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| 1 | 当归对大鼠脑缺血损伤保护作用的实验研究显示文摘探讨当归对大鼠脑缺血损伤是否具有保护作用。阻断大鼠右颈总动脉和大脑中动脉90min后恢复再灌,给予 25%当归注射液 7.5 mL静脉滴注 6 h。术后第 8天用图像处理技术测定脑梗死体积。结果显示当归治疗组梗死体积显著小于实验对照组。本实验首次证实当归具有缩小脑梗死体积的作用,其作用机制待深入研究阐明。 | 廖维靖 杨万同 周云峰 Frank Wiegand UlrichDirnagl | 1999 | 中草药1999，30，4： | 16 |
| 2 | 应用mTOR抑制剂西罗莫司治疗淋巴管畸形:系统评价显示文摘背景:广泛性淋巴管畸形是能引起破坏性并发症的低流量脉管畸形,这一畸形的治疗充满挑战性。本系统评价介绍了目前西罗莫司在治疗广泛性淋巴管畸形患者中的应用。方法:在MEDLINE和谷歌学术中检索自2017年7月以来有关西罗莫司治疗淋巴管畸形的研究。检索关键词包括"淋巴管畸形"、"淋巴管瘤"、"囊性水瘤"、"脉管畸形"、"低流量畸形"、"西罗莫司"、"雷帕霉素"和"mTOR抑制剂"。 | Wiegand S Wichmann G Dietz A 赵泽亮 | 2018 | 中国口腔颌面外科杂志2018，16，4： | 13 |
| 3 | Estimating steatosis and fibrosis: Comparison of acoustic structure quantification with established techniques显示文摘AIM:To compare ultrasound-based acoustic structure quantification(ASQ) with established non-invasive techniques for grading and staging fatty liver disease.METHODS:Type 2 diabetic patients at risk of nonalcoholic fatty liver disease(n = 50) and healthy volunteers(n = 20) were evaluated using laboratory analysis and anthropometric measurements, transient elastography(TE), controlled attenuation parameter(CAP), proton magnetic resonance spectroscopy(1H-MRS; only available for the diabetic cohort), and ASQ.ASQ parameters mode, average and focal disturbance(FD) ratio were compared with:(1) the extent of liver fibrosis estimated from TE and nonalcoholic fatty liver disease(NAFLD) fibrosis scores; and(2) the amount of steatosis, which was classified according to CAP values.RESULTS:Forty-seven diabetic patients(age 67.0±8.6 years;body mass index 29.4±4.5 kg/m2)with reliable CAP measurements and all controls(age 26.5±3.2 years;body mass index 22.0±2.7 kg/m2)were included in the analysis.All ASQ parameters showed differences between healthy controls and diabetic patients(P<0.001,respectively).The ASQ FD ratio(logarithmic)correlated with the CAP(r=-0.81,P<0.001)and 1H-MRS(r=-0.43,P=0.004)results.The FD ratio[CAP<250 d B/m:107(102-109),CAP between 250 and 300 d B/m:106(102-114);CAP between 300 and 350 d B/m:105(100-112),CAP≥350 d B/m:102(99-108)]as well as mode and average parameters,were reduced in cases with advanced steatosis(ANOVA P<0.05).However,none of the ASQ parameters showed a significant difference in patients with advanced fibrosis,as determined by TE and the NAFLD fibrosis score(P>0.08,respectively).CONCLUSION:ASQ parameters correlate with steatosis,but not with fibrosis in fatty liver disease.Steatosis estimation with ASQ should be further evaluated in biopsy-controlled studies. | Thomas Karlas Joachim Berger Nikita Garnov Franziska Lindner Harald Busse Nicolas Linder Alexander Schaudinn Bettina Relke Rima Chakaroun Michael Trltzsch Johannes Wiegand Volker Keim | 2015 | World Journal of Gastroenterology2015，21，16： | 9 |
| 4 | Acoustic radiation force impulse imaging (ARFI) for non-invasive detection of liver fibrosis: examination standards and evaluation of interlobe differences in healthy subjects and chronic liver disease显示文摘 | Thomas Karlas Cornelia Pfrepper Johannes Wiegand Christian Wittekind Marie Neuschulz Joachim M?ssner Thomas Berg Michael Tr?ltzsch Volker Keim | 2011 | Scandinavian Journal of Gastroenterology2011，，12： | 4 |
| 5 | Spatial distributions of tropical tree species in northern Vietnam under environmentally variable site conditions显示文摘Ecological interactions of species and thus their spatial patterns may differ between homogeneous and heterogeneous forests. To account for this, techniques of point pattern analysis were implemented on mapped locations of tree individuals from two 1-ha tropicalforest plots in Vietnam. We analyzed the effect of environmental heterogeneity on tree distributions; spatial distribution patterns of dominant species; inter-specific associations; and conspecific associations between life stages. Our analyses showed that: environmental conditions were homogeneous at plot 1 but heterogeneous at plot 2; in both plots, all six dominant species were aggregated at various scales up to 30 m, and tree species were aggregated at larger scales in the homogeneous site than in the heterogeneous site; attraction between pairs of species was remarkably higher at the homogeneous site while negative associations were more frequent in the heterogeneous site; some species, H. kurzii, T. ilicifolia(homogeneous plot) and D. sylvatica, S. wightianum(heterogeneous plot),showed a lack of early life-stage individuals near conspecific adults. Moreover, additional clustering of young individuals was independent from conspecific adults, except D. sylvatica in both sites. These findings are consistent with the Janzen-Connell hypothesis. Overall, habitat heterogeneity influences spatial patterns and inter-specific associations of the tree species and evidences of self-thinning are shown in most species. | Nguyen Hong Hai Kerstin Wiegand Stephan Getzin | 2014 | Journal of Forestry Research2014，25，2： | 4 |
| 6 | 青少年特发性脊柱侧凸患者治疗前后的椎旁表面肌电活动的研究显示文摘目的探讨青少年特发性脊柱侧凸的患者在包括手法在内的综合治疗前后的脊柱旁肌电活动特点。方法选择9例确诊的特发性脊柱侧凸的患者,在乳突下、C1、T1、T3、T6、T9、T12、L3、L5位置记录为期24周的综合治疗前后的椎旁的肌电活动。结果在综合治疗前:7例上位凸起的对侧枕下肌电活动过高;6例下位凸起侧的L5/S1段肌电活动过高;6例从C5到L3单侧肌电活动过高。所有患者过高肌电活动发生在两弯曲中的一个的凹侧。综合治疗后:左右枕下SEMG值对称。上位或下位弯曲的SEMG值要么对称,要么在凸侧肌电活动过高。同侧L5/S1的SEMG值与下位弯曲凸侧一样。对治疗前后的SEMG值进行配对T检验,P<0.001。在前两周,患者过高肌电活动抑制很明显。经过7周的治疗,从凹侧至凸侧的过高肌电活动的交换在所有患者都明显并保持到治疗结束。结论综合治疗可以使凹侧的肌电活动过高转变为双侧平衡或凸侧肌电活动过高时,弯曲发展可以被阻止。一旦平衡建立,弯曲的阻止和活动的交换就会贯穿整个治疗过程。 | Raymond Wiegand D .C . | 2005 | 颈腰痛杂志2005，26，3： | 4 |
| 7 | Non-invasive evaluation of hepatic manifestation in Wilson disease with transient elastography, ARFI, and different fibrosis scores显示文摘 | Thomas Karlas Maria Hempel Michael Tr?ltzsch Dominik Huster Peter Günther Hannelore Tenckhoff Joachim M?ssner Thomas Berg Volker Keim Johannes Wiegand | 2012 | Scandinavian Journal of Gastroenterology2012，，11： | 2 |
| 8 | Label-retaining liver cancer cells are relatively resistant to sorafenib显示文摘 | Hong-Wu Xin Chenwi M Ambe Danielle M Hari Gordon W Wiegand Tyler C Miller Jin-Qiu Chen Andrew J Anderson Satyajit Ray John E Mullinax Tomotake Koizumi Russell C Langan Douglas Burka Michelle A Herrmann Paul K Goldsmith Alexander Stojadinovic Udo Rudloff S | 2013 | Gut2013，，12： | 2 |
| 9 | Intra-aortic balloon pump in patients with acute myocardial infarction complicated by cardiogenic shock: results of the ALKK-PCI registry显示文摘 | Uwe Zeymer Mathias Hochadel Karl-Eugen Hauptmann Klaus Wiegand Burghard Schuhmacher Johannes Brachmann Anselm Gitt Ralf Zahn | 2013 | Clinical Research in Cardiology2013，，： | 2 |
| 10 | Assessment of shooting distance on the basis of bloodstain analysis and histological examinationg显示文摘 | Kleiber M Stiller D Wiegand P | | 0，，： | 2 |
| 11 | Development and evaluation of simple models for flow,turbulence and pollutant concentration fields within an urban street canyon显示文摘 | Yamartino R J G Wiegand | 1986 | Atmospheric Environment1986，20，： | 2 |
| 12 | Effect of Different Calcination Temperatures and Post Annealing on the Properties of Acetic Acid Based Sol-Gel (Na_(0.5)K_(0.5))NbO_3(NKN) Thin Films显示文摘(Na0.5K0.5)NbO3(NKN) lead free thin films were synthesized by means of an acetic acid based sol-gel process on Pt/Ti/SiO2 /Si substrates. Na-acetate, K-acetate and Nb-pentaethoxide were used as metal precursors and acetic acid as the solvent. The effect of different calcination temperatures on the properties of the NKN films was investigated by X-ray diffraction, scanning electron microscopy, leakage current and hysteresis measurements. Low calcination temperatures led to low currents at high electric fields whereas high calcination temperatures led to low currents at low electric fields. Based on these findings calcination at low temperature was combined with a post annealing treatment. Low leakage currents of 4×10-4 A/cm2 at 150 kV/cm and 2Pr and 2Ec values of 28 μC/cm2 and 150 kV/cm, respectively, could be obtained. All films were single phase NKN with random crystal orientations and no crack or pore formation was visible on the surface. | Sebastian Wiegand Stefan Flege Olaf Baake Wolfgang Ensinger | 2013 | Journal of Materials Science & Technology2013，29，2： | 2 |
| 13 | Rate constrained coder control and comparison of video coding standards显示文摘 | WIEGAND T SCHWARZ H ANTHONY J | 2003 | IEEE Transaction on Circuits and Systems for Video Technology2003，13，7： | 1 |
| 14 | Review on fluoride-releasing restorative materials--fluoride release and uptake characteristics, antibacterial activity and influence on caries formation显示文摘 | Wiegand A Buchalla W Attin T | 2007 | Dent Mater2007，23，3： | 1 |
| 15 | Uptake of the cyanobaeterial hepatotoxin mierocystin - LR by aquatic macrophytes 显示文摘 | PFLUGMACHER S WIEGAND C BEATTIE KA | 1998 | J Appl Bot1998，72，： | 1 |
| 16 | Evaluation of the influence of housefly maggot meal (magmeal) diets on catalase,glutathione S-transferase and glycogen concentration in the liver of Oreochromis niloticus fingerling显示文摘 | Ogunji J O Nimptsch J Wiegand C | 2007 | Comp Biochem Physiol-Part A:Molec Integrat Physiol2007，147，4： | 1 |
| 17 | Rate-distortion optimization for video compression 显示文摘 | SULLIVAN Gary WIEGAND Thomas | 1998 | IEEE Signal Processing Magazine1998，15，11： | 1 |
| 18 | New model of tumor angiogenesis :dynamic balance between vessel regression and growth mediated by angiopoietins and VEGF显示文摘 | Holash J Wiegand SJ YancopoulosGD etal | 1999 | Oncogene1999，18，： | 1 |
| 19 | Cardiovaseular risk in 26 008 EuroPean overweight children as established by a multieenter database显示文摘 | Allemand D WiegandS Reinehr T | 2008 | Obesity(Silve Spring)2008，16，7： | 1 |
| 20 | ARID1A mutations in edometriosis-associatcd ovarian carcinomas显示文摘 | Wiegand K C Shah S P A1-Agha O M | 2010 | N Engl J Med2010，363，： | 1 |
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