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| 1 | 探讨健康足月新生儿NBNA的影响因素显示文摘目的分析胎龄、日龄、体重及性别对健康足月新生儿行为神经测定(NBNA)的影响,并与常模数据进行比较,探讨NBNA的理想值范围。方法选择2009年11月至2012年6月河北省三河市妇幼保健院出生的健康足月儿,生后1周内行NBNA测定,对得分情况进行统计学描述,对不同胎龄、检查日龄、体重及性别之间NBNA总分的差异应用秩和检验,探讨NBNA总分的影响因素。并且对比分析本项目与1988年中国12城市健康新生儿NBNA评分的差异。结果共入选1345例健康足月新生儿,NBNA总分均在37分以上,平均(39.6±0.7)分。扣分项目主要出现在对光习惯的形成、对声音习惯的形成、握持反射及牵拉反应4个单项中,以牵拉反应扣分最多。不同胎龄、日龄、体重及不同性别之间NBNA总分差异无统计学意义(P>0.05)。但随胎龄增加,NBNA满分率有增加趋势。与1988年中国12城市健康新生儿NBNA评分结果进行比较,NBNA得分分布有显著差异,本项目得分无37分以下者,且39分及40分所占比例更高。结论 NBNA作为一种足月新生儿的行为神经评估方法,在健康足月儿中总分的分布不受性别、日龄及体重的影响,但NBNA评分的满分率存在随胎龄增加而增加的趋势。将生后7天以内新生儿NBNA总分35~36分视为正常须谨慎,足月新生儿NBNA评估中理想得分为37分以上。 | 卓秀伟 李明 边旸 Betsy Lozoff | 2013 | 中国新生儿科杂志2013，28，4： | 12 |
| 2 | 生命早期不同时期铁缺乏对儿童运动发育影响的纵向研究显示文摘目的明确生命早期不同时期铁缺乏对儿童运动发育的影响。方法纵向研究,共纳入114名出生于2010年4月至2011年12月的杭州市富阳区儿童(男58名、女56名)。基于脐血和9月龄铁营养状况测定,分为出生前铁缺乏组(34名)、出生后铁缺乏组(37名)、铁充足组(43名)。对114名儿童在9月龄、18月龄和5周岁时分别采用Peabody运动发育量表和BOT2-简版评估运动能力;利用多层线性模型纵向分析儿童随年龄的运动发育趋势及不同时期铁缺乏对儿童运动发育的影响,并调整相关混杂因素后分析不同时期铁缺乏儿童在不同受教育程度家庭环境下的运动发展差异。结果 9月龄、18月龄、5周岁时参与运动发育评估的儿童分别为107、109和114名;进行多种混杂因素控制后,出生前铁缺乏组儿童的运动评分低于铁充足组儿童,差异有统计学意义(52.04比54.05分,β=-2.01,P=0.007);出生后铁缺乏组儿童的运动评分(53.07分)与铁充足组儿童差异无统计学意义(β=-0.98,P=0.180)。无论母亲受教育程度高低,出生前铁缺乏组儿童的运动评分均低于铁充足组儿童(49.86比52.15分,49.58比51.58分,β=-2.29、-2.00,P=0.031、0.049)。在铁充足组儿童中,母亲受教育程度较高的儿童运动评分更高(52.45比50.46分,β=1.99,P=0.035)。结论出生前铁缺乏儿童的运动发育不能随年龄增长追赶上铁充足儿童,提示预防母亲孕期缺铁的重要性。 | 章逸莉 郑双双 朱柳燕 季钗 Rosa M Angulo-Barroso Betsy Lozoff 邵洁 | 2019 | 中华儿科杂志2019，57，3： | 11 |
| 3 | Classification of Subtype of Acute Ischemic Stroke: Definitions for Use in a Multicenter Clinical Trial显示文摘 | Harold P. Adams Birgitte H. Bendixen L. Jaap Kappelle José Biller Betsy B. Love David Lee Gordon E. Eugene Marsh | 1993 | Stroke1993，，1： | 9 |
| 4 | Annual report to the nation on the status of cancer, 1975‐2006, featuring colorectal cancer trends and impact of interventions (risk factors, screening, and treatment) to reduce future rates显示文摘 | Brenda K.Edwards ElizabethWard Betsy A.Kohler ChristieEheman Ann G.Zauber Robert N.Anderson AhmedinJemal Maria J.Schymura IrisLansdorp‐Vogelaar Laura C.Seeff Marjoleinvan Ballegooijen S. LuukGoede Lynn A. G.Ries | 2010 | Cancer2010，，3： | 6 |
| 5 | 气候与人类起源显示文摘当环境学家准备在本周会聚在里约热内卢考虑未来的全球气候的时候,地球科学家正处在深刻的变革之中。这就是过去全球气候到底是如何变化的,以及这些变化究竟如何影响人类生存的。研究者已经开始把那些地质上和天文上的力量融合在一起形成一种明显的图像,这些力量被认为是过去数亿年期间地球环境由热到冷、由湿到干而后再相反变化的主要力量。 | William F.Allman Betsy Wagner 梁文举 孙玉芳 | 1993 | 世界科学1993，，5： | 3 |
| 6 | Anastomotic Leaks After Intestinal Anastomosis: It?s Later Than You Think显示文摘 | Neil Hyman Thomas L. Manchester Turner Osler Betsy Burns Peter A. Cataldo | 2007 | Annals of Surgery2007，，2： | 2 |
| 7 | Classification of Subtype of Acute Ischemic Stroke: Definitions for Use in a Multicenter Clinical Trial显示文摘 | Harold P. Adams Birgitte H. Bendixen L. Jaap Kappelle José Biller Betsy B. Love David Lee Gordon E. Eugene Marsh | 1993 | Stroke1993，，1： | 2 |
| 8 | Toward guided tissue and bone regeneration: morphology, attachment, proliferation, and migration of cells cultured on collagen barrier membranes. A systematic review显示文摘 | Jan Behring Rüdiger Junker X. Frank Walboomers Betsy Chessnut John A. Jansen | 2008 | Odontology2008，，1： | 1 |
| 9 | Epidermal growth factor receptor expression and measurement in solid tumors显示文摘 | David C. Spaulding Betsy O. Spaulding | 2002 | Seminars in Oncology2002，，5： | 1 |
| 10 | Anastomotic leakage following anterior resection for rectal cancer显示文摘 | I. Kanellos K. Vasiliadis S. Angelopoulos T. Tsachalis M. G. Pramateftakis I. Mantzoros D. Betsis | 2004 | Techniques in Coloproctology2004，，1： | 1 |
| 11 | Hand in Hand:Museums and libraries working together 显示文摘 | Betsy D Sherman D | 2003 | Public Libraries2003，42，2： | 1 |
| 12 | Caspofungin for the treatment of fungal infections : a systematic review of randomized controlled trials 显示文摘 | Falagas ME Ntziora F Betsi GI | 2007 | Int J Antimicrob Agents2007，29，2： | 1 |
| 13 | Clarifying the concept of criti-cal thinking in nursing显示文摘 | Betsy SP Gloria M | 1993 | The Journal of NursingEducation1993，32，9： | 1 |
| 14 | Role of glycogen synthase kinase-3 in insulin resistance and type2 diabetes显示文摘 | Henriksen Erik J Dokken Betsy B | 2006 | Current Drug Targets2006，7，11： | 1 |
| 15 | Hand in hand:museums and libraries working together显示文摘 | Betsy D Sherman D | 2003 | Public Libraries2003，42，2： | 1 |
| 16 | Tackling Copyright in the Digital Age:An Initiative of the University of Connecticut Libraries显示文摘 | Barbara O Betsy P Rudnick T E | 2008 | Journal of Access Services2008，，： | 1 |
| 17 | Annual Report to the Nation on the status of cancer, 1975‐2008, featuring cancers associated with excess weight and lack of sufficient physical activity显示文摘 | ChristieEheman S. JaneHenley RachelBallard‐Barbash Eric J.Jacobs Maria J.Schymura Anne‐MichelleNoone LipingPan Robert N.Anderson Janet E.Fulton Betsy A.Kohler AhmedinJemal ElizabethWard MarcusPlescia Lynn A. G.Ries Brenda K.Edwards | 2012 | Cancer2012，，9： | 1 |
| 18 | Water quality impacts of small-scale hydromodification in an urban stream in Connecticut, USA显示文摘Introduction:Construction activities in and along urban streams increase the sediment input into surface waters,causing an overall decline in water quality and aquatic ecosystems.In this case study,we investigate the water quality impacts of local hydromodification in an urban stream(discharge 0.4 m^(3)/s).At the site of interest,workers removed a stream crossing consisting of an embankment with culverts and replaced it with a small bridge(single span of 25 m)in an effort to improve flow capacity.Methods:Water samples were taken at four sites along the North Branch Park River in Connecticut,Northeastern United States.Turbidity and dissolved oxygen(DO)were measured in situ,and nitrate and total phosphorus(TP)were measured in the laboratory.Benthic macroinvertebrate samples were also collected and analyzed for taxon richness and Shannon-Weaver species diversity.Data were compared between upstream and downstream sites and before,during,and after hydromodification.We used one-way ANOVA combined with the post hoc Turkey test to derive statistical significance.Results:During construction,turbidity increased temporarily by 60.9%[from 2.48 Nephelometric Turbidity Units(NTU)over ambient to 4.00 NTU].Once construction was completed,DO increased locally from 11.0 to 13.0 mg/L.Benthic macroinvertebrate taxon richness and species diversity declined by 61.6 and 32.6%respectively,with no recovery observed in the year following construction.Water quality was only affected within 50 m downstream.Nitrate and TP concentrations were unaffected.Conclusions:Small-scale hydromodification temporarily increased the turbidity as a result of increased sediment input,approaching the maximum level for clean water(5 NTU).Benthic macroinvertebrate communities declined in the immediate downstream vicinity of construction but are expected to recover soon given that turbidity recovered to pre-construction levels,and DO increased.These outcomes emphasize that environmental assessment is important not only for large-scale hydromodification but also for smaller scale stream modifications. | Bin Zhu Daniel S.Smith Anthony P.Benaquista Dylan M.Rossi Betsy M.Kadapuram Man Lok Yu Andrew S.Partlow Nathan R.Burtch | 2018 | Ecological Processes2018，7，1： | 1 |
| 19 | Completion of the genome sequence of Brucella abortus and comparison to the highly similar genomes of Brucella melitensis and Brucella suis显示文摘 | Hailing Shirley M Peterson-Burch Brooke D Bricker Betsy J | 2005 | Journal of Bacteriology2005，187，8： | 1 |
| 20 | 体重调整固定剂量普通肝素与低分子肝素治疗急性静脉血栓栓塞的比较显示文摘背景:普通肝素用于治疗急性静脉血栓栓塞时,通常在监测血凝下静脉输注给药,患者需要住院治疗。然而,体重调整后皮下注射固定剂量普通肝素可能既适用于住院也适用于门诊静脉血栓栓塞患者的治疗。
目的:确定皮下注射体重调整固定剂量普通肝素治疗静脉血栓栓塞是否与低分子肝素同样安全有效。设计、地点及患者:随机、开标、裁定者盲法、非劣效试验。708例急性静脉血栓栓塞患者来自加拿大和新西兰6所大学附属临床中心,年龄≥18岁。试验于1998年9月至2004年2月进行。在随机分组的患者中,11例从疗效分析中排除,8例从安全性分析中排除。
干预:普通肝素皮下注射初始剂量为333U/kg,以后给予固定剂量250U/kg,每12小时1次(n=345)。低分子肝素(依诺肝素或达肝素)按100IU/kg剂量皮下注射,每12小时1次(n=352)。两种治疗均可院外进行,配合华法林治疗3个月。
主要观测指标:随机分组后3个月内复发性静脉血栓栓塞事件及10天内严重出血情况。结果:普通肝素组有13例患者(3.8%)发生静脉血栓栓塞复发,而低分子肝素组有12例患者复发(3.4%;绝对差值,0.4%;95%可信区间,-2.6%~3.3%)。开始治疗后10天内普通肝素组有4例患者(1.1%)发生严重出血,而低分子肝素组有5例(1.4%;绝对差值,-0.3%;95%可信区间,-2.3%~1.7%)。院外治疗患者在普通肝素组占72%,低分子肝素组占68%。
结论:对于急性静脉血栓栓塞患者而言,皮下注射固定剂量普通肝素与低分子肝素一样安全有效,适于门诊治疗。 | Clive Kearon Jeffrey S. Ginsberg Jim A. Julian James Douketis Susan Solymoss Paul Ockelford Sharon Jackson Alexander G. Turpie Betsy MacKinnon Jack Hirsh Michael Gent 王春玲(译) 孙艺红(译) 胡大一(校) | 2007 | 美国医学会杂志(中文版)2007，26，5： | 1 |
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