995，，4： | 1 |
| 5 | Long-range gene regulation network of the MGMT enhancer modulates glioma cell sensitivity to temozolomide显示文摘Approximately 80%of primary tumors in the central nervous system are malignant glioma,and>50%of those are diagnosed as glioblastoma(GBM),the most aggressive glioma.Despite treatment advances,GBM prognosis is unsatisfying,and the median survival time of patients is only 14-17 months. | Bohan Chen Anshun He Jinfang Bi Shupeng Sun Yiping Ma Wenbin Wang Dianhao Guo Jun Chen Yuyang Qian Tengfei Shi Guohui Nie Zhongfang Zhao Jiandang Shi Hongzhen Yang Lei Zhang Wange Lu | 2021 | Journal of Genetics and Genomics2021，48，10： | 1 |
| 6 | Acidic deposition and its effects in southwestern China显示文摘 | Hans M. Skip Zhao Dianwu Xiong Tiling Zhao Dawei Thorj?rn Larssen Liao Bohan Rolf D. Vogt | 1995 | Water Air & Soil Pollution1995，，4： | 1 |
| 7 | Rationally designed Fe-MCM-41 by protein size to enhance lipase immobiliza- tion, catalytic efficiency and performance 显示文摘 | Lin Jiafu Zhao Bohan Cao Yu | 2014 | Appl Catal A: General2014，478，： | 1 |
| 8 | Exclusion and Co-expression of Aversive Olfactory Long-Term Memories in Drosophila显示文摘Long-term memory(LTM)allows animals to use remote past experiences to guide current and future decisions.One of the widely-used animal models for LTM research is the fruit-fly Drosophila melanogaster,which can form different types of LTM after different learning paradigms[1-6].Spaced training-induced LTM(spLTM),perhaps the most studied Drosophila LTM,requires multiple repeated learning trials with a 15-min resting interval between each trial.For decades,spLTM has been considered the only aversive olfactory LTM that can last for>7 days[1].Recently,two other types of LTM,context-dependent LTM(cLTM)[5]and merged LTM(mLTM)[6],have been discovered with the same long duration as spLTM,and can be formed with only one aversive learning trial. | Bohan Zhao Xuchen Zhang Janjan Zhao Qian Li | 2022 | Neuroscience Bulletin2022，38，6： | 0 |
| 9 | Self-Assembled Porous-Reinforcement Microstructure-Based Flexible Triboelectric Patch for Remote Healthcare显示文摘Realizing real-time monitoring of physiological signals is vital for preventing and treating chronic diseases in elderly individuals. However,wearable sensors with low power consumption and high sensitivity to both weak physiological signals and large mechanical stimuli remain challenges.Here, a flexible triboelectric patch(FTEP) based on porous-reinforcement microstructures for remote health monitoring has been reported. The porousreinforcement microstructure is constructed by the self-assembly of silicone rubber adhering to the porous framework of the PU sponge. The mechanical properties of the FTEP can be regulated by the concentrations of silicone rubber dilution. For pressure sensing, its sensitivity can be effectively improved fivefold compared to the device with a solid dielectric layer, reaching 5.93 kPa^(-1) under a pressure range of 0–5 kPa. In addition, the FTEP has a wide detection range up to 50 kPa with a sensitivity of 0.21 kPa^(-1). The porous microstructure makes the FTEP ultra-sensitive to external pressure, and the reinforcements endow the device with a greater deformation limit in a wide detection range. Finally, a novel concept of the wearable Internet of Healthcare(Io H) system for real-time physiological signal monitoring has been proposed, which could provide real-time physiological information for ambulatory personalized healthcare monitoring. | Hao Lei Haifeng Ji Xiaohan Liu Bohan Lu Linjie Xie Eng Gee Lim Xin Tu Yina Liu Peixuan Zhang Chun Zhao Xuhui Sun Zhen Wen | 2023 | Nano-Micro Letters2023，15，7： | 0 |
| 10 | Plastic Crystal Neopentyl Glycol/Multiwall Carbon Nanotubes Composites for Highly Efficient Barocaloric Refrigeration System显示文摘Plastic crystal neopentyl glycol(NPG)exhibits colossal barocaloric effect with high entropy changes.However,their application is restricted in several aspects,such as low thermal conductivity,substantial supercooling effect,and poor springback properties.In this work,multi-walled carbon nanotubes(MWCNTs)with ultra-high thermal conductivity and high mechanical strength were selected for performance enhancement of NPG.The optimal mixing ratio was determined to be NPG with 3 wt%MWCNTs composites,which showed a 6K reduction in supercooling without affecting the phase change enthalpy.Subsequently,comprehensive performance of the composites with optimal mixing ratio was compared with pure NPG At 40 MPa,390J·K^(-1)·kg^(-1)change in entropy and 9.9 K change in temperature were observed.Furthermore,the minimum driving pressure required to achieve reversible barocaloric effect was reduced by 19.2%.In addition,the thermal conductivity of the composite was increased by approximately 28%,significantly reducing the heat exchange time during a barocaloric refrigeration cycle.More importantly,ultra-high pressure release rate resulted in a73.7%reduction in the springback time of the composites,offering new opportunities for the recovery of expansion work. | DAI Zhaofeng SHE Xiaohui SHAO Bohan YIN Ershuai DING Yulong LI Yongliang ZHANG Xiaosong ZHAO Dongliang | 2024 | Journal of Thermal Science2024，33，1： | 0 |
| 11 | New genetic and epigenetic insights into the chemokine system: the latest discoveries aiding progression toward precision medicine显示文摘Over the past thirty years,the importance of chemokines and their seven-transmembrane G protein-coupled receptors(GPCRs)has been increasingly recognized.Chemokine interactions with receptors trigger signaling pathway activity to form a network fundamental to diverse immune processes,including host homeostasis and responses to disease.Genetic and nongenetic regulation of both the expression and structure of chemokines and receptors conveys chemokine functional heterogeneity.Imbalances and defects in the system contribute to the pathogenesis of a variety of diseases,including cancer,immune and inflammatory diseases,and metabolic and neurological disorders,which render the system a focus of studies aiming to discover therapies and important biomarkers.The integrated view of chemokine biology underpinning divergence and plasticity has provided insights into immune dysfunction in disease states,including,among others,coronavirus disease 2019(COVID-19).In this review,by reporting the latest advances in chemokine biology and results fromanalyses of a plethora of sequencing-based datasets,we outline recent advances in the understanding of the genetic variations and nongenetic heterogeneity of chemokines and receptors and provide an updated view of their contribution to the pathophysiological network,focusing on chemokine-mediated inflammation and cancer.Clarification of the molecular basis of dynamic chemokine-receptor interactions will help advance the understanding of chemokine biology to achieve precision medicine application in the clinic. | Hanli Xu Shuye Lin Ziyun Zhou Duoduo Li Xiting Zhang Muhan Yu Ruoyi Zhao Yiheng Wang Junru Qian Xinyi Li Bohan Li Chuhan Wei Keqiang Chen Teizo Yoshimura Ji Ming Wang Jiaqiang Huang | 2023 | Cellular & Molecular Immunology2023，20，7： | 0 |
| 12 | Morphology and Molecular Phylogeny of Two Marine Folliculinid Ciliates Found in China (Ciliophora, Heterotrichea)显示文摘Ciliates of the heterotrich family Folliculinidae are characterized by their transparent lorica,conspicuous peristomial lobes pair and dimorphic life cycle,a sessile trophont and a motile swarmer.However,understanding their biodiversity and systematics is relatively poor.In the present study,two species representing two genera of folliculinids,which were collected from marine and brackish habitats in China,were investigated with morphological and molecular methods.The genus Diafolliculina n.gen.is established for D.longilobata n.sp.Detailed morphological redescriptions for another species Eufolliculina is provided.Moreover,phylogenetic analysis based on small subunit ribosomal DNA(SSU rDNA)sequences showed that 1)all two genera locate in the Folliculinidae clade;2)Metafolliculina clusters with Eufolliculina;and 3)two genera(Diafolliculina and Ampullofolliculina)with a lorica closure device have close affinities with Folliculina.The lorica of Diafolliculina and Ampullofolliculina lacks a closure device,thereby the phylogeney contradicts the morphology-based classification. | YE Tingting ZHAO Xuetong CHI Yong ZHENG Bohan ZHANG Hui HUANG Jie WARREN Alan CHEN Xiangrui | 2021 | Journal of Ocean University of China2021，20，4： | 0 |
| 13 | Diffusion effect on the decay of time-resolved photoluminescence under low illumination in lead halide perovskites显示文摘Time-resolved photoluminescence(TRPL)has been extensively used to measure the carrier lifetime in lead halide perovskites.The TRPL curves of perovskite materials are usually fitted with a multi-exponential function,instead of a single exponential one.This was considered to be a result of the surface and the bulk recombination or the additional radiative recombination caused by the high excited carrier density.Here,a new model considering the diffusion and the trap-assisted recombination of carriers is proposed to explain the TRPL curves.The expressions of the TRPL curves and the transient absorption(TA)dynamic curves are theoretically derived,demonstrating that the TRPL curve is an infinite exponential series,regardless of the presence of surface recombination or not.Our newly developed highly sensitive nanosecond TA and TRPL were employed to measure the carrier dynamics of the same sample under low illumination in the linear response region of TA,thereby experimentally verifying our model.These results suggest that the decay of the TRPL is not only a consequence of the carrier recombination but also the carrier diffusion.TRPL cannot provide a direct measurement of the carrier lifetime,whereas TA spectroscopy can.Furthermore,the surface and the bulk recombination can be resolved and the average diffusion coefficient(D)can also be correctly obtained by combining TRPL and TA measurements.We also propose an approximate method for calculating the carrier lifetime and diffusion coefficient of high-quality perovskite films.Our model provides not only a new interpretation of the dynamics of the PL decay but also a deep insight into the carrier dynamics in the nanosecond time scale under working condition of perovskites solar cells. | Huang Li Haipeng Di Xingan Wang Zefeng Ren Ming Lu An-An Liu Xueming Yang Nanlin Wang Yiying Zhao Bohan Li | 2023 | Science China(Physics,Mechanics & Astronomy)2023，66，8： | 0 |
| 14 | Metal-Oxo Cluster Catalysts for Photocatalytic Water Splitting and Carbon Dioxide Reduction显示文摘Photocatalytic water splitting and carbon dioxide photoreduction are considered eff ective strategies for alleviating the energy crisis and environmental pollution.Polynuclear metal-oxo clusters possess excellent electron storage/release ability and unique catalytic properties via intermetallic synergy,which enables them with great potential in environmentally friendly photosynthesis.Importantly,metal-oxo clusters with precise structure can not only act as high-effi ciency catalysts but also provide well-defi ned structural models for exploring structure-activity relationships.In this review,we systematically sum-marize recent progress in the catalytic application of polynuclear metal-oxo clusters,including polyoxometalate clusters,low-cost transition metal clusters,and metal-oxo-cluster-based metal-organic frameworks for water splitting and CO_(2)reduction.Furthermore,we discuss the challenges and solutions to the problems of polynuclear metal-oxo clusters in photocatalysis. | Qing Lan Sujuan Jin Bohan Yang Qiang Zhao Chaolei Si Haiquan Xie Zhiming Zhang | 2022 | Transactions of Tianjin University2022，28，3： | 0 |
| 15 | g-C_(3)N_(4) templated mesoporous carbon with abundant heteroatoms as high-rate anode material for dual-carbon sodium ion hybrid capacitors显示文摘Sodium ion hybrid capacitors(SIHCs)are regarded as advanced power supply systems.Nevertheless,the kinetics imbalance of cathode and anode suppresses the further performance improvement of SIHCs.The carbonaceous anode materials are promising and many strategies have been utilized to increase the capacity of sloping region or accelerate the reaction rate of plateau region.However,it is still challenging to simultaneously realize high mesopore/micropore volume ratio,large interlayer distance(>0.37 nm),and abundant and favorable heteroatoms-doping by a simple method.Herein,we report N,P,O ternarydoped mesoporous carbon(PNPOC-T,T=700,800 or 900)with large interlayer distance(~0.4 nm)as anode materials.The PNPOC-T were prepared by a simple in-situ polymerization of aniline and phytic acid on the exfoliated graphitic nitrogen carbide(g-C3N4)and subsequent carbonization.The obtained PNPOC-800 exhibits an excellent rate performance(101.5 mA·h·g^(-1) at 20 A·g^(-1)),which can be attributed to the high surface-controlled capacitive behavior ratio and rapid ion diffusion.The optimum SIHCs display a high energy density of 105.48 W·h·kg^(-1) and a high power density of 13.59 kW$kg1.Furthermore,the capacitance retention rate of SIHCs can reach 87.43%after 9000 cycles at 1 A·g^(-1). | Chong Wang Qingtao Yu Ning Zhao Bohan Li Wanci Shen Feiyu Kang Zheng-Hong Huang Ruitao Lv | 2022 | Journal of Materiomics2022，8，6： | 0 |
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