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| 1 | Late biliary complications in human alveolar echinococcosis are associated with high mortality显示文摘AIM:To evaluate the incidence of late biliary complications in non-resectable alveolar echinococcosis(AE)under long-term chemotherapy with benzimidazoles.METHODS:Retrospective analysis of AE patients with biliary complications occurring more than three years after the diagnosis of AE.We compared characteristics of patients with and without biliary complications,analyzed potential risk factor for biliary complications and performed survival analyses.RESULTS:Ninety four of 148 patients with AE in Zurich had non-resectable AE requiring long-term benzimidazole chemotherapy,of which 26(28%)patients developed late biliary complications.These patients had a median age of 55.5(35.5-65)years at diagnosis of AE and developed biliary complications after 15(8.25-19)years of chemotherapy.The most common biliary complications during long-term chemotherapy were late-onset cholangitis(n=14),sclerosing cholangitis-like lesions(n=8),hepatolithiasis(n=5),affection of the common bile duct(n=7)and secondary biliary cirrhosis(n=7).Thirteen of the 26 patients had undergone surgery(including 12 resections)before chemotherapy.Previous surgery was a risk factor for late biliary complications in linear regression analysis(P=0.012).CONCLUSION:Late biliary complications can be observed in nearly one third of patients with non-resectable AE,with previous surgery being a potential risk factor.After the occurrence of late biliary complications,the median survival is only 3 years,suggesting that late biliary complications indicate a poor prognostic outcome. | Pascal Frei Benjamin Misselwitz Meher K Prakash Alain M Schoepfer Bettina M Prinz Vavricka Beat Müllhaupt Michael Fried Kuno Lehmann Rudolf W Ammann Stephan R Vavricka | 2014 | World Journal of Gastroenterology2014，20，19： | 5 |
| 2 | Prograte turbulence following s in patient s with idiopathic dilated cardiomyopathy显示文摘 | GRIMM W SCHMIDT G nostic significance of heart vent rieular premature beat MAISCH B | 2003 | J Cardiovasc Electrophysiol2003，14，： | 1 |
| 3 | Multidetector CT virtual bronchoscopy to grade tracheobronchial stenosis显示文摘 | Hanno H Beat W Martin S | 2002 | AJR2002，178，5： | 1 |
| 4 | Specific bacterial, archaeal, and eukaryotic communities in tidal-flat sediments along a vertical profile of several meters显示文摘 | Reinhard W Henrik S Beate K | 2006 | Applied and Environmental Microbiology2006，72，4： | 1 |
| 5 | Ti-TADDOLate-catalyzed, highly enanti- oseleetive addition of alkyl-and aryl-titanium derivatives to aldehydes 显示文摘 | Beat W Dieter S | 1994 | Tetrahedron1994，50，25： | 1 |
| 6 | Native mitochondrial creatine kinase forms octamaerie structure 显示文摘 | Jorg S Beat Z W | 1998 | J Biol Chem1998，263，16： | 1 |
| 7 | Evaluation of nun - formalin tissue fixation for molecular profiling studies 显示文摘 | Gillespie J W Beat C M Biehsel V E | 2002 | Am J Pathol2002，160，2： | 1 |
| 8 | Exploration of stress-induced immuno suppresion in chickens reveals both stress-resistant and stress-susceptible antigen responses显示文摘 | Heba E L Beat H E Thomas W J | 2003 | Veterinary Immunology and Immunopathology2003，95，： | 1 |
| 9 | Increased expression of CD40 ligand (CD154)on CD4+T cells as a marker of disease activity in rheumatoid arthritis显示文摘 | Beate B Gabriele W Klaus M H | 2003 | Ann Rheum Dis2003，62，3： | 1 |
| 10 | Is the diagnostic yield of upper GI endoscopy improved by the use of explicit panel-based appropriateness criteria?显示文摘 | Florian Froehlich Claude Repond Beat Müllhaupt John-Paul Vader Bernard Burnand Catherine Schneider Isabelle Pache Jo?l Thorens Jean-Pierre Rey Vanessa DeBosset Vincent Wietlisbach Michael Fried Robert W DuBois Robert H Brook Jean-Jacques Gonvers | 2000 | Gastrointestinal Endoscopy2000，，3： | 1 |
| 11 | Palatal bone support for orthodontic implant anchorage-a clinical and radiological study显示文摘 | Heinrich W Beat R | 1999 | Eur Orthod1999，21，1： | 1 |
| 12 | Zeolite-based materials for the selective catalytic reduction of NOx with hydrocarbons显示文摘 | Yvonne T Beate B Jens W | 1999 | Microporous and Mesoporous Materials1999，30，1： | 1 |
| 13 | HLA ‐typing, clinical, and immunological characterization of youth with type 2 diabetes mellitus phenotype from the German/Austrian DPV database显示文摘 | Wendy L Awa Bernard O Boehm Silke Rosinger Peter Achenbach Anette G Ziegler Stephanie Krause Thomas Meissner Susanne Wiegand Thomas Reinehr Thomas Kapellen Beate Karges Thomas Eiermann Edith Schober Reinhard W Holl | 2013 | Pediatr Diabetes2013，，8： | 1 |
| 14 | Muhidet ect or C T vir- tual bronchoscopy to grade tracheobronchial stenosis 显示文摘 | H anno H Beat W Martin S | 2002 | AJR2002，178，5： | 1 |
| 15 | HLA ‐typing, clinical, and immunological characterization of youth with type 2 diabetes mellitus phenotype from the German/Austrian DPV database显示文摘 | Wendy L Awa Bernard O Boehm Silke Rosinger Peter Achenbach Anette G Ziegler Stephanie Krause Thomas Meissner Susanne Wiegand Thomas Reinehr Thomas Kapellen Beate Karges Thomas Eiermann Edith Schober Reinhard W Holl | 2013 | Pediatr Diabetes2013，，8： | 1 |
| 16 | Actin, microtubules and focal adhesion dynamics during cell migration 显示文摘 | Bernhard W H Beat A I | 2003 | Int ] Biochem Cell Biol2003，359，1： | 1 |
| 17 | Estimation of emissivities in a two-dimensional irregular geometry by inverse radiation analysis using hybrid genetic algorithm显示文摘 | Kim K W Beat S W Kim M Y | 2004 | Journal of Quantitative Spectroscopy and Radiative Transfer2004，87，1： | 1 |
| 18 | Aetin, microtubules and focal ad- hesiondynamics during cell migration 显示文摘 | Bernhard W H Beat A I | 2003 | Int J Biochem Cell Biol2003，359，1： | 1 |
| 19 | Genome-wide comparative analysis of copia retrotransposons in Tritieeae, rice,and Arabidopsis re- veals conserved ancient evolutionary lineages and distinct dynamics of individual copia families显示文摘 | Thomas W Beat K | 2007 | Genome Research2007，17，： | 1 |
| 20 | Temporo-spatial distribution of blood vessels in human lumbar intervertebral discs显示文摘 | Andreas G. Nerlich Rainer Schaaf Beat W?lchli Norbert Boos | 2007 | European Spine Journal2007，，4： | 1 |
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