|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Accuracy of magnetic resonance cholangiography compared to operative endoscopy in detecting biliary stones, a single center experience and review of literature显示文摘AIM: To compare diagnostic sensitivity, specificity and accuracy of magnetic resonance cholangiopancreatography(MRCP) without contrast medium and endoscopic ultrasound(EUS)/endoscopic retrograde cholangiopancreatography(ERCP) for biliary calculi. METHODS: From January 2012 to December 2013, two-hundred-sixty-three patients underwent MRCP at our institution, all MRCP procedure were performed with the same machinery. In two-hundred MRCP was done for pure hepatobiliary symptoms and these patients are the subjects of this study. Among these two-hundred patients, one-hundred-eleven(55.5%) underwent ERCP after MRCP. The retrospective study design consisted in the systematic revision of all images from MRCP and EUS/ERCP performed by two radiologist with a long experience in biliary imaging, an experienced endoscopist and a senior consultant in Hepatobiliopancreatic surgery. A false positive was defined an MRCP showing calculi with no findings at EUS/ERCP; a true positive was defined as a concordance between MRCP and EUS/ERCP findings; a false negative was defined as the absence of images suggesting calculi at MRCP with calculi localization/extraction at EUS/ERCP and a true negative was defined as a patient with nocalculi at MRCP ad at least 6 mo of asymptomatic followup. Biliary tree dilatation was defined as a common bile duct diameter larger than 6 mm in a patient who had an in situ gallbladder. A third blinded radiologist who examined the MRCP and ERCP data reviewed misdiagnosed cases. Once obtained overall data on sensitivity, specificity, accuracy, positive predictive value(PPV) and negative predictive value(NPV) we divided patients in two groups composed of those having concordant MRCP and EUS/ERCP(Group A, 72 patients) and those having discordant MRCP and EUS/ERCP(Group B, 20 patients). Dataset comparisons had been made by the Student's t-test and χ2 when appropriate.RESULTS: Two-hundred patients(91 men, 109 women, mean age 67.6 years, and range 25-98 years) underwent MRCP. All patients attended regular follow-up for at least 6 mo. Morbidity and mortality related to MRCP were null. MRCP was the only exam performed in 89 patients because it did show only calculi into the gallbladder with no signs of the presence of calculi into the bile duct and symptoms resolved within a few days or after colecistectomy. The patients remained asymptomatic for at least 6 mo, and we assumed they were true negatives. One hundred eleven(53 men, 58 women, mean age 69 years, range 25-98 years) underwent ERCP following MRCP. We did not find any difference between the two groups in terms of race, age, and sex. The overall median interval between MRCP and ERCP was 9 d. In detecting biliary stones MRCP Sensitivity was 77.4%, Specificity 100% and Accuracy 80.5% with a PPV of 100% and NPV of 85%; EUS showed 95% sensitivity, 100% specificity, 95.5% accuracy with 100% PPV and 57.1% NPV. The association of EUS with ERCP performed at 100% in all the evaluated parameters. When comparing the two groups, we did not find any statistically significant difference regarding age, sex, and race. Similarly, we did not find any differences regarding the number of extracted stones: 116 stones in Group A(median 2, range 1 to 9) and 27 in Group B(median 2, range 1 to 4). When we compared the size of the extracted stones we found that the patients in Group B had significantly smaller stones: 14.16 ± 8.11 mm in Group A and 5.15 ± 2.09 mm in Group B; 95% confidence interval = 5.89-12.13, standard error = 1.577; P < 0.05. We also found that in Group B there was a significantly higher incidence of stones smaller than 5 mm: 36 in Group A and 18 in Group B, P < 0.05.CONCLUSION: Major finding of the present study is that choledocholithiasis is still under-diagnosed in MRCP. Smaller stones(< 5 mm diameter) are hardly visualized on MRCP. | Francesco A Polistina Mauro Frego Marco Bisello Emy Manzi Antonella Vardanega Bortolo Perin | 2015 | World Journal of Radiology2015，7，4： | 14 |
| 2 | Endogenous parathyroid hormone-related protein regulates the expression of PTH type 1 receptor and proliferation of vascular smooth muscle cells显示文摘 | Song G J Fiaschi-Taesch N Bisello A | 2009 | Mol Endocrinol2009，23，10： | 1 |
| 3 | A comparison of parathyroid hormone‐related protein (1‐36) and parathyroid hormone (1‐34) on markers of bone turnover and bone density in postmenopausal women: The PrOP study显示文摘 | Mara J Horwitz Marilyn Augustine Leila Kahn Emily Martin Christine C Oakley Raquel M Carneiro Mary Beth Tedesco Angela Laslavic Susan M Sereika Alessandro Bisello Adolfo Garcia‐Oca?a Caren M Gundberg Jane A Cauley Andrew F Stewart | 2013 | J Bone Miner Res2013，，11： | 1 |
| 4 | Activation-independent parathyroid hormone receptor internalization is regulated by NHERF1 (EBP50) 显示文摘 | Sneddon WB Syme CA Bisello A | 2003 | J Biol Chem2003，278，43： | 1 |
| 5 | Endogenous parathyroid hormone-related protein regulates the expression of PTH type 1 receptor and proliferation of vascular smooth muscle cells显示文摘 | Song GJ Fiaschi-Taesch N Bisello A | 2009 | Mol Endocrinol2009，23，： | 1 |
| 6 | Development of po- tent glucagon-like peptide-1 aganists with high enzyme stability via introduction of multiple lactam bridge 显示文摘 | MURAGE EN GAO G BISELLO A | 2010 | J Meal Chem2010，53，17： | 1 |
| 7 | Parathyroid hormone-related protein:an essential physiological regulator of adult bone mass显示文摘 | Bisello A Horwitz MJ Stewart AF | 2004 | Endocrinology2004，145，8： | 1 |
| 8 | Role of Transarterial Chemoembolization Before Liver Resection for Hepatocarcinoma显示文摘 | Giorgio Enrico Gerunda Daniele Neri Roberto Merenda Franco Barbazza Fabio Zangrandi Francesco Meduri Marco Bisello Michele Valmasoni Antonio Gangemi Alvise Maffei Faccioli | 2000 | Liver Transplantation2000，，5： | 1 |
| 9 | Devetopnmnt of potent glucagon-like peptide-1 aganists with high enzyme stability via introduction of muhiple lactam bridge显示文摘 | Murage E N Gao G Bisello A | 2010 | J Med Chem2010，53，17： | 1 |
| 10 | Selective ligandinduced stabilization of active and desensitized parathyroid hormone type 1 receptor conformations 显示文摘 | Bisello A Chorev M Rosenblatt M | 2002 | J Biol Chem2002，277，38： | 1 |
| 11 | Measurement of the e + e ? → π + π ? π 0 and e + e ? → ωπ + π ? reactions in the energy interval 1350–2400 MeV显示文摘 | A. Antonelli R. Baldini M. E. Biagini S. Calcaterra M. Schioppa D. Bisello G. Busetto A. Castro M. Nigro L. Pescara P. Sartori L. Stanco J. E. Augustin L. Ayach G. Cosme F. Couchot F. Fulda G. Grosdidier B. Jean-Marie V. Lepeltier G. Szklarz | 1992 | Zeitschrift für Physik C Particles and Fields1992，，1： | 1 |
| 12 | Comparison of radiation degradation induced by x-ray and 3-MeV protons in 65-nm CMOS transistors显示文摘The total ionizing dose(TID) response of 65-nm CMOS transistors is studied by 10-ke V x-ray and 3-Me V protons up to 1 Grad(SiO_2) total dose.The degradation levels induced by the two radiation sources are different to some extent.The main reason is the interface dose enhancement due to the thin gate oxide and the low energy photons.The holes' recombination also contributes to the difference.Compared to these two mechanisms,the influence of the dose rate is negligible. | 丁李利 Simone Gerardin Marta Bagatin Dario Bisello Serena Mattiazzo Alessandro Paccagnella | 2016 | Chinese Physics B2016，25，9： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员