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    题名 作者 年代 出处 被引量
1滑动多层磁共振成像对原发性卵巢癌分期的应用研究显示文摘目的分析滑动多层磁共振成像(SMS-MRI)的技术特点,并探讨SMS-MRI在原发性卵巢癌分期中的价值。方法对15例卵巢癌患者术前行SMS-MRI扫描,扫描范围包括胸腹盆腔(从胸廓入口至盆底)。SMS-MRI扫描的主要序列有常规T_2WITSE序列、SMS-TIRM序列和SMSFLASH 2D压脂增强序列。SMS-MRI图像由两位放射科医师随机单盲阅片后进行分期诊断,并将其结果与手术病理结果对照。观察内容包括:(1)肿瘤定位(单侧或双侧);(2)局部浸润:子宫输卵管或其他盆腔组织受侵;(3)腹膜转移;(4)淋巴结转移;(5)远处转移。结果 15例均经组织病理学证实,其中浆液性囊腺癌9例,黏液性囊腺癌2例,子宫内膜样癌2例,透明细胞癌和颗粒细胞癌各1例。手术病理分期为Ⅰ期0例,Ⅱ期2例,Ⅲ期10例,Ⅳ期3例。以手术病理结果为金标准,SMS-MRI对于原发性卵巢癌总的分期准确率为100%(15/15)。SMS-MRI在卵巢癌的定位诊断、子宫输卵管局部浸润和远处转移等方面的符合率均为100%。结论结合SMS技术的MRI可在保证图像质量的情况下,在较短的时间内一次性完成体部胸腹盆腔扫描,能较准确的完成卵巢癌原发灶和转移的侦测和分期,为卵巢癌分期诊断提供了一项新的影像诊断选择。张伶 王仁法 Pache G 伍尧泮 Schaefer O Langer M 关键 2010影像诊断与介入放射学2010,19,3:6
214项比较西罗莫司洗脱支架和裸金属支架的临床试验的分析Kastrati A. Mehilli J. Pache J. 黄浙勇 2007世界核心医学期刊文摘(心脏病学分册)2007,0,8:3
3The importance of avoiding unnecessary right ventricular pacing in clinical practice显示文摘Symptomatic bradycardia is effectively treated with the implantation of a cardiac pacemaker. Although a highly successful therapy, during recent years there has been a focus on the negative effects associated with longterm pacing of the apex of the right ventricle(RV). It has been shown in both experimental and clinical studies that RV pacing leads to ventricular dyssynchrony, similar to that of left bundle branch block, with subsequent detrimental effects on cardiac structure and function, and in some cases adverse clinical outcomes such as atrial fibrillation, heart failure and death. There is substantial evidence that patients with reduced left ventricular function(LVEF) are at particular high risk of suffering the detrimental clinical effects of long-term RV pacing. The evidence is, however, incomplete, coming largely from subanalyses of pacemaker and implantable cardiac defibrillator studies. In this group of patients with reduced LVEF and an expected high amount of RV pacing, biventricular pacing(cardiac resynchronization therapy) devices can prevent the negative effects of RV pacing and reduce ventricular dyssynchrony. Therefore, cardiac resynchronization therapy has emerged as an attractive option with promising results and more clinical studies are underway. Furthermore, specific pacemaker algorithms, which minimize RV pacing, can also reduce the negative effects of RV stimulation on cardiac function and may prevent clinical deterioration.Finn Akerstrm Miguel A Arias Marta Pachón Jesús Jiménez-López Alberto Puchol Justo Juliá-Calvo 2013World Journal of Cardiology2013,5,11:3
4Outer membrane vesicles as an acellular vaccine against Acinetobacter baumannii显示文摘Michael J. McConnell Carlos Rumbo Germán Bou Jerónimo Pachón 2011Vaccine2011,,34:2
5Dendritic cell deficiencies persist seven months after SARS-CoV-2 infection显示文摘Severe Acute Respiratory Syndrome Coronavirus(SARS-CoV)-2 infection induces an exacerbated inflammation driven by innate immunity components.Dendritic cells(DCs)play a key role in the defense against viral infections,for instance plasmacytoid DCs(pDCs),have the capacity to produce vast amounts of interferon-alpha(IFN-α).In COVID-19 there is a deficit in DC numbers and IFN-αproduction,which has been associated with disease severity.In this work,we described that in addition to the DC deficiency,several DC activation and homing markers were altered in acute COVID-19 patients,which were associated with multiple inflammatory markers.Remarkably,previously hospitalized and nonhospitalized patients remained with decreased numbers of CD1c+myeloid DCs and pDCs seven months after SARS-CoV-2 infection.Moreover,the expression of DC markers such as CD86 and CD4 were only restored in previously nonhospitalized patients,while no restoration of integrinβ7 and indoleamine 2,3-dyoxigenase(IDO)levels were observed.These findings contribute to a better understanding of the immunological sequelae of COVID-19.Alberto Pérez-Gómez Joana Vitallé Carmen Gasca-Capote Alicia Gutierrez-Valencia María Trujillo-Rodriguez Ana Serna-Gallego Esperanza Muñoz-Muela María de los Reyes Jiménez-Leon Mohamed Rafii-El-Idrissi Benhnia Inmaculada Rivas-Jeremias Cesar Sotomayor Cristina Roca-Oporto Nuria Espinosa Carmen Infante-Domínguez Juan Carlos Crespo-Rivas Alberto Fernández-Villar Alexandre Pérez-González Luis Fernando López-Cortés Eva Poveda Ezequiel Ruiz-Mateos JoséMiguel Cisneros Sonsoles Salto-Alejandre Judith Berastegui-Cabrera Pedro Camacho-Martínez Carmen Infante-Domínguez Marta Carretero-Ledesma Juan Carlos Crespo-Rivas Eduardo Márquez JoséManuel Lomas Claudio Bueno Rosario Amaya JoséAntonio Lepe Jerónimo Pachón Elisa Cordero Javier Sánchez-Céspedes Manuela Aguilar-Guisado Almudena Aguilera Clara Aguilera Teresa Aldabo-Pallas Verónica Alfaro-Lara Cristina Amodeo Javier Ampuero María Dolores Avilés Maribel Asensio Bosco Barón-Franco Lydia Barrera-Pulido Rafael Bellido-Alba Máximo Bernabeu-Wittel Candela Caballero-Eraso Macarena Cabrera Enrique Calderón Jesús Carbajal-Guerrero Manuela Cid-Cumplido Yael Corcia-Palomo Juan Delgado Antonio Domínguez-Petit Alejandro Deniz Reginal Dusseck-Brutus Ana Escoresca-Ortega Fátima Espinosa Nuria Espinosa Michelle Espinoza Carmen Ferrándiz-Millón Marta Ferrer Teresa Ferrer Ignacio Gallego-Texeira Rosa Gámez-Mancera Emilio García Horacio García-Delgado Manuel García-Gutiérrez María Luisa Gascón-Castillo Aurora González-Estrada Demetrio González Carmen Gómez-González Rocío González-León Carmen Grande-Cabrerizo Sonia Gutiérrez Carlos Hernández-Quiles Inmaculada Concepción Herrera-Melero Marta Herrero-Romero Luis Jara Carlos Jiménez-Juan Silvia Jiménez-Jorge Mercedes Jiménez-Sánchez Julia Lanseros-Tenllado Carmina López Isabel López Álvaro López-Barrios Luis F.López-Cortés Rafael Luque-Márquez Daniel Macías-García Guillermo Martín-Gutiérrez Luis Martín-Villén JoséMolina Aurora Morillo María Dolores Navarro-Amuedo Dolores Nieto-Martín Francisco Ortega María Paniagua-García Amelia Peña-Rodríguez Esther Pérez Manuel Poyato Julia Praena-Segovia Rafaela Ríos Cristina Roca-Oporto Jesús F.Rodríguez María Jesús Rodríguez-Hernández Santiago Rodríguez-Suárez Ángel Rodríguez-Villodres Nieves Romero-Rodríguez Ricardo Ruiz Zida Ruiz de Azua Celia Salamanca Sonia Sánchez Víctor Manuel Sánchez-Montagut César Sotomayor Alejandro Suárez Benjumea Javier Toral 2021Cellular & Molecular Immunology2021,18,9:2
6Glucagon-like peptide-1 receptor imaging with [Lys 40 (Ahx-HYNIC- 99m Tc/EDDA)NH 2 ]-exendin-4 for the detection of insulinoma显示文摘Anna Sowa-Staszczak Dorota Pach Renata Miko?ajczak Helmut M?cke Agata Jabrocka-Hybel Agnieszka Stefańska Monika Tomaszuk Barbara Janota Aleksandra Gilis-Januszewska Maciej Ma?ecki Grzegorz Kamiński Aldona Kowalska Jan Kulig Andrzej Matyja Czes?aw Osuch Al 2013European Journal of Nuclear Medicine and Molecular Imaging2013,,4:2
7Subcutaneous implantable defibrillator: State-of-the art 2013显示文摘The subcutaneous implantable cardioverter-defibrillator(S-ICD)has recently been approved for commercial use in Europe,New Zealand and the United States.It is comprised of a pulse generator,placed subcutaneously in a left lateral position,and a parasternal subcutaneous lead-electrode with two sensing electrodes separated by a shocking coil.Being an entirely subcutaneous system it avoids important periprocedural and long-term complications associated with transvenous implantable cardioverter-defibrillator(TV-ICD)systems as well as the need for fluoroscopy during implant surgery.Suitable candidates include pediatric patients with congenital heart disease that limits intracavitary lead placements,those with obstructed venous access,chronic indwelling catheters or high infection risk,as well as young patients with electrical heart disease(e.g.,Brugada Syndrome,long QT syndrome,and hypertrophic cardiomyopathy).Nevertheless,given the absence of intracavitary leads,the S-ICD is unable to offer pacing(apart from shortterm post-shock pacing).It is therefore not suitable in patients with an indication for antibradycardia pacing or cardiac resynchronization therapy,or with a history of repetitive monomorphic ventricular tachycardia that would benefit from antitachycardia pacing.Current data from initial clinical studies and post-commercialization'real-life'case series,including over 700 patients,have so far been promising and shown that the S-ICD successfully converts induced and spontaneous ventricular tachycardia/ventricular fibrillation episodes with associated complication and inappropriate shock rates similar to that of TV-ICDs.Furthermore,by using far-field electrograms better tachyarrhythmia discrimination when compared to TV-ICDs has been reported.Future results from ongoing clinical studies will determine the S-ICD system’s long-term performance,and better define suitable patient profiles.Finn Akerstrm Miguel A Arias Marta Pachón Alberto Puchol Jesús Jiménez-Lópezl 2013World Journal of Cardiology2013,5,9:2
8Elevated plasma endothelin-1 levels and vascular dysregulation in patients with rheumatoed arthritis 显示文摘Pache M Schwarz HA Kaiser HJ 2002Med sei Monit2002,8,9:1
9Prevention of rifampicin resistance in Acinetobacter bau-mannii in an experimental pneumonia murine model,usingrifampicin associated with imipenem or sulbactam显示文摘Pachón-Ibáez ME Fernández-Cuenca F Docobo-Pérez F etal 2006J Anti-microb Chemother2006,58,3:1
10lntracoronary stentlng and angiographic results : strut thickness effect on restenosis outcome ( ISAR-STEREO-2 ) trial 显示文摘Pache J Kastrati A MehiUi J 2003J Am Coll Cardiol2003,41,8:1
11Asymmetry of basal ganglia in children with attention deficit hyperactivity disorder显示文摘Uhlkova P Pach I Vaneckova M 2007Neuro Endocrinol Lett2007,28,:1
12When Worlds Collide: The Internal Dynamics of Organizational Responses to Conflicting Institutional Demands 显示文摘PACHE A SANTOS F 2010Academy of Management Review2010,35,3:1
13Clopido- grel therapy in patients undergoing coronary stenting:value of a high - loading - dose regimen 显示文摘Pache J Kastrati A Mehilli J 2002Catheter Cardiovasc Interv2002,55,:1
14Lung recruitment and lung volume maintenance:a strategy for improving oxygenation ventilation and high-frequency Oscillation显示文摘Rimensberger P C Pache J C Mckerlie C 2000Intensive Care Med2000,26,6:1
15Listeria monocytogenes-infected human peripheral blood mononuclear cells produce IL-1beta,depending on listeriolysin O and NLRP3显示文摘Meixenberger K Pache F Eitel J 2010J Immunol2010,184,2:1
16Dual-energy CT virtual noncalcium technique:detecting posttraumatic bone marrow lesions--feasibility study显示文摘Pache G Krauss B Strohm P 0,,02:1
17Analysis of 14 trials comparing sirolimuseluting stents with bare-metal stents 显示文摘Kastrati A Mehilli J Pache J 2007N Engl J Med2007,356,:1
18Analysis of 14 trials comparing sirolimus- eluting stents with bare-metal stents显示文摘Kastrati A Mehilli J Pache J 2007N Engl J Med2007,356,:1
19Inside the hybrid organization: se- lective coupling as a response to competing institutional logics 显示文摘Pache A C Santos F 2013Academy of Management Journal2013,56,4:1
20Dual-energy CT virtual noncalcium technique: Detecting posttraumatic bone marrow lesions--feasibility study显示文摘Pache G Krauss B Strohm P 2010Radiology2010,256,2:1
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