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| 1 | 在血压控制不良的高血压患者中使用数字化干预的家庭和在线血压管理:随机对照试验显示文摘HOME BP试验(The home and online management and evaluation of blood pressure)的目的是评估在初级预防中结合自我监测和自我管理的数字化干预在高血压管理中的作用。研究者纳入英国76个治疗中心经过治疗但血压控制不好(>140/90 mm Hg, 1 mm Hg=0.133 kPa)并能上网的患者622例,进行自动确定主要终点的公开随机对照试验。 | McMa-nus RJ Little P Stuart B Morton K Raftery J Kelly J Bradbury K Zhang J Zhu S Murray E May CR Mair FS Michie S Smith P Band R Ogburn E AllenJ Rice C Nut-tall J Williams B Yardley L 陈嘉睿(译) 叶鹏(审校) | 2021 | 中华高血压杂志2021，29，5： | 15 |
| 2 | Regional Soil Mapping Using Multi-Grade Representative Sampling and a Fuzzy Membership-Based Mapping Approach显示文摘High-resolution and detailed regional soil spatial distribution information is increasingly needed for ecological modeling and land resource management. For areas with no point data, regional soil mapping includes two steps: soil sampling and soil mapping. Because sampling over a large area is costly, efficient sampling strategies are required. A multi-grade representative sampling strategy, which designs a small number of representative samples with different representative grades to depict soil spatial variations at different scales,could be a potentially efficient sampling strategy for regional soil mapping. Additionally, a suitable soil mapping approach is needed to map regional soil variations based on a small number of samples. In this study, the multi-grade representative sampling strategy was applied and a fuzzy membership-weighted soil mapping approach was developed to map soil sand percentage and soil organic carbon(SOC) at 0–20 and 20–40 cm depths in a study area of 5 900 km2 in Anhui Province of China. First, geographical sub-areas were delineated using a parent lithology data layer. Next, fuzzy c-means clustering was applied to two climate and four terrain variables in each stratum. The clustering results(environmental cluster chains) were used to locate representative samples. Evaluations based on an independent validation sample set showed that the addition of samples with lower representativeness generally led to a decrease of root mean square error(RMSE). The declining rates of RMSE with the addition of samples slowed down for 20–40 cm depth, but fluctuated for 0–20 cm depth. The predicted SOC maps based on the representative samples exhibited higher accuracy, especially for soil depth 20–40 cm, as compared to those based on legacy soil data. Multi-grade representative sampling could be an effective sampling strategy at a regional scale. This sampling strategy, combined with the fuzzy membership-based mapping approach, could be an optional effective framework for regional soil property mapping. A more detailed and accurate soil parent material map and the addition of environmental variables representing human activities would improve mapping accuracy. | YANG Lin A-Xing ZHU ZHAO Yuguo LI Decheng ZHANG Ganlin ZHANG Shujie Lawrence E. BAND | 2017 | Pedosphere2017，27，2： | 5 |
| 3 | Nexus of signaling and endocytosis in oncogenesis driven by non-small cell lung cancer-associated epidermal growth factor receptor mutants显示文摘Epidermal growth factor receptor(EGFR) controls a wide range of cellular processes, and aberrant EGFR signaling as a result of receptor overexpression and/or mutation occurs in many types of cancer. Tumor cells in non-small cell lung cancer(NSCLC) patients that harbor EGFR kinase domain mutations exhibit oncogene addiction to mutant EGFR, which confers high sensitivity to tyrosine kinase inhibitors(TKIs). As patients invariably develop resistance to TKIs, it is important to delineate the cell biological basis of mutant EGFR-induced cellular transformation since components of these pathways can serve as alternate therapeutic targets to preempt or overcome resistance. NSCLC-associated EGFR mutants are constitutively-active and induce ligandindependent transformation in nonmalignant cell lines. Emerging data suggest that a number of factors are critical for the mutant EGFR-dependent tumorigenicity, and bypassing the effects of TKIs on these pathways promotes drug resistance. For example, activation of downstream pathways such as Akt, Erk, STAT3 and Src is critical for mutant EGFR-mediated biological processes. It is now well-established that the potency and spatiotemporal features of cellular signaling by receptor tyrosine kinases such as EGFR, as well as the specific pathways activated, is determined by the nature of endocytic traffic pathways through which the active receptors traverse. Recent evidence indicates that NSCLCassociated mutant EGFRs exhibit altered endocytic trafficking and they exhibit reduced Cbl ubiquitin ligasemediated lysosomal downregulation. More recent work has shown that mutant EGFRs undergo ligand-independent traffic into the endocytic recycling compartment, a behavior that plays a key role in Src pathway activation and oncogenesis. These studies are beginning to delineate the close nexus between signaling and endocytic traffic of EGFR mutants as a key driver of oncogenicprocesses. Therefore, in this review, we will discuss the links between mutant EGFR signaling and endocytic properties, and introduce potential mechanisms by which altered endocytic properties of mutant EGFRs may alter signaling and vice versa as well as their implications for NSCLC therapy. | Byung Min Chung Eric Tom Neha Zutshi Timothy Alan Bielecki Vimla Band Hamid Band | 2014 | World Journal of Clinical Oncology2014，5，5： | 3 |
| 4 | The polycomb group protein Bmi-1 represses the tumor suppressor PTEN and induces epithelial-mesenchymal transition in human nasopharyngeal epithelial cells显示文摘 | Song Li-Bing Li Jun Liao Wen-Ting Feng Yan Yu Chun-Ping Hu Li-Juan Kong Qing-Li Xu Li-Hua Zhang Xing Liu Wan-Li Li Man-Zhi Zhang Ling Kang Tie-Bang Fu Li-Wu Huang Wen-Lin Xia Yun-Fei Tsao Sai Wah Li Mengfeng Band Vimla Band Hamid Shi | 2009 | Journal of Clinical Investigation2009，，12： | 2 |
| 5 | Leakage tests of the stainless steel vessels of the antineutrino detectors in the Daya Bay reactor neutrino experiment显示文摘The antineutrino detectors for the Daya Bay reactor neutrino experiment are liquid scintillator detectors designed to detect electron anti-neutrino via inverse beta interactions with high efficiency and low backgrounds.Since the antineutrino detector will be installed and immerged in water Cherenkov detector and will run for 3 to 5 years,water tightness is critical to the successful operation of the antineutrino detectors.A special seal technique was used for this purpose.Three leak checking methods have been employed to ensure the seal quality.This paper describes the sealing method and leakage testing results. | CHEN XiaoHui LUO XiaoLan HENG YueKun WANG LingShu TANG Xiao MA XiaoYan ZHUANG HongLin BAND Henry R. CHERWINKA Jeff J. XIAO Qiang HEEGER Karsten M. | 2013 | Science China(Technological Sciences)2013，56，1： | 2 |
| 6 | A nonlinear beam equation显示文摘 | ACKLEH A S BANDS H T PINTER G A | 2002 | Applied Mathematics Letters2002，，15： | 2 |
| 7 | BLIND AND INTERNET显示文摘BLINDANDINTERNETBLINDANDINTERNETZhaoGuanglu(ChineseAcademyofMedicalSciencesandPekingUnionMedicalCollege,Beijing100730China)In... | Qin-zhang Ding(The Department of Neuropsychiatry.Second Affiliated Hospital of Hebei Medical UniversityShijiazhuang. Heibe, 050000 China)In china a and all of the world, it is always using cloth bands to restrain activities of thelimbs in the patient | 1995 | Chinese Journal of Biomedical Engineering(English Edition)1995，4，4： | 2 |
| 8 | Patellectomy after total knee athroplasty显示文摘 | Chang MA Band JA Tmusdale RT | 2005 | Clin Orthop Reht Res2005，440，2： | 1 |
| 9 | Human papillomavirus DNAs immortalize normal human mammary epithelial cells and reduce their growth factor requirements显示文摘 | Band V Zajchowski D Kulesa V | 1990 | Proc Natl Acad Sci USA1990，87，： | 1 |
| 10 | Resonance light scattering and derived techniques in analytical chemistry: past, present, and future显示文摘 | Lu W Fernandez Band B S Yu Y | 2007 | Microchim Acta2007，158，： | 1 |
| 11 | Keratins as markers that distinguish normal and tumor - derived mammary epithelial cells显示文摘 | Trask DK Band W | 1990 | Proc Natl Sci USA1990，87，： | 1 |
| 12 | Direct Determination of Saccharin and Acesulfame-K in Sweeteners and Fruit Juices Powders显示文摘 | Natalia E. Llamas María S. Nezio Miriam E. Palomeque Beatriz S. Fernández Band | 2008 | Food Analytical Methods2008，，1： | 1 |
| 13 | 查看详情显示文摘 | Band Y B Tfippenbach M Burke J P Julienne P S | | 0，，： | 1 |
| 14 | Assessment of adult cancer pain: shortcoming of current methods显示文摘 | DESCHAMPS M BAND P R COLDMAN A J | 1998 | Pain1998，32，2： | 1 |
| 15 | Forest ecosystem process at the watershed scale: Basis for distributed simulation显示文摘 | Band L E Peterson D L Running S W etal | 1991 | Ecological Modelling1991，56，： | 1 |
| 16 | Reversibility of bronchial marked atypia:implication for chemopre-vention显示文摘 | BAND P R FELDSTEIN M SACCOMANNO G | 1986 | Cancer Detect Prev1986，9，12： | 1 |
| 17 | BATSE observations of gamma-ray burst spectra 1-Spectral diversity 显示文摘 | BAND D MATTESON J FORD L | 1993 | ApJ1993，413，1： | 1 |
| 18 | Human papilloma virus DNAs immortalize normal human mammary epithelial cell and reduce their growth factor requirements显示文摘 | BAND V ZAJCHOWSKI D KULESA V | 1990 | Proc Natl Acad Sci USA1990，87，1： | 1 |
| 19 | Citrobacter diversus brain abscess and men- ingitis in neonates显示文摘 | Graham DR Band JD | 1981 | JAMA1981，245，19： | 1 |
| 20 | E7 protein of human papil- loma virus-16 induces degradation of retinoblastoma pro- tein through the ubiquitin-proteasome pathway 显示文摘 | Boyer SN Wazer DE Band V | 1996 | Cancer Res1996，56，20： | 1 |
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