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1Integrated approach to colorectal anastomotic leakage: Communication, infection and healing disturbances显示文摘Colorectal anastomotic leakage(CAL) remains a major complication after colorectal surgery. Despite all efforts during the last decades, the incidence of CAL has not decreased. In this review, we summarize the available strategies regarding prevention, prediction and intervention of CAL and categorize them into three categories: communication, infection and healing disturbances. These three major factors actively interact during the onset of CAL. We aim to provide an integrated approach to CAL based on its etiology. The intraoperative air leak test, intraoperative endoscopy, radiological examinations and stoma construction mainly aim to detect and to prevent communication between the intra- and extra-luminal content. Other strategies including postoperative drainage, antibiotics, and infectious-parameter evaluation are intended to detect and prevent anastomotic or peritoneal infection. Most currently available interventions for CAL focus on the control of communication and infection, while strategies targeting the healing disturbances such as lifestyle changes, oxygen therapy and evaluation of metabolic biomarkers still lack wide clinical application. This simplified categorization may contribute to an integrated understanding of CAL. We strongly believe that this integrated approach should be taken into consideration during clinical practice. An integrated approach to CAL could contribute to a better understanding of the etiology of CAL and eventually better patient outcome.Cloe L Sparreboom Zhou-Qiao Wu Jia-Fu Ji Johan F Lange 2016World Journal of Gastroenterology2016,22,32:9
2吻合口漏:预防、诊断及治疗显示文摘引言:在直肠癌的治疗方法中,手术切除仍是治疗直肠癌的主要手段。腹腔镜、吻合器的应用明显提高了保肛率。然而吻合口漏仍是最令病人及外科医生烦恼的并发症之一[1],因此,有效地预防及恰当地处理吻合口漏显得尤为重要。现从吻合口漏的诊断、及治疗等方面的现状及进展做一综述。1.吻合口漏的表现及诊断吻合口漏通常在术后5-8天出现典型的临床表现,但也有一些意外甚至有报道术后12天诊断为吻合口漏[2]。王亚琼 禹正杨 2015大家健康(学术版)2015,,5:0
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